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Sergio Barros-Gomes, Abdullah El Sabbagh, Mackram F Eleid, Sunil V Mankad
Non-atherosclerotic myocardial infarction (MI) is an important but often misdiagnosed cause of acute MI. Furthermore, non-atherosclerotic MI with concomitant acute stroke and pulmonary embolism due to in-transit thrombus across a patent foramen ovale (PFO) is a rare but potentially fatal combination (1-3). Early detection of this clinical entity can facilitate delivery of targeted therapies and avoid poor outcome (1, 2). Here, we describe a 68-year-old female with hypertension, tobacco abuse, and chronic obstructive pulmonary disease presenting with facial droop, right arm weakness and aphasia...
August 11, 2018: Echo Research and Practice
Adrien Kaladji, Alexandre Villena, Remy Pascot, Florent Lalys, Anne Daoudal, Elodie Clochard, Antoine Lucas, Alain Cardon
INTRODUCTION: Fusion imaging is a technique that facilitates endovascular navigation but is only available in hybrid rooms. The goal of this study was to evaluate the feasibility of fusion imaging with a mobile C-arm in a conventional operating room through the use of an angio-navigation station. METHODS: From May 2016 to June 2017, the study included all patients who underwent an aortic stent graft procedure in a conventional operating room with a mobile flat-panel detector (Cios Alpha, Siemens) connected to an angio-navigation station (EndoNaut, Therenva)...
August 6, 2018: Annals of Vascular Surgery
Matthew C Shake, K Jason Crandall, Rilee P Mathews, Dustin G Falls, A Kathryn Dispennette
OBJECTIVE: A significant barrier to improving the health and well-being of older adults is that they often do not adhere to health-promoting programs. The present study examined whether Bingocize® , a game-centered mobile app that can combine bingo with healthy activities such as exercise and/or health topic education, could (1) engender high rates of adherence among sedentary community-dwelling older adults, and (2) potentially improve aspects of physical and cognitive performance. MATERIALS AND METHODS: Participants used the app for ∼1 hour, twice per week, for 10 weeks...
August 8, 2018: Games for Health
Sandra C Fuchs, Erno Harzheim, Cirano Iochpe, Caroline N de David, Marcelo R Gonçalves, Guilhermo P Sesin, Cassio M Costa, Leila B Moreira, Flavio D Fuchs
BACKGROUND: Hypertension is a growing problem worldwide, markedly in low- and middle-income countries, where the rate of control slightly decreased. The overall prevalence of hypertension in Brazil is 28.7% among adult individuals and 68.9% in the population aged 60 years and older, and less than a third of patients have controlled blood pressure (BP). The use of technologies-mobile phones and the internet-to implement interventions to reduce blood pressure can minimize costs and diminish cardiovascular risk...
August 7, 2018: JMIR Research Protocols
Cassandra Wright, Paul M Dietze, Paul A Agius, Emmanuel Kuntsche, Michael Livingston, Oliver C Black, Robin Room, Margaret Hellard, Megan Sc Lim
BACKGROUND: Real-time ecological momentary interventions have shown promising effects in domains other than alcohol use; however, only few studies regarding ecological momentary interventions for alcohol use have been conducted thus far. The increasing popularity of smartphones offers new avenues for intervention and innovation in data collection. OBJECTIVE: We aimed to test the efficacy of an ecological momentary intervention, comprising mobile Web-based ecological momentary assessments (EMAs) and text messaging (short message service, SMS) brief interventions, delivered during drinking events using participants' mobile phones...
July 20, 2018: JMIR MHealth and UHealth
Kelechi R Okoroha, Jason E Meldau, Vincent A Lizzio, Fabien Meta, Jeffrey P Stephens, Vasilious Moutzouros, Eric C Makhni
BACKGROUND: The incidence of overuse injury to the elbow among baseball pitchers continues to rise, despite extensive efforts at pitch count regulations and emphasis on proper throwing mechanics. PURPOSE: To determine if the medial elbow experiences increased torque levels as a baseball pitcher fatigues through the course of a simulated game. STUDY DESIGN: Descriptive laboratory study. METHODS: High school and collegiate baseball pitchers were recruited for this simulated game study...
August 2018: American Journal of Sports Medicine
Peter H Richter, Florian Gebhard, Alexander Eickhoff, Konrad Schütze
The invention of flat-panel detectors led to a revolution in medical imaging. The major benefits of this technology are a higher image quality and dose reduction. Flat-panel detectors have proved to be superior to standard C-arms (= C-arm with radiograph source and image intensifier).Cone-beam computed tomography (cone-beam CT) is a 3D data set, which can be acquired with a flat-panel detector. The cone-shaped beam is used for 3D data generation. For cone-beam CT acquisition, the flat-panel detector rotates around the patient lying on the operating table...
May 2018: EFORT Open Reviews
Thu H M Nguyen, Patricia E Carreira, Francisco J Sanchez-Luque, Stephanie N Schauer, Allister C Fagg, Sandra R Richardson, Claire M Davies, J Samuel Jesuadian, Marie-Jeanne H C Kempen, Robin-Lee Troskie, Cini James, Elizabeth A Beaven, Tristan P Wallis, Jermaine I G Coward, Naven P Chetty, Alexander J Crandon, Deon J Venter, Jane E Armes, Lewis C Perrin, John D Hooper, Adam D Ewing, Kyle R Upton, Geoffrey J Faulkner
LINE-1 (L1) retrotransposons are a source of insertional mutagenesis in tumor cells. However, the clinical significance of L1 mobilization during tumorigenesis remains unclear. Here, we applied retrotransposon capture sequencing (RC-seq) to multiple single-cell clones isolated from five ovarian cancer cell lines and HeLa cells and detected endogenous L1 retrotransposition in vitro. We then applied RC-seq to ovarian tumor and matched blood samples from 19 patients and identified 88 tumor-specific L1 insertions...
June 26, 2018: Cell Reports
Rohan C Siriwardana, Sumudu K Kumarage, Bhagya M Gunathilake, Suchintha B Thilakarathne, Jeevani S Wijesinghe
BACKGROUND: Transverse abdominal plane block (TAP) is a new technique of regional block described to reduce postoperative pain in laparoscopic cholecystectomy (LC). Recent reports describe an easy technique to deliver local anesthetic agent under laparoscopic guidance. METHODS: This randomized control trial was designed to compare the effectiveness of additional laparoscopic-guided TAP block against the standard full thickness port site infiltration. 45 patients were randomized in to each arm after excluding emergency LC, conversions, ones with coagulopathy, pregnancy and allergy to local anesthetics...
June 25, 2018: Surgical Endoscopy
A C Berry
Tremendous advancements in syndromic surveillance strategies over the last two decades, and specifically from prior mass gatherings, have been incorporated into day-to-day healthcare analysis worldwide and have left a lasting indirect impact since their inception. Mass gatherings are a daily occurrence worldwide and provide a scenario ripe for public health aims and objectives utilising syndromic surveillance. Europe is less than a decade away from hosting a colossal worldwide gathering (2024 Summer Olympics) in likely a time when the global agreement is in flux...
June 22, 2018: Epidemiology and Infection
Mirko Tessari, Veronica Tisato, Erika Rimondi, Paolo Zamboni, Anna Maria Malagoni
OBJECTIVE: We aimed to evaluate the effects of intermittent pneumatic compression (IPC) in patients at low mobility with leg edema. METHODS: A pilot, two-arm, randomized controlled clinical trial was performed. Fifty patients (age, 58.4 ± 9 years; male, 14), randomly allocated to a group (IPC) undergoing 1 month (n = 29) of an in-home cycle of IPC and to a control (C) group (n = 21), were studied. Leg edema was evaluated by measuring subcutaneous thickness (high-resolution ultrasound) and circumferences (metric tape), both assessed at different levels of the lower limbs, and volume (water plethysmography)...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
C M Bauer, F M Rast, C Böck, R P Kuster, D Baumgartner
OBJECTIVE: This study investigated the location of the axis of rotation in sagittal plane movement of the spine in a free sitting condition to adjust the kinematics of a mobile seat for a dynamic chair. BACKGROUND: Dynamic office chairs are designed to avoid continuous isometric muscle activity, and to facilitate increased mobility of the back during sitting. However, these chairs incorporate increased upper body movement which could distract office workers from the performance of their tasks...
October 2018: Applied Ergonomics
Alberto Mangano, Federico Gheza, Roberto Bustos, Mario Masrur, Francesco Bianco, Eduardo Fernandes, Valentina Valle, Pier C Giulianotti
BACKGROUND: Minimally invasive surgery (MIS) approaches have produces relevant advancements in the pre/intra/post-operative outcomes. The conventional laparoscopic approach presents similar oncological results in comparison to laparotomic approaches. Despite these evidences, a considerable part of the colorectal operations are still being performed in an open way. This is in part because traditional laparoscopy may have some hurdles and a long learning curve to reach mastery. The robotic technology may help in increasing the MIS penetrance in colorectal surgery...
May 31, 2018: Minerva Chirurgica
Blandine Maurel, Teresa Martin-Gonzalez, Debra Chong, Andrew Irwin, Guillaume Guimbretière, Meryl Davis, Tara M Mastracci
OBJECTIVE: Use of three-dimensional fusion has been shown to significantly reduce radiation exposure and contrast material use in complex (fenestrated and branched) endovascular aneurysm repair (EVAR). Cydar software (CYDAR Medical, Cambridge, United Kingdom) is a cloud-based technology that can provide imaging guidance by overlaying preoperative three-dimensional vessel anatomy from computed tomography scans onto live fluoroscopy images both in hybrid operating rooms and on mobile C-arms...
May 24, 2018: Journal of Vascular Surgery
Brian C Clark, David W Russ, Masato Nakazawa, Christopher R France, Stevan Walkowski, Timothy D Law, Megan Applegate, Niladri Mahato, Samuel Lietkam, James Odenthal, Daniel Corcos, Simeon Hain, Betty Sindelar, Robert J Ploutz-Snyder, James S Thomas
BACKGROUND: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully understood. Herein, we present the study protocol for The Researching the Effectiveness of Lumbar Interventions for Enhancing Function Study (The RELIEF Study). METHODS AND STUDY DESIGN: The RELIEF Study is a Phase II RCT with a nested mechanistic design...
July 2018: Contemporary Clinical Trials
Mahmut Kalem, Kerem Başarır, Hakan Kocaoğlu, Ercan Şahin, Hakan Kınık
Objectives: To examine the effect of fluoroscopy devices with different sizes of image intensifier and C-arm maneuverability on operating time, fluoroscopy time, radiation dose and reduction, and fixation quality at intertrochanteric femoral fractures. Design: Single-center, randomized, prospective study. Setting: Academic Level I trauma hospital. Patients and Intervention: 34 patients treated with cephalomedullary nailing for a stable, intertrochanteric proximal femur fracture (OTA A1)...
2018: BioMed Research International
Benjamin C Riordan, Saleh Moradi, Kate B Carey, Tamlin S Conner, Kyungho Jang, Kelly E Reid, Damian Scarf
BACKGROUND: Alcohol use among university students is common, and those who drink often choose to drink heavily (ie, 4 or more drinks per session for women or 5 or more for men). Web-based interventions (WBIs), in which students complete assessments and receive personalized feedback about their alcohol use, and ecological momentary interventions (EMIs), which use mobile devices as a method of delivering intervention information, are 2 methods that have had some success in reducing alcohol use among university students...
May 15, 2018: JMIR Research Protocols
Kelechi R Okoroha, Vincent A Lizzio, Fabien Meta, Christopher S Ahmad, Vasilios Moutzouros, Eric C Makhni
BACKGROUND: There has been an increasing incidence of overuse elbow injuries among youth and adolescent pitchers. Pitch type has been implicated as a risk factor for excess torque at the medial elbow; however, this has not been definitively demonstrated. PURPOSE: To assess predictors of torque across the medial elbow in youth and adolescent pitchers with a mobile sensor. In addition, the authors aimed to determine the differences in elbow torque produced according to pitch type (fastball, curveball, changeup) and pitcher demographics...
July 2018: American Journal of Sports Medicine
Carinne Brody, Sovannary Tuot, Pheak Chhoun, Dallas Swendenman, Kathryn C Kaplan, Siyan Yi
BACKGROUND: In Cambodia, HIV prevalence is concentrated in key populations including among female entertainment workers (FEWs) who may engage in direct or indirect sex work. Reaching FEWs with sexual and reproductive health (SRH) services has been difficult because of their hidden and stigmatized nature. Mobile-phone-based interventions may be an effective way to reach this population and connect them with the existing services. This article describes study design and implementation of a randomized controlled trial (RCT) of a mobile health intervention (the Mobile Link) aiming to improve SRH and related outcomes among FEWs in Cambodia...
April 19, 2018: Trials
Prem K Mony, Prashanth Thankachan, Swarnarekha Bhat, Suman Rao, Maryann Washington, Sumi Antony, Annamma Thomas, Sheela C Nagarajarao, Hiteshwar Rao, Bharadwaj Amrutur
Objective: Newer technologies such as wearables, sensors, mobile telephony and computing offer opportunities to monitor vital physiological parameters and tackle healthcare problems, thereby improving access and quality of care. We describe the design, development and testing of a wearable sensor device for remote biomonitoring of body temperatures in mothers and newborns in southern India. Methods: Based on client needs and technological requirements, a wearable sensor device was designed and developed using principles of 'social innovation' design...
April 2018: BMJ Innovations
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