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https://www.readbyqxmd.com/read/28214219/perpetuating-stigma-or-reducing-risk-perspectives-from-naloxone-consumers-and-pharmacists-on-pharmacy-based-naloxone-in-2-states
#1
Traci C Green, Patricia Case, Haley Fiske, Janette Baird, Shachan Cabral, Dina Burstein, Victoriana Schwartz, Nathan Potter, Alexander Y Walley, Jeffrey Bratberg
OBJECTIVES: Little is known about attitudes of pharmacists and consumers to pharmacy naloxone. We examined perceptions and experiences of pharmacy naloxone from people with opioid use disorder, patients taking chronic opioids for pain, caregivers of opioid users, and pharmacists from 2 early pharmacy naloxone adopter states: Massachusetts and Rhode Island. DESIGN: Eight focus groups (4 per state) were held in October to December 2015. SETTING AND PARTICIPANTS: Participants were recruited from pharmacies, health clinics, and community organizations; pharmacists were recruited from professional organizations and pharmacy colleges...
February 14, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28210394/efficacy-and-safety-of-a-novel-100-silicone-scar-gel-treatment-for-early-intervention-in-scar-management
#2
David J Goldberg
Objective: To evaluate the efficacy and safety of a new topical silicone gel for the early intervention in the management of scars. Design: In this 12-week, observational study, healthy subjects (n=15) with an accessible linear or hypertrophic scar were given the test product and instructed to apply twice daily. Subjects returned 14, 28, 56, and 84 days later for evaluation and recording of adverse events. Setting: Private practice of the author. Participants: Eligible subjects had a scar with a Vancouver Scar Scale total score ≥3 at baseline...
December 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28209175/effectiveness-of-topical-silicone-gel-and-pressure-garment-therapy-for-burn-scar-prevention-and-management-in-children-study-protocol-for-a-randomised-controlled-trial
#3
Jodie Wiseman, Megan Simons, Roy Kimble, Robert Ware, Steven McPhail, Zephanie Tyack
BACKGROUND: Abnormal scar development following burn injury can cause substantial physical and psychological distress to children and their families. Common burn scar prevention and management techniques include silicone therapy, pressure garment therapy, or a combination of both. Currently, no definitive, high-quality evidence is available for the effectiveness of topical silicone gel or pressure garment therapy for the prevention and management of burn scars in the paediatric population...
February 16, 2017: Trials
https://www.readbyqxmd.com/read/28208898/to-study-the-efficacy-of-difluprednate-ophthalmic-emulsion-and-prednisolone-acetate-ophthalmic-suspension-on-post-operative-inflammation-in-cataract-surgery
#4
Punita Garg, Nupur Tuteja, Shazia Qayum
INTRODUCTION: Senile cataract is the most common cause of visual impairment. Removal of cataract and implantation of intraocular lens implantation (IOL) is the main surgical approach for cataract. The major block in quick visual rehabilitation of the patient is post-operative inflammation. To limit post-operative inflammation corticosteroids drugs are used in routine prophylactically. Topical prednisolone acetate 1% and betamethasone 0.1% remain gold standard to control post-operative inflammation but newer drugs like difluprednate, loteprednol are also effective in controlling inflammation...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28204733/a-randomized-trial-to-evaluate-the-effect-of-two-topical-anesthetics-on-pain-response-during-frenotomy-in-young-infants
#5
Itai Shavit, Yael Peri-Front, Anda Rosen-Walther, Ruth E Grunau, Gal Neuman, Omri Nachmani, Gideon Koren, Dror Aizenbud
No abstract text is available yet for this article.
February 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28204726/the-role-of-qutenza%C3%A2-topical-capsaicin-8-in-treating-neuropathic-pain-from-critical-ischemia-in-patients-with-end-stage-renal-disease-an-observational-cohort-study
#6
Emma Aitken, Gillian McColl, David Kingsmore
No abstract text is available yet for this article.
February 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28203195/27-gauge-vitrectomy-for-symptomatic-vitreous-floaters-with-topical-anesthesia
#7
Zhong Lin, Nived Moonasar, Rong Han Wu, Robin R Seemongal-Dass
PURPOSE: Traditionally acceptable methods of anesthesia for vitrectomy surgery are quite varied. However, each of these methods has its own potential for complications that can range from minor to severe. The surgery procedure of vitrectomy for symptomatic vitreous floaters is much simpler, mainly reflecting in the nonuse of sclera indentation, photocoagulation, and the apparently short surgery duration. The use of 27-gauge cannulae makes the puncture of the sclera minimally invasive...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28196712/ipomoea-pes-caprae-l-r-br-convolvulaceae-as-a-topical-herbal-medicine-to-relieve-pain-and-inflammation-promising-tool-against-effects-due-to-toxin-skin-contact
#8
Cristiane da Silva Barth, Hugo Guilherme Tolentino de Souza, Lilian W Rocha, Gislaine Francieli da Silva, Mariana Ferreira Dos Anjos, Veronica D'Avila Pastor, Tania Mari Belle Bresolin, Angelica Garcia Couto, José Roberto Santin, Nara Lins Meira Quintão
ETHNOPHARMACOLOGICAL RELEVANCE: Ipomoea pes-caprae is known as bayhops, beach morning glory or goat's foot, and in Brazil as salsa-de-praia. Its leaves are used in worldwide folk medicine for the relief of jellyfish-stings symptoms. The literature only reports the anti-inflammatory and neutralizing effects of a nonpolar plant derived, without validating the popular use or exploring the mechanism of action. AIM OF THE STUDY: This study aimed to evaluate and validate the topical effects of a semisolid containing hydroethanolic extract obtained from the aerial parts of I...
February 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28193100/corneal-antinociceptive-effect-of-%C3%AE-bisabolol
#9
Gisele Façanha Diógenes Teixeira, Flávio Nogueira da Costa, Adriana Rolim Campos
CONTEXT: (-)-α-Bisabolol (BISA) is a sesquiterpene alcohol widely used as scent in cosmetic preparations, perfumes, shampoos, toilet soaps and other toiletries with potential for use in the pharmaceutical area. OBJECTIVE: To evaluate the corneal antinociceptive efficacy of BISA and to analyze the best solubilizing agent. MATERIALS AND METHODS: Acute corneal nociception was induced by the local application of hypertonic saline (5 M NaCl; 20 μL) to the corneal surface of Swiss mice (n = 8/group) 60 min after topical treatment with solutions or ointment containing BISA (50-200 mg/mL)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28192733/prospective-long-term-results-complications-and-risk-factors-in-pelvic-organ-prolapse-treatment-with-vaginal-mesh
#10
Inés M Laso-García, Miguel A Rodríguez-Cabello, Miguel A Jiménez-Cidre, Andrea Orosa-Andrada, David Carracedo-Calvo, Luis López-Fando, Francisco J Burgos-Revilla
OBJECTIVE: To assess the long-term results and complications of pelvic organ prolapse treatment with transvaginal mesh. STUDY DESIGN: Prospective observational study of 75 women who underwent surgery between 2005 and 2008 by the same surgeon. 44 patients (58,7%) underwent concomitant treatment of stress urinary incontinence. Anatomical criterion for failure was prolapse grade >I in any compartment. Analysis of functional features consisted of an assessment of urinary, sexual, and defecation symptoms, and pelvic pain...
February 6, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28191793/lateral-decubitus-position-vs-lithotomy-position-which-is-the-best-way-to-minimize-patient-s-pain-perception-during-transrectal-prostate-biopsy
#11
Phil Hyun Song, Young Hwii Ko
INTRODUCTION: Considering the distinctive nature in terms of psychological stress and anal tone of position which is generally selected between lithotomy and left lateral decubitus (LLD), we postulated its effect on pain perception during biopsy, and investigated their association. MATERIALS AND METHODS: A prospective study for comparison of two biopsy positions which were perform in a different working day was conducted for 208 men (lithotomy position=86, LLD=122)...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28191496/lidocaine-spray-alone-is-similar-to-spray-plus-viscous-solution-for-pharyngeal-observation-during-transoral-endoscopy-a-clinical-randomized-trial
#12
Tomoyuki Hayashi, Yoshiro Asahina, Yohei Waseda, Kazuya Kitamura, Takashi Kagaya, Takuya Seike, Kazuhiro Okada, Yuki Inada, Hisashi Takabatake, Noriaki Orita, Yuko Yanase, Tatsuya Yamashita, Itasu Ninomiya, Kenichi Yoshimura, Shuichi Kaneko
Background and study aims It is important to examine the pharynx during upper gastrointestinal endoscopy. Pharyngeal anesthesia using topical lidocaine is generally used as pretreatment. In Japan, lidocaine viscous solution is the anesthetic of choice, but lidocaine spray is applied when the former is considered insufficient. However, the relationship between the extent of pharyngeal anesthesia and accuracy of observation is unclear. We compared the performance of lidocaine spray alone versus lidocaine spray combined with lidocaine viscous solution for pharyngeal observation during transoral endoscopy...
January 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28190463/prophylactic-topical-paeoniflorin-prevents-mechanical-allodynia-caused-by-paclitaxel-in-mice-through-adenosine-a1-receptors
#13
Tsugunobu Andoh, Nao Kobayashi, Daisuke Uta, Yasushi Kuraishi
BACKGROUND: The chemotherapeutic agent paclitaxel (PTX) causes refractory peripheral neuropathy as a side effect. Prophylactic oral administration of the traditional herbal medicine Shakuyakukanzoto containing Paeoniae Radix and Glycyrrhizae Radix prevents the development of PTX-induced mechanical allodynia in mice via peripheral effects, mostly due to Paeoniae Radix. However, the bioactive component responsible for the prevention of PTX-induced neuropathic pain remains unknown. PURPOSE: To determine whether a monoterpene glycoside paeoniflorin (PF), which is the principal bioactive constituent of Paeoniae Radix, has inhibitory effects on PTX-induced mechanical allodynia and investigate the underlying mechanisms...
February 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28186841/topical-treatments-for-acute-and-chronic-wound-pain-327
#14
Katherine Steele
No abstract text is available yet for this article.
February 10, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28174415/comparison-of-enoxaparin-and-rivaroxaban-in-balance-of-anti-fibrinolysis-and-anticoagulation-following-primary-total-knee-replacement-a-pilot-study
#15
Jinwei Xie, Jun Ma, Qiang Huang, Chen Yue, Fuxing Pei
BACKGROUND This study aimed to assess whether the efficacy of tranexamic acid (TXA) would be altered when rivaroxaban or enoxaparin was used for thromboprophylaxis in primary total knee replacement (TKR). It was hypothesized that the hemostatic effect of TXA would be better with the use of enoxaparin. MATERIAL AND METHODS A randomized clinical trial was conducted on 194 patients undergoing primary TKR for osteoarthritis. An intravenous dose of 15 mg/kg (TXA) and 1 g topical TXA were used. Patients randomly received enoxaparin or rivaroxaban prophylaxis when the drainage was less than 30 ml/h 6-8 h postoperatively...
February 8, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28171780/people-s-beliefs-about-the-meaning-of-crepitus-in-patellofemoral-pain-and-the-impact-of-these-beliefs-on-their-behaviour-a-qualitative-study
#16
Claire J Robertson, Michael Hurley, Fiona Jones
BACKGROUND: A feature of patellofemoral pain is joint crepitus. Several causes of crepitus have been described, but previous research has focused on the pathological meaning of crepitus. No research has demonstrated a definitive link between noise and pathology and its importance and meaning to patients is unresearched. OBJECTIVE: To explore the beliefs of patients with non-osteoarthritic patellofemoral pain regarding their crepitus, and how this impacts on their behaviour...
February 2, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28170093/topical-treatments-for-blepharokeratoconjunctivitis-in-children
#17
REVIEW
Michael O'Gallagher, Catey Bunce, Melanie Hingorani, Frank Larkin, Stephen Tuft, Annegret Dahlmann-Noor
BACKGROUND: Blepharokeratoconjunctivitis (BKC) is a type of inflammation of the surface of the eye and eyelids that involves changes of the eyelids, dysfunction of the meibomian glands, and inflammation of the conjunctiva and cornea. Chronic inflammation of the cornea can lead to scarring, vascularisation and opacity. BKC in children can cause significant symptoms including irritation, watering, photophobia and loss of vision from corneal opacity, refractive error or amblyopia.Treatment of BKC is directed towards modification of meibomian gland disease and the bacterial flora of lid margin and conjunctiva, and control of ocular surface inflammation...
February 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28167170/a-critical-overview-of-the-current-myofascial-pain-literature-january-2017
#18
REVIEW
Jan Dommerholt
Due to a change in the production schedule of this journal, two issues of this article were due within a month of each other, which precluded the usual group of authors from contributing to the current paper, but they will participate in this review in the next issue. This overview includes several articles questioning the use of dry needling (DN) by non-acupuncturists, which continues to be a controversial topic especially in the United States. Several researchers examined the effects of manual trigger point (TrP) techniques applied to TrPs in the upper trapezius muscle...
January 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28166710/latin-american-guidelines-for-opioid-use-in-chronic-nononcologic-pain
#19
Argelia Lara-Solares, Carlos Aguayo Zamora, César Amescua García, João Batista Santos Garcia, María Del Rosario Berenguel Cook, Patricia Bonilla Sierra, Durval Campos Kraychete, José Alberto Flores Cantisani, Carlos Guerrero, María Del Rocío Guillén Núñez, John Jairo Hernández Castro, Andrés Hernández Ortíz, Aziza Jreige Iskandar, Osvandré Lech, Jacqueline Macías Guerra, Gerardo Ramírez Samayoa, Edwin Rangel Morillo, María Antonieta Rico Pazos, Manuel Sempértegui Gallegos
AIM: Latin-American experts in the use of opioids in patients with chronic nononcologic pain (CNOP) have updated existing recommendations to current Latin-American reality. METHODS: Several key opinion leaders from Latin America participated in a face-to-face meeting in Guatemala (April 2015) to discuss the use of opioids in CNOP. Subgroups of experts worked on specific topics, reviewed the literature and shaped the final manuscript. RESULTS: The expert panel developed guidelines taking into consideration the utility of both opioid and nonopioid analgesics and factors pertaining to their efficacy, safety, adherence, administration and risks for abuse/addiction...
February 7, 2017: Pain Management
https://www.readbyqxmd.com/read/28166448/treatment-of-gingival-melanin-hyperpigmentation-with-er-cr-ysgg-laser-short-term-follow-up-of-patient
#20
Basak Kusakcİ Seker
The increasing melanin hyperpigmentation of dark skinned individuals was related to the high activity of melanocytes. Also smoking reactive the melanocytes to produce melanin. Gingival depigmentation is a periodontal plastic procedure which has been carried out by various techniques. A healthy 36-years-old female patient complained about unaesthetic gingiva and she had smoked over 17 years. Hyperpigmentation of gingiva observed on the labial surface of both maxilla and mandibula. Er,Cr:YSGG laser was used for depigmentation with wavelength of 2780nm, frequency of 20hz, and pulse energy between 0-300 Mj...
February 6, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
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