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Li Hua Jin

Hong-Yi Li, Hang Wang, Hai-Tiao Wang, Pei-Yong Xin, Xin-Hua Xu, Yun Ma, Wei-Ping Liu, Chang-Yun Teng, Cheng-Liang Jiang, Li-Ping Lou, Wyatt Arnold, Lauren Cralle, Yong-Guan Zhu, Jin-Fang Chu, Jack A Gilbert, Zhi-Jian Zhang
BACKGROUND: Paddy soil dissolved organic matter (DOM) represents a major hotspot for soil biogeochemistry, yet we know little about its chemodiversity let alone the microbial community that shapes it. Here, we leveraged ultrahigh-resolution mass spectrometry, amplicon, and metagenomic sequencing to characterize the molecular distribution of DOM and the taxonomic and functional microbial diversity in paddy soils across China. We hypothesized that variances in microbial community significantly associate with changes in soil DOM molecular composition...
October 19, 2018: Microbiome
Shuang Wu, Ye Zhou, Hai-Ying Hua, Yan Zhang, Wen-Yan Zhu, Zhi-Qing Wang, Jin Li, Hua-Qiang Gao, Xiao-Hong Wu, Ting-Xun Lu, Dong Hua
BACKGROUND: Systemic inflammation has been implicated in cancer development and progression. This study examined the best cutoff value of erythrocyte sedimentation rate (ESR) in diffuse large B-cell lymphoma (DLBCL) patients. METHODS: The relationship between ESR and clinical characteristics was analyzed in 182 DLBCL patients from 2006 to 2017. The log-rank test, univariate analysis, and Cox regression analysis were applied to evaluate the relationship between ESR and survival...
October 19, 2018: BMC Cancer
Yan-Yan Chen, Yu-Ping Tang, Er-Xin Shang, Zhen-Hua Zhu, Wei-Wei Tao, Jin-Gao Yu, Li-Mei Feng, Jie Yang, Jing Wang, Shu-Lan Su, Huiping Zhou, Jin-Ao Duan
ETHNOPHARMACOLOGICAL RELEVANCE: As recorded in traditional Chinese medicine (TCM) theory, Genkwa Flos (YH) and Glycyrrhizae Radix et Rhizoma (GC) compose one herbal pair of the so-called "eighteen incompatible medicaments", which indicate pairs of herbs that are mutually incompatible and that theoretically should not be applied simultaneously. However, the theory has been called into question due to a lack of evidence. AIMS OF STUDY: In this study, the incompatibility of YH and GC was investigated based on an assessment of the toxic effects of their combination by traditional safety methods and a modern metabonomic approach...
October 16, 2018: Journal of Ethnopharmacology
Xin-Yu Zhang, Jin-Hua Liang, Li Wang, Hua-Yuan Zhu, Wei Wu, Lei Cao, Lei Fan, Jian-Yong Li, Wei Xu
PURPOSE: This study was to compare DA-EPOCH-R and R-CHOP regimen as first-line therapy in diffuse large B cell lymphoma (DLBCL) patients, retrospectively. METHODS: A total of 252 cases treated with R-CHOP and 146 cases who received DA-EPOCH-R were enrolled into this study. RESULTS: Overall, 162 (64.3%) and 105 patients (71.9%) achieved complete remission, 43 (17.1%) and 14 patients (9.6%) achieved partial remission following R-CHOP and DA-EPOCH-R regimen, respectively...
October 16, 2018: Journal of Cancer Research and Clinical Oncology
Xiang Wei Gong, Jing Li, Hong Chi Ma, Guang Hua Chen, Meng Wang, Pu Yang, Jin Feng Gao, Bai Li Feng
Based on the ecological environment features of Loess Plateau, we examined field microclimate characteristics and yield of four different intercropping patterns for proso millet (P) and mung bean (M) including 2:2, 4:2, 4:4, 2:4. The results showed that, compared with monoculture, intercropping increased plant height, leaf area index (LAI) and chlorophyll content (SPAD) of proso millet in its late growth stage, while LAI and SPAD of mung bean decreased due to the shade of the high proso millet. Mung bean appeared spindly growth for a while by increasing the plant height...
October 2018: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
Jiong Dai, Yong-Ming Qiu, Zheng-Wen Ma, Guo-Feng Yan, Jing Zhou, Shan-Quan Li, Hui Wu, Yi-Chao Jin, Xiao-Hua Zhang
Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease. The aim of this study was to assess the efficacy of baicalin in a rat model of focal cerebral ischemia. Adult male Sprague-Dawley rat models of cerebral artery occlusion were established and then randomly and equally divided into three groups: ischemia (cerebral ischemia and reperfusion), valproic acid (cerebral ischemia and reperfusion + three intraperitoneal injections of valproic acid; positive control), and baicalin (cerebral ischemia and reperfusion + intraperitoneal injection of baicalin for 21 days)...
December 2018: Neural Regeneration Research
Xiaotong Sun, Hua Jin, Yangyang Li, Haiying Feng, Chunhong Liu, Jing Xu
This study aimed to investigate the variation of molecular functional properties of peanut protein isolate (PPI) over the storage process and reveal the correlation between the PPI secondary structure and properties in the storage procedure. After storage, the molecular properties of PPI changed significantly ( p < 0.05). Extending storage time resulted in a decrease in free sulfhydryl content, fluorescence intensity, surface hydrophobicity and emulsifying properties, which was accompanied by an increase in protein particle size...
October 12, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Jun-Hao Chen, Rui-Hua Zhang, Shao-Li Lin, Peng-Fei Li, Jing-Jing Lan, Sha-Sha Song, Ji-Ming Gao, Yu Wang, Zhi-Jing Xie, Fu-Chang Li, Shi-Jin Jiang
The duck hepatitis A virus type 1 (DHAV-1) is a member of Picornaviridae family, the genome of the virus contains a 5' untranslated region (5' UTR), a large open reading frame that encodes a polyprotein precursor and a 3' UTR followed by a poly(A) tail. The translation initiation of virus proteins depends on the internal ribosome-entry site (IRES) element within the 5' UTR. So far, little information is known about the role of the 3' UTR and poly(A) tail during the virus proliferation. In this study, the function of the 3' UTR and poly(A) tail of DHAV-1 in viral replication and IRES-mediated translation was investigated...
2018: Frontiers in Microbiology
Dong Ji, Guo-Feng Chen, Jin-Cheng Wang, Li-Hua Cao, Fengmin Lu, Xiao-Xin Mu, Xiao-Yu Zhang, Xiao-Jie Lu
The molecular mechanism of liver fibrosis caused by hepatitis C virus (HCV) is not clear. The aim of this study is to understand the molecular mechanism of liver fibrosis induced by HCV and to identify potential therapeutic targets for hepatic fibrosis. We analyzed gene expression patterns between high liver fibrosis and low liver fibrosis samples, and identified genes related to liver fibrosis. We identified TAF1, HNF4A, and CALM2 were related to the development of liver fibrosis. HNF4A is important for hepatic fibrogenesis, and upregulation of HNF4A is an ideal choice for treating liver fibrosis...
October 14, 2018: Journal of Cellular Physiology
Shao-Hua Xu, Wen Xu, Li Wang, Yi-Kao Hu, Jin-Ping Liu, Yan Zhao, Meng-Jia Li, Feng Li, Sheng-Xiong Huang, Yong Zhao
Five new phloroglucinol derivatives (1-5) together with one known analogue (6) were isolated from the leaves of Syzygium austroyunnanense which is an edible folk medicine used for the treatment of diabetes. The new structures were elucidated as austroyunones A - E (1-5) by means of the extensive spectroscopic analyses including high-resolution electrospray ionization mass spectrometry (HRESIMS) and 1D and 2D nuclear magnetic resonance (NMR). Compounds 4-6 showed obvious protein tyrosine phosphatase 1B (PTP1B) inhibitory activity...
October 10, 2018: Fitoterapia
Hua You, Xiao-Lu Li, Kang-Zhen Jing, Zhi-Guang Li, Hong-Mei Cao, Jin Wang, Lan Bai, Jing-Hong Gu, Xiaoman Fan, Hai Gu
BACKGROUND: This study aimed to explore the effects of (body mass index) BMI on health related quality of life (HRQoL) among the elderly in Jiangsu, China. METHODS: A total of 10,257 community dwelling elderly (≥60 years old) were enrolled in a cross-sectional study. HRQoL was measured via the Eq-5d-3 L. Chi-square tests and one-way ANOVA analyses were used to compare the frequencies and scores of Eq-5d responses among different BMI groups (defined as "underweight", "normal weight", "overweight" and "obese")...
October 12, 2018: BMC Public Health
Liye Xu, Jin Cheng Song, Xiu Hua Sun, Zi Fen Gao, Li Lv, Jie Zhu
RATIONALE: Central nervous system (CNS) infiltration of Richter's syndrome (RS) is rare and only a few cases were discussed. Of these published cases, either they were accompanied with lymph node involvement or with a history of chronic lymphocytic leukemia (CLL). To our knowledge, this is the first published case of RS of the brain and meninges diagnosed concurrently with CLL in the absence of any evidence of lymphoma outside of the CNS. PATIENT CONCERNS: A 67-year-old female presented with slurred speech, headache, and left-sided hemiparesis...
October 2018: Medicine (Baltimore)
Yong-Bao Chu, Min Li, Jin-Wei Liu, Wei Xu, Shi-Han Cheng, Hua-Zhang Zhao
Types and structures of phosphorus compounds influence the removal of phosphorus by coagulation. Until now, the molecular-level interaction between coagulants and phosphorus (especially organophosphates) and the relationship between removal efficiency and phosphorus structure have not been clear. This work investigated the removal of phosphorus with different structures using conventional coagulants (poly aluminum chloride (PACl) and polymerized ferric sulfate (PFS)) and a novel covalently-bound inorganic-organic hybrid coagulant (CBHyC)...
October 5, 2018: Water Research
Tong Liu, Wen-Qiang Yang, Yu-Gu Xie, Pei-Wen Liu, Li-Hua Xie, Feng Lin, Chen-Ying Li, Jin-Bao Gu, Kun Wu, Gui-Yun Yan, Xiao-Guang Chen
Aedes (Stegomyia) albopictus, also known as the Asian tiger mosquito, is a mosquito that originated in Asia. In recent years, it has become increasingly rampant throughout the world. This mosquito can transmit several arboviruses, including dengue, Zika and chikungunya viruses, and is considered a public health threat. Despite the urgent need of genome-engineering to analyse specific gene functions, progress in genetical manipulation of Ae. albopictus has been slow due a lack of efficient methods and genetic markers...
October 11, 2018: Insect Science
Jin Zhang, Ruifei Li, Xiaoying Zhang, Yun Bai, Pan Cao, Pei Hua
This study focuses on the source apportionments of polycyclic aromatic hydrocarbons (PAHs) in road dust (RD) with four size fractions through three receptor models of principal component analysis with multiple linear regression (PCA-MLR), positive matrix factorization (PMF) and Unmix. The concentrations of total PAHs range from 0.45 to 2.03μgg-1 . Results show that the concentrations of PAHs increased with a decreasing size fraction. Similar potential sources to PAHs in RD were extracted by three models with a little difference in numbers and percent load contributions of each identified sources...
February 1, 2019: Science of the Total Environment
Ming-Bing Xiao, Dan-Dan Jin, Yu-Jie Jiao, Wen-Kai Ni, Jin-Xia Liu, Li-Shuai Qu, Cui-Hua Lu, Run-Zhou Ni, Feng Jiang, Wei-Chang Chen
Psychological stress has been recognized as a well-documented risk factor associated with β2-adrenergic receptor (β2-AR) in the development of pancreatic cancer. Aldo-keto reductase 1 member B1 (AKR1B1) is a potential interacting partner of β2-AR, but the effect of their interaction on pancreatic cancer cells is not known at present. We found a positive correlation between AKR1B1 and β2-AR expression in pancreatic cancer tissue samples, and co-localization of these proteins in the human pancreatic cancer BXPC-3 cell line...
October 10, 2018: Molecular Biology Reports
Jing Pan, Yu-Qin Di, Yong-Bo Li, Cai-Hua Chen, Jin-Xing Wang, Xiao-Fan Zhao
Insulin promotes larval growth of insects by stimulating the synthesis of the steroid hormone 20-hydroxyecdysone (20E), which induces pupation and apoptosis. However, the mechanism underlying the coordinate regulation of insect pupation and apoptosis by these two functionally opposing hormones is still unclear. Here, using the lepidopteran insect and serious agricultural pest Helicoverpa armigera (cotton bollworm) as a model, we report that phosphoinositide-dependent kinase-1 (PDK1) and forkhead box O (FoxO) play key roles in these processes...
October 10, 2018: Journal of Biological Chemistry
Yue-Feng Wen, Tian-Tian Cheng, Xiao-Long Chen, Wen-Jin Huang, Hai-Hua Peng, Tong-Chong Zhou, Xiao-Dan Lin, Li-Si Zeng
OBJECTIVE: To evaluate the prognostic effects of combining serum circulating tumor cells (CTCs) and squamous cell carcinoma antigen (SCC-Ag) levels on patients with locally advanced cervical cancer treated with radiotherapy. METHODS: Ninety-nine patients with locally advanced cervical cancer ([FIGO] stage IIB-IVA) undergoing radiotherapy (RT) or concurrent chemoradiotherapy (CCRT) were identified. The association between serum CTC level and clinicopathological parameters was examined...
2018: PloS One
Li-Li Chen, Hong Li, Xiao-Huan Chen, Shuang Jin, Qiu-Hua Chen, Mei-Rong Chen, Na Li
We aim to investigate whether a popular hand exercise could be used to improve the action of eating in patients with Alzheimer's disease (AD). A 6-month intervention was conducted in 60 patients with AD who live in a nursing home. They were divided into hand exercise and control groups. Patients of the control group maintained their daily routine. The improvement of Edinburgh Feeding Evaluation in Dementia scale in hand exercise group was significantly greater than in the control group ( P = .003). Significant differences in time of autonomous eating and time of simulated eating between patients in the hand exercise and control groups ( P < ...
October 9, 2018: American Journal of Alzheimer's Disease and Other Dementias
Chao Zhu, Yu Chen, Fucai Liu, Shoujun Zheng, Xiaobao Li, Apoorva Chaturvedi, Jiadong Zhou, Qundong Fu, Yongmin He, Qingsheng Zeng, Hong Jin Fan, Hua Zhang, Wen-Jun Liu, Ting Yu, Zheng Liu
External stimuli-controlled phase transitions are essential for fundamental physics and design of functional devices. Charge density wave (CDW) is a metastable collective electronic phase featured by the periodic lattice distortion. Much attention has been attracted to study the external control of CDW phases. Although much work has been done in the electric-field-induced CDW transition, the study of the role of Joule heating in the phase transition is insufficient. Here, using the Raman spectroscopy, the electric-field-driven phase transition is in situ observed in the ultrathin 1T-TaS2 ...
October 9, 2018: ACS Nano
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