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Hannaneh Tashackori, Mohsen Sharifi, Najmeh Ahmadian Chashmi, Mehrdad Behmanesh, Naser Safaie
Elicitation of Linum album hairy roots by Piriformospora indica cell wall induced the target genes and specific metabolites in phenylpropanoid pathway and shifted the amino acid metabolism toward the phenolic compound production. Plants have evolved complex mechanisms to defend themselves against various biotic stresses. One of these responses is the production of metabolites that act as defense compounds. Manipulation of plant cell cultures by biotic elicitors is a useful strategy for improving the production of valuable secondary metabolites...
August 14, 2018: Planta
Prashantha Hebbar, Rasheeba Nizam, Motasem Melhem, Fadi Alkayal, Naser Elkum, Sumi Elsa John, Jaakko Tuomilehto, Osama Alsmadi, Thangavel Alphonse Thanaraj
Abnormal blood lipid levels are influenced by genetic and lifestyle/dietary factors. Although many genetic variants associated with blood lipid traits have been identified in Europeans, similar data in Middle Eastern populations are limited. We performed a genome-wide association study with Arab individuals (discovery cohort: 1,353; replication cohort: 1,176) from Kuwait to identify possible associations of genetic variants with high lipid levels. We used Illumina HumanOmniExpress BeadChip and candidate SNP genotyping in the discovery and replication phases, respectively...
August 14, 2018: Journal of Lipid Research
Mostafa Somri, Luis Gaitini, Ibrahim Matter, Naser Hawash, Octavio Falcucci, Gustavo Garcia Fornari, Pedro Charco Mora, Swaid Forat, Sonia Vaida
Background and Aims: The Supreme laryngeal mask airway (SLMA) and the laryngeal tube suction-disposable (LTS-D), both second-generation supraglottic airway devices, have a record of efficiency when used for airway management in mechanically ventilated patients, during general anesthesia. There is no published data comparing these two devices in patients breathing spontaneously during general anesthesia. Material and Methods: Eighty patients with normal airways undergoing elective general anesthesia with spontaneous ventilation were randomized to airway management with a SLMA or LTS-D...
April 2018: Journal of Anaesthesiology, Clinical Pharmacology
Mina Salehi, Ahmad Moieni, Naser Safaie
The microbial fermentation is considered as the potential source for large-scale production of paclitaxel. Since co-cultivation/mixed fermentation strategy has been reported as a yield enhancement strategy for paclitaxel production, investigation of fungal endophyte response to plant culture medium, plant cell extract (CE) and medium filtrate (MF) of plant cell suspension culture in terms of growth and paclitaxel production is interesting. In this study, 35 endophytic fungi were isolated from Taxus baccata and Corylus avellana grown in Iran...
August 13, 2018: Scientific Reports
Nasrollah Ahmadifard, Vahid Rezaei Aminlooi, Amir Tukmechi, Naser Agh
The present study investigated the effect of enriched Artemia with Bacillus subtilis on growth performance, reproductive factors, proximate composition, intestinal microflora, and resistance to Aeromonas hydrophila of ornamental fish, Poecilia latipinna. Using a completely randomized design, the experiment included three groups. The first group was fed with commercial food without any probiotic. The second group was fed with unenriched Artemia, and the last group consumed long-time enriched Artemia with Bacillus subtilis...
August 10, 2018: Probiotics and Antimicrobial Proteins
Mehran Alavi, Naser Karimi
Fighting of current antibiotics against multidrug-resistant (MDR) bacteria has not been completely successful. In this study, the bio-synthesized Ag-TiO2 , TiO2 -Ag, Ag-Cu and Cu-Ag nanocomposites (NCs) were used against MDR bacteria including Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853 (gram negative) and Staphylococcus aureus ATCC 43300 (gram positive). Antiplanktonic, antibiofilm, antiswarming motility and antiquorum sensing activities of these four NCs were measured by assays of agar well diffusion, minimum inhibition/minimum bactericidal concentrations (MIC/MBC), biofilm formation, biofilm morphology and pyocyanin amounts...
August 10, 2018: Artificial Cells, Nanomedicine, and Biotechnology
Ahmed Mustafa, Naser E Bilal, Awad-Elkareem Abass, Elhassan M Elhassan, Ishag Adam
OBJECTIVE: To investigate the association between Helicobacter pylori seropositivity and low birthweight (LBW). METHODS: The present case-control study was conducted at a Sudanese maternity hospital from September fi1rst to December 30, 2015. Patients who delivered single neonates with LBW (>500 g but <2500 g) and the subsequent singleton delivery with birthweight of 2500-4000 g were included. A questionnaire was used to collect medical and obstetric data...
August 9, 2018: International Journal of Gynaecology and Obstetrics
Waheeb Nasr Naser, Huda Ba Saleem
BACKGROUND: Medical professionals together with other first responder teams are the first to attend an emergency or disaster. Knowledge and training in emergency and disaster preparedness are important in responding effectively. This study aims to assess the current knowledge, attitude and training in emergency and disaster preparedness among Yemeni health professionals. METHOD: A descriptive, cross-sectional, non-probability based study was conducted in Yemen using self-reported on-line and paper surveys in 2017...
August 6, 2018: BMC Emergency Medicine
Marwan Jalambo, Norimah Karim, Ihab Naser, Razinah Sharif
Background: Iron deficiency and iron-deficiency anaemia are associated with oxidative stress, but their role is largely unclear. Information is scarce on the effects of iron supplementation on biomarkers of oxidative stress in humans. Aims: This study evaluated the effectiveness of iron supplementation and nutrition education on improving the levels of haemoglobin and ferritin, and decreasing oxidative stress among iron-deficient female adolescents in Gaza, Palestine...
July 29, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
Ahmad Qasem, Saleh A Naser
Background The role of Mycobacteriumavium subspecies paratuberculosis (MAP) in Crohn's disease (CD) is increasingly accepted as evident by detection of the bacteria in the blood and intestinal tissue from patients with CD, and by supporting data from several open-label anti-MAP treatment studies. Tumour necrosis factor alpha (TNFα) monoclonal antibodies (anti-TNFα) have been widely used for CD treatment. Despite the short-term benefit of anti-TNFα in controlling CD symptoms, most patients suffer from detrimental adverse effects, including higher susceptibility to mycobacterial infections...
2018: BMJ Open Gastroenterology
Hiroki Ohashi, Mohammad Al-Naser, Sheraz Ahmed, Katsuyuki Nakamura, Takuto Sato, Andreas Dengel
This paper presents a simple yet effective method for improving the performance of zero-shot learning (ZSL). ZSL classifies instances of unseen classes, from which no training data is available, by utilizing the attributes of the classes. Conventional ZSL methods have equally dealt with all the available attributes, but this sometimes causes misclassification. This is because an attribute that is effective for classifying instances of one class is not always effective for another class. In this case, a metric of classifying the latter class can be undesirably influenced by the irrelevant attribute...
August 1, 2018: Sensors
Naser Bazina, Jibin He
During the deep fat food frying process, the frying media, oil, continuously degenerates when exposed to high temperature, oxygen and moisture. This leads to physical and chemical changes including the formation of hydrolysis products such as free fatty acids (FFAs) which are associated with undesirable darkening in colour, off-flavouring and a lowering of the smoke point. This study was aiming to develop a method capable of identifying and quantifying individual free fatty acids within oil using a small sample size (100 mg of oil)...
August 2018: Journal of Food Science and Technology
Farah Al-Saffar, Clinton Jokerst, Naser Ammash, Susan Wilansky
No abstract text is available yet for this article.
October 2017: CASE: Cardiovascular Imaging Case Reports
Liqing Li, Tomasz Kołodziej, Naser Jafari, Jing Chen, Haining Zhu, Zenon Rajfur, Cai Huang
Phosphatidylinositol 4-phosphate 5-kinase type I γ (PIPKIγ90) regulates cell migration, invasion, and metastasis. However, it is unknown how cellular signals regulate those processes. Here, we show that cyclin-dependent kinase 5 (Cdk5), a protein kinase that regulates cell migration and invasion, phosphorylates PIPKIγ90 at S453, and that Cdk5-mediated PIPKIγ90 phosphorylation is essential for cell invasion. Moreover, Cdk5-mediated phosphorylation down-regulates the activity of PIPKIγ90 and the secretion of fibronectin, an extracellular matrix protein that regulates cell migration and invasion...
July 24, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Mona Zamanian Azodi, Mostafa Rezaei Tavirani, Afsaneh Arefi Oskouie, Vahid Mansouri, Mostafa Hamdieh, Naser Nejati, Mohsen Hamid-Pour, Alireza Ahmadzadeh, Mohammad Rostami-Nejat, Majid Rezaei Tavirani, Seyed Abdolreza Mortazavi Tabatabaei
Introduction: Obsessive-Compulsive Disorder (OCD) as one of the important mental problems is valuable topic for proteomic research studies to better understand the underlying mechanisms of this disorder. Methods: In this paper, gel-based proteomic was used to investigate the proteome profile of 16 female patients with OCD, washing subtype before and after treatment with fluoxetine and comparing them with 20 healthy female controls. Results: One of the abnormally expressed protein spots in this study was introduced and examined for protein-protein interaction network analysis via Cytoscape and its plug-ins...
May 2018: Basic and Clinical Neuroscience
Naser Amini, Nasim Vousooghi, Akram Alizade, Sara Ramezani, Mohammad T Joghataei, Peiman Brouki Milan, Soraya Mehrabi, Shima Ababzadeh, Farshid Sefat, Masoud Mozafari
Cell therapy is an important strategy for the treatment of incurable diseases including those that occur in the central nervous system (CNS). Among different strategies, the method of delivering or transplantation of cells into the brain has shown significant effects on regeneration. In this study, a new protocol has been developed for the transplantation of adipose tissue-derived stem cells into the brain through cerebrospinal fluid (CSF) in rat models. For this purpose, a wide range of ages (7-30 days old) of male neonates of Wistar rats was used...
July 19, 2018: Current Stem Cell Research & Therapy
Abbas Ali Mansour, Ali Hussain Ali Alhamza, Ammar Mohammed Saeed Abdullah Almomin, Ibrahim Abbood Zaboon, Nassar Taha Yaseen Alibrahim, Rudha Naser Hussein, Muayad Baheer Kadhim, Haider Ayad Yassin Alidrisi, Hussein Ali Nwayyir, Adel Gassab Mohammed, Dheyaa Kadhim Al-Waeli, Ibrahim Hani Hussein
Background:  Sellar and parasellar region lesions spectrum includes a wide variety of diseases. This study aimed at providing a comprehensive overview of such lesions in patients from  Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah (Southern Iraq). Methods: Retrospective data analysis from FDEMC for the period January 2012 through June 2017. We included all patients with sellar and parasellar region lesions who received a MRI scan on their pituitary region Results: The total enrolled patients were 232 (84 men and 148 women),with age range 15-75 years...
2018: F1000Research
Aala Darki, Peiman Masoumi, Abbas Soleimani, Abdorreza Naser Moghadasi
Natalizumab is among the most effective drugs for controlling multiple sclerosis (MS). The most important side effect of this drug is progressive multifocal leukoencephalopathy, although some other complications are increasingly reported in literature such as meningitis and encephalitis. Here, a patient with MS who has suffered from myocardial infarction (MI) after the injection of natalizumab is introduced.
July 11, 2018: Multiple Sclerosis and related Disorders
Aurash Naser-Tavakolian, Mittul Gulati, Vinay Duddalwar, Shefali Chopra, Manju Aron, Hooman Djaladat
Liposarcoma is the most common paratesticular scrotal malignancy. Ultrasound is the conventional imaging modality for evaluating scrotal masses. Contrast-enhanced ultrasound (CEUS) can provide complementary information by identifying distinct enhancement patterns. We present CEUS findings of 2 concurrent soft tissue masses in 1 patient: a spermatic cord well-differentiated liposarcoma and a retroperitoneal dedifferentiated liposarcoma. We review the Doppler ultrasound, computed tomography, and histopathologic appearances of low- versus high-grade liposarcomas in addition to the utility of CEUS with quantitative analysis in potentially grading liposarcomas...
July 17, 2018: Ultrasound Quarterly
Roghayyeh Baghban, Safar Farajnia, Younes Ghasemi, Mojtaba Mortazavi, Nosratollah Zarghami, Naser Samadi
BACKGROUND: Although Pichia pastoris is an outstanding host among conventional expression systems for production of recombinant proteins, a new interest have been emerged to this system due to the inherent advantages and new developments in this expression host. The potential for secretory and soluble expression of heterologous glycoproteins in P. pastoris proposed this system as a candidate for the production of complex eukaryotic proteins. METHODS: Several new developments have been occurred in different areas related to P...
July 17, 2018: Current Pharmaceutical Biotechnology
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