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Hair cortisol

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https://www.readbyqxmd.com/read/28229550/hair-cortisol-and-adiposity-in-a-population-based-sample-of-2-527-men-and-women-aged-54-to-87-years
#1
Sarah E Jackson, Clemens Kirschbaum, Andrew Steptoe
OBJECTIVE: Chronic cortisol exposure is hypothesized to contribute to obesity. This study examined associations between hair cortisol concentrations, a novel indicator of long-term cortisol exposure, and adiposity in a large population-based sample. METHODS: Data were from 2,527 men and women aged 54 and older (98% white British) participating in the English Longitudinal Study of Ageing. Hair cortisol concentrations were determined from the scalp-nearest 2 cm hair segment, and height, weight, and waist circumference were objectively measured...
March 2017: Obesity
https://www.readbyqxmd.com/read/28203534/comparison-of-methanol-and-isopropanol-as-wash-solvents-for-determination-of-hair-cortisol-concentration-in-grizzly-bears-and-polar-bears
#2
Thomas Kroshko, Luciene Kapronczai, Marc R L Cattet, Bryan J Macbeth, Gordon B Stenhouse, Martyn E Obbard, David M Janz
Methodological differences among laboratories are recognized as significant sources of variation in quantification of hair cortisol concentration (HCC). An important step in processing hair, particularly when collected from wildlife, is the choice of solvent used to remove or "wash" external hair shaft cortisol prior to quantification of HCC. The present study systematically compared methanol and isopropanol as wash solvents for their efficiency at removing external cortisol without extracting internal hair shaft cortisol in samples collected from free-ranging grizzly bears and polar bears...
2017: MethodsX
https://www.readbyqxmd.com/read/28199857/socioeconomic-status-hair-cortisol-and-internalizing-symptoms-in-parents-and-children
#3
Alexandra Ursache, Emily C Merz, Samantha Melvin, Jerrold Meyer, Kimberly G Noble
Socioeconomic disadvantage is consistently linked with higher risk for internalizing problems, and stress is likely one important mechanism explaining this increased risk. Few studies have examined socioeconomic differences in hair cortisol, a novel biomarker of long-term adrenocortical activity and chronic stress. Moreover, no studies have examined whether differences in hair cortisol might explain socioeconomic disparities in internalizing problems. To address these gaps, we first examined relations of socioeconomic status (SES; family income and parental education) to variation in both parents' and children's hair cortisol concentrations (HCC) and then tested whether HCC and perceptions of stress mediated relations of SES to parents' and children's internalizing symptoms...
January 28, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28194652/hair-cortisol-in-the-evaluation-of-cushing-syndrome
#4
Aaron Hodes, Maya B Lodish, Amit Tirosh, Jerrold Meyer, Elena Belyavskaya, Charalampos Lyssikatos, Kendra Rosenberg, Andrew Demidowich, Jeremy Swan, Nichole Jonas, Constantine A Stratakis, Mihail Zilbermint
PURPOSE: Hair cortisol evaluation has been used to help detect patients with suspected Cushing syndrome. Our goal was to correlate segmental hair cortisol with biochemical testing in patients with Cushing syndrome and controls. This study was a prospective analysis of hair cortisol in confirmed Cushing syndrome cases over 16 months. METHODS: Thirty-six subjects (26.5 ± 18.9 years, 75% female, and 75% Caucasian) were analyzed by diurnal serum cortisol, 24 h urinary free cortisol corrected for body surface area (UFC/BSA), and 24 h urinary 17-hydroxysteroids corrected for creatinine (17OHS/Cr)...
February 13, 2017: Endocrine
https://www.readbyqxmd.com/read/28177361/effects-of-temperament-on-physiological-productive-and-reproductive-responses-in-beef-cows
#5
R F Cooke, K M Schubach, R S Marques, R F G Peres, L G T Silva, R S Carvalho, R S Cipriano, D W Bohnert, A V Pires, J L M Vasconcelos
This experiment evaluated the effects of temperament on physiological, productive, and reproductive responses in beef cows. A total of 953 lactating, multiparous, non-pregnant Nelore cows (age = 99 ± 2 mo; days post-partum = 51.4 ± 0.3 d; BCS = 5.34 ± 0.04; BW = 430 ± 2 kg) were allocated into 8 groups of approximately 120 cows each. Groups were assigned to an estrus synchronization + timed-AI protocol at the beginning of the breeding season. Concurrently with AI, blood samples were collected, hair samples were clipped from the tail switch, and cow temperament was evaluated via chute score and exit velocity...
January 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28135675/blunted-hpa-axis-activity-prior-to-suicide-attempt-and-increased-inflammation-in-attempters
#6
Nadine M Melhem, Sara Munroe, Anna Marsland, Katarina Gray, David Brent, Giovanna Porta, Antoine Douaihy, Mark L Laudenslager, Frank DePietro, Rasim Diler, Henry Driscoll, Priya Gopalan
BACKGROUND: Hypothalamic-Pituitary-Adrenal (HPA) axis dysregulation is associated with increased risk for suicidal behavior. However, it is not clear whether such dysregulation exists prior to or is a consequence of attempt. Studies also show an activation of inflammatory responses in suicidal behavior but often combine attempters with those with ideation. METHODS: The sample consisted of psychiatric inpatients, aged 15-30 years, admitted for suicide attempt (SA, n=38), inpatients admitted for suicidal ideation with no prior history of attempts (SI, n=40), and healthy controls (n=37)...
January 10, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28135674/stress-related-and-basic-determinants-of-hair-cortisol-in-humans-a-meta-analysis
#7
REVIEW
Tobias Stalder, Susann Steudte-Schmiedgen, Nina Alexander, Tim Klucken, Annika Vater, Susann Wichmann, Clemens Kirschbaum, Robert Miller
The analysis of hair cortisol concentrations (HCC) is a relatively new strategy to measure long-term cumulative cortisol levels, which is increasingly used in psychoneuroendocrinological research. Here, we conduct a first comprehensive meta-analysis of HCC research based on aggregated data from a total of 124 (sub)samples (66 independent studies; total N=10,289). We seek to answer two central questions: (i) Which covariates and basic features of HCC need to be considered in future research? (ii) What are the main determinants of HCC in terms of chronic stress exposure and mental health? Concerning basic characteristics, our findings identify several covariates to be considered (age, sex, hair washing frequency, hair treatment, oral contraceptive use), confirm a decline of HCC from the first to the second proximal 3cm hair segment, and show positive associations between HCC and short-term salivary cortisol measures...
January 10, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28122298/stress-vulnerability-in-male-youth-with-internet-gaming-disorder
#8
Michael Kaess, Peter Parzer, Laura Mehl, Luisa Weil, Esther Strittmatter, Franz Resch, Julian Koenig
Internet Gaming Disorder [IGD] was introduced as new behavioral addiction in DSM-5 Section 3. Vulnerability to stress is a potential predisposing factor for IGD. Given a lack of preexisting empirical data, the study investigated differences in the psychological and neurobiological response to acute stress in patients with IGD. 24 young men (mean age 18.38 years; range 13-25 years) fulfilling DSM-5 criteria for IGD and 25 matched controls underwent the Trier Social Stress Test [TSST]. Participants provided hair samples for the analysis of basal hypothalamic-pituitary-adrenal [HPA] axis activity and clinical interviews were conducted to assess psychopathology...
January 10, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28109728/the-utility-of-hair-cortisol-concentrations-in-the-prediction-of-ptsd-symptoms-following-traumatic-physical-injury
#9
Maria L Pacella, Bryce Hruska, Susann Steudte-Schmiedgen, Richard L George, Douglas L Delahanty
RATIONALE: Although cortisol alterations have been associated with posttraumatic stress disorder (PTSD) and PTSD symptoms (PTSS), the direction of association is mixed. Cortisol which is measured in blood, saliva, or urine is subject to transient factors that may confound results. Recent advances in cortisol sampling techniques provide novel opportunities to address these inconsistencies. Hair cortisol sampling is a non-invasive method for the retrospective assessment of long-term integrated cortisol, yet its utility at predicting PTSS has not been assessed in acute injury victims...
January 6, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28107896/cortisol-levels-in-hair-are-altered-in-irritable-bowel-syndrome-a-case-control-study-in-primary-care
#10
A-K Norlin, S Walter, E Theodorsson, V Tegelstrom, E Grodzinsky, M P Jones, Å Faresjö
OBJECTIVE: Stress is an important component in the pathophysiology of irritable bowel syndrome (IBS). Long term Hypothalamus Pituitary Adrenal (HPA)-axis activity can be studied by measuring hair cortisol concentrations (HCC). Some previous studies have indicated a dysregulated HPA-axis in IBS patients, but cortisol levels in hair have not yet been studied. We investigated whether HCC and self-reported stress differentiate IBS patients from controls. METHODS: In a cross-sectional study within 10 Swedish Primary Health Care Centers we compared patients in working age with active IBS to patients without GI complaints...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28105726/biological-stress-indicators-as-risk-markers-for-increased-alcohol-use-following-traumatic-experiences
#11
Sebastian Trautmann, Markus Muehlhan, Clemens Kirschbaum, Hans-Ulrich Wittchen, Michael Höfler, Tobias Stalder, Susann Steudte-Schmiedgen
Alcohol misuse is a common sequela of traumatic event experiences causing considerable morbidity and mortality. Although biological stress indicators have been identified as useful risk markers for the development of trauma-related disorders, no such biological indicators exist for the risk of increased alcohol use after trauma exposure. This is the first study to prospectively investigate the predictive value of long-term cortisol levels and acute stress reactivity for the risk of increased alcohol use following traumatic events...
January 20, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28100283/genetic-influences-on-hormonal-markers-of-chronic-hypothalamic-pituitary-adrenal-function-in-human-hair
#12
E M Tucker-Drob, A D Grotzinger, D A Briley, L E Engelhardt, F D Mann, M Patterson, C Kirschbaum, E K Adam, J A Church, J L Tackett, K P Harden
BACKGROUND: Cortisol is the primary output of the hypothalamic-pituitary-adrenal (HPA) axis and is central to the biological stress response, with wide-ranging effects on psychiatric health. Despite well-studied biological pathways of glucocorticoid function, little attention has been paid to the role of genetic variation. Conventional salivary, urinary and serum measures are strongly influenced by diurnal variation and transient reactivity. Recently developed technology can be used to measure cortisol accumulation over several months in hair, thus indexing chronic HPA function...
January 19, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28095431/hair-measurements-of-cortisol-dhea-and-dhea-to-cortisol-ratio-as-biomarkers-of-chronic-stress-among-people-living-with-hiv-in-china-known-group-validation
#13
Shan Qiao, Xiaoming Li, Samuele Zilioli, Zheng Chen, Huihua Deng, Juxian Pan, Weigui Guo
BACKGROUND: Existing literature suggests that endocrine measures, including the steroid hormones of cortisol and Dehydroepiandrosterone (DHEA), as well as the DHEA to cortisol ratio in the human hair can be used as promising biomarkers of chronic stress among humans. However, data are limited regarding the validity of these measures as biomarkers of chronic stress among people living with HIV (PLWH), whose endocrine system or hypothalamic pituitary adrenal (HPA) axis may be affected by HIV infection and/or antiretroviral therapy (ART) medications...
2017: PloS One
https://www.readbyqxmd.com/read/28089708/hair-corticosterone-measurement-in-mouse-models-of-type-1-and-type-2-diabetes-mellitus
#14
Rebecca L Erickson, Caroline A Browne, Irwin Lucki
In diabetes, glucocorticoid secretion increases secondary to hyperglycemia and is associated with an extensive list of disease complications. Levels of cortisol in humans, or corticosterone in rodents, are usually measured as transitory biomarkers of stress in blood or saliva. Glucocorticoid concentrations accumulate in human or animal hair over weeks and could more accurately measure the cumulative stress burden of diseases like chronic diabetes. In this study, corticosterone levels were measured in hair in verified rodent models of diabetes mellitus...
January 12, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28073090/hair-dyeing-hair-washing-and-hair-cortisol-concentrations-among-women-from-the-healthy-start-study
#15
Sheila K Kristensen, Sofus C Larsen, Nanna J Olsen, Jan Fahrenkrug, Berit L Heitmann
BACKGROUND: Hair cortisol concentration (HCC) has been suggested as a promising marker for chronic stress. However, studies investigating the influence of hair dyeing and hair washing frequency on HCC have shown inconsistent results. OBJECTIVE: To examine associations between HCC and hair dyeing status or weekly hair washing frequency among women. METHODS: This cross-sectional study was based on data from 266 mothers participating in the Healthy Start intervention study...
December 31, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28064407/hair-cortisol-as-a-marker-of-hypothalamic-pituitary-adrenal-axis-activity-in-female-patients-with-major-depressive-disorder
#16
Ksenia Pochigaeva, Tatiana Druzhkova, Alexander Yakovlev, Mikhail Onufriev, Maria Grishkina, Aleksey Chepelev, Alla Guekht, Natalia Gulyaeva
Hair cortisol is regarded as a promising marker of hypothalamic-pituitary-adrenal axis (HPAA) activity alterations due to stress, somatic and mental health conditions. Hair cortisol was previously reported to be elevated in patients with depression, however the data related to remission and recurrent depressive episodes are different. In this study, levels of hair cortisol were assessed in female patients with major depressive disorder (MDD) and the validity of hair cortisol as a marker of HPAA activity in this condition was evaluated...
January 7, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28050886/evaluation-of-cortisol-and-telomere-length-measurements-in-ethnically-diverse-women-with-breast-cancer-using-culturally-sensitive-methods
#17
Julio Ramirez, May Elmofty, Esperanza Castillo, Mindy DeRouen, Salma Shariff-Marco, Laura Allen, Scarlett Lin Gomez, Anna María Nápoles, Leticia Márquez-Magaña
The under-representation of ethnic minority participants, who are more likely to be socially disadvantaged in biomedical research, limits generalizability of results and reductions in health disparities. To facilitate investigations of how social disadvantage "gets under the skin," this pilot study evaluated low-intensity methods for collecting hair and saliva samples from multiethnic breast cancer survivors (N = 70) and analysis of biomarkers of chronic stress (cortisol levels) and biological age (telomere length)...
January 3, 2017: Journal of Community Genetics
https://www.readbyqxmd.com/read/28043344/relationships-among-temperament-acute-and-chronic-cortisol-and-testosterone-concentrations-and-breeding-soundness-during-performance-testing-of-angus-bulls
#18
S A Lockwood, H G Kattesh, J D Rhinehart, L G Strickland, P D Krawczel, J B Wilkerson, F D Kirkpatrick, A M Saxton
The aim of this study was to examine relationships among temperament, endocrinology, and reproductive parameters of bulls enrolled in an 84-day performance test. Angus bulls (n = 60) were housed in six pens grouped by age and weight. Pen scores (PS; 1 = docile to 5 = very aggressive) were assigned on Days -1, 27, 55, and 83 of the performance test. On the following day, blood and hair samples were collected, and body weight (BW) and exit velocity (EV) were recorded. Bulls were split into two categories based on; Day -1 PS (PScalm = PS 1 or 2; PSexcitable = PS 3 or 4) and Day 0 EV (EVcalm = slowest 20 bulls; EVexcitable = fastest 20 bulls)...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28009336/hypocortisolism-and-preterm-birth
#19
S D Karakash, N Tschankoshvili, J Weedon, R M Schwartz, C Kirschbaum, H Minkoff
OBJECTIVE: We sought to determine whether hypocortisolism is associated with preterm birth, using hair cortisol as a marker of long term hypothalamic-pituitary-adrenal axis activity. STUDY DESIGN: In a prospective, matched, case-control study, 29 women who had a preterm birth at 24-36w5d gestation were compared to 29 women who delivered at term, matched for maternal age, gestational age, and ethnicity. Cases' samples were collected within 72 h of preterm birth and controls at the same gestational age as the corresponding case...
2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27998757/intraindividual-stability-of-cortisol-and-cortisone-and-the-ratio-of-cortisol-to-cortisone-in-saliva-urine-and-hair
#20
Quan Zhang, Zheng Chen, Shenghuo Chen, Youyun Xu, Huihua Deng
BACKGROUND: Cortisol, cortisone and the ratio of cortisol to cortisone in saliva, urine and hair are acute, short-term and long-term biomarkers to reliably assess the activity of hypothalamic-pituitary-adrenal (HPA) axis and 11β-hydroxysteroid dehydrogenase (11β-HSD). One key issue is whether these biomarkers have intraindividual relative stability. Salivary, urinary and hair cortisol was proven to show considerable long-term intraindividual relative stability. However, currently unknown is whether cortisone and the ratio in saliva, urine and hair show intraindividual relative stability...
December 18, 2016: Steroids
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