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Michael Charles Stevens, Fraser M Callaghan, Paul Forrest, Paul G Bannon, Stuart M Grieve
Peripheral veno-arterial extra corporeal membrane oxygenation (VA-ECMO) is an established technique for short-to-medium support of patients with severe cardiac failure. However, in patients with concomitant respiratory failure, the residual native circulation will provide deoxygenated blood to the upper body, and may cause differential hypoxemia of the heart and brain. In this paper, we present a general computational framework for the identification of differential hypoxemia risk in VA-ECMO patients. A range of different VA-ECMO patient scenarios for a patient-specific geometry and vascular resistance were simulated using transient computational fluid dynamics simulations, representing a clinically relevant range of values of stroke volume and ECMO flow...
July 31, 2018: Journal of Biomechanics
Fraser M Callaghan, Paul Bannon, Edward Barin, David Celemajer, Richmond Jeremy, Gemma Figtree, Stuart M Grieve
BACKGROUND: Abnormal flow dynamics play an early and causative role in pathologic changes of the ascending aorta. PURPOSE: To identify: 1) the changes in flow, shape, and size that occur in the ascending aorta with normal human ageing and 2) the influence of these factors on aortic flow dynamics. STUDY TYPE: Retrospective. SUBJECTS: In all, 247 subjects (age range 19-86 years, mean 49 ± 17.7, 169 males) free of aortic or aortic valve pathology were included in this study...
August 13, 2018: Journal of Magnetic Resonance Imaging: JMRI
Tonia M Cassaday
This article discusses the prevalence and timing of perinatal loss. The impact that perinatal grief has on psychological functioning is presented, including common grief reactions and the risk factors for complicated grief. The ways that perinatal grief is processed by each parent and the impact that it has on the relationships is also discussed. The role of the health care professional is outlined and the process for them to assist grieving parents is outlined in 5 steps. The screening process and treatment of grieving parents is also presented...
September 2018: Obstetrics and Gynecology Clinics of North America
Jean Doherty, Sarah Cullen, Brenda Casey, Barbara Lloyd, Lucille Sheehy, Mary Brosnan, Theresa Barry, Anne McMahon, Barbara Coughlan
AIMS: To improve the confidence in student Midwives to provide bereavement careto parents following pregnancy loss and perinatal death. BACKGROUND: The one-day interactive Educational Training Workshop in Bereavement Care (ETWBC) was developed for student midwives in their final year of their B.Sc. Midwifery Degree Programme and those completing a Higher Diploma in Midwifery to help improve their confidence to provide bereavement care in clinical practice. DESIGN: A longitudinal sequential mixed-methods design was used to evaluate the outcome and processes of participation in the Workshop...
July 18, 2018: Midwifery
Marie-Andrée Beaudoin, Nicole Ouellet
INTRODUCTION: Perinatal loss is a complex phenomenon with multiple dimensions and represents a professional challenge for nurses. There are as many different ways of coping with bereavement as there are parents, and nurses must adapt their intervention in order to adequately support grieving parents. PURPOSE: This qualitative study explored the factors that influence nursing practice with bereaved families in a secondary obstetric care center in Quebec. METHODS: Guba and Lincoln's fourth generation evaluation approach was used...
July 12, 2018: Recherche en Soins Infirmiers
Nadin M Abdel Razeq, Ekhlas Al-Gamal
The death of a newborn infant is one of the most devastating situations a mother could experience. The aim of this study was to understand bereavement and its associated meanings as lived and experienced by the mothers who lost their newborn infants in the intensive care units of hospitals in Jordan. Data were generated using semistructured face-to-face interviews with 12 mothers who had the experience. A qualitative phenomenological approach was used for data analysis. Three main themes emerged from the analysis: (1) longing and grieving, as natural emotional responses to the loss; (2) adaptive work of coping, as the mothers internalized meanings to cope with their loss; and (3) moving forward but with a scar, as the mothers moved on with their lives while they carried the unforgettable memories of the newborns' death experience...
April 2018: Journal of Hospice and Palliative Nursing: JHPN
Bettina Grieve, J Baumgartner Lee, Wayne Robinson, Luiz G M Silva, Karl Pomorin, Garry Thorncraft, Nathan Ning
Passive integrated transponder (PIT) tagging has proven to be an effective mark-recapture technique for many temperate freshwater and marine fish species, but its adaptability to tropical freshwater species remains largely unknown. Nevertheless, many tropical river systems, such as the Mekong in South East Asia, are currently being developed at an unprecedented rate for their relatively abundant water resources. Consequently, there is an urgent need for efficient mark-recapture technologies to understand and assess the impacts of human developments on the movement ecology of tropical freshwater fish species...
2018: MethodsX
Lindsay Sheehan, Patrick W Corrigan, Maya A Al-Khouja, Stanley A Lewy, Deborah R Major, Jessica Mead, Megghun Redmon, Charles T Rubey, Stephanie Weber
Many thousands of families lose a loved one to suicide each year. The stigma experienced by family survivors threatens to further burden families and impede the grieving process. This study used a community-based participatory research process to explore the family stigma of suicide from a social-cognitive perspective. We describe a secondary analysis of qualitative data focusing on stigma directed at bereaved families. Thematic analysis of focus group data ( n = 62) resulted in themes describing stereotypes, prejudice, and discrimination...
September 2018: Omega
Hani J Marcus, Abhiney Jain, Joan Grieve, Neil L Dorward
OBJECTIVE: Recent high-profile delict and medical negligence cases now require doctors to take "reasonable care to ensure that the patient is aware of any material risks involved in any recommended treatment, and of any reasonable alternative or variant treatments." To this end, we report the development and evaluation of a procedure-specific online educational resource to support the informed consent process for patients undergoing transsphenoidal excision of pituitary adenoma...
July 19, 2018: World Neurosurgery
Fraser Maurice Callaghan, Stuart Michael Grieve
Wall shear stress (WSS) plays a governing role in vascular remodelling and a pathogenic role in vessel wall diseases. Little however, is known of the normal WSS patterns in the aorta as there is currently no practical means to routinely measure WSS, and no normal ranges derived from population data exist. WSS measurements were made on the aorta of 224 subjects with normal anatomy using 4-dimensional flow MRI (4D-flow) with multiple encoding velocities and an optimized post-processing routine. The spatial and temporal variation in WSS and oscillatory shear index was analyzed using a flat map representation of the unfolded aorta...
July 20, 2018: American Journal of Physiology. Heart and Circulatory Physiology
Renea L Beckstrand, Elise M Corbett, Janelle L B Macintosh, Karlen E Beth Luthy, Ryan J Rasmussen
INTRODUCTION: Although death is common in emergency departments, there is limited research regarding ED design as an obstacle to end-of-life care. This study identifies emergency nurses' recommendations regarding ways designs have negative or positive impact on care for dying patients and their families. METHODS: A 25-item questionnaire was sent to a national random sample of 500 emergency nurses. Inclusion criteria were nurses who could read English, worked in emergency departments, and had cared for at least 1 patient at the end of life (EOL)...
July 12, 2018: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
Michel Paques, Serge Meimon, Florence Rossant, David Rosenbaum, Sarah Mrejen, Florian Sennlaub, Kate Grieve
Adaptive optics (AO)-enhanced en face retinal imaging, termed here AO ophthalmoscopy (AOO) has reached a level of robustness which fuels its increasing use in research and clinical centers. Here we will review the contribution of clinical AOO to the understanding and monitoring of 1) age-related macular degeneration and 2) vascular diseases. The main contributions of AOO to the phenotyping of AMD are a better identification of drusen, a better delineation of the limits of atrophy, and the identification of novel features such as punctate hyperreflectivity and mobile melanin-containing clumps...
July 17, 2018: Progress in Retinal and Eye Research
Chandana Banerjee
No abstract text is available yet for this article.
July 12, 2018: Journal of Pain and Symptom Management
Mark Pennington, Richard Grieve, Jan Van der Meulen, Neil Hawkins
BACKGROUND: Extrapolation of time-to-event data can be a critical component of cost-effectiveness analysis. OBJECTIVES: To contrast the value of external data on treatment effects as a selection aid in model fitting to the clinical data or for the direct extrapolation of survival. METHODS: We assume the existence of external summary data on both treatment and control and consider two scenarios: availability of external individual patient data (IPD) on the control only and an absence of external IPD...
July 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Wenhao Zhang, Mark F Hansen, Melvyn Smith, Lyndon Smith, Bruce Grieve
Leaf venation extraction studies have been strongly discouraged by considerable challenges posed by venation architectures that are complex, diverse and subtle. Additionally, unpredictable local leaf curvatures, undesirable ambient illuminations, and abnormal conditions of leaves may coexist with other complications. While leaf venation extraction has high potential for assisting with plant phenotyping, speciation and modelling, its investigations to date have been confined to colour image acquisition and processing which are commonly confounded by the aforementioned biotic and abiotic variations...
June 2018: Computers in industry
Ian Rivers, Cesar Gonzalez, Nuno Nodin, Elizabeth Peel, Allan Tyler
Evidence suggests that lesbian, gay, bisexual and trans (LGBT) people are more likely to attempt to take their own lives in their youth when compared to heterosexual and/or cisgender people. This study draws on in-depth interviews with 17 LGBT individuals living in England, and explores the narratives used by participants to better understand their perceptions of risk and protective circumstances to explain suicide attempts in youth. Using a Goffman-informed thematic analysis, results identified three key themes that were linked to attempts to end life in youth...
June 30, 2018: Social Science & Medicine
Melissa A Bender, Carol Kummet, Susan Merel
No abstract text is available yet for this article.
July 2018: Journal of Palliative Medicine
Alexina J Mason, Manuel Gomes, Richard Grieve, James R Carpenter
Health economics studies with missing data are increasingly using approaches such as multiple imputation that assume that the data are "missing at random." This assumption is often questionable, as-even given the observed data-the probability that data are missing may reflect the true, unobserved outcomes, such as the patients' true health status. In these cases, methodological guidelines recommend sensitivity analyses to recognise data may be "missing not at random" (MNAR), and call for the development of practical, accessible approaches for exploring the robustness of conclusions to MNAR assumptions...
July 3, 2018: Health Economics
Felicity Agwu Kalu, Barbara Coughlan, Philip Larkin
BACKGROUND: Perinatal bereavement is traumatic for many parents. Not only is the experience itself emotionally painful, the impact on their lives is made more difficult if midwives are unable to provide appropriate care to the parents. AIM OF THE STUDY: To explore within an Irish context, the psychosocial factors that impact on midwives' confidence to provide bereavement support to parents who have experienced a perinatal loss. DESIGN: A mixed methods sequential explanatory design was used to complete this two-phased study from August 2013 to July 2014...
September 2018: Midwifery
Theresa J Allain, Grieves Mang'anda, Marrianne Kasiya, Patricia Khomani, Ndaziona P Banda, Andrew Gonani, Ingrid Peterson, Gavin Dreyer
The Malawian health sector has a strong tradition of systematic data collection for monitoring and evaluation of large-scale services. A highly successful adapted Directly Observed Treatment, Short course "DOTS" framework, based on patient registers and paper-based mastercards was introduced to facilitate the management and monitoring of the scale up of antiretroviral therapy. Subsequently, a simple, touch-screen based electronic medical record system (EMRs) was effectively introduced at high burden ART sites...
December 2017: Malawi Medical Journal: the Journal of Medical Association of Malawi
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