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https://www.readbyqxmd.com/read/29325638/implantable-cardioverter-defibrillators-in%C3%A2-children-and-adolescents-with-brugada%C3%A2-syndrome
#1
M Cecilia Gonzalez Corcia, Juan Sieira, Gudrun Pappaert, Carlo de Asmundis, Gian Battista Chierchia, Mark La Meir, Andrea Sarkozy, Pedro Brugada
BACKGROUND: Young patients presenting with symptomatic Brugada syndrome have very high risks for ventricular arrhythmias and should be carefully considered for implantable cardioverter-defibrillator (ICD) placement. However, this therapy is associated with high rates of inappropriate shocks and device-related complications. OBJECTIVES: This study investigated clinical features, management, and long-term follow-up of young patients with Brugada syndrome and ICD. METHODS: Patients diagnosed with Brugada syndrome, who underwent implantation of an ICD at an age of ≤20 years, were studied...
January 16, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29321120/evaluating-vancomycin-and-piperacillin-tazobactam-in-emergency-department-patients-with-severe-sepsis-and-septic-shock
#2
Christina Le, Frank Chu, Ronald Dunlay, Julian Villar, Peter Fedullo, Gabriel Wardi
STUDY OBJECTIVE: To determine the frequency and cause of inadequate initial antibiotic therapy with vancomycin and piperacillin-tazobactam in patients with severe sepsis and septic shock in the emergency department (ED), characterize its impact on patient outcomes, and identify patients who would benefit from an alternative initial empiric regimen. METHODS: Retrospective cohort study conducted between 2012 and 2015 in which 342 patients with culture-positive severe sepsis or septic shock who received initial vancomycin and piperacillin-tazobactam were reviewed to determine appropriateness of antimicrobial therapy, risk factors for inappropriate use, and outcome data...
December 29, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29317975/subcutaneous-implantable-cardioverter-defibrillators-implantation-without-defibrillation-threshold-testing-a-single-center-experience
#3
Bandar Al-Ghamdi, Azam Shafquat, Nadiah Alruwaili, Shisamma Emmanual, Mohamed Shoukri, Yaseen Mallawi
Background: Subcutaneous implantable cardioverter defibrillator (S-ICD) system has been proven to be an effective therapy for prevention of sudden cardiac death (SCD) in selected patients. Although the Shockless IMPLant Evaluation (SIMPLE) trial has shown that defibrillation threshold (DFT) testing is not necessary for transvenous ICD (TV-ICD) systems, it is still recommended for S-ICD systems. We aimed to study the efficacy and safety of S-ICD implantation without DFT in our Heart Center with the comparison of S-ICD patients' outcome to those with a single chamber TV-ICD without DFT in the same period...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29310974/sepsis-in-tropical-regions-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#4
Steven McGloughlin, Guy A Richards, Mohd Basri Mat Nor, Shirish Prayag, Tim Baker, Pravin Amin
Sepsis and septic shock in the tropics are caused by a wide array of organisms. These infections are encountered mainly in low and middle-income countries (LMIC) where a lack of infrastructure and medical facilities contribute to the high morbidity and mortality. Published sepsis guidelines are based on studies primarily performed in high income countries and as such recommendations may or may not be relevant to practice in the tropics. Failure to adhere to guidelines, particularly among non-intensive care specialists even in high-income countries, is an area of concern for sepsis management...
December 30, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29285623/right-versus-left-parasternal-electrode-position-in-the-entirely-subcutaneous-icd
#5
Markus Bettin, Dirk Dechering, Gerrit Frommeyer, Robert Larbig, Andreas Löher, Florian Reinke, Julia Köbe, Lars Eckardt
OBJECTIVES: The subcutaneous implantable cardioverter defibrillator (S-ICD®) has been established as an alternative to conventional transvenous ICD for the prevention of sudden cardiac death. Initial studies have shown safety and efficacy of the system with a left parasternal (LP) electrode. However, several case studies reported a right parasternal (RP) position. The purpose of this study was to analyze shock efficacy and safety of an RP electrode position. METHODS: Between June 2010 and May 2016, 120 S-ICD® were implanted at our institution...
December 28, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29277687/defibrillator-shocks-and-their-impact-on-objective-and-subjective-patient-outcomes-results-from-the-painfree-sst-clinical-trial
#6
Samuel F Sears, Lindsey Rosman, Shingo Sasaki, Yusuke Kondo, Laurence D Sterns, Edward J Schloss, Takashi Kurita, Albert Meijer, Judith Raijmakers, Bart Gerritse, Angelo Auricchio
BACKGROUND: The impact of ICD shock on device-measured activity and patient reported outcomes is unknown. OBJECTIVE: The purpose of this study was to analyze the acute and long-term effects of ICD shock on objective behavioral data (i.e., device-based physical activity) and subjective patient reported outcomes (e.g., quality of life and shock anxiety). METHODS: The PainFree SST clinical trial included 2,770 patients with a single or dual-chamber ICD, or cardiac resynchronization defibrillator (CRT-D) who were followed for 22 ± 9 months...
December 22, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29251799/atrioventricular-junction-ablation-in-patients-with-atrial-fibrillation-treated-with-cardiac-resynchronization-therapy-positive-impact-on-ventricular-arrhythmias-implantable-cardioverter-defibrillator-therapies-and-hospitalizations
#7
Maurizio Gasparini, Axel Kloppe, Maurizio Lunati, Frédéric Anselme, Maurizio Landolina, Jose Bautista Martinez-Ferrer, Alessandro Proclemer, Giovanni Morani, Mauro Biffi, Renato Ricci, Roberto Rordorf, Lorenza Mangoni, Laura Manotta, Andrea Grammatico, Francisco Leyva, Giuseppe Boriani
AIMS: We sought to determine whether atrioventricular junction ablation (AVJA) in patients with cardiac resynchronization therapy (CRT) implantable cardioverter-defibrillator (ICD) and with permanent atrial fibrillation (AF) has a positive impact on ICD shocks and hospitalizations compared with rate-slowing drugs. METHODS AND RESULTS: This is a pooled analysis of data from 179 international centres participating in two randomized trials and one prospective observational research...
December 18, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29246830/relative-timing-of-near-field-and-far-field-electrograms-can-determine-tachyarrhythmia-site-of-origin
#8
Jane Caldwell, Lorne Gula, Fariha Sadiq Ali, Rodrigo I Miranda, Hoshiar Abdollah, Adrian Baranchuk, Kevin Michael, Christopher Simpson, Damian P Redfearn
BACKGROUND: Despite improving algorithms, inappropriate shocks for supraventricular arrhythmias (SVT) still occur in a significant number of patients with implantable cardioverter defibrillators (ICD). This makes the discovery of novel discriminators that use existing ICD hardware, an attractive proposition. OBJECTIVE: We hypothesised that the delay of activation onset from the device detected, far field electrogram(EGM) to the near field, bipole EGM would allow differentiation of ventricular tachycardias (VT) from SVTs...
December 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29246807/inappropriate-shock-due-to-air-entrapment-in-the-pocket-of-a-subcutaneous-implantable-cardioverter-defibrillator
#9
Markus Linhart, José María Tolosana, Fredy Chipa, Emilce Trucco, Lluís Mont
No abstract text is available yet for this article.
December 12, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29225838/multiple-inappropriate-implantable-cardiac-defibrillator-therapies-in-rapid-succession
#10
Jeffrey A Marbach, Colin Yeo, Martin S Green, Girish M Nair
Inappropriate implantable cardiac defibrillator (ICD) shocks are associated with significant morbidity and have the potential to trigger ventricular arrhythmias, cardiac decompensation, and death. We present a case of multiple inappropriate ICD therapies in rapid succession due electromagnetic interference from a Dr-Ho's transcutaneous electric nerve stimulator machine, and subsequently from a faulty electrical outlet.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29222869/new-generation-cardioverter-defibrillator-lead-with-a-floating-atrial-sensing-dipole-long-term-performance
#11
Erdal Safak, Giuseppe D Ancona, Hilmi Kaplan, Evren Caglayan, Stephan Kische, Alper Öner, Hüseyin Ince, Jasmin Ortak
OBJECTIVES: Study aim is to present the long-term performance of a new generation implantable cardioverter defibrillator (ICD) electrode with floating atrial dipole (Linox S DX, Biotronik). BACKGROUND: The single ICD electrode with a floating dipole in the atrial chamber was introduced about 15 years ago to overcome risk of inappropriate shock. METHODS: After implant, internal ECG data were prospectively collected via tele-monitoring (Home Monitoring, Biotronik)...
December 9, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29221700/acute-and-long-term-results-after-contemporary-subcutaneous-implantable-cardioverter-defibrillator-implantation-a-single-center-experience
#12
Miguel A Arias, Marta Pachón, Finn Akerström, Alberto Puchol, Cristina Martín-Sierra, Luis Rodríguez-Padial
INTRODUCTION AND OBJECTIVES: The subcutaneous implantable cardioverter-defibrillator (S-ICD) has emerged as an alternative to the transvenous defibrillator. The incidence of complications is similar, with inappropriate shocks (IS) being more frequent than those occurring with contemporary programming of transvenous defibrillators. Several improvements have been implemented after the S-ICD was approved for use in Europe in 2009. This study reports the results of S-ICD use in a single center, whose experience began late, at the end of 2013...
December 5, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29180909/wearable-cardioverter-defibrillators-for-the-prevention-of-sudden-cardiac-arrest-a-health-technology-assessment-and-patient-focus-group-study
#13
Sabine Ettinger, Michal Stanak, Piotr Szymański, Claudia Wild, Romana Tandara Haček, Darija Erčević, Renata Grenković, Mirjana Huić
Aim: To summarize the evidence on clinical effectiveness and safety of wearable cardioverter defibrillator (WCD) therapy for primary and secondary prevention of sudden cardiac arrest in patients at risk. Methods: We performed a systematic literature search in databases including MEDLINE via OVID, Embase, the Cochrane Library, and CRD (DARE, NHS-EED, HTA). The evidence obtained was summarized according to GRADE methodology. A health technology assessment (HTA) was conducted using the HTA Core Model® for rapid relative effectiveness assessment...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29177981/long-term-incidence-of-inappropriate-shocks-in-patients-with-implantable-cardioverter-defibrillators-in-clinical-practice-an-underestimated-complication
#14
Daniel Hofer, Jan Steffel, David Hürlimann, Laurent Haegeli, Thomas F Lüscher, Firat Duru, Urs Eriksson, Nazmi Krasniqi
BACKGROUND: Implantable cardioverter defibrillators (ICD) are life-saving device therapy, and patients often carry devices for decades with interim pulse generator exchanges. Inappropriate shocks are associated with impaired quality of life and increased mortality, but available data on their incidence and etiology outside of clinical trials is limited and usually restricted to the lifespan of a singular device. We hypothesized that the incidence in clinical practice is underestimated and aimed this study to retrospectively assess the long-term incidence and etiology of inappropriate shocks in a real-world cohort of patients with multiple ICDs over a long follow-up period...
November 25, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29157723/implantable-cardioverter-defibrillator-therapy-in-hypertrophic-cardiomyopathy-a-simple-substudy
#15
Mate Vamos, Jeff S Healey, Jia Wang, Stuart J Connolly, Philippe Mabo, Lieselot VanErven, Josef Kautzner, Michael Glikson, Jorg Neuzner, Gilles O'Hara, Xavier Vinolas, Frederik Gadler, Stefan H Hohnloser
BACKGROUND: Patients with hypertrophic cardiomyopathy (HCM) are considered to be at high risk for elevated defibrillation thresholds, peri-procedural complications, and failed appropriate shocks. OBJECTIVE: To determine the value of defibrillation testing in HCM patients undergoing ICD implantation. METHODS: Defibrillation thresholds, perioperative complications, and long-term outcomes were compared between patients with HCM, and those with ischemic or dilated cardiomyopathy (ICM/DCM) enrolled in the SIMPLE trial...
November 17, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29122811/comparison-of-inappropriate-shocks-and-other-health-outcomes-between-single-and-dual-chamber-implantable-cardioverter-defibrillators-for-primary-prevention-of-sudden-cardiac-death-results-from-the-cardiovascular-research-network-longitudinal-study-of-implantable
#16
Pamela N Peterson, Robert T Greenlee, Alan S Go, David J Magid, Andrea Cassidy-Bushrow, Romel Garcia-Montilla, Karen A Glenn, Jerry H Gurwitz, Stephen C Hammill, John Hayes, Alan Kadish, Kristi Reynolds, Param Sharma, David H Smith, Paul D Varosy, Humberto Vidaillet, Chan X Zeng, Sharon-Lise T Normand, Frederick A Masoudi
BACKGROUND: In US clinical practice, many patients who undergo placement of an implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death receive dual-chamber devices. The superiority of dual-chamber over single-chamber devices in reducing the risk of inappropriate ICD shocks in clinical practice has not been established. The objective of this study was to compare risk of adverse outcomes, including inappropriate shocks, between single- and dual-chamber ICDs for primary prevention...
November 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29122697/early-administration-of-appropriate-antimicrobial-agent-to-improve-the-outcome-of-carbapenem-resistant-acinetobacter-baumannii-complex-bacteremic-pneumonia
#17
Seong Yeon Park, Eun Jung Lee, Tark Kim, Shi Nae Yu, Ki-Ho Park, Mi Suk Lee, Se Yoon Park, Min Hyok Jeon, Tae Hyong Kim, Eun Ju Choo
BACKGROUND: Carbapenem resistant Acinetobacter baumannii complex (CRABC) is an emerging pathogen that causes bloodstream infections and nosocomial pneumonia. This study aimed to describe the severe infection associated with CRABC bacteremic pneumonia and to investigate risk factors for 28-day mortality. METHODS: All patients ≥18 years of age with a CRABC bacteremic pneumonia were enrolled retrospectively at five teaching hospitals in South Korea. Empirical antimicrobial therapy was defined as appropriate if administration of at least one antimicrobial agent, to which the causative pathogen was susceptible, more than 48 hours, within 5 days of the onset of bacteremia...
November 6, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29120016/the-subcutaneous-implantable-cardioverter-defibrillator-in-daily-clinical-practice
#18
Tardu Özkartal, Alexander Breitenstein, Ardan M Saguner, Devdas T Inderbitzin, Markus Wilhelm, Stefano Benussi, Francesco Maisano, Thomas F Lüscher, Frank Ruschitzka, Jan Steffel
INTRODUCTION: In Switzerland, the first implantation of a subcutaneous implantable cardioverter-defibrillator (S-ICD) took place in November 2012. Up until the end of 2016, a total of 111 S-ICDs have been implanted. The aim of this study was to summarise the experience of a tertiary centre in Switzerland and to discuss the results in the context of international registries. METHODS: All patients in whom an S-ICD was implanted between November 2012 and the end of December 2016 at the University Heart Centre Zurich were included in this study...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29111168/standardized-programming-to-reduce-the-burden-of-inappropriate-therapies-in-implantable-cardioverter-defibrillators-single-centre-follow-up-results
#19
U Boles, E Gul, L Fitzgerald, F Sadiq Ali, Christine Nolan, K Aldworth-Gaumond, D R Redfearn, A Baranchuk, B Glover, C Simpson, H Abdollah, K A Michael
BACKGROUND: Current algorithms and device morphology templates have been proposed in current Implantable Cardioverter-Defibrillators (ICDs) to minimize inappropriate therapies (ITS), but this has not been completely successful. AIM: Assess the impact of a deliberate strategy of using an atrial lead implant with standardized parameters; based on all current ICD discriminators and technologies, on the burden of ITS. METHOD: A retrospective single-centre analysis of 250 patients with either dual chamber (DR) ICDs or biventricular ICDs (CRTDs) over a (41...
October 27, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29107755/interaction-between-shock-coils-increased-the-incidence-of-inappropriate-therapies-and-lead-failure-in-implantable-cardioverter-defibrillator
#20
Mohammad El Garhy, Marc-Alexander Ohlow, Bernward Lauer
AIMS: Shock coil interaction in patients with multiple implantable cardioverter defibrillator (ICD) leads is occasionally observed. We aimed to evaluate the incidence of shock coil interaction and its clinical relevance. METHODS AND RESULTS: All ICD patients (646 patients) who came to follow up control in our ICD ambulance between January 1, 2011, and December 31, 2011 in the department of cardiology in Bad Berka hospital were retrospectively evaluated in this study...
October 28, 2017: Indian Pacing and Electrophysiology Journal
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