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hybrid operating room

Karen Ven, Saba Safdar, Annelies Dillen, Jeroen Lammertyn, Dragana Spasic
DNA- and MNAzymes are nucleic acid-based enzymes (NAzymes), which infiltrated the otherwise protein-rich field of enzymology three decades ago. The 10-23 core NAzymes are one of the most widely used and well-characterized NAzymes, but often require elevated working temperatures or additional complex modifications for implementation at standard room temperatures. Here, we present a generally applicable method, based on thermodynamic principles governing hybridization, to re-engineer the existing 10-23 core NAzymes for use at 23 °C...
October 20, 2018: Analytical and Bioanalytical Chemistry
Kazumasa Orihashi
Transesophageal echocardiography (TEE) provides real-time information on both morphology and hemodynamics without radiation exposure or contrast media, interruption of surgical procedures, or need for transferring the patient to other division, and thus can be used as intraoperative monitoring as well as diagnostic imaging. TEE is helpful for confirming the adequacy of routine surgical procedures, ruling out an occurrence of unexpected adverse events, or even navigating the manipulations of cannulae and catheters...
September 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Yin-Kai Chao, Hsin-Yueh Fang, Yu-Wen Wen, Ming-Ju Hsieh, Chih-Tsung Wen
OBJECTIVES: With the increasing availability of hybrid operating rooms, single-stage tumour localization and removal under intraoperative computed tomography (CT) guidance is gaining popularity. The objective of this study was to describe the learning curve for this procedure. METHODS: Over a 15-month period, a single team of thoracic surgeons without experience in intraoperative CT-guided lung tumour localization performed a total of 91 procedures in 89 patients...
October 5, 2018: European Journal of Cardio-thoracic Surgery
Xianzeng Tong, Peng Hu, Guilin Li, Hongqi Zhang
No abstract text is available yet for this article.
October 2, 2018: Journal of Neurosurgical Sciences
Francesco Maddalena, Xin Yu Chin, Daniele Cortecchia, Annalisa Bruno, Cesare Soci
Perovskite light-emitting field-effect transistors (PeLEFETs) provide a versatile device architecture to control transport and electroluminescence properties of hybrid perovskites, enabling injection of high charge carrier density and spatial control of the radiative recombination zone. Ionic screening and organic cation polarization effects typical of metal-halide perovskites, however, critically affect PeLEFET efficiency and reliability. In this work, we demonstrate a new device operation mode based on high-frequency modulation of the applied voltages, which allows significant reduction of ionic drift/screening in methylammonium lead iodide light-emitting transistors...
October 18, 2018: ACS Applied Materials & Interfaces
Dan Loberman, Shahzad Shaefi, Rephael Mohr, Phillip Dombrowski, Richard B Zelman, Yifan Zheng, Paul A Pirundini, Tomer Ziv-Baran
Symptomatic aortic stenosis remains a surgical disease, with aortic valve replacement resulting in symptom reduction and improvement in survival. For patients who are deemed a higher surgical risk, Transcatheter aortic-valve replacement (TAVR) is a viable, less invasive and increasingly common alternative. The study compares early outcomes in patients treated within one year of the commencement of TAVR program in a community hospital against outcomes of TAVR patients from nationwide reported data (Society of Thoracic Surgeons/ American College of Cardiology TVT registry)...
2018: PloS One
Colin D Rawlings, Yu Kyoung Ryu, Matthieu Rüegg, Nolan Lassaline, Christian Schwemmer, Urs Duerig, Armin Knoll, Zahid Ali Khan Durrani, Chen Wang, Dixi Liu, Mervyn E Jones
The fabrication of high-performance solid-state silicon quantum-devices requires high resolution patterning with minimal substrate damage. We have fabricated room temperature single-electron transistors (SETs) based on point-contact tunnel junctions using a hybrid lithography tool capable of both high resolution thermal scanning probe lithography and high throughput direct laser writing. The best focal z-position and the offset of the tip- and the laser-writing positions were determined in-situ with the scanning probe...
September 24, 2018: Nanotechnology
Dongting Wang, Shangheng Liu, Mingfa Shao, Jinghan Zhao, Yukun Gu, Qiuyi Li, Xianxi Zhang, Jinsheng Zhao, Yuzhen Fang
Hierarchical SnO₂ nanocrystallites aggregates (NAs) were prepared with a simple room temperature⁻based aqueous solution method followed by simple freeze-drying treatment. The as-prepared SnO₂ NAs were subsequently combined with SnO₂ nanosheet⁻based structures from the viewpoint of a function-matching strategy, and under an optimized condition, a power conversion efficiency (PCE) of 5.59% was obtained for the resultant hybrid photoanode, a remarkable 60% enhancement compared to that of dye-sensitized solar cells (DSCs) fabricated with bare SnO₂ NAs architecture...
September 19, 2018: Materials
Adrian Elmi Terander, Gustav Burström, Rami Nachabe, Halldor Skulason, Kyrre Pedersen, Michael Fagerlund, Fredrik Ståhl, Anastasios Charalampidis, Michael Söderman, Staffan Holmin, Drazenko Babic, Inge Jenniskens, Erik Edström, Paul Gerdhem
STUDY DESIGN: Prospective observational study. OBJECTIVE: The aim of this study was to evaluate the accuracy of pedicle screw placement using augmented reality surgical navigation in a clinical trial. SUMMARY OF BACKGROUND DATA: Recent cadaveric studies have shown improved accuracy for pedicle screw placement in the thoracic spine using augmented reality surgical navigation with intraoperative 3D imaging, without the need for peri-procedural X-ray...
September 17, 2018: Spine
Vijaya T Daniel, Didem Ayturk, Catarina I Kiefe, Heena P Santry
BACKGROUND: Acute care surgery (ACS) was proposed to address a general surgery workforce crisis; however, the ACS workforce composition is unknown. A national survey was conducted to determine the differences in the emergency general surgery (EGS) workforce between ACS and non-ACS hospitals. METHODS: The American Hospital Association (AHA) Annual Survey of Hospitals database was queried to identify acute care general hospitals. A hybrid mail/electronic survey was sent to 2811 acute care hospitals that met the inclusion criteria of hospitals that care for adult patients (≥18 years old) with an emergency room (ER), ≥ 1 operating room (OR), and 24-h ER access...
September 8, 2018: American Journal of Surgery
Hiroaki Watanabe, Yoshihide Shimojo, Eiji Hira, Shunsuke Kuramoto, Tomohiro Muronoi, Kazuyuki Oka, Akihiko Kidani
The hybrid emergency room (hybrid ER) system was first established in 2011 in Japan. It is defined as an integrated system including an ER, emergency computed tomography (CT) and interventional radiology (IVR) rooms, and operating rooms. Severe trauma patients can undergo emergency CT examinations and therapies (surgeries) without being transferred. The hybrid ER system is attracting attention because trauma resuscitation using this system has been reported to potentially improve the mortality rate in severe trauma patients...
September 17, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Pei-Hsing Chen, Hsao-Hsun Hsu, Shun-Mao Yang, Tung-Ming Tsai, Kuan-Chuan Tsou, Hsien-Chi Liao, Mong-Wei Lin, Jin-Shing Chen
BACKGROUND: Preoperative computed tomography (CT)-guided dye localization is essential for the surgical treatment of small lung nodules and is mostly performed by radiologists in the CT room. Several studies reported their early experiences of preoperative localization in the hybrid operating room. A comparison between localization in the CT and hybrid rooms has not been reported. Therefore, we compared the outcomes of preoperative localization in the hybrid and CT rooms. METHODS: This study included patients who underwent preoperative CT-guided dye localization for thoracoscopic lung tumor surgery in the hybrid operation (n=25) and CT (n=283) rooms at our institute...
September 12, 2018: Annals of Thoracic Surgery
Basil E Grüter, Fabio Strange, Felice Burn, Luca Remonda, Michael Diepers, Javier Fandino, Serge Marbacher
OBJECTIVE: Dural arteriovenous fistulas (dAVFs) are abnormal direct shunts between the occipital or meningeal artery and a meningeal vein or dural venous sinus. Treatment strategies include endovascular, microsurgical, stereotactic radiosurgical, or combined interventions. With few previous reports focused on dAVF treatment in a hybrid operating room (hOR), the authors reviewed their 6-year experience in this unique setting for these complex fistulas. METHODS: Patients with complex cerebral dAVFs underwent endovascular and microsurgical treatment in the hOR...
September 3, 2018: World Neurosurgery
Kailing Li, Yunbao Guo, Limei Qu, Baofeng Xu, Kan Xu, Jinlu Yu
An accessory middle cerebral artery (AMCA), which mainly acts in the collateral circulation of the middle cerebral artery (MCA), is a rare anatomic malformation. Similar to other intracranial vessels, cerebrovascular disease can occur in the AMCA. However, the development of an arteriovenous malformation (AVM) in the AMCA is very rare, especially in conjuction with developmental venous anomalies (DVAs). Here, a rare case of an AMCA combined with an AVM and a DVA was reported. The patient was a 47-year-old female with intracranial hemorrhage at symptom onset...
September 2018: Experimental and Therapeutic Medicine
Vincenzo Vento, Raphael Soler, Dominique Fabre, Laurence Gavit, Emmanuelle Majus, Philippe Brenot, Mauro Gargiulo, Stéphan Haulon
Improvements in endovascular technologies and development of custom-made fenestrated and branched endografts currently allow clinicians to treat complex aortic lesions such as thoraco-abdominal and aortic arch aneurysms once treatable with open repair only. These advances are leading to an increase in the complexity of endovascular procedures which can cause long operation times and high levels of radiation exposure. This in turn places pressure on the vascular surgery community to display more superior interventional skills and radiological practices...
August 28, 2018: Journal of Cardiovascular Surgery
Marina Rumyantseva, Abulkosim Nasriddinov, Svetlana Vladimirova, Sergey Tokarev, Olga Fedorova, Ivan Krylov, Konstantin Drozdov, Alexander Baranchikov, Alexander Gaskov
In this work, the hybrids based on nanocrystalline SnO₂ or In₂O₃ semiconductor matrixes and heterocyclic Ru(II) complex are studied as materials for gas sensors operating at room temperature under photoactivation with visible light. Nanocrystalline semiconductor oxides are obtained by chemical precipitation with subsequent thermal annealing and characterized by XRD, SEM and single-point BET methods. The heterocyclic Ru(II) complex is synthesized for the first time and investigated by ¹H NMR, 13 C NMR APT, MALDI-MS analysis, and UV-Vis spectroscopy...
August 29, 2018: Nanomaterials
Maged Argalious, Carlos Trombetta, Natalya Makarova, Wael Saasouh, Shobana Rajan
OBJECTIVE: Cerebrospinal fluid drainage catheter-related complications can be reduced by following strict guidelines during their introduction, maintenance, and removal. The authors therefore aimed to determine whether simulation-based learning would improve senior anesthesiology residents' patient care performance during the insertion and management of these catheters compared to interactive problem-based learning (PBL) using the Anaesthetists' Non-Technical Skills global rating scale (ANTS)...
July 25, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Sanjay Konakondla, Christoph J Griessenauer, Reginald P Fong, Oded Goren, Clemens M Schirmer
The hybrid operating room (OR) offers new opportunities for the management of complex cerebrovascular lesions to the dual trained neurovascular surgeon. It creates a space for easy accessibility to perform complex endovascular procedures by delivering high quality images with readily available surgical equipment. Here, we demonstrate how the hybrid OR allowed for rapid identification and near zero-delay distal mechanical thrombectomy of a middle cerebral artery occlusion with favorable outcome after clipping of a complex posterior communicating artery aneurysm...
August 22, 2018: World Neurosurgery
H-Y Tan, J Yang, Z-Y Wang, W-D Zhu, Y-C Chai, H Jia, H Wu
OBJECTIVE: To examine the impact of integrated hybrid operating rooms for endoscope-assisted microsurgery using the presigmoid retrolabyrinthine (RL) approach, and to determine the value of simultaneous supervision of skull base endoscopic procedures by microscope. MATERIAL AND METHODS: We retrospectively reviewed endoscope-assisted surgery using the RL approach at our institution between September 2013 and January 2017. The simultaneous supervision of endoscopic procedures by microscope was realized using the integrated hybrid system...
August 20, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
Yin-Kai Chao, Kuang-Tse Pan, Chih-Tsung Wen, Hsin-Yueh Fang, Ming-Ju Hsieh
BACKGROUND: The efficacy and safety of intraoperative computed tomography (IOCT)-guided lung tumor localization and resection performed in a hybrid operating room (OR) compared with the conventional 2-stage preoperative CT (POCT)-guided approach for the treatment of small and deep solitary pulmonary nodules (SPNs) remains unknown. METHODS: We compared IOCT-guided (IOCT group) and POCT-guided (POCT group) thoracoscopic resections in 64 consecutive patients with SPNs...
July 20, 2018: Journal of Thoracic and Cardiovascular Surgery
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