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https://www.readbyqxmd.com/read/30517410/degree-of-risk-for-foot-ulcer-due-to-diabetes-nursing-assessment
#1
Maria do Livramento Saraiva Lucoveis, Mônica Antar Gamba, Maria Angela Boccara de Paula, Ana Beatriz Pinto da Silva Morita
OBJECTIVE: To classify the level of risk for foot ulcers in people with diabetes mellitus and identify their main predictive risk factors. METHOD: Exploratory, descriptive study, in which patients were assessed in a municipal ambulatory of São Paulo through nursing consultation, following the guidelines of the International Consensus on the Diabetic Foot. Data were descriptively analyzed. RESULTS: The analyzed population was composed of 50 longevous and retired people, with household income of up to two minimum wages, with dermato-neurofunctional risk factors and unfavorable clinical indicators, and 66% had Risk 1; 16% Risk 2; 6% Risk 3 and 12% Risk 4...
November 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/30417509/evaluation-of-the-efficacy-of-microneedle-fractional-radiofrequency-in-turkish-patients-with-atrophic-facial-acne-scars
#2
Emel Bulbul Baskan, Asli Akin Belli
BACKGROUND: Scarring is an undesirable and severe complication of acne resulting in loss of self-esteem in young people. Although microneedle fractional radiofrequency (MFR) system has emerged as a good option to treat acne scars in recent years, it was examined in a few studies which were commonly from Asian countries. AIMS: We sought to evaluate the efficacy of MFR in Turkish patients with facial acne scars. METHODS: Nine patients with atrophic facial acne scars treated with MFR device were included in the study...
November 11, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/30388700/access-to-innovative-medicines-for-metastatic-melanoma-worldwide-melanoma-world-society-and-european-association-of-dermato-oncology-survey-in-34-countries
#3
L Kandolf Sekulovic, J Guo, S Agarwala, A Hauschild, G McArthur, G Cinat, A Wainstein, C Caglevic, P Lorigan, H Gogas, M Alvarez, R Duncombe, C Lebbe, K Peris, P Rutkowski, A Stratigos, A-M Forsea, L De La Cruz Merino, M Kukushkina, R Dummer, C Hoeller, C Gorry, L Bastholt, D Herceg, B Neyns, R Vieira, P Arenberger, M Bylaite-Bucinskiene, N Babovic, M Banjin, K Putnik, V Todorovic, K Kirov, J Ocvirk, A Zhukavets, A Ymeri, I Stojkovski, C Garbe
According to data from recent studies from Europe, a large percentage of patients have restricted access to innovative medicines for metastatic melanoma. Melanoma World Society and European Association of Dermato-oncology conducted a Web-based survey on access to first-line recommended treatments for metastatic melanoma by current guidelines (National Comprehensive Center Network, European Society for Medical Oncology [ESMO] and European Organization for Research and Treatment of Cancer/European Association of Dermato-oncology/European dermatology Forum) among melanoma experts from 27 European countries, USA, China, Australia, Argentina, Brazil, Chile and Mexico from September 1st, 2017 to July 1st, 2018...
October 30, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/30353297/-andrology-in-oncological-diseases
#4
REVIEW
T Weberschock, S Grunewald, F Ochsendorf
In dermato-oncological treatment there are many gonadotoxic interventions. Alkylating and hormonally active substances as well as gonadal irradiation, in particular, are known to have a fertilization-limiting effect in men. Since 2017 certified skin cancer centers in Germany therefore have the task to implement counselling on preservation of fertility. This is supported by the S2k guidelines on preservation of fertility in oncological treatment. Because recommendation of the various interventions from the dermato-oncological guidelines are dependent on the stage, the authors advocate at least the question "Is the desire to have children of interest to you?" when patients reach the appropriate stage...
October 23, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/30159073/schizophrenia-as-potential-trigger-for-melanoma-development-and-progression-the-psycho-neuro-endocrine-oncology-p-n-e-o-network
#5
Georgi Tchernev, Ilia Lozev, Ivanka Temelkova, Svetoslav Chernin, Irina Yungareva
BACKGROUND: Skin, nervous tissue, dopamine and melanoma share a common neuroectodermal origin. Hence, processes that modulate nervous tissue formation, patient mental status, motor regulation of individuals, and skin cancerogenesis are inextricably linked. Psycho-neuro-endocrine oncology (or dermato-oncology), i.e. P.N.E.O., is a new model or trend in medicine and science presented for the first time in the world literature by us, that aims to examine the relationship between the mental state, the hormones and the malignant transformation...
August 20, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/30140957/primary-leiomyosarcoma-of-the-skin-a-comprehensive-review-on-diagnosis-and-treatment
#6
REVIEW
Martina Zacher, Markus V Heppt, Titus J Brinker, Kinan M Hayani, Michael J Flaig, Carola Berking
Sarcomas are a heterogeneous group of mesenchymal tumors which can affect bone and soft tissue. Leiomyosarcoma (LMS) is a rare subtype localized to the skin or subcutaneous tissue. Due to the heterogeneity of sarcomas, reviews and guidelines with an in-depth focus specifically on primary LMS of the skin are sparse. This article is intended to provide an up to date and systematic overview on diagnosis, treatment, and surveillance of this rare entity to provide a framework for decision making and management for dermato-oncologists...
August 23, 2018: Medical Oncology
https://www.readbyqxmd.com/read/29898593/cutaneous-squamous-cell-carcinoma-italian-guidelines-by-sidemast-adapted-to-and-updating-eado-edf-eortc-guidelines
#7
Ketty Peris, Mauro Alaibac, Giuseppe Argenziano, Alessandro Di Stefani, Maria C Fargnoli, Pasquale Frascione, Giulio Gualdi, Caterina Longo, Elvira Moscarella, Luigi Naldi, Giovanni Pellacani, Nicola Pimpinelli, Pietro Quaglino, Marzia Salgarello, Pietro Sollena, Vincenzo Valentini, Iris Zalaudek, Pier G Calzavara Pinton
No abstract text is available yet for this article.
June 11, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29883464/in-situ-t-regulatory-cells-and-th17-cytokines-in-paired-samples-of-leprosy-type-1-and-type-2-reactions
#8
Maurício Barcelos Costa, Emerith Mayra Hungria, Aline Araújo Freitas, Ana Lúcia O M Sousa, Juliano Jampietro, Fernando A Soares, Mariane M A Stefani
Leprosy is a complex chronic, infectious dermato-neurological disease that affects the skin and peripheral nerves especially during immuno-inflammatory episodes known as type 1/T1R and type 2/T2R reactions. This study investigated the in situ expression of CD25+Foxp3+ Treg cells and TGF-β1, IFN-γ, IL-17 in leprosy T1R and T2R. Tregs were evaluated in 114 skin biopsies from 74 leprosy patients: 56 T1R (28-paired reaction-free/reactional biopsies, 28 unpaired T1R), 18 T2R (12 paired reaction-free/reactional biopsies, 6 unpaired T2R)...
2018: PloS One
https://www.readbyqxmd.com/read/29882592/is-a-specific-eyelid-patch-test-series-useful-results-of-a-french-prospective-study
#9
Haudrey Assier, Florence Tetart, Martine Avenel-Audran, Annick Barbaud, Marie-Christine Ferrier-le Bouëdec, Françoise Giordano-Labadie, Brigitte Milpied, Emmanuelle Amsler, Evelyne Collet, Pascal Girardin, Angèle Soria, Julie Waton, François Truchetet, Jean-Luc Bourrain, Gwendeline Gener, Claire Bernier, Nadia Raison-Peyron
BACKGROUND: Eyelids are frequent sites of contact dermatitis. No prospective study focused on eyelid allergic contact dermatitis (EACD) has yet been published, and this topic has never been studied in French patients. OBJECTIVES: To prospectively evaluate the usefulness of an eyelid series in French patients patch tested because of EACD, and to describe these patients. METHODS: We prospectively analysed standardized data for all patients referred to our departments between September 2014 and August 2016 for patch testing for suspected EACD as the main reason...
June 8, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29795621/willingness-to-pay-for-a-cure-of-low-risk-melanoma-patients-in-germany
#10
Matthias Augustin, Christine Blome, Andrea Forschner, Ralf Gutzmer, Axel Hauschild, Lucie Heinzerling, Elisabeth Livingstone, Carmen Loquai, Dirk Schadendorf, Jochen Utikal, Tobias Wagner, Sophia Wilden, Katharina C Kähler
Malignant melanoma is potentially life-threatening but in most cases curable if detected early. Willingness to pay (WTP) is a preference-based construct that reflects burden of disease by assessment of the monetary value for a hypothetical cure from disease. Since WTP (directly as total amount of money) has not been assessed so far in patients with low risk melanoma, it was interesting to gain insights in this patient population and then, in a second step, compare it directly with the WTP of their treating dermato-oncologists...
2018: PloS One
https://www.readbyqxmd.com/read/29765962/value-of-eponyms-in-dermato-trichological-nomenclature
#11
REVIEW
Ralph M Trüeb
Traditionally, syndromes have been named after the physician who originally identified the condition. These are referred to as eponymous syndromes. Nevertheless, the term eponym is to be regarded in a broader sense, since - by definition - an eponym is a person, place, or thing after whom or which something is named. Accordingly, some eponymous syndromes do not refer to the physician who originally reported the condition, but alternatively to the indicator patient, a geographic location, or a historical, literary, or mythological context...
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29678378/desquamative-gingivitis-clinical-findings-and-diseases
#12
REVIEW
Andrea D Maderal, Paul Lee Salisbury, Joseph L Jorizzo
Desquamative gingivitis is a clinical finding with several potential etiologies. Among the most common are oral lichen planus, cicatricial pemphigoid, and pemphigus vulgaris, though various other differential diagnoses exist. The presence of desquamative gingivitis often results in poor oral hygiene, which can have downstream consequences, including periodontitis and tooth loss. Though certain mucosal findings may be suggestive of a particular diagnosis, a thorough history, physical examination, and appropriate dermato- and immunopathologic assessment is necessary for narrowing this broad differential diagnosis...
May 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29650221/lymph-node-dissection-in-patients-with-melanoma-and-sentinel-lymph-node-metastasis-an-updated-evidence-based-decision-algorithm
#13
D Moreno-Ramírez, A Boada, L Ferrándiz, E Samaniego, G Carretero, E Nagore, P Redondo, P Ortiz-Romero, J Malvehy, R Botella-Estrada
Recent publication of the results of clinical trials in which lymph node dissection was not associated with any survival benefit in patients with sentinel node metastasis makes it necessary to reconsider the treatment of patients with melanoma. This article provides an update on the available evidence on the diverse factors (routes of metastatic spread, predictors, adjuvant therapy, etc.) that must be considered when treating patients with sentinel node-positive melanoma. The authors propose a decision-making algorithm for use in this clinical setting...
June 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29648669/a-clinical-prediction-model-for-surgical-site-infections-in-dermatological-surgery
#14
Xiaomeng Liu, Nicole W J Kelleners-Smeets, Melissa Sprengers, Vishal Hira, Klara Mosterd, Patty J Nelemans
To adequately identify patients at risk for surgical site infection in dermatological surgery and effectively prescribe antibiotic prophylaxis, a prediction model may be helpful. Such a model was developed using data from 1,407 patients who underwent dermatological surgery without antibiotic prophylaxis. The multivariable logistic regression model included type of closure, tumour location and defect size as risk factors. Bootstrapping was used for internal validation. The overall performance of the model was good, with an area under the curve of 84...
July 11, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29624652/religious-stigmata-a-dermato-psychiatric-approach-and-differential-diagnosis
#15
REVIEW
Elio Kechichian, Elie Khoury, Sami Richa, Roland Tomb
BACKGROUND: Stigma refers to the wounds reproduced on the human body, similar to the ones inflicted on the Christ during his crucifixion, on the palms, soles, and head, as well as the right or the left side of the chest, the lips and, the back. Whether they are genuine or fabricated, stigmata are still considered a medical enigma. OBJECTIVE: To summarize and analyze all available medical data about stigmata, integrating both its dermatological and psychiatric features...
August 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29619437/risk-factors-of-vulvovaginal-candidiasis-in-dermato-venereology-outpatients-clinic-of-soetomo-general-hospital-surabaya-indonesia
#16
Dharin Serebrina Arfiputri, Afif Nurul Hidayati, Samsriyaningsih Handayani, Evy Ervianti
Background: Vulvovaginal Candidiasis (VVC) is one-third of vaginitis case. About 75% of women will have at least one episode of VVC. Complication of VVC can be unfavorable to impact the patient's quality of life. Knowing its risk factors can prevent someone suffering from pathological VVC and its sequelae. The purpose of this study was to identify risk factors of VVC. Materials and Methods: A descriptive retrospective study was conducted by total sampling to 213 medical records of VVC patients from 869 fluor albus patients in Sexually Transmitted Infection (STI) Division, Dermatology and Venereology Outpatient Clinic in Dr...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29565968/blood-coagulation-abnormalities-in-multibacillary-leprosy-patients
#17
Débora Santos da Silva, Lisandra Antonia Castro Teixeira, Daniela Gois Beghini, André Teixeira da Silva Ferreira, Márcia de Berredo Moreira Pinho, Patricia Sammarco Rosa, Marli Rambaldi Ribeiro, Monica Di Calafiori Freire, Mariana Andrea Hacker, José Augusto da Costa Nery, Maria Cristina Vidal Pessolani, Ana Maria Freire Tovar, Euzenir Nunes Sarno, Jonas Perales, Fernando Augusto Bozza, Danuza Esquenazi, Robson Queiroz Monteiro, Flavio Alves Lara
BACKGROUND: Leprosy is a chronic dermato-neurological disease caused by Mycobacterium leprae infection. In 2016, more than 200,000 new cases of leprosy were detected around the world, representing the most frequent cause of infectious irreversible deformities and disabilities. PRINCIPAL FINDINGS: In the present work, we demonstrate a consistent procoagulant profile on 40 reactional and non-reactional multibacillary leprosy patients. A retrospective analysis in search of signs of coagulation abnormalities among 638 leprosy patients identified 35 leprosy patients (5...
March 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29564874/rheumatologic-dermato-patho-logy-the-microscope-as-a-help-for-the-clinician
#18
Franco Rongioletti
No abstract text is available yet for this article.
April 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29516114/-acute-emergencies-in-oncology
#19
REVIEW
D Nashan, S Dengler
The spectrum of dermato-oncological emergencies is multifaceted. They are particularly observed in cases with malignant melanoma due to the large number of patients and prolonged survival rates that are associated with new therapies for advanced disease. Dermato-oncological patients present to the hospital with symptoms like nausea and emesis, unexpected neurological deficits, various gastrointestinal problems, and even acute abdomen, acute breathlessness, or hemoptysis. Furthermore, emergencies can be caused by hematological problems like anemia and leukopenia...
May 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29507073/topical-treatment-for-cutaneous-leishmaniasis-dermato-pharmacokinetic-lead-optimization-of-benzoxaboroles
#20
Katrien Van Bocxlaer, Eric Gaukel, Deirdre Hauser, Seong Hee Park, Sara Schock, Vanessa Yardley, Ryan Randolph, Jacob J Plattner, Tejal Merchant, Simon L Croft, Robert T Jacobs, Stephen A Wring
Cutaneous leishmaniasis (CL) is caused by several species of the protozoan parasite Leishmania , affecting an estimated 10 million people worldwide. Previously reported strategies for the development of topical CL treatments have focused primarily on drug permeation and formulation optimization as the means to increase treatment efficacy. Our approach aims to identify compounds with antileishmanial activity and properties consistent with topical administration. Of the test compounds, five benzoxaboroles showed potent activity (50% effective concentration [EC50 ] < 5 μM) against intracellular amastigotes of at least one Leishmania species and acceptable activity (20 μM < EC50 < 30 μM) against two more species...
May 2018: Antimicrobial Agents and Chemotherapy
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