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https://www.readbyqxmd.com/read/30103626/chitosan-based-nanoparticles-as-drug-delivery-systems-a-review-on-two-decades-of-research
#1
Sweet Naskar, Ketousetuo Koutsu, Suraj Sharma
Chitosan (CS) is one of the most functional natural biopolymer widely used in the pharmaceutical field due to its biocompatibility and biodegradability. These privileges lead to its application in the synthesis of NPs for the drug during the last two decades. This article gives rise to a general review of the different chitosan nanoparticles (CSNPs) preparation techniques: Ionic gelation, emulsion cross-linking, spray-drying, emulsion-droplet coalescence method, nanoprecipitation, reverse micellar method, desolvation method, modified ionic gelation with radial polymerization and emulsion solvent diffusion, from the point of view of the methodological and mechanistic aspects involved...
August 14, 2018: Journal of Drug Targeting
https://www.readbyqxmd.com/read/30060553/the-pros-and-cons-of-the-use-of-laser-ablation-synthesis-for-the-production-of-silver-nano-antimicrobials
#2
REVIEW
Maria Chiara Sportelli, Margherita Izzi, Annalisa Volpe, Maurizio Clemente, Rosaria Anna Picca, Antonio Ancona, Pietro Mario Lugarà, Gerardo Palazzo, Nicola Cioffi
Silver nanoparticles (AgNPs) are well-known for their antimicrobial effects and several groups are proposing them as active agents to fight antimicrobial resistance. A wide variety of methods is available for nanoparticle synthesis, affording a broad spectrum of chemical and physical properties. In this work, we report on AgNPs produced by laser ablation synthesis in solution (LASiS), discussing the major features of this approach. Laser ablation synthesis is one of the best candidates, as compared to wet-chemical syntheses, for preparing Ag nano-antimicrobials...
July 28, 2018: Antibiotics
https://www.readbyqxmd.com/read/30026127/supercritical-carbon-dioxide-based-technologies-for-the-production-of-drug-nanoparticles-nanocrystals-a-comprehensive-review
#3
REVIEW
Luís Padrela, Miguel A Rodrigues, Andreia Duarte, Ana M A Dias, Mara E M Braga, Hermínio C de Sousa
Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of inadequate drug dissolution rates, is one of the most significant challenges that pharmaceutical companies are currently facing, since this may limit the therapeutic efficacy of marketed drugs, or even result in the discard of potential highly effective drug candidates during developmental stages. Two of the main approaches that have been implemented in recent years to overcome poor drug solubility/dissolution issues have frequently involved drug particle size reduction (i...
July 17, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29984451/metal-organic-framework-derived-materials-progress-and-prospects-for-the-energy-conversion-and-storage
#4
REVIEW
Arindam Indra, Taeseup Song, Ungyu Paik
Exploring new materials with high efficiency and durability is the major requirement in the field of sustainable energy conversion and storage systems. Numerous techniques have been developed in last three decades to enhance the efficiency of the catalyst systems, control over the composition, structure, surface area, pore size, and moreover morphology of the particles. In this respect, metal organic framework (MOF) derived catalysts are emerged as the finest materials with tunable properties and activities for the energy conversion and storage...
July 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29950089/semiconductor-nanomembrane-materials-for-high-performance-soft-electronic-devices
#5
Mikayla A Yoder, Zheng Yan, Mengdi Han, John A Rogers, Ralph G Nuzzo
The development of methods to synthesize and physically manipulate extremely thin, single-crystalline inorganic semiconductor materials, so-called nanomembranes, has led to an almost explosive growth of research worldwide into uniquely enabled opportunities for their use in new "soft" and other unconventional form factors for high-performance electronics. The unique properties that nanomembranes afford, such as their flexibility and lightweight characteristics, allow them to be integrated into electronic and optoelectronic devices that, in turn, adopt these unique attributes...
July 25, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29933223/nano-biosensing-approaches-on-tuberculosis-defy-of-aptamers
#6
REVIEW
Behrouz Golichenari, Rahim Nosrati, Aref Farokhi-Fard, Khalil Abnous, Farzam Vaziri, Javad Behravan
Tuberculosis is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb) complex. According to WHO reports, 53 million TB patients died from 2000 to 2016. Therefore, early diagnosis of the disease is of great importance for global health care programs. The restrictions of traditional methods have encouraged the development of innovative methods for rapid, reliable, and cost-effective diagnosis of tuberculosis. In recent years, aptamer-based biosensors or aptasensors have drawn great attention to sensitive and accessible detection of tuberculosis...
June 11, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29932622/synergetic-transformation-of-solid-inorganic-organic-hybrids-into-advanced-nanomaterials-for-catalytic-water-splitting
#7
Yifu Yu, Yanmei Shi, Bin Zhang
The rational synthesis of advanced nanomaterials with well-defined structures has been intensively studied due to the remarkable properties and intriguing applications of the formed materials. Recently, inorganic-organic hybrids have been widely adopted as precursors for chemical transformations toward the preparation of diverse nanomaterials. Specifically, inorganic and organic species with nano/molecule/atom-scale distribution serve as self-templates and sacrificial agents, respectively, endowing the products with controlled morphologies, band gaps, defects, and spatial architectures...
July 17, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29909166/nanoparticle-plant-interaction-implications-in-energy-environment-and-agriculture
#8
REVIEW
Prabhat Kumar Rai, Vanish Kumar, SangSoo Lee, Nadeem Raza, Ki-Hyun Kim, Yong Sik Ok, Daniel C W Tsang
In the recent techno-scientific revolution, nanotechnology has gained popularity at a rapid pace in different sectors and disciplines, specifically environmental, sensing, bioenergy, and agricultural systems. Controlled, easy, economical, and safe synthesis of nanomaterials is desired for the development of new-age nanotechnology. In general, nanomaterial synthesis techniques, such as chemical synthesis, are not completely safe or environmentally friendly due to harmful chemicals used or to toxic by-products produced...
June 14, 2018: Environment International
https://www.readbyqxmd.com/read/29904940/nano-resoles-enabled-elegant-nanostructured-materials
#9
REVIEW
Min Zhang, Yannan Yang, Chengzhong Yu
Since the extension of the Stöber method traditionally used in the synthesis of silica nanoparticles into the fabrication of resorcinol-formaldehyde nanospheres in 2011, significant progresses have been achieved in this exiting area of nano-resole-enabled synthesis of elegant nanostructures with versatile compositions and promising applications in various fields. To date, there are few reviews focused on this topic. In this minireview, we aim to provide an overview on recent developments, with the emphasis on nano-resoles as an enabling strategy in the synthesis of innovative materials...
June 14, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29892768/single-site-and-nano-confined-photocatalysts-designed-in-porous-materials-for-environmental-uses-and-solar-fuels
#10
REVIEW
Hiromi Yamashita, Kohsuke Mori, Yasutaka Kuwahara, Takashi Kamegawa, Meicheng Wen, Priyanka Verma, Michel Che
Silica-based micro-, meso-, macro-porous materials offer attractive routes for designing single-site photocatalysts, supporting semiconducting nanoparticles, anchoring light-responsive metal complexes, and encapsulating metal nanoparticles to drive photochemical reactions by taking advantage of their large surface area, controllable pore channels, remarkable transparency to UV/vis and tailorable physicochemical surface characteristics. This review mainly focuses on the fascinating photocatalytic properties of silica-supported Ti catalysts from single-site catalysts to nanoparticles, their surface-chemistry engineering, such as the hydrophobic modification and synthesis of thin films, and the fabrication of nanocatalysts including morphology controlled plasmonic nanostructures with localized surface plasmon resonance...
June 12, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29792139/process-intensification-techniques-for-the-production-of-nano-and-submicronic-particles-for-food-and-medical-applications
#11
Marco Stoller, Luca Di Palma, Srikanth Vuppala, Nicola Verdone, Giorgio Vilardi
BACKGROUND: Nowadays, nanoparticles are of great interest for the industry due to their numerous possible applications in several fields. Research on this topic seeks to develop many procedures to produce nanoparticles, mostly at lab scale, batch-wise and with low yield. These procedures generally do not suit industrial needs of continuous, high capacity production. Moreover, the product characteristics require targeting narrow particle size distributions and high quality, which is difficult to achieve by traditional equipment...
May 23, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29774614/photochemistry-for-well-defined-polymers-in-aqueous-media-from-fundamentals-to-polymer-nanoparticles-to-bioconjugates
#12
REVIEW
Kevin M Burridge, Thaiesha A Wright, Richard C Page, Dominik Konkolewicz
This review article highlights recent developments in the field of photochemistry and photochemical reversible deactivation radical polymerization applied to aqueous polymerizations. Photochemistry is a topic of significant interest in the fields of organic, polymer, and materials chemistry because it allows challenging reactions to be performed under mild conditions. Aqueous polymerization is of significant interest because water is an environmentally benign solvent, and the use of water enables complex polymer self-assembly and bioconjugation processes to occur...
June 2018: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29772842/fe-based-nano-materials-in-catalysis
#13
REVIEW
Stavros Alexandros Theofanidis, Vladimir V Galvita, Christos Konstantopoulos, Hilde Poelman, Guy B Marin
The role of iron in view of its further utilization in chemical processes is presented, based on current knowledge of its properties. The addition of iron to a catalyst provides redox functionality, enhancing its resistance to carbon deposition. FeOx species can be formed in the presence of an oxidizing agent, such as CO₂, H₂O or O₂, during reaction, which can further react via a redox mechanism with the carbon deposits. This can be exploited in the synthesis of active and stable catalysts for several processes, such as syngas and chemicals production, catalytic oxidation in exhaust converters, etc...
May 17, 2018: Materials
https://www.readbyqxmd.com/read/29772760/a-review-of-carbon-nanomaterials-synthesis-via-the-chemical-vapor-deposition-cvd-method
#14
REVIEW
Yehia M Manawi, Ayman Samara, Tareq Al-Ansari, Muataz A Atieh
Carbon nanomaterials have been extensively used in many applications owing to their unique thermal, electrical and mechanical properties. One of the prime challenges is the production of these nanomaterials on a large scale. This review paper summarizes the synthesis of various carbon nanomaterials via the chemical vapor deposition (CVD) method. These carbon nanomaterials include fullerenes, carbon nanotubes (CNTs), carbon nanofibers (CNFs), graphene, carbide-derived carbon (CDC), carbon nano-onion (CNO) and MXenes...
May 17, 2018: Materials
https://www.readbyqxmd.com/read/29707894/advancements-in-copper-nanowires-synthesis-purification-assemblies-surface-modification-and-applications
#15
REVIEW
Songfang Zhao, Fei Han, Jinhui Li, Xiangying Meng, Wangping Huang, Duxia Cao, Guoping Zhang, Rong Sun, Ching-Ping Wong
Copper nanowires (CuNWs) are attracting a myriad of attention due to their preponderant electric conductivity, optoelectronic and mechanical properties, high electrocatalytic efficiency, and large abundance. Recently, great endeavors are undertaken to develop controllable and facile approaches to synthesize CuNWs with high dispersibility, oxidation resistance, and zero defects for future large-scale nano-enabled materials. Herein, this work provides a comprehensive review of current remarkable advancements in CuNWs...
June 2018: Small
https://www.readbyqxmd.com/read/29707879/recent-advances-in-polyanhydride-based-biomaterials
#16
REVIEW
Arijit Basu, Abraham J Domb
This review focusses on recent developments of polyanhydrides, a class of degradable synthetic biopolymers. Polyanhydrides have been used as carriers for controlled delivery of drugs. A polyanhydride copolymer of carboxyphenoxy propane and sebacic acid has been used in Gliadel brain tumor implants for the controlled delivery of carmustine or bis-chloroethylnitrosourea. They are easy and inexpensive to synthesize (especially scale up). However, polyanhydrides possess a short shelf-life. Hydrolytic cleavage and anhydride interchanges lower their molecular weights during storage...
April 30, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29653217/customizing-poly-lactic-co-glycolic-acid-particles-for-biomedical-applications
#17
REVIEW
Edyta Swider, Olga Koshkina, Jurjen Tel, Luis J Cruz, I Jolanda M de Vries, Mangala Srinivas
Nano- and microparticles have increasingly widespread applications in nanomedicine, ranging from drug delivery to imaging. Poly(lactic-co-glycolic acid) (PLGA) particles are the most widely-applied type of particles due to their biocompatibility and biodegradability. Here, we discuss the preparation of PLGA particles, and various modifications to tailor particles for applications in biological systems. We highlight new preparation approaches, including microfluidics and PRINT method, and modifications of PLGA particles resulting in novel or responsive properties, such as Janus or upconversion particles...
June 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29626551/microfluidics-in-nanoparticle-drug-delivery-from-synthesis-to-pre-clinical-screening
#18
REVIEW
Jungho Ahn, Jihoon Ko, Somin Lee, James Yu, YongTae Kim, Noo Li Jeon
Microfluidic technologies employ nano and microscale fabrication techniques to develop highly controllable and reproducible fluidic microenvironments. Utilizing microfluidics, lead compounds can be produced with the controlled physicochemical properties, characterized in a high-throughput fashion, and evaluated in in vitro biomimetic models of human organs; organ-on-a-chip. As a step forward from conventional in vitro culture methods, microfluidics shows promise in effective preclinical testing of nanoparticle-based drug delivery...
March 15, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29611588/capillary-assembly-as-a-tool-for-the-heterogeneous-integration-of-micro-and-nanoscale-objects
#19
REVIEW
Songbo Ni, Lucio Isa, Heiko Wolf
During the past decade, capillary assembly in topographical templates has evolved into an efficient method for the heterogeneous integration of micro- and nano-scale objects on a variety of surfaces. This assembly route has been applied to a large spectrum of materials of micrometer to nanometer dimensions, supplied in the form of aqueous colloidal suspensions. Using systems produced via bulk synthesis affords a huge flexibility in the choice of materials, holding promise for the realization of novel superior devices in the fields of optics, electronics and health, if they can be integrated into surface structures in a fast, simple, and reliable way...
April 25, 2018: Soft Matter
https://www.readbyqxmd.com/read/29611485/diversity-oriented-synthesis-of-4h-pyrimido-2-1-b-benzothiazole-derivatives-via-biginellis-reaction-a-review
#20
Divyani Gandhi, Priyanka Kalal, Prakash Prajapat, Dinesh Kumar Agarwal, Shikha Agarwal
BACKGROUND: Heterocycles have extended into widespread use for generating large collection of molecules in multi-component reactions. The development of new strategies for fused pyrimidobenzothiazole system has remained a highly attractive but challenging proposition for scientists working all around. OBJECTIVE: The main objective of this work is to explore the utility of different catalysts as an ecofriendly reaction medium for green Biginellis reaction. METHOD: A detailed study of Biginellis reactions using various catalysts was done using different research tools...
2018: Combinatorial Chemistry & High Throughput Screening
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