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https://www.readbyqxmd.com/read/28652925/effect-of-feeding-garlic-leaves-on-rumen-fermentation-methane-emission-plasma-glucose-kinetics-and-nitrogen-utilization-in-sheep
#1
Arvinda Panthee, Ayana Matsuno, Mohammad Al-Mamun, Hiroaki Sano
BACKGROUND: Garlic and its constituents are reported to have been effective in reducing methane emission and also influence glucose metabolism in body; however, studies in ruminants using garlic leaves are scarce. Garlic leaves contain similar compounds as garlic bulbs, but are discarded in field after garlic bulb harvest. We speculate that feeding garlic leaves might show similar effect as garlic constituents in sheep and could be potential animal feed supplement. Thus, we examined the effect of freeze dried garlic leaves (FDGL) on rumen fermentation, methane emission, plasma glucose kinetics and nitrogen utilization in sheep...
2017: Journal of Animal Science and Technology
https://www.readbyqxmd.com/read/28648972/diallyl-trisulfide-a-garlic-polysulfide-protects-against-as-induced-renal-oxidative-nephrotoxicity-apoptosis-and-inflammation-in-rats-by-activating-the-nrf2-are-signaling-pathway
#2
S Miltonprabu, N C Sumedha, P Senthilraja
BACKGROUND: Arsenic (As) contamination is an extremely dangerous global environmental problem as it can enter into the food chain and become bio-accumulated, endangering human health. Chronic As intoxication leads to undesirable toxic effects in various organ systems of the body, especially the kidney. Diallyl trisulfide (DATS) is an organosulfur compound which has been widely known for its uses as antibacterial, antitumorogenic, antioxidant agent and has been also reported to have anti-apoptotic and anti-inflammatory properties...
June 22, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28648292/fusarium-proliferatum-causal-agent-of-garlic-bulb-rot-in-spain-genetic-variability-and-mycotoxin-production
#3
Laura Gálvez, Monika Urbaniak, Agnieszka Waśkiewicz, Łukasz Stępień, Daniel Palmero
Fusarium proliferatum is a world-wide occurring fungal pathogen affecting several crops included garlic bulbs. In Spain, this is the most frequent pathogenic fungus associated with garlic rot during storage. Moreover, F. proliferatum is an important mycotoxigenic species, producing a broad range of toxins, which may pose a risk for food safety. The aim of this study is to assess the intraspecific variability of the garlic pathogen in Spain implied by analyses of translation elongation factor (tef-1α) and FUM1 gene sequences as well as the differences in growth rates...
October 2017: Food Microbiology
https://www.readbyqxmd.com/read/28646259/chronic-administration-of-s-allylcysteine-activates-nrf2-factor-and-enhances-the-activity-of-antioxidant-enzymes-in-the-striatum-frontal-cortex-and-hippocampus
#4
Úrzula Franco-Enzástiga, Ricardo A Santana-Martínez, Carlos A Silva-Islas, Diana Barrera-Oviedo, María Elena Chánez-Cárdenas, Perla D Maldonado
Oxidative stress plays an important role in neurodegenerative diseases and aging. The cellular defense mechanisms to deal with oxidative damage involve the activation of transcription factor related to NF-E2 (Nrf2), which enhances the transcription of antioxidant and phase II enzyme genes. S-allylcysteine (SAC) is an antioxidant with neuroprotective properties, and the main organosulfur compound in aged garlic extract. The ability of SAC to activate the Nrf2 factor has been previously reported in hepatic cells; however this effect has not been studied in normal brain...
June 24, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28646254/cytoprotective-effects-of-diallyl-trisulfide-against-valproate-induced-hepatotoxicity-new-anticonvulsant-strategy
#5
Ahmed A Shaaban, Dina S El-Agamy
Sodium valproate (VP) is an important antiepileptic drug, although it can produce deleterious hepatotoxic reactions. Diallyl trisulfide (DATS) is the principle component of garlic oil that possesses antioxidant properties. This study explored the potential hepatoprotective activity of DATS against VP-induced hepatic damage and its underlying mechanisms. In addition, the study assessed the effect of DATS on VP antiepileptic activity. Rats were given DATS once daily at two different doses along with VP for 2 weeks...
June 23, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28644404/garlic-organosulfur-compounds-reduce-inflammation-and-oxidative-stress-during-dengue-virus-infection
#6
Alex Hall, Andrea Troupin, Berlin Londono-Renteria, Tonya M Colpitts
Dengue virus (DENV) is a mosquito-borne flavivirus that causes significant global human disease and mortality. One approach to develop treatments for DENV infection and the prevention of severe disease is through investigation of natural medicines. Inflammation plays both beneficial and harmful roles during DENV infection. Studies have proposed that the oxidative stress response may be one mechanism responsible for triggering inflammation during DENV infection. Thus, blocking the oxidative stress response could reduce inflammation and the development of severe disease...
June 23, 2017: Viruses
https://www.readbyqxmd.com/read/28642133/s-allylmercaptocysteine-suppresses-the-growth-of-human-gastric-cancer-xenografts-through-induction-of-apoptosis-and-regulation-of-mapk-and-pi3k-akt-signaling-pathways
#7
Xiaosong Zhu, Xiaoyan Jiang, Ang Li, Yueyue Sun, Yan Liu, Xiao Sun, Xiuli Feng, Siying Li, Zhongxi Zhao
Gastric cancer remains as a common lethal malignancy worldwide. Developing novel anti-gastric cancer drugs with minimal side effects is necessary to address this public health issue. S-allylmercaptocysteine (SAMC), one of the water-soluble organosulfur garlic derivatives, has been demonstrated as a suppressive agent against tumors. In this study, we examined the effect of SAMC on human gastric carcinoma growth in vivo and explored the underlying mechanism. Human gastric cancer SGC-7901 cells were inoculated subcutaneously in BALB/c nude mice...
June 19, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28640234/garlic-organosulfur-compounds-reduce-inflammation-and-oxidative-stress-during-dengue-virus-infection
#8
Alex Hall, Andrea Troupin, Berlin Londono-Renteria, Tonya M Colpitts
Dengue virus (DENV) is a mosquito-borne flavivirus that causes significant global human disease and mortality. One approach to develop treatments for DENV infection and the prevention of severe disease is through investigation of natural medicines. Inflammation plays both beneficial and harmful roles during DENV infection. Studies have proposed that the oxidative stress response may be one mechanism responsible for triggering inflammation during DENV infection. Thus, blocking the oxidative stress response could reduce inflammation and the development of severe disease...
June 22, 2017: Viruses
https://www.readbyqxmd.com/read/28632417/detection-and-antigenic-profiling-of-undeclared-peanut-in-imported-garlic-using-an-xmap-multiplex-immunoassay-for-food-allergens
#9
Ronnie O Pedersen, Tim Peters, Rakhi Panda, Paul Wehling, Eric A E Garber
A shipment of imported garlic powder was suspected of containing peanut. Samples (subs) collected from the shipment displayed considerable variability in peanut antigenicity when analyzed by enzyme-linked immunosorbent assay (ELISA). This raised questions regarding whether peanut was actually present, the amount present, and the basis for the variability in antigenic content. Analyses that used an xMAP multiplex assay for the detection of peanut and additional food allergens generated responses that were characteristic of peanut...
June 20, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28629219/thermally-induced-generation-of-desirable-aroma-active-compounds-from-the-glucosinolate-sinigrin
#10
Eva Ortner, Michael Granvogl
Glucosinolates are the most abundant secondary sulfur-containing plant metabolites in the plant family of Brassicaceae. These phytochemicals are well-known for their enzymatic degradation induced by the enzyme myrosinase resulting in pungent odor impressions derived from their respective degradation products. However, up to now, only little attention has been paid to non-enzymatic thermal degradation and the release of additional aroma-active compounds. Thermal treatment is particularly important in the processing of Brassica vegetables, and, thereby, glucosinolates as precursors can act as a natural source of odorants...
June 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28624425/antiobesity-antioxidant-and-hepatoprotective-effects-of-diallyl-trisulphide-dats-alone-or-in-combination-with-orlistat-on-hfd-induced-obese-rats
#11
Sivakumar Annamalai, Lavanya Mohanam, Veena Raja, Alwin Dev, Venkataraman Prabhu
The increasing rate of obesity in the past years has become a worldwide concern and it causes many diseases. Even though, Orlistat, a synthetic anti-obesity drug approved by FDA, it causes severe side effects. DATS, a natural product from garlic have gained attention in many biological activities. The aim of the study is to determine the impact of Dially trisulpide (DATS) and its combination with Orlistat therapy on obese animals. 30 male Wistar rats (150-180g) were assigned into 5 groups (n=6). Group 1 rats received normal diet and Group 2 fed with high fat diet (HFD) for 14 weeks...
June 15, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28623504/biosorption-of-chromium-vi-from-aqueous-solutions-and-ann-modelling
#12
Soma Nag, Abhijit Mondal, Nirjhar Bar, Sudip Kumar Das
The use of sustainable, green and biodegradable natural wastes for Cr(VI) detoxification from the contaminated wastewater is considered as a challenging issue. The present research is aimed to assess the effectiveness of seven different natural biomaterials, such as jackfruit leaf, mango leaf, onion peel, garlic peel, bamboo leaf, acid treated rubber leaf and coconut shell powder, for Cr(VI) eradication from aqueous solution by biosorption process. Characterizations were conducted using SEM, BET and FTIR spectroscopy...
June 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28613443/green-pea-and-garlic-puree-model-food-development-for-thermal-pasteurization-process-quality-evaluation
#13
Ellen R Bornhorst, Juming Tang, Shyam S Sablani, Gustavo V Barbosa-Cánovas, Fang Liu
Development and selection of model foods is a critical part of microwave thermal process development, simulation validation, and optimization. Previously developed model foods for pasteurization process evaluation utilized Maillard reaction products as the time-temperature integrators, which resulted in similar temperature sensitivity among the models. The aim of this research was to develop additional model foods based on different time-temperature integrators, determine their dielectric properties and color change kinetics, and validate the optimal model food in hot water and microwave-assisted pasteurization processes...
June 14, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28613376/genetic-variability-of-garlic-accessions-as-revealed-by-agro-morphological-traits-evaluated-under-different-environments
#14
E S S Hoogerheide, J A Azevedo Filho, R Vencovsky, M I Zucchi, B W Zago, J B Pinheiro
The cultivated garlic (Allium sativum L.) displays a wide phenotypic diversity, which is derived from natural mutations and phenotypic plasticity, due to dependence on soil type, moisture, latitude, altitude and cultural practices, leading to a large number of cultivars. This study aimed to evaluate the genetic variability shown by 63 garlic accessions belonging to Instituto Agronômico de Campinas and the Escola Superior de Agricultura "Luiz de Queiroz" germplasm collections. We evaluated ten quantitative characters in experimental trials conducted under two localities of the State of São Paulo: Monte Alegre do Sul and Piracicaba, during the agricultural year of 2007, in a randomized blocks design with five replications...
May 31, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28612465/mass-spectrometry-imaging-of-low-molecular-weight-compounds-in-garlic-allium-sativum-l-with-gold-nanoparticle-enhanced-target
#15
Maria Misiorek, Justyna Sekuła, Tomasz Ruman
INTRODUCTION: Garlic (Allium sativum) is the subject of many studies due to its numerous beneficial properties. Although compounds of garlic have been studied by various analytical methods, their tissue distributions are still unclear. Mass spectrometry imaging (MSI) appears to be a very powerful tool for the identification of the localisation of compounds within a garlic clove. OBJECTIVE: Visualisation of the spatial distribution of garlic low-molecular weight compounds with nanoparticle-based MSI...
June 13, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28609097/computational-study-of-h2s-release-in-reactions-of-diallyl-polysulfides-with-thiols
#16
You-Ru Cai, Ching-Han Hu
Hydrogen sulfide (H2S) is a gasotransmitter molecule recognized for its role in cell signaling. Garlic-derived polysulfides including diallyl disulfide (DADS) and diallyl trisulfide (DATS) have been shown to release H2S. We investigated the mechanism of the reaction of DADS and DATS with biological thiols, including cysteine (Cys) and glutathione (GSH) using density functional theory. We propose that Cys and GSH react with DADS and DATS in their anionic forms. Thiol anions are much more likely to attack the sulfur atoms of DADS and DATS than the α-carbon of allyl groups...
June 13, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28607636/impact-of-garlic-tablets-on-nosocomial-infections-in-hospitalized-patients-in-intensive-care-units
#17
Hossein Madineh, Farrokh Yadollahi, Farshad Yadollahi, Ebrahim Pouria Mofrad, Majid Kabiri
BACKGROUND: Nosocomial infections are one of the main causes of mortality and morbidity in hospitals, especially in intensive care units (ICUs). OBJECTIVE: The aim of this study was to examine the impact of garlic tablets on nosocomial infections in hospitalized patients in intensive care units. METHODS: This clinical trial was carried out on 94 patients, admitted to the intensive care units in Kashani and Al-Zahra hospitals from January 21, 2014 to December 20, 2014...
April 2017: Electronic Physician
https://www.readbyqxmd.com/read/28607407/resistance-of-garlic-cultivars-to-bradysia-odoriphaga-and-its-correlation-with-garlic-thiosulfinates
#18
Guodong Zhu, Yin Luo, Ming Xue, Fangyuan Zhou, Haipeng Zhao, Guixia Ji, Fang Liu
Garlic, a widely cultivated global vegetable crop, is threatened by the underground pest Bradysia odoriphaga in China. Previous reports indicated that garlic essential oil, of which the dominant components are sulfides or thiosulfinates, exhibits insecticidal activity against pests. However, it is unclear whether the resistance of garlic to B. odoriphaga is related to thiosulfinates. Here, we compared the resistance of 10 garlic cultivars at various growth stages to B. odoriphaga by field investigation and indoor life-table data collection...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28604598/influence-of-food-characteristics-and-food-additives-on-the-antimicrobial-effect-of-garlic-and-oregano-essential-oils
#19
Juan García-Díez, Joana Alheiro, Ana Luisa Pinto, Luciana Soares, Virgilio Falco, Maria João Fraqueza, Luis Patarata
Utilization of essential oils (EOs) as antimicrobial agents against foodborne disease has gained importance, for their use as natural preservatives. Since potential interactions between EOs and food characteristics may affect their antimicrobial properties, the present work studies the influence of fat, protein, pH, aw and food additives on the antimicrobial effect of oregano and garlic EOs against Salmonella spp. and Listeria monocytogenes. Results showed that protein, pH, aw, presence of beef extract, sodium lactate and nitrates did not influence their antimicrobial effect...
June 10, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28603710/use-of-non-prescription-remedies-by-ghanaian-human-immunodeficiency-virus-positive-persons-on-antiretroviral-therapy
#20
Amos K Laar, Awewura Kwara, Priscillia A Nortey, Augustine K Ankomah, Michael P K Okyerefo, Margaret Y Lartey
BACKGROUND: Inappropriate use of non-prescription remedies by persons living with human immunodeficiency virus (PLHIV) may result in adverse events or potentiate non-adherence to prescribed medications. This study investigated the use of non-prescription remedies among PLHIV receiving antiretroviral therapy (ART) from four treatment centers in southern Ghana. METHODS: A mixed method design using quantitative and qualitative methods was used. This article focuses on the quantitative survey of 540 respondents...
2017: Frontiers in Public Health
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