keyword
https://read.qxmd.com/read/38546126/clinical-and-radiographic-healing-of-nonoperative-and-operative-treatment-of-jones-fractures
#21
JOURNAL ARTICLE
Matthew T Kingery, Manasa L Kadiyala, Raymond Walls, Sanjit R Konda, Abhishek Ganta, Philipp Leucht, Steven Rivero, Kenneth A Egol
BACKGROUND: Significant heterogeneity in the classification and treatment of zone 3 proximal fifth metatarsal base fractures ("true Jones fractures") exists. This study compared time to clinical and radiographic healing between patients treated operatively and nonoperatively. We hypothesized that patients treated nonoperatively may demonstrate a greater time to clinical healing. METHODS: This was a retrospective cohort study of patients presenting to a large, urban, academic medical center with "Jones" fractures between December 2012 and April 2022...
March 28, 2024: Foot & Ankle International
https://read.qxmd.com/read/38546092/enhancing-women-s-quality-of-life-exploring-the-impact-of-mastectomy-with-and-without-breast-reconstruction-among-breast-cancer-survivors-in-iraq
#22
JOURNAL ARTICLE
Bassam Abdul Rasool Hassan, Ali Haider Mohammed, Abeer Abdulhameed Ahmed, Alya A Al Zobair, Abdulrasool M Wayyes, Haidar Kadhim Al-Jawadi, Ahmed Zuhair Abdulhameed Alsammarraie, Musaab Kadhim Alabboodi, Jin Xin Jiang
BACKGROUND AND AIMS: Mastectomy, a common intervention for breast cancer, has substantial implications for a woman's quality of life (QoL). However, the literature on QoL outcomes following mastectomy-with or without breast reconstruction (BR) is scant. This study aims to assess and compare the QoL among Iraqi women post-mastectomy, examining the impacts of undergoing BR. METHODS: We conducted a comprehensive cross-sectional study across multiple centers in Iraq from April to September 2021...
March 1, 2024: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/38546068/high-p16ink4a-expression-keratinizing-features-and-surgical-margin-free-status-are-associated-with-improved-survival-in-patients-with-oral-squamous-cell-carcinomas
#23
JOURNAL ARTICLE
Sumadi Lukman Anwar, Ery Kus Dwianingsih, Setyani Puji Lestari, William Sugandhi, Roby Cahyono, Gizza Dandy Pradana
BACKGROUND: Oral squamous cell carcinoma (OSCC) continues to prevail as a highly prevalent cancer in Southeast Asia and causes a significant health burden. Stratification of patients with high risks of recurrence and mortality is important in the planning of treatment and surveillance. METHODS: Formalin-fixed paraffin-embedded (FFPE) tissues of OSCC were immuno-stained and analyzed for p16 expression. Risk factors and clinical parameters of OSCC patients were collected and compared to identify factors associated with recurrences and overall survival...
March 1, 2024: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/38545860/common-bean-under-different-water-availability-reveals-classifiable-stimuli-specific-signatures-in-plant-electrome
#24
JOURNAL ARTICLE
Gabriel R A de Toledo, Gabriela N Reissig, Luiz G S Senko, Danillo R Pereira, Arlan F da Silva, Gustavo M Souza
Plant electrophysiology has unveiled the involvement of electrical signals in the physiology and behavior of plants. Spontaneously generated bioelectric activity can be altered in response to changes in environmental conditions, suggesting that a plant's electrome may possess a distinct signature associated with various stimuli. Analyzing electrical signals, particularly the electrome, in conjunction with Machine Learning (ML) techniques has emerged as a promising approach to classify characteristic electrical signals corresponding to each stimulus...
December 31, 2024: Plant Signaling & Behavior
https://read.qxmd.com/read/38545827/nivolumab-as-a-promising-treatment-option-for-metastatic-salivary-duct-carcinoma
#25
JOURNAL ARTICLE
Luis Bugia, Frederic Jungbauer, Lena Zaubitzer, Christian Hörner, Kirsten Merx, Abo-Madyan Yasser, Thomas Germann, Anne Lammert, Claudia Scherl, Nicole Rotter, Annette Affolter
Salivary duct carcinomas (SDC) of the parotid gland are rarely occurring highly malignant tumors. A 65-year-old man presented with a preauricular mass. After surgical treatment and histologic examination, the findings were interpreted as a squamous cell carcinoma (SCC) metastasis of the parotid gland deriving from a cancer of unknown primary DD primary SCC of the parotid gland. Adjuvant platinum-based radiochemotherapy was administered in domo. However, re-staging revealed multiple size-progressive pulmonary round lesions...
March 28, 2024: Journal of Immunotherapy
https://read.qxmd.com/read/38545502/implanted-intrathecal-drug-delivery-systems-may-be-associated-with-improved-survival-in-patients-with-cancer
#26
JOURNAL ARTICLE
Alison Mitchell, Lesley Somerville, Nicola Williams, Jonathan McGhie, Alex McConnachie, Gordon McGinn, Jiyoung Lee
BACKGROUND: Intrathecal Drug Delivery Systems (IDDS) are underused in the management of cancer-related pain despite evidence of both efficacy and survival benefit. There is currently limited evidence to indicate which patients might benefit most from IDDS. AIM: The aim of the study was to describe the baseline characteristics and survival outcomes of patients who accepted IDDS, patients who declined IDDS and patients who wished to go ahead with IDDS but whose condition deteriorated before they could do so...
April 2024: British Journal of Pain
https://read.qxmd.com/read/38545425/comparison-of-long-term-outcome-between-clinically-high-risk-lobular-versus-ductal-breast-cancer-a-propensity-score-matched-study
#27
JOURNAL ARTICLE
Francesca Magnoni, Giovanni Corso, Patrick Maisonneuve, Beatrice Bianchi, Giuseppe Accardo, Claudia Sangalli, Giulia Massari, Anna Rotili, Luca Nicosia, Filippo Pesapane, Emilia Montagna, Giovanni Mazzarol, Viviana Galimberti, Paolo Veronesi, Giuseppe Curigliano
BACKGROUND: Abemaciclib is currently approved for the adjuvant treatment of high-risk, lymph node (LN)-positive, hormone receptor (HR)-positive breast cancer (BC). In a real-world setting the clinicopathologic features of patients potentially eligible for adjuvant abemaciclib remain to be defined. There are conflicting data regarding the biological behavior and long-term outcomes across invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC). In our study we retrospectively assessed the real-world data and long-term outcome of selected high-risk features ILC compared to IDC, according to the MonarchE trial inclusion criteria...
May 2024: EClinicalMedicine
https://read.qxmd.com/read/38545332/oral-health-status-and-behaviour-among-kanikkaran-tribes-of-mundandhurai-hills-in-tirunelveli-district-tamil-nadu
#28
JOURNAL ARTICLE
Rahmath Meeral P, Arthi Balasubramaniam, Meignana Arumugham Indiran, Karthik M
BACKGROUND: Kanikkaran are semi-nomadic tribes inhabiting Mundandhurai hills in Tamil Nadu. Their traditional method of maintaining oral health, seclusion, ignorance, and limited access to dental resources has led to their poor oral health situation. Thus, the present study is designed to assess the oral health status of the Kanikkaran tribals residing in Mundandhurai Hill of Tirunelveli district. METHODS: A cross-sectional epidemiological study was conducted among 907 Kanikkaran tribes in Mundandhurai hills...
2024: Journal of Oral Biology and Craniofacial Research
https://read.qxmd.com/read/38545312/the-evaluation-of-the-effectiveness-of-a-health-promotion-training-on-breast-cancer-survivors
#29
JOURNAL ARTICLE
Bahar Kefeli Çol, Gülnihal Tufan, Dilek Kiliç
BACKGROUND: Increased early diagnosis and improved treatment options have decreased the mortality rate of breast cancer and increased the survival rate. Healthy lifestyle behaviors are very important in breast cancer survivors as they reduce mortality and morbidity rates, cancer recurrence frequency, and side effects of treatment and improve health. This study was conducted to evaluate the effectiveness of a health promotion training intervention in breast cancer survival. MATERIALS AND METHODS: The study is a quasi-experimental, pre-test-post-test and single-group study...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38545281/do-people-with-me-cfs-and-joint-hypermobility-represent-a-disease-subgroup-an-analysis-using-registry-data
#30
JOURNAL ARTICLE
Kathleen Mudie, Allison Ramiller, Sadie Whittaker, Leslie E Phillips
BACKGROUND: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic, multifaceted disease that affects millions globally. Despite its significant impact, the disease's etiology remains poorly understood, and symptom heterogeneity poses challenges for diagnosis and treatment. Joint hypermobility, commonly seen in hypermobile Ehlers-Danlos Syndrome (hEDS), has been observed in ME/CFS patients but its prevalence and clinical significance within this population are not well-characterized...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38545061/whole-tumor-histogram-analysis-of-synthetic-magnetic-resonance-imaging-predicts-isocitrate-dehydrogenase-mutation-status-in-gliomas
#31
JOURNAL ARTICLE
Xin Ge, Tiejun Gan, Zhihua Yang, Guangyao Liu, Wanjun Hu, Wenfu Ma, Yuping Bai, Yuhui Xiong, Min Li, Jianguo Zhao, Liang Zhou, Jiachen Li, Darui Li, Xiaodong Wang, Jing Zhang
BACKGROUND: An accurate assessment of isocitrate dehydrogenase (IDH) status in patients with glioma is crucial for treatment planning and is a key factor in predicting patient outcomes. In this study, we investigated the potential value of whole-tumor histogram metrics derived from synthetic magnetic resonance imaging (MRI) in distinguishing IDH mutation status between astrocytoma and glioblastoma. METHODS: In this prospective study, 80 glioma patients were enrolled from September 2019 to June 2022...
March 15, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38545032/risk-factors-of-electrical-status-epilepticus-during-sleep-in-children-with-benign-childhood-epilepsy-with-centro-temporal-spikes
#32
JOURNAL ARTICLE
Xiufeng Wang, Yanling Zhang, Ruixue Sun, Na Kong
OBJECTIVE: To explore risk factors of electrical status epilepticus during sleep in children with benign childhood epilepsy with centro-temporal spikes (BECT). METHODS: This is a clinical comparative study. The subjects of study were 67 children with BECT from the Outpatient Department of Pediatric Neurology in Xingtai People's Hospital from January 2019 to January 2022. According to the occurrence of ESES, the enrolled children were divided into control group which included BECT children without ESES and the observation group which included BECT children with ESES...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38544955/psychological-factors-may-affect-the-quality-of-life-in-irritable-bowel-syndrome-patients-more-than-the-gut-itself-a-multicenter-cross-sectional-study
#33
JOURNAL ARTICLE
Xiaotian Xie, Jing He, Shu Xu, Zhiyue Xu, Yanqin Long, Zhijun Duan, Jie Yang, Zhifeng Zhang, Jun Wu, Lianying Cai, Liexin Liang, Ning Dai, Jun Zhang, Tao Bai, Xiaohua Hou
BACKGROUND AND AIM: Both intestinal symptoms and comorbidities exist in irritable bowel syndrome (IBS) patients and influence their quality of life (QOL). More research is needed to determine how these variables impact the QOL of IBS patients. This study aimed to determine which specific factors had a higher influence on QOL and to further compare the effects of intestinal symptoms and comorbidities on QOL. METHODS: IBS patients were recruited from six tertiary hospitals in different regions of China...
March 2024: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38544885/therapeutic-responses-to-efgartigimod-for-generalized-myasthenia-gravis-in-japan
#34
JOURNAL ARTICLE
Shigeaki Suzuki, Akiyuki Uzawa, Yuriko Nagane, Masayuki Masuda, Shingo Konno, Tomoya Kubota, Makoto Samukawa, Kei Ishizuchi, Daiki Tokuyasu, Hideo Handa, Manato Yasuda, Naoki Kawaguchi, Takashi Kimura, Yasushi Suzuki, Takamichi Sugimoto, Naoya Minami, Masanori P Takahashi, Hiroyuki Murai, Kimiaki Utsugisawa
BACKGROUND AND OBJECTIVES: Efgartigimod, which has been well tolerated and efficacious in individuals with generalized myasthenia gravis (MG), is available in Japan not only for the treatment of anti-acetylcholine receptor-positive (AChR+) but also anti-muscle-specific receptor tyrosine kinase (MuSK+) and seronegative generalized MG. We report details of the use of efgartigimod for generalized MG in clinical practice in Japan. METHODS: We included patients with generalized MG in the 2021 survey of Japan Myasthenia Gravis Registry (JAMG-R) study group who received an initial cycle of efgartigimod between May and September 2022...
June 2024: Neurology. Clinical Practice
https://read.qxmd.com/read/38544877/cementoplasty-to-cryoablation-review-and-current-status
#35
REVIEW
Jin Rong Tan, Yet Yen Yan, Adnan Sheikh, Hugue Ouellette, Paul Mallinson, Peter L Munk
Recent advances in percutaneous image-guided techniques have empowered interventional radiologists with diverse treatment options for the management of musculoskeletal lesions. Of note, there is growing utility for cementoplasty procedures, with indications ranging from stabilization of bone metastases to treatment of painful vertebral compression fractures. Likewise, cryoablation has emerged as a viable adjunct in the treatment of both primary and secondary bone and soft tissue neoplasms. These treatment options have been progressively incorporated into the multidisciplinary approach to holistic care of patients, alongside conventional radiotherapy, systemic therapy, surgery, and analgesia...
January 2024: BJR open
https://read.qxmd.com/read/38544852/state-of-perinatal-mental-health-care-in-the-who-region-of-europe-a-scoping-review
#36
JOURNAL ARTICLE
Anna Horakova, Hana Nemcova, Kristyna Hrdlickova, Stefani Kalli, Alina Davletova, Mario Filipe Rodrigues Saraiva Duarte, Darya Molodina, Tiina Riekki, Antonin Sebela
BACKGROUND: Although perinatal mental disorders are the most common health complication among women in the perinatal period, there is a huge gap in the implementation of related research findings in the health care system. We mapped the state of perinatal mental health (PMH) care in the WHO Europe region with aim to identify leading countries, which can serve as models for countries with less developed perinatal mental health care. METHODS: Guidelines, policies, and documents related to screening and treatment services for PMH were searched as grey literature...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38544723/incidence-and-predictors-of-loss-to-follow-up-among-adult-patients-receiving-antiretroviral-therapy-in-central-ethiopia-a-multi-center-retrospective-cohort-study
#37
JOURNAL ARTICLE
Asfaw Anulo, Addisu Girma, Gezahegn Tesfaye, Fekede Asefa, Abera Cheru, Arega Abebe Lonsako
BACKGROUND: Globally, loss to follow-up (LTFU) remains a significant public health concern despite the rapid expansion of antiretroviral medication programs. It is a significant cause of treatment failure and threatens the enhancement of HIV treatment outcomes among patients on antiretroviral therapy (ART). However, there is a paucity of evidence on its incidence and predictors in Ethiopia. Thus, this study aimed to examine the incidence and predictors of LTFU among adult HIV patients receiving ART at hospitals in Central Ethiopia...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38544627/unusual-presentation-of-corynebacterium-endocarditis-in-a-patient-without-conventional-risk-factors-a-case-report
#38
Abbas Mohammadi, Dima Youssef, Ashkan Mohammadi
Infective endocarditis (IE) is a widespread condition marked by the infection of native or prosthetic heart valves, the endocardial surface, or an indwelling cardiac device. While native-valve IE is uncommon, patients with IE represent a diverse spectrum. Some respond well to treatment with few complications, while others face severe complications and an increased risk of mortality. Various factors contribute to this outcome, including delayed diagnosis, underlying health conditions like immunocompromised status or chronic diseases, and intravenous drug use...
February 2024: Curēus
https://read.qxmd.com/read/38544531/treatment-outcome-of-drug-resistant-skeletal-tuberculosis-a-retrospective-analysis
#39
JOURNAL ARTICLE
Himanshu Gupta, Rajesh Arora, Manish Chadha, I K Dhammi, Anil K Jain
BACKGROUND: Management outcomes of drug-resistant (DR) osteoarticular tuberculosis (OATB) is dismal as in pre-ATT era (1905). The studies documenting treatment outcome of DR-OATB are scarce; hence, present retrospective analysis was conducted to evaluate outcome of consecutive cases of DR-OATB. METHODS: 45 consecutive patients of suspected DR-OATB were treated from 2010 onwards. Tissue samples were submitted for AFB smear, cytology/histology, liquid culture, CBNAAT/LPA besides gram's staining and aerobic/anaerobic culture...
April 2024: Indian Journal of Orthopaedics
https://read.qxmd.com/read/38544493/association-of-cardiometabolic-multimorbidity-with-all-cause-and-cardiovascular-disease-mortality-among-chinese-hypertensive-patients
#40
JOURNAL ARTICLE
Luo-Xi Xiao, Zi-Yu Wang, Jiang-Tao Li, Hai-Mei Wang, Yi-Ming Hao, Pan Zhou, Yu-Lin Huang, Qiu-Ju Deng, Yong-Chen Hao, Na Yang, Li-Zhen Han, Zhao Yang, Ping-Ping Jia, Yue Qi, Jing Liu
BACKGROUND: Hypertension usually clusters with multiple comorbidities. However, the association between cardiometabolic multimorbidity (CMM) and mortality in hypertensive patients is unclear. This study aimed to investigate the association between CMM and all-cause and cardiovascular disease (CVD) mortality in Chinese patients with hypertension. METHODS: The data used in this study were from the China National Survey for Determinants of Detection and Treatment Status of Hypertensive Patients with Multiple Risk Factors (CONSIDER), which comprised 5006 participants aged 19-91 years...
February 28, 2024: Journal of Geriatric Cardiology: JGC
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