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Cpap in newborn

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https://www.readbyqxmd.com/read/30186507/neonatology-paediatrics-and-paediatric-virology-on-a-british-island-an-interview-with-neonatologist-dr-prakash-thiagarajan-isle-of-man
#1
Ioannis N Mammas, Demetrios A Spandidos
Dr Prakash Thiagarajan, consultant neonatologist and clinical director at Women's and Children's Division at Noble's Hospital on the Isle of Man, is one of the most talented neonatologists in the UK with a great experience in newer modes of infant ventilation and the application of technology in neonatal medicine and paediatrics. Under his leadership, the new neonatal intensive care unit (NICU) at Noble's Hospital is a state-of-the-art neonatal unit offering the very highest standards of care for critically ill babies on the island...
September 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/30131296/the-effect-of-inhaled-salbutamol-on-the-outcomes-of-transient-tachypnea-of-the-newborn
#2
Arash Malakian, Masoud Dehdashtian, Mohammad Raza Aramesh, Mohammad Hassan Aletayeb, Solmaz Heidari
BACKGROUND: Transient tachypnea of the newborn (TTN) is a self-limiting disease that results from a reduction in the rate of lung fluid clearance in neonates. A delay in lung fluid absorption in neonates disrupts the transition from intrauterine to extrauterine life. Use of beta-adrenergic antagonists, such as salbutamol, accelerates lung fluid clearance. The current study aimed to evaluate the effect of inhaled salbutamol on the clinical progression of TTN treatment. METHODS: In the current triple-blind clinical trial, a total of 148 inpatients diagnosed with TTN were randomly divided into 2 groups...
August 18, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30049727/supporting-breathing-of-preterm-infants-at-birth-a-narrative-review
#3
REVIEW
Tessa Martherus, André Oberthuer, Janneke Dekker, Stuart B Hooper, Erin V McGillick, Angela Kribs, Arjan B Te Pas
Most very preterm infants have difficulty aerating their lungs and require respiratory support at birth. Currently in clinical practice, non-invasive ventilation in the form of continuous positive airway pressure (CPAP) and positive pressure ventilation (PPV) is applied via facemask. As most very preterm infants breathe weakly and unnoticed at birth, PPV is often administered. PPV is, however, frequently ineffective due to pressure settings, mask leak and airway obstruction. Meanwhile, high positive inspiratory pressures and spontaneous breathing coinciding with inflations can generate high tidal volumes...
July 26, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29870158/lung-ultrasonography-score-versus-chest-x-ray-score-to-predict-surfactant-administration-in-newborns-with-respiratory-distress-syndrome
#4
Alessandro Perri, Riccardo Riccardi, Rossella Iannotta, Domenico V Di Molfetta, Roberta Arena, Giovanni Vento, Enrico Zecca
OBJECTIVES: We aim to verify the diagnostic accuracy of a lung ultrasonography (LUS) score to early predict the need for surfactant therapy in newborns with respiratory distress syndrome (RDS), and to compare it with a chest X-ray score. METHODS: In this prospective diagnostic accuracy study we included all newborns admitted for respiratory distress and initially treated with nasal CPAP. LUS was performed within 2 h from nasal CPAP positioning and in any case before surfactant administration...
September 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29800541/neonatal-outcomes-of-elective-early-term-births-after-demonstrated-fetal-lung-maturity
#5
Alan T N Tita, Kathleen A Jablonski, Jennifer L Bailit, William A Grobman, Ronald J Wapner, Uma M Reddy, Michael W Varner, John M Thorp, Kenneth J Leveno, Steve N Caritis, Jay D Iams, George Saade, Yoram Sorokin, Dwight J Rouse, Sean C Blackwell, Jorge E Tolosa
BACKGROUND: Studies of early-term birth after demonstrated fetal lung maturity show that respiratory and other outcomes are worse with early-term birth (370 -386 weeks) even after demonstrated fetal lung maturity when compared with full-term birth (390 -406 weeks). However, these studies included medically indicated births and are therefore potentially limited by confounding by the indication for delivery. Thus, the increase in adverse outcomes might be due to the indication for early-term birth rather than the early-term birth itself...
September 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29768512/infant-cpap-for-low-income-countries-an-experimental-comparison-of-standard-bubble-cpap-and-the-pumani-system
#6
COMPARATIVE STUDY
Markus Falk, Snorri Donaldsson, Thomas Drevhammar
INTRODUCTION: Access to inexpensive respiratory support to newborn infants improves survival in low-income countries. Standard bubble continuous positive airway pressure (CPAP) has been extensively used worldwide for more than 30 years. One project aimed at providing affordable CPAP is the Pumani system developed by Rice 360°. Compared to standard bubble CPAP the system has an unconventional design. The aim was to compare the Pumani system with two traditional bubble CPAP systems, focusing on in-vitro performance and safety...
2018: PloS One
https://www.readbyqxmd.com/read/29746270/evidence-regarding-the-use-of-bubble-continuous-positive-airway-pressure-in-the-extremely-low-birth-weight-infant-benefits-challenges-and-implications-for-nursing-practice
#7
Samantha Alessi
BACKGROUND: Gentle ventilation with optimal oxygenation is integral to prevention of chronic lung disease in the extremely low birth-weight (ELBW) infant. Various types of noninvasive ventilation are used in neonatal intensive care units worldwide. Bubble continuous positive airway pressure (BCPAP) has been in use in newborn intensive care since 1975. PURPOSE: To synthesize the current evidence on the use of BCPAP in the ELBW infant and its relationship to outcomes, particularly morbidity and mortality...
June 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29728414/t-piece-resuscitators-how-do-they-compare
#8
Murray Hinder, Alistair McEwan, Thomas Drevhammer, Snorri Donaldson, Mark Brian Tracy
BACKGROUND: The T-piece resuscitator (TPR) has seen increased use as a primary resuscitation device with newborns. Traditional TPR design uses a high resistance expiratory valve to produce positive end expiratory pressure (PEEP) or continuous positive airway pressure (CPAP) at resuscitation. A new TPR device that uses a dual flow ratio valve (fluidic flip) to produce PEEP/CPAP is now available (rPAP). We aimed to compare the measured ventilation performance of different TPR devices in a controlled bench test study...
May 4, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29701312/tidal-breath-eno-measurements-in-a-cohort-of-unsedated-hospitalized-neonates-a-method-validation
#9
Birgitte J Schmidt, Pauline S Reim, Andreas K Jensen, Per Albertsen, Gorm Greisen, Inger M Jørgensen
AIM: Exhaled Nitric oxide (eNO) is an inflammatory marker. In 2002 Hall et al. [J Appl Physiol. 92:59-66] established an infant eNO measurement method, fulfilling four criteria of feasibility: simple, non-invasive, without impact on the natural breathing pattern, and accounting for flow by NO output (V'NO). Although tidal breathing is accepted as an eNO measurement method in uncooperative patients, it is seldom used outside research labs. The variability and lack of validated methods have restrained from exploring the area in preterm and term neonates the last years...
June 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29514813/evaluation-of-try-an-algorithm-for-neonatal-continuous-positive-airways-pressure-in-low-income-settings
#10
Caroline Crehan, Tim Colbourn, Michelle Heys, Elizabeth Molyneux
BACKGROUND: Non-invasive respiratory support using bubble continuous positive airway pressure (bCPAP) is useful in treating babies with respiratory distress syndrome. Despite its proven clinical and cost-effectiveness, implementation is hampered by the inappropriate administration of bCPAP in low-resource settings. A clinical algorithm-'TRY' (based on Tone: good; Respiratory distress; Yes, heart rate above 100 beats/min)-has been developed to correctly identify which newborns would benefit most from bCPAP in a teaching hospital in Malawi...
August 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29393237/high-flow-nasal-cannula-versus-nasal-continuous-positive-airway-pressure-for-primary-respiratory-support-in-preterm-infants-with-respiratory-distress-a-randomized-controlled-trial
#11
Srinivas Murki, Jayesh Singh, Chiragkumar Khant, Swarup Kumar Dash, Tejo Pratap Oleti, Percy Joy, Nandkishor S Kabra
BACKGROUND: Nasal continuous positive airway pressure (nCPAP) is the standard noninvasive respiratory support for newborns with respiratory distress. Evidence for high-flow nasal cannula (HFNC) as an alternative mode of respiratory support is inconclusive. OBJECTIVE: The aim of this work was to evaluate whether HFNC is not inferior to nCPAP in reducing the need for higher respiratory support in the first 72 h of life when applied as a noninvasive respiratory support mode for preterm neonates with respiratory distress...
2018: Neonatology
https://www.readbyqxmd.com/read/29325421/effects-of-underwater-bubble-cpap-on-very-low-birth-weight-preterm-newborns-in-the-delivery-room-and-after-transport-to-the-neonatal-intensive-care-unit
#12
Vera Lucia Barros Abelenda, Tania Cristina Oliveira Valente, Cirlene Lima Marinho, Agnaldo José Lopes
The development of less invasive ventilatory strategies in very-low-birth-weight (VLBW) preterm newborns has been a growing concern in recent decades. This study aimed to measure differences in the clinical progression of preterm newborns using two distinct periods in a university hospital: before and after using underwater bubble continuous positive airway pressure (ubCPAP). This is a retrospective study of VLBW preterm newborns with gestational ages less than or equal to 32 weeks admitted to the neonatal intensive care unit...
June 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/28965435/early-rescue-neopuff-for-infants-with-transient-tachypnea-of-newborn-a-randomized-controlled-trial
#13
Amani Mahmoud Osman, Rania Ali El-Farrash, Enas Hussein Mohammed
OBJECTIVE: To examine the efficacy of early continuous positive airway pressure (CPAP), delivered using a T-piece-based infant resuscitator (Neopuff) via a face mask, in reducing the severity and duration of transient tachypnea of the newborn (TTN) as well as testing a hypothesis suggesting that rapid clearance of fetal lung fluid to the circulation via CPAP would increase plasma B-type natriuretic peptide (BNP). METHODS: A randomized controlled trial (NCT01859533) was conducted on 64 late preterm/term neonates, delivered by cesarean section and presented by respiratory distress shortly after birth...
October 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28856971/a-comparison-of-the-effects-of-invasive-mechanic-ventilation-surfactant-therapy-and-non-invasive-nasal-continuous-positive-airway-pressure-in-preterm-newborns
#14
Muhittin Celik, Ali Bulbul, Sinan Uslu, Mesut Dursun, Omer Guran, Evrim Kıray Bas, Selda Arslan, Umut Zubarioglu
AIMS: This study compared the early-term outcomes of mechanical ventilation (MV)/surfactant treatment with nasal-continuous positive airway pressure (nCPAP) in preterm infants with respiratory distress syndrome (RDS). MATERIALS AND METHODS: Data from newborns born between ≥24 and ≤32 weeks of gestation, hospitalized at our newborn intensive care unit, and diagnosed with RDS between January 2009 and February 2012 were analyzed. RESULTS: Of 193 newborns with RDS who were enrolled in the study, 113 were treated with nCPAP and 80 with MV at a level of 57...
December 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28645982/a-multicentre-randomised-controlled-non-inferiority-trial-comparing-nasal-high-flow-with-nasal-continuous-positive-airway-pressure-as-primary-support-for-newborn-infants-with-early-respiratory-distress-born-in-australian-non-tertiary-special-care-nurseries
#15
MULTICENTER STUDY
Brett J Manley, Calum T Roberts, Gaston R B Arnolda, Ian M R Wright, Louise S Owen, Kim M Dalziel, Jann P Foster, Peter G Davis, Adam G Buckmaster
INTRODUCTION: Nasal high-flow (nHF) therapy is a popular mode of respiratory support for newborn infants. Evidence for nHF use is predominantly from neonatal intensive care units (NICUs). There are no randomised trials of nHF use in non-tertiary special care nurseries (SCNs). We hypothesise that nHF is non-inferior to nasal continuous positive airway pressure (CPAP) as primary support for newborn infants with respiratory distress, in the population cared for in non-tertiary SCNs. METHODS AND ANALYSIS: The HUNTER trial is an unblinded Australian multicentre, randomised, non-inferiority trial...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28545875/regional-volume-characteristics-of-the-preterm-infant-receiving-first-intention-continuous-positive-airway-pressure
#16
Risha Bhatia, Peter G Davis, David G Tingay
OBJECTIVE: To determine whether applying nasal continuous positive airway pressure (CPAP) using systematic changes in continuous distending pressure (CDP) results in a quasi-static pressure-volume relationship in very preterm infants receiving first intention CPAP in the first 12-18 hours of life. STUDY DESIGN: Twenty infants at <32 weeks' gestation with mild respiratory distress syndrome (RDS) managed exclusively with nasal CPAP had CDP increased from 5 to 8 to 10 cmH2O, and then decreased to 8 cmH2O and returned to baseline CDP...
August 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28507580/impact-of-antenatal-oxytocin-infusion-on-neonatal-respiratory-morbidity-associated-with-elective-cesarean-section
#17
Ibrahim Abdelazim, Mohamed M M Farghali, Assem A M Elbiaa, Khaled M Abdelrazak, Mohamed Hussain, Amr H Yehia, Mona Rashad
INTRODUCTION: This study was designed to estimate respiratory morbidity associated with elective cesarean section (ECS) and to determine the effect of antenatal oxytocin exposure on this morbidity. MATERIAL AND METHODS: Nine hundred and sixty-five neonates ≥ 37 weeks' gestation delivered by cesarean section during 1 year were included in this retrospective study and classified into two groups according to oxytocin exposure before cesarean deliveries. Respiratory morbidity for each group was recorded and statistically analyzed...
April 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28409760/delivery-room-continuous-positive-airway-pressure-and-early-pneumothorax-in-term-newborn-infants
#18
COMPARATIVE STUDY
L Clevenger, J R Britton
OBJECTIVE: To assess the association between delivery room (DR) continuous positive airway pressure (CPAP) and pneumothorax (PT) in term newborns. METHODS: Two studies performed in community hospitals used data extracted from computerized records of term newborns. Infants receiving positive pressure ventilation in the DR were excluded. Tabulated data included receipt of DR CPAP, PT on the day of birth, and gestational age (GA). In a case-control study from 2001-2013, infants with PT were compared to controls without PT but with respiratory distress or hypoxia persisting from birth for receipt of DR CPAP...
2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28304322/endothelin-1-as-a-predictor-marker-for-bronchopulmonary-dysplasia-in-preterm-neonates-with-respiratory-distress-syndrome
#19
M S El Shemi, S Tawfik, S M Khafagy, M T Hamza, A M A Youssef
OBJECTIVE: We aimed to investigate if endothelin 1 concentration at day 3 postnatal age could be used as a predictive marker for development of bronchopulmonary dysplasia in preterm neonates with respiratory distress syndrome. METHODS: This prospective observational study was done on 69 preterm neonates with gestational ages between 28 and 34 weeks and diagnosed as having respiratory distress syndrome. Serum concentrations of endothelin 1 was measured for all patients at day 3 of life and they were divided into BPD and No-BPD groups according to whether they developed bronchopulmonary dysplasia or not...
2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28287810/evaluation-of-initial-respiratory-support-strategies-in-vlbw-neonates-with-rds
#20
Seyyed Abolfazl Afjeh, Mohammad Kazem Sabzehei, Maryam Khoshnood Shariati, Ahmad Reza Shamshiri, Fatemeh Esmaili
BACKGROUND: Non-invasive ventilation (NIV) has brought about a significant change in care and treatment of respiratory distress syndrome (RDS) in very low birth weight (VLBW) neonates. The present study was designed and conducted to evaluate different strategies of initial respiratory support (IRS) in VLBW neonates hospitalized in the neonatal intensive care unit (NICU). METHODS: This prospective study was conducted over three years (March 21, 2011 to March 20, 2014)...
March 2017: Archives of Iranian Medicine
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