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https://www.readbyqxmd.com/read/29227263/-adaptive-regulatory-mechanisms-of-alopecia-areata
#1
L Bolotnaja, I Serbina
Failure of adaptive mechanisms leads to structural and functional damage at all levels and of neuroendocrinal and immune systems, which are pathogenetic basis of development of autoimmune diseases, in particular. The objective of this work was to assess the condition of adaptive hormones, such as cortisol and insulin, coefficient of stress of adaptive potential "K" and also dermatologic life quality index (DLQI) of the diseased with alopecia areata (AA). 48 patients with different forms of AA aged between 18 and 52 were examined...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29226590/dheas-patterning-across-childhood-in-three-sub-saharan-populations-associations-with-age-sex-ethnicity-and-cortisol
#2
Courtney Helfrecht, Edward H Hagen, David DeAvila, Robin M Bernstein, Samuel J Dira, Courtney L Meehan
OBJECTIVES: Hormones have many roles in human ontogeny, including the timing of life history 'switch points' across development. Limited hormonal data exist from non-Western children, leaving a significant gap in our understanding of the diversity of life history patterning. This cross-sectional study examines dehydroepiandrosterone sulfate (DHEAS) production in relation to age, sex, ethnicity, and cortisol concentrations, as well as average age of adrenarche, among Aka and Ngandu children of the Central African Republic and Sidama children of Ethiopia...
December 11, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29199102/effect-of-repeated-adrenocorticotropic-hormone-administration-on-reproductive-function-and-hair-cortisol-concentration-during-the-estrous-cycle-in-goats
#3
Natsumi Endo, Hiroaki Yamane, Larasati Puji Rahayu, Tomomi Tanaka
Measurement of the cortisol concentration in hair has been used as an index of chronic stress in several species including humans, wildlife and domestic animals. However, how accurately the cortisol concentration in hair reflects the changes in circulating cortisol concentrations has not been well documented. The objective of the present study was to examine the effect of repeated adrenocorticotropic hormone (ACTH) administration on the reproductive function during the estrous cycle and hair cortisol concentrations in goats...
November 30, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29180003/correlations-of-hair-level-with-salivary-level-in-cortisol-and-cortisone
#4
Quan Zhang, Zheng Chen, Shenghuo Chen, Tian Yu, Juxia Wang, Weiwen Wang, Huihua Deng
AIMS: Contrary findings exist on the consistency between hair cortisol and salivary cortisol in assessing the basal activity of the hypothalamic-pituitary-adrenal (HPA) axis. The mismatches in temporal characteristic and the indices of hair and salivary cortisol might be potential reasons for the inconsistency. The aim of this study was to investigate the consistency between hair and salivary levels in cortisol and cortisone by directly examining the correlation between hair level and salivary level with different temporal characteristics (acute, short-term and long-term levels) and reflecting different HPA functions (basal level and reactivity level) in the well-matched time span...
November 24, 2017: Life Sciences
https://www.readbyqxmd.com/read/29162166/shaping-long-term-primate-development-telomere-length-trajectory-as-an-indicator-of-early-maternal-maltreatment-and-predictor-of-future-physiologic-regulation
#5
Stacy S Drury, Brittany R Howell, Christopher Jones, Kyle Esteves, Elyse Morin, Reid Schlesinger, Jerrold S Meyer, Kate Baker, Mar M Sanchez
The molecular, neurobiological, and physical health impacts of child maltreatment are well established, yet mechanistic pathways remain inadequately defined. Telomere length (TL) decline is an emerging molecular indicator of stress exposure with definitive links to negative health outcomes in maltreated individuals. The multiple confounders endemic to human maltreatment research impede the identification of causal pathways. This study leverages a unique randomized, cross-foster, study design in a naturalistic translational nonhuman primate model of infant maltreatment...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29154569/the-social-transmission-of-risk-maternal-stress-physiology-synchronous-parenting-and-well-being-mediate-the-effects-of-war-exposure-on-child-psychopathology
#6
Galit Halevi, Amir Djalovski, Yaniv Kanat-Maymon, Karen Yirmiya, Orna Zagoory-Sharon, Lee Koren, Ruth Feldman
While chronic early stress increases child susceptibility to psychopathology, risk and resilience trajectories are shaped by maternal social influences whose role requires much further research in longitudinal studies. We examined the social transmission of risk by assessing paths leading from war-exposure to child symptoms as mediated by 3 sources of maternal social influence; stress physiology, synchronous parenting, and psychiatric disorder. Mothers and children living in a zone of continuous war were assessed in early childhood (1...
November 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/29127340/hair-cortisol-in-twins-heritability-and-genetic-overlap-with-psychological-variables-and-stress-system-genes
#7
Liz Rietschel, Fabian Streit, Gu Zhu, Kerrie McAloney, Josef Frank, Baptiste Couvy-Duchesne, Stephanie H Witt, Tina M Binz, John McGrath, Ian B Hickie, Narelle K Hansell, Margaret J Wright, Nathan A Gillespie, Andreas J Forstner, Thomas G Schulze, Stefan Wüst, Markus M Nöthen, Markus R Baumgartner, Brian R Walker, Andrew A Crawford, Lucía Colodro-Conde, Sarah E Medland, Nicholas G Martin, Marcella Rietschel
Hair cortisol concentration (HCC) is a promising measure of long-term hypothalamus-pituitary-adrenal (HPA) axis activity. Previous research has suggested an association between HCC and psychological variables, and initial studies of inter-individual variance in HCC have implicated genetic factors. However, whether HCC and psychological variables share genetic risk factors remains unclear. The aims of the present twin study were to: (i) assess the heritability of HCC; (ii) estimate the phenotypic and genetic correlation between HPA axis activity and the psychological variables perceived stress, depressive symptoms, and neuroticism; using formal genetic twin models and molecular genetic methods, i...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29112905/determinants-of-hair-cortisol-concentration-in-children-a-systematic-review
#8
REVIEW
N A Gray, A Dhana, L Van Der Vyver, J Van Wyk, N P Khumalo, D J Stein
BACKGROUND: Several factors are known contribute to hair cortisol concentration (HCC) in adults. However, there is less research on determinants of HCC in children and adolescents. HCC is a valuable tool for medical research pertaining to the hypothalamic-pituitary-adrenal (HPA) axis. This review aims to assess the extent to which established determinants of HCC in adults have been consistently reported in children (birth - 18 years) and to identify determinants of HCC specific to this age group...
November 2, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29108039/effect-of-band-and-knife-castration-of-beef-calves-on-welfare-indicators-of-pain-at-three-relevant-industry-ages-ii-chronic-pain
#9
S Marti, D M Meléndez, E A Pajor, D Moya, C E M Heuston, D Gellatly, E D Janzen, K S Schwartzkopf-Genswein
Three experiments were conducted to evaluate the effects of band and knife castration on behavioral and physiological indicators of chronic pain in beef calves at 3 different ages (36 calves/age group): 1 wk of age (Exp. 1, 4 ± 1.1 d of age, 43 ± 1.1 kg BW), 2 mo of age (Exp. 2, 63 ± 2.3 d of age, 92 ± 1.7 kg BW), and 4 mo of age (Exp. 3, 125 ± 4.6 d of age, 160 ± 3.4 kg BW). In each experiment calves were randomly assigned to either sham (CT), band (BA) or knife (KN) castration. Experiments 1, 2, and 3 ended when the testicles of banded calves had sloughed off (68, 49, and 42 d, respectively)...
October 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/29073819/evaluation-of-hair-cortisol-and-cortisone-change-during-pregnancy-and-the-association-with-self-reported-depression-somatization-and-stress-symptoms
#10
Friederike Scharlau, Diana Pietzner, Mandy Vogel, Alexander Gaudl, Uta Ceglarek, Joachim Thiery, Jürgen Kratzsch, Andreas Hiemisch, Wieland Kiess
Hair cortisol levels are used to measure long-term stress, while its inactive metabolite cortisone is often not assessed. We measured hair cortisol concentrations (HCC) and hair cortisone concentrations (HCNC) via liquid chromatography quadrupole linear ion trap mass spectrometry (LC-MS(3)) in 62 pregnant women who participated in the LIFE CHILD STUDY in their 2nd and 3rd trimester between 12/2011 and 11/2014. Sociodemographic factors, pregnancy-related factors, and hair characteristics were assessed. Degree of severity of depression, somatization, and stress were evaluated in both trimesters with a self-reported Patient Health Questionnaire (PHQ)...
October 26, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29065770/salivary-cortisol-reactivity-in-preschoolers-is-associated-with-hair-cortisol-and-behavioral-problems
#11
Katie Kao, Stacey N Doan, Ashley M St John, Jerrold S Meyer, Amanda R Tarullo
The interplay between children's cortisol reactivity to challenge and cumulative cortisol exposure is not well understood. Examining the role of cortisol reactivity in early childhood may elucidate biological mechanisms that contribute to children's chronic physiological stress and behavioral dysregulation. In a sample of 65 preschool-aged children, we examined the relation between children's salivary cortisol reactivity to challenging tasks and their hair cortisol concentration (HCC). While both are biomarkers of the hypothalamic-pituitary-adrenal (HPA) axis, salivary cortisol reactivity reflects an acute cortisol response to a stressor and HCC reflects cumulative cortisol exposure...
October 24, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29047245/11%C3%AE-hydroxysteroid-dehydrogenase-type-1-inhibition-attenuates-the-adverse-effects-of-glucocorticoids-on-dermal-papilla-cells
#12
Sang Eun Lee, Eun Young Lee, Sang Jin Kang, Seung Hun Lee
PURPOSE: Glucocorticoids, stress-related hormones, inhibit hair growth. Intracellular glucocorticoid availability is regulated by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). 11β-HSD1 was recently detected in keratinocytes and fibroblasts. However, the expression of 11β-HSD1 in human hair follicles remains unknown. We aimed to examine 11β-HSD1 expression in human dermal papilla cells (DPCs) and to investigate whether modulation of 11β-HSD1 activity can regulate the negative effects of glucocorticoids on DPCs...
November 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29033885/emotions-and-steroid-secretion-in-aging-men-a-multi-study-report
#13
Andreas Walther, Patricia Waldvogel, Emilou Noser, Jessica Ruppen, Ulrike Ehlert
Although aging increases the risk of cognitive and socioemotional deterioration, it has also been shown to be accompanied by an increase in experienced positive emotions and a decrease in negative emotions. Steroid hormones and age-related alterations in secretion patterns have been suggested to play a crucial role in these age-related changes in emotional experience. Importantly, previous studies identified effects of neuroactive hormones on age-related alterations in emotional experience, which vary by sex and depression levels...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28994168/hair-cortisol-levels-of-lactating-dairy-cows-in-cold-and-warm-temperate-regions-in-japan
#14
Katsuji Uetake, Shigeru Morita, Nobutada Sakagami, Kazuaki Yamamoto, Shinji Hashimura, Toshio Tanaka
We compared the hair cortisol levels of lactating dairy cows in a cold- and a warm-temperate region out of four climatic zones in Japan. We simultaneously investigated the effects of calving number, lactation period and month of hair sampling. Hair of nine Holstein lactating cows chosen from each region (i.e. 18 cows per sampling) was sampled in March, June, September and December. Number of calvings (1, 2, ≥3) and lactation duration (early: <100, middle: 101-200, and late: >201 days) were balanced between regions...
October 9, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28983193/maternal-lifetime-trauma-exposure-prenatal-cortisol-and-infant-negative-affectivity
#15
Michelle Bosquet Enlow, Katrina L Devick, Kelly J Brunst, Lianna R Lipton, Brent A Coull, Rosalind J Wright
Little research has examined the impact of maternal lifetime trauma exposure on infant temperament. We examined associations between maternal trauma history and infant negative affectivity and modification by prenatal cortisol exposure in a sociodemographically diverse sample of mother-infant dyads. During pregnancy, mothers completed measures of lifetime trauma exposure and current stressors. Third-trimester cortisol output was assessed from maternal hair. When infants were 6 months old, mothers completed the Infant Behavior Questionnaire-Revised...
July 2017: Infancy: the Official Journal of the International Society on Infant Studies
https://www.readbyqxmd.com/read/28969697/evaluation-of-a-randomized-controlled-trial-on-the-effect-on-return-to-work-with-coaching-combined-with-light-therapy-and-pulsed-electromagnetic-field-therapy-for-workers-with-work-related-chronic-stress
#16
Karen Nieuwenhuijsen, Antonius M C Schoutens, Monique H W Frings-Dresen, Judith K Sluiter
BACKGROUND: Chronic work-related stress is quite prevalent in the working population and is in some cases accompanied by long-term sick leave. These stress complaints highly impact employees and are costly due to lost productivity and medical expenses. A new treatment platform with light therapy plus Pulsed Electro Magnetic Fields (PEMF) in combination with coaching was used to assess whether more positive effects on return to work, stress, work-related fatigue, and quality of life could be induced compared to coaching alone...
October 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28963625/long-distance-transport-of-hair-lambs-effect-of-location-in-pot-belly-trailers-on-thermo-physiology-welfare-and-meat-quality
#17
G C Miranda-de la Lama, M Rodríguez-Palomares, R G Cruz-Monterrosa, A A Rayas-Amor, R S B Pinheiro, F M Galindo, M Villarroel
Livestock transport exposes animals to a range of potential stressors that may compromise their welfare and final product quality, and those effects typically increase with the distance travelled. In North America, producers often use pot-belly vehicles for long hauls but little is known about their suitability for transporting lambs. We followed two long-distance trips using pot-belly trailers carrying 500 lambs (each) from Northern to Central Mexico in winter, to measure possible effects on animal welfare and meat quality...
September 30, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28957772/assessment-of-brain-derived-neurotrophic-factor-in-hair-to-study-stress-responses-a-pilot-investigation
#18
H Harb, M González-de-la-Vara, L Thalheimer, U Klein, H Renz, M Rose, J Kruse, D P Potaczek, E M J Peters
To study pathogenic stress-effects in health and disease, it is paramount to define easy access parameters for non-invasive analysis of biological change in response to stress. Hair samples successfully provide this access for the study of hypothalamus-pituitary-adrenal axis (HPA) changes. In this study, we assess the hair expression and corresponding epigenetic changes of a neurotrophin essential for autonomic nervous system function and mental health: brain derived neurotrophic factor (BDNF). In three independent studies in healthy academic volunteers (study I: German students, N=36; study II, German academic population sample, N=28; study III: Mexican students, N=115), BDNF protein expression or BDNF gene (BDNF) histone acetylation was determined...
December 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28955159/comparison-of-physical-body-growth-and-metabolic-and-reproductive-endocrine-functions-between-north-and-south-climates-of-japan-in-trained-thoroughbred-yearling-horses
#19
Siriwan Tangyuenyong, Fumio Sato, Yasuo Nambo, Harutaka Murase, Yoshiro Endo, Tomomi Tanaka, Kentaro Nagaoka, Gen Watanabe
This study aimed to compare body growth, metabolic, and reproductive hormonal changes in trained Thoroughbred yearling horses under different climate conditions with and without light supplementation (LS). Thoroughbred yearlings raised at research centers of the Japan Racing Association in Hokkaido (north) or Miyazaki (south) were divided into control and LS groups. In the LS groups, 44 colts and 47 fillies from Hokkaido and 11 colts and 11 fillies from Miyazaki were exposed to LS with an extended photoperiod of 14...
2017: Journal of Equine Science
https://www.readbyqxmd.com/read/28954736/interpretation-of-glucocorticoids-in-neonatal-hair-a-reflection-of-intrauterine-glucocorticoid-regulation
#20
Jonneke J Hollanders, Bibian van der Voorn, Noera Kieviet, Koert M Dolman, Yolanda B de Rijke, Erica L T van den Akker, Joost Rotteveel, Adriaan Honig, Martijn J J Finken
BACKGROUND: Glucocorticoids (GCs) measured in neonatal hair might reflect intrauterine as well as postpartum GC regulation. We aimed to identify factors associated with neonatal hair GC levels in early life, and their correlation with maternal hair GCs. METHODS: In a single-center observational study, mother-infant pairs (n = 107) admitted for >72 h at the maternity ward of a general hospital were included. At birth and an outpatient visit (OPV, n = 72, 44 ± 11 days postpartum), maternal and neonatal hair was analyzed for cortisol and cortisone levels by LC-MS/MS...
November 2017: Endocrine Connections
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