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Y Shimamura, C M Walsh, S Cohen, M Aronson, U Tabori, P P Kortan, C A Durno
Background and study aims : Constitutional mismatch repair deficiency (CMMRD) syndrome, also known as biallelic mismatch repair deficiency (BMMRD) syndrome is a rare autosomal-recessive genetic disorder that has a high mortality due to malignancy in childhood and early adulthood. The small bowel phenotype in CMMRD is not well described and surveillance protocols for small bowel cancer have not been well established. This study was conducted to evaluate the usefulness and clinical impact of video capsule endoscopy (VCE) for small bowel surveillance...
August 2018: Endoscopy International Open
Carsten Gutt, Christian Jenssen, Ana-Paula Barreiros, Thorsten O Götze, Caroline S Stokes, Petra Lynen Jansen, Michael Neubrand, Frank Lammert
This guideline provides evidence-based key recommendations for the prevention, diagnosis and therapy of gallstones and upgrades the 2007 version. The guideline was developed by an interdisciplinary team of gastroenterologists and surgeons, and patient support groups under the auspice of the German Society for Gastroenterology and Metabolic Diseases and the German Society for General Surgery and Surgery of the Alimentary Tract. The guideline used structural S3 consensus-based methodology and includes statements on clinical practice, medical education, prevention, quality assurance, outcome analysis, and integration of outpatient and inpatient care for patients with gallstone diseases...
August 2018: Zeitschrift Für Gastroenterologie
Markus M Lerch
No abstract text is available yet for this article.
August 2018: Zeitschrift Für Gastroenterologie
Berna Bulut Çakmak, Güler Özkula, Sedat Işıklı, İbrahim Özkan Göncüoğlu, Serkan Öcal, Ali Ercan Altınöz, Nilgün Taşkıntuna
Previous studies have identified a link between anger and somatization. However, little is known about the associations between anger and the development and progression of Functional Gastrointestinal Disorders (FGID). The study aim was to determine the associations between FGID and anger, anxiety, and depression. Participants in this cross-sectional observational study were 109 consecutive patients aged 18-64 years with FGID at Gastroenterology Clinic of Başkent University Hospital. A control group comprised of 96 individuals with no chronic gastrointestinal disorders recruited via snowball sampling...
July 30, 2018: Psychiatry Research
The Lancet Gastroenterology Hepatology
No abstract text is available yet for this article.
September 2018: Lancet. Gastroenterology & Hepatology
Timothy D Becker, Henry C Lin, Victoria A Miller
Background: Child participation in pediatric medical visits is low. In this pilot study, we sought to better understand relationships between observed communication and child-reported perceptions of communication in a clinical setting. Materials and methods: For this cross-sectional observational study, pediatric gastroenterology appointments (n=39) were videotaped and coded to quantify various adult affective (eg, chit-chat, empathy) and facilitative (eg, asking questions, encouraging responses) behaviors toward the child, interference with child participation (eg, interrupting or ignoring child), and child verbal participation...
2018: Patient Preference and Adherence
Sharron Rushton, Margaret J Carman
Noncardiac chest pain is an angina-type discomfort without indication of ischemia. Diagnosis can be difficult because of its heterogeneous nature. Classification varies by specialty; gastroenterology uses the terminology gastroesophageal reflux disease related versus non-gastroesophageal reflux disease related. Other disciplines recognize noncardiac chest pain etiologies as having gastrointestinal, musculoskeletal, psychiatric, or pulmonary/other as underlying etiologies. Diagnostics yield a specific cause for effective treatment, which is aimed at the underlying etiology, but it is not always possible...
September 2018: Nursing Clinics of North America
(no author information available yet)
No abstract text is available yet for this article.
September 2018: Journal of Clinical Gastroenterology
Sarah Ballou, Eaman Alhassan, Elise Hon, Cara Lembo, Vikram Rangan, Prashant Singh, William Hirsch, Thomas Sommers, Johanna Iturrino, Judy Nee, Anthony Lembo
BACKGROUND: Poor sleep quality is common among patients with gastrointestinal (GI) disorders. However, few studies have assessed the presence of insomnia or reported circadian preferences and none have directly compared sleep between common GI conditions. AIMS: To compare clinical sleep characteristics in patients presenting to a tertiary care GI clinic for irritable bowel syndrome (IBS), functional dyspepsia (FD), inflammatory bowel disease (IBD), gastroesophageal reflux disease (GERD), and celiac disease (CD)...
August 9, 2018: Digestive Diseases and Sciences
Antonio Facciorusso, Rosario Vincenzo Buccino, Nicola Muscatiello
Quality is a key focus for gastrointestinal endoscopy and main international gastroenterology societies instituted specific task forces focused on this issue. Endoscopic ultrasound (EUS) represents one of the most fascinating fields to explore in gastrointestinal endoscopy due to its relatively limited availability out of high-volume centers. This leads to a particular need to define widely accepted quality indicators (QIs) and the ways to measure them. The current manuscript reviews these indicators in light of their impact on common clinical practice...
July 2018: Annals of Translational Medicine
Alexander Krumov Katzarov, Zdravko Ivanov Dunkov, Ivan Popadiin, Krum Sotirov Katzarov
Endoscopic retrograde cholangiopancreatography (ERCP) is invasive therapeutic procedure demanding specific individual approach for learning and mastering. It is associated with greater morbidity and mortality than any other procedure in gastroenterology. The risk for complications and harm for patient inevitably require strict guidelines to be followed regarding training, certification and proficiency. In an attempt to reduce the risk of complications, various endoscopic societies worldwide have established so called "Quality measures" which proved to be the back bone for safety and quality in ERCP...
July 2018: Annals of Translational Medicine
Mihaela Filip, Valentina Tzaneva, Dan L Dumitrascu
Background and aim: Fecal transplantation or fecal material transplantation (FMT) became a hot topic in gastroenterology in recent years. Therefore it is important to disseminate the up-to-date information on FMT. The aim of the paper is to review the knowledge on FMT and its clinical applications. Methods: An extensive review of the literature was carried out. Titles from Pubmed were searched and analyzed. A narrative review has been written with emphasis on indications of FMT in different conditions...
July 2018: Clujul Medical (1957)
Vincenzo Savarino, Cesare Tosetti, Edoardo Benedetto, Debora Compare, Gerardo Nardone
The introduction of proton pump inhibitors (PPIs) into clinical practice about thirty years ago has greatly improved our therapeutic approach to acid-related diseases for their well-recognized efficacy and safety. Despite the well-defined indications, however, the use of PPIs continues to grow every year in both western and eastern countries and this phenomenon poses serious queries that include the onset of potential adverse effects and the increase in health care costs. The major reason explaining this worrying market expansion is the inappropriate use of PPIs...
July 17, 2018: Digestive and Liver Disease
Nicholas J Talley
American Journal of Gastroenterology is pleased to publish notices of educational events relating to topics covered in the Journal. Announcements in this column are limited to the dates, title, location, and main sponsor of the course; and the name, address, and telephone and fax numbers for further information.
August 2018: American Journal of Gastroenterology
Sucharita Anand, Anmol Singh Rai, Rohit Chhirolya, Vimal Kumar Paliwal
Patients suffering from acute intractable vomiting are usually treated in the Gastroenterology department. The causes of acute intractable vomiting range from acute pancreatitis and acute intestinal obstruction to cardiac causes like acute myocardial infarction and neurological causes like posterior circulation stroke. However, most of the underlying causes of acute intractable vomiting also produce other telltale signs/symptoms. Rarely, isolated acute intractable vomiting may be the initial symptom of a recurrent neurological syndrome of neuromyelitis optica spectrum disorder (NMOSD)...
August 8, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Christopher B Eke, Robin A Brown, Ronalda J De Lacy, Komala Pillay, Elizabeth A Goddard
Collagenous gastritis is an uncommon gastrointestinal disease in children. Its cause remains uncertain. It may present as severe hypoproteinaemia manifesting as generalized oedema.We report a 15 months old female who presented with pica, generalized body oedema and diarrhoea. Diagnostic workup revealed gastric replacement of the lamina propria by hyalinized collagen on histology.This case seeks to highlight the need for early paediatric gastroenterology referral including oesophagogastroduodenoscopy with multiple tissue biopsies as part of a broad diagnostic workup in children with non-specific gastrointestinal symptoms to improve diagnostic yield and enable accurate histologic diagnosis, so that appropriate therapy can be timeously applied...
August 3, 2018: Journal of Tropical Pediatrics
Birgit Vogt, Tobias Mai, Johanna Feuchtinger, Helene Maucher, Barbara Strohbücker, Christa Flechinger, Birgit Alpers, Martina Roes
BACKGROUND: Demographic changes result in a higher prevalence of patients suffering from dementia in hospital. In Germany, epidemiological data of this target group are scarce and prevalence rates from university hospitals (UH) are not available. The prevalence rates and distribution were analyzed on the basis of ICD-10-GM (German modification) routine data METHOD: A secondary analysis on ICD-10-GM main and secondary diagnoses of dementia from 2014 and 2015 from 5 UH was performed. All patients admitted to hospital for at least 24 h and ≥18 years old (2014 n = 187,168; 2015 n = 189,040) were included...
August 3, 2018: Zeitschrift Für Gerontologie und Geriatrie
Anne Thushara Matthias, Anthony Nilesh Ranjeev Fernandopulle, Suranjith L Seneviratne
OBJECTIVES: There has been a global increase in the incidence and prevalence of NAFLD. We assessed the knowledge and awareness of NAFLD among gastroenterology doctors in three state sector hospitals. RESULTS: 80 medical officers and 58 post-graduate trainee doctors/consultants responded. 110 (79.7%) considered NAFLD a major health problem whilst 97 (70.3%) thought the prevalence of NAFLD was 10-40%. 52.9% saw 12-24 patients with NAFLD/year. A vast majority knew the risk factors for NAFLD: 127 (92...
August 3, 2018: BMC Research Notes
Cheng Zhang, Xuanwei Li, Liu Liu, Lijuan Gao, Shiyi Ou, Jianming Luo, Xichun Peng
The specialty of gastroenterology will be affected profoundly by the ability to modify the gastrointestinal microbiota through the use of antibiotics. This study investigated the in vivo effect of roxithromycin on gut bacteria and gene expression of colonic epithelial cells (CECs) using microbial 16S rDNA and colonic epithelial cell RNA sequencing, respectively. The results showed that roxithromycin distinctly lowered the microbial diversity in both the small intestine and cecum and altered the compositions of bacteria at both the phylum and genus levels, including the reduction of some bacteria beneficial to the hosts' health...
August 2, 2018: Applied Microbiology and Biotechnology
Carlos H Lifschitz, Mohamad Miqdady, Flavia Indrio, Joseph Haddad, Eslam Tawfik, Akbari AbdelHak, Nezha Mouane, Mohamad Salah, Katayoun Khatami, Beheshteh Olang, Yvan Vandenplas
BACKGROUND: Iron deficiency (ID) with or without anemia is associated with impaired mental and psychomotor development. Given the paucity of information on physicians' knowledge and practices on iron (Fe) supplementation and impact of ID in the Middle East and North Africa (MENA), it was felt important to conduct a survey. METHOD: A group of expert physicians developed a questionnaire that was randomly distributed among MENA doctors to assess their knowledge and practices on introduction of complementary feeding, impact of ID, its prevention and their impression on prevalence of ID...
August 2, 2018: Journal of Pediatric Gastroenterology and Nutrition
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