Victoria Fitz, Sandro Graca, Shruthi Mahalingaiah, Jing Liu, Lily Lai, Ali Butt, Mike Armour, Vibhuti Rao, Dhevaksha Naidoo, Alison Maunder, Guoyan Yang, Vaishnavi Vaddiparthi, Selma F Witchel, Alexia Pena, Poli Mara Spritzer, Rong Li, Chau Tay, Aya Mousa, Helena Teede, Carolyn Ee
CONTEXT: Insulin resistance is common in women with Polycystic Ovary Syndrome (PCOS). Inositol may have insulin sensitising effects; however, its efficacy in the management of PCOS remains indeterminate. OBJECTIVE: To inform the 2023 International Evidence-based Guidelines in PCOS, this systematic review and meta-analysis evaluated the efficacy of inositol, alone or in combination with other therapies, in the management of PCOS. DATA SOURCES: Medline, PsycInfo, EMBASE, All EBM, and CINAHL from inception until August 2022...
January 2, 2024: Journal of Clinical Endocrinology and Metabolism