Read by QxMD icon Read

Parkinsons disease and physical therapy

Ryan P Duncan, Linda R Van Dillen, Jane M Garbutt, Gammon M Earhart, Joel S Perlmutter
Background: Subthalamic nucleus deep brain stimulation (STN-DBS) reduces tremor, muscle stiffness, and bradykinesia in people with Parkinson's Disease (PD). Walking speed, known to be reduced in PD, typically improves after surgery; however, other important aspects of gait may not improve. Furthermore, balance may worsen and falls may increase after STN-DBS. Thus, interventions to improve balance and gait could reduce morbidity and improve quality of life following STN-DBS. Physical therapy (PT) effectively improves balance and gait in people with PD, but studies on the effects of PT have not been extended to those treated with STN-DBS...
2018: Pilot and Feasibility Studies
Rebecca L Achey, Erin Yamamoto, Daniel Sexton, Christine Hammer, Bryan S Lee, Robert S Butler, Nicolas R Thompson, Sean J Nagel, Andre G Machado, Darlene A Lobel
OBJECTIVE Deep brain stimulation (DBS) is an effective therapy for movement disorders such as idiopathic Parkinson's disease (PD) and essential tremor (ET). However, some patients who demonstrate benefit on objective motor function tests do not experience postoperative improvement in depression or anxiety, 2 important components of quality of life (QOL). Thus, to examine other possible explanations for the lack of a post-DBS correlation between improved objective motor function and decreased depression or anxiety, the authors investigated whether patient perceptions of motor symptom severity might contribute to disease-associated depression and anxiety...
February 23, 2018: Journal of Neurosurgery
Meng-Fei Sun, Ying-Li Zhu, Zhi-Lan Zhou, Xue-Bing Jia, Yi-Da Xu, Qin Yang, Chun Cui, Yan-Qin Shen
Parkinson's disease (PD) patients display alterations in gut microbiota composition. However, mechanism between gut microbial dysbiosis and pathogenesis of PD remains unexplored, and no recognized therapies are available to halt or slow progression of PD. Here we identified that gut microbiota from PD mice induced motor impairment and striatal neurotransmitter decrease on normal mice. Sequencing of 16S rRNA revealed that phylum Firmicutes and order Clostridiales decreased, while phylum Proteobacteria, order Turicibacterales and Enterobacteriales increased in fecal samples of PD mice, along with increased fecal short-chain fatty acids (SCFAs)...
February 19, 2018: Brain, Behavior, and Immunity
Sagrario Pérez-de la Cruz
OBJECTIVES: Various exercise strategies have been suggested to address movement deficits in order to improve motor function and quality of life for individuals in the early or moderate stages of Parkinson disease. The purpose is to evaluate the effects of an aquatic Ai Chi intervention on balance, gait speed and quality of life of patients. DESIGN AND INTERVENTION: Twenty-nine people with Parkinson disease participated in this pilot study. People were randomized into (1) aquatic Ai Chi program (experimental group) and (2) a dry land conventional Western physical therapy intervention (control group)...
February 2018: Complementary Therapies in Medicine
Josianne Rodrigues-Krause, Mauricio Krause, Alvaro Reischak-Oliveira
Context • Dancing has been used as a form of exercise to improve functional and metabolic outcomes during aging. The field lacks randomized, clinical trials (RCTs) evaluating metabolic outcomes related to dance interventions, but dancing may be a form of exercise that could induce positive effects on the metabolic health of older adults. However, primary studies seem very heterogonous regarding the trial designs, characteristics of the interventions, the methods for outcomes assessments, statistical powers, and methodological quality...
February 10, 2018: Alternative Therapies in Health and Medicine
Lindsey E Greviskes, Leslie Podlog, Maria Newton, Leland E Dibble, Ryan D Burns, Wanda Pillow, Morgan S Hall, Christopher Hammer
BACKGROUND AND PURPOSE: With Parkinson's disease (PD) prevalence rates steadily increasing and long-term adherence to regular physical activity and exercise often difficult to achieve, it is imperative to investigate factors promoting adherence to secondary prevention programs (SPP) that help limit the progression of motor and nonmotor signs and symptoms of the disease. Caring interactions between patients and their rehabilitation team may be particularly germane to individuals with PD, given the physical and psychosocial issues that often accompany this disease (eg, loss of physical function, depression, apathy, and cognitive impairments)...
February 1, 2018: Journal of Geriatric Physical Therapy
Domenico Intiso, Michelangelo Bartolo, Andrea Santamato, Filomena Di Rienzo
Progressive Supranuclear Palsy (PSP) is a progressive neurodegenerative disorder due to the deposition of abnormal proteins in neurons of the basal ganglia that limit motor ability producing disability and reduced quality of life. So far, no pharmacologic therapy has been developed and the treatment remains symptomatic. The aim of the present study was to investigate systematically literature, and to determine the types and effects of rehabilitative interventions. A search of all studies was conducted in MEDLINE/PubMed, the Cochrane Central Register of Controlled Trials, CINAHL and EMBASE...
January 20, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
Keyte Guedes Silva, Tatiana Beline De Freitas, Flávia Doná, Fernando Freitas Ganança, Henrique Ballalai Ferraz, Camila Torriani-Pasin, José Eduardo Pompeu
Background: There is an association among postural instability, gait dysfunction, and cognitive impairment in subjects with Parkinson's disease (PD). Difficulty in dividing attention, response inhibition, and visuospatial attention deficiencies may contribute to the impairment of motor performance during daily activities. There are strong evidences that physical therapy can prevent physical and cognitive decline in individuals with PD. Recently, the European Physiotherapy Guideline (EPG) was developed based on randomized clinical trials about the effectiveness of the physical therapy to improve the functional deficiencies of individuals with PD...
2017: Pilot and Feasibility Studies
Charlotte A Chatto, Paul T York, Catherine P Slade, Scott M Hasson
BACKGROUND AND PURPOSE: This case addresses feasibility of a home-based telehealth system to enhance home exercise program (HEP) adherence for a patient with Parkinson disease (PD). We describe START-System for Technology-Augmented Rehabilitation and Training-and discuss outcomes after integrating START into the HEP component of an established therapy protocol, Lee Silverman Voice Technique BIG (LSVT BIG). CASE DESCRIPTION: The participant was a 67-year-old woman with PD at Hoehn and Yahr Stage II...
January 2018: Journal of Neurologic Physical Therapy: JNPT
Eleanor Yusupov, Davina Chen, Bhuma Krishnamachari
Objectives: Our goal was to assess the association between potentially inappropriate medication use and risk of falls in the Parkinson's disease population. Methods: This was a retrospective cohort study conducted at an outpatient Parkinson's Disease Treatment Center. Individuals 65 years of age or older, diagnosed with Parkinson's disease who attended at least three visits in 2015 for physical, occupational therapy, or physician's visits were included in the study...
2017: SAGE Open Medicine
Amy W Amara, Adeel A Memon
Patients with Parkinson's disease experience disabling non-motor symptoms, including autonomic dysfunction, cognitive decline, and sleep disorders. Pharmacologic treatments for these symptoms are often ineffective or have intolerable side effects. Therefore, non-pharmacologic interventions are an attractive alternative. Exercise in particular has the potential to alleviate the progressive impairment related to these non-motor symptoms. In this commentary, we explore available research that addresses the impact of exercise and physical activity on autonomic dysfunction, cognitive impairment, and sleep disorders in Parkinson's disease and suggest areas in need of further study...
January 2018: Clinical Therapeutics
Ires Ghielen, Erwin E H van Wegen, Sonja Rutten, Cees J T de Goede, Marieke Houniet-de Gier, Emma H Collette, Ingrid A L Burgers-Bots, Jos W R Twisk, Gert Kwakkel, Kees Vermunt, Bep van Vliet, Henk W Berendse, Odile A van den Heuvel
BACKGROUND: In Parkinson's disease (PD) patients, fluctuations in symptoms commonly occur after many years of dopamine replacement therapy. The so-called wearing-off phenomenon exists of both motor and non-motor symptoms, such as rigidity and anxiety. Current treatment options are limited and an integrated approach is needed to address the complex interactions between motor and non-motor symptoms. Since wearing-off is eventually inevitable, treatment needs to focus on coping, acceptance and self-efficacy...
December 2017: Journal of Psychosomatic Research
Ettore Beghi, Elisa Gervasoni, Elisabetta Pupillo, Elisa Bianchi, Angelo Montesano, Irene Aprile, Michela Agostini, Marco Rovaris, Davide Cattaneo
OBJECTIVE: To compare the risk of falls and fall predictors in patients with Parkinson's disease (PD), multiple sclerosis (MS) and stroke using the same study design. DESIGN: Multicenter prospective cohort study. SETTING: Three [masked] institutions for physical therapy and rehabilitation. PARTICIPANTS: Patients with PD, MS and stroke seen for rehabilitation. MAIN OUTCOME MEASURES: Functional scales were applied to investigate balance, disability, daily performance, self-confidence with balance, and social integration...
November 1, 2017: Archives of Physical Medicine and Rehabilitation
Margaret K Mak, Irene S Wong-Yu, Xia Shen, Chloe L Chung
Parkinson disease (PD) is a progressive, neurodegenerative movement disorder with symptoms reflecting various impairments and functional limitations, such as postural instability, gait disturbance, immobility and falls. In addition to pharmacological and surgical management of PD, exercise and physical therapy interventions are also being actively researched. This Review provides an overview of the effects of PD on physical activity - including muscle weakness, reduced aerobic capacity, gait impairment, balance disorders and falls...
November 2017: Nature Reviews. Neurology
Chieh-Sen Chuang, Jui-Chih Chang, Fu-Chou Cheng, Ko-Hung Liu, Hong-Lin Su, Chin-San Liu
PURPOSE: Parkinson's disease (PD) is a progressive degenerative central nervous system disorder that particularly impairs motor function. As PD advances, gait disorders become more pronounced and are often difficult to treat with current pharmacological therapies. Physical activity improves both mobility in and the daily living activities of patients with PD. Mitochondrial alterations and oxidative stress contribute to PD progression. Therefore, the association between mitochondria and exercise in PD and the implicated regulation of mitochondrial proteins was explored in this study...
December 15, 2017: Life Sciences
Marcela Dos Santos Delabary, Isabel Giovannini Komeroski, Elren Passos Monteiro, Rochelle Rocha Costa, Aline Nogueira Haas
BACKGROUND: Patients with Parkinson's Disease (PD) undergo motor injuries, which decrease their quality of life (QL). Dance, added to drug therapy, can help treating these patients AIMS: To conduct a systematic review with meta-analysis with the aim to analyze the effects of dance classes in comparison to other interventions or to the absence of intervention, in randomized clinical trials (RCTs), on functional mobility, motor symptoms and QL of PD patients METHODS: The search was conducted in MEDLINE, LILACS, SciELO, Cochrane and PsycINFO (last searched in August 2017)...
October 4, 2017: Aging Clinical and Experimental Research
John G Skedros, James S Smith, Tanner D Langston, Micheal G Adondakis
We report the case of a 70-year-old male with Parkinson's disease (PD) and recurrent traumatic left shoulder dislocations. This case is rare because (1) he had a massive irreparable rotator cuff tear and end-stage arthritis (i.e., rotator cuff-tear arthropathy) of the same shoulder and (2) his shoulder was ultimately reconstructed with a reverse total shoulder arthroplasty (RTSA). His first dislocation occurred after a fall. Recurrent shoulder dislocations occurred despite successful closed reduction and physical therapy...
2017: Case Reports in Orthopedics
Priscila A Rocha, Susan C Slade, Jodie McClelland, Meg E Morris
OBJECTIVES: To understand the benefits and limitations of therapeutic dancing classes for people with Parkinson's disease (PD) and how best to design and implement classes. DESIGN: A stakeholder forum explored the opinions of 18 allied health clinicians, dance instructors, people with PD and caregivers. Data were thematically analysed and interpreted within a grounded theory framework. RESULTS: Four main themes were identified: (1) the need to consider the stage of disease progression when designing classes; (2) recognition that dance is more than just therapy; (3) the benefits of carefully selecting music to move by; (4) ways to design classes that are both feasible and engaging...
October 2017: Complementary Therapies in Medicine
Ewelina Pałasz, Agnieszka Bąk, Anna Gąsiorowska, Grażyna Niewiadomska
Glial cells and neurotrophins play an important role in maintaining homeostasis of the CNS. Disturbances of their function can lead to a number of nervous system diseases, including Parkinson's disease (PD). Current clinical studies provide evidence that moderate physical activity adapted to the health status of PD patients can support pharmacological treatment, slow down the onset of motor impairments, and extend the patients period of independence. Physical activity, by stimulating the production and release of endogenous trophic factors, prevents the neurodegeneration of dopaminergic neurons via inhibition of inflammatory processes and the reduction of oxidative stress...
January 4, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
Michelle E Fullard, Dylan P Thibault, Andrew Hill, Joellyn Fox, Danish E Bhatti, Michelle A Burack, Nabila Dahodwala, Elizabeth Haberfeld, Drew S Kern, Olga S Klepitskava, Enrique Urrea-Mendoza, Phillip Myers, Jay Nutt, Miriam R Rafferty, Jason M Schwalb, Lisa M Shulman, Allison W Willis
OBJECTIVE: To examine rehabilitation therapy utilization for Parkinson disease (PD). METHODS: We identified 174,643 Medicare beneficiaries with a diagnosis of PD in 2007 and followed them through 2009. The main outcome measures were annual receipt of physical therapy (PT), occupational therapy (OT), or speech therapy (ST). RESULTS: Outpatient rehabilitation fee-for-service use was low. In 2007, only 14.2% of individuals with PD had claims for PT or OT, and 14...
September 12, 2017: Neurology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"