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Naser Mobarra, Masoud Soleimani, Majid Ghayour-Mobarhan, Samaneh Safarpour, Gordon A Ferns, Reza Pakzad, Parvin Pasalar
A suitable alternative strategy for liver transplantation is the use of nanofibrous scaffolds together with stem cells. In this study, a random hybrid of poly-l-lactic acid (PLLA) and poly(ε-caprolactone) (PCL) was used as a three-dimensional (3D) culture for differentiation of hepatocyte-like cells and compared with routine culture (two-dimensional [2D]). The expression of the endodermal marker, forkhead box A2 (FOXA2), was assessed on Day 3 and the hepatic markers; albumin (ALB), α-1 antitrypsin (AAT), and cytokeratin-18 (CK-18) were evaluated on Day 18 using quantitative polymerase chain reaction qPCR...
December 4, 2018: Journal of Cellular Physiology
Farzaneh Afkhaminia, Hasan Siamian, Naser Behnampour, Adib Moghimi, Shiva Karimpour
Background: One of the performance measures of any educational system is the degree to which students learn their education. Academic achievement includes the acquisition of a set of skills and abilities that are acquired during the course and in decision making and the various issues of leadership of individuals. A variety of factors affect the academic success of students. The present study aims to investigate the successful student's point of view from students of Mazandaran University of Medical Sciences in 2016-2017...
October 2018: Acta Informatica Medica: AIM
Azra Durak-Nalbantic, Alen Dzubur, Naser Nabil, Aida Hamzic-Mehmedbasic, Faris Zvizdic, Enisa Hodzic, Nerma Resic
Introduction: Heart failure (HF) has very high rate of repeat hospitalizations due to HF decompensation (HHFD), sometimes very shortly after discharge for acute HF. Aim: The aim of this paper is to investigate rate of HHFD and to identify their possible predictors. Patients and Methods: Total amount of 222 patients hospitalized at Clinic for heart and vessel disease and rheumatism in acute HF were followed for next 18 months for occurrence of HHFD...
October 2018: Medical Archives
Alexander C Egbe, William R Miranda, Naser M Ammash, Nandan S Anavekar, Venkata R Missula, Srikanth Kothapalli, Arooj R Khan, Sameh M Said, Heidi M Connolly
BACKGROUND: Aortic dilation and aortic valve disease are known long-term complication of tetralogy of Fallot (TOF), but the risk of aortic dissection and the indications for prophylactic aortic surgery are unknown in this population. The purpose of this study was to: (1) determine the prevalence of significant aortic valve disease and/or significant aortic aneurysm (AVD-AA); (2) determine the incidence of progressive aortic dilation and aortic dissection in patients with TOF. METHODS: Retrospective review of adults with repaired TOF, and no prior aortic valve/aorta surgery, who had ≥2 measurements of the thoracic aorta >12 months apart, 1990-2017...
December 4, 2018: Heart: Official Journal of the British Cardiac Society
Abdelgawad A Fahmi, Mariam Abdur-Rahman, Asmaa F Aboul-Naser, Manal A Hamed, Howida I Abd-Alla, Mohamed I Nasr
CONTEXT: Stomach ulcers are the common gastrointestinal disorders worldwide. OBJECTIVE: This study aimed to investigate the therapeutic impact of Pulicaria crispa aerial part ethanol extract against gastric ulcer in rats. MATERIALS AND METHODS: Ulcer was induced by one oral dose of ethanol (0.5 ml/100g body weight) on 24 hours empty stomach, then the plant extract (500 mg/kg b.wt.) was orally administered daily for one week. Ranitidine (100mg/kg b...
December 4, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
Michael Lajin, Marc F Catalano, Naser Khan, Simon Lavotshkin, Samer El-Dika
No abstract text is available yet for this article.
December 2018: VideoGIE: an official video journal of the American Society for Gastrointestinal Endoscopy
Naser Alotaibi, Fahad Manee, Lisa Murphy, Mehdi Rassafiani
OBJECTIVES: In Kuwait, knowledge and attitudes of the health care teams toward occupational therapy practice (OTP) have not been investigated. This current study, sought to explore the knowledge about, and attitudes of interdisciplinary team members toward OTP. SUBJECTS AND METHODS: This cross-sectional study involved developing and validating a tool to serve the purpose of the study. We used a modified Delphi method to develop a tool that assessed OT knowledge (OT areas of practice, domains and philosophy) as well as attitudes toward OTP...
December 2, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Raedeh Saraei, Faroogh Marofi, Adel Naimi, Mehdi Talebi, Mahnaz Ghaebi, Naser Javan, Omid Salimi, Ali Hassanzadeh
Flavonoids are a varied family of phytonutrients (plant chemicals) usually are detected in fruits and vegetables. In this big family, there exist more than 10,000 members that is separated into six chief subtypes: isoflavonols, flavonoenes, flavones, flavonols, anthocyanins, and chalcones. The natural compounds, such as fruits, have visible positive effects in regulating of survival involved signaling pathways that performance as the regulator of cell survival, growth, and proliferation. Researchers have established that commonly consumption up flavonoids decreases incidence and development risk of certain cancers, especially leukemia...
November 30, 2018: Journal of Cellular Physiology
Shiva Najafi Kakavand, Naser Karimi, Hamid-Reza Ghasempour
The presence of heavy metals in the soils is undoubtedly one of the prime abiotic stresses in the world. There are a considerable amount of plant yield losses because of heavy metal stress. The goal of this study was to assess the morphological, physiological and biochemical changes in Alyssum inflatum Nyár. populations upon exposure to different levels of nickel (Ni) (0, 100, 200, 400) μM, salicylic acid (SA) (0, 50, 200) μM and jasmonic acid (JA) (0, 5, 10) μM. Results showed that there were no considerable interpopulation differences, including the shoot Ni concentrations...
November 14, 2018: Plant Physiology and Biochemistry: PPB
Amir Tavakoli Kareshk, Razieh Tavakoli Oliaee, Hossein Mahmoudvand, Amir Keyhani, Mohammad Ali Mohammadi, Mehdi Bamorovat, Mohammad Ali Hajhosseini, Naser Zia-Ali
Background: We isolated Toxoplasma gondii from camels by bioassay method in mice model and detect parasitic DNA in brain mice by molecular methods. Methods: One hundred tissue samples including heart (n=50), and diaphragm (n=50) were collected from camels (n=50) slaughtered in abattoirs from Feb to Oct 2015 in three provinces located in eastern Iran. In first, blood sample from 50 camels was assayed for anti- Toxoplasma antibodies by modified agglutination test (MAT) test...
July 2018: Iranian Journal of Parasitology
Sareh Shahmohammadi, Rozita Doosti, Abootorab Shahmohammadi, Seyed Ehsan Mohammadianinejad, Mohammad Ali Sahraian, Amir Reza Azimi, Mohammad Hossein Harirchian, Nasrin Asgari, Abdorreza Naser Moghadasi
INTRODUCTION: Neuromyelitis Optica (NMO) is an autoimmune inflammatory demyelinating disease of the central nervous system (CNS) which predominantly involves optic nerves and spinal cord. Since the introduction of Neuromyelitis Optica Spectrum Disorders (NMOSD) as a separate entity, there have been many reports on its association with other disorders including systemic and organ-specific autoimmune diseases. Here, we reviewed other immune-mediated diseases associated with NMOSD and tried to categorize them...
November 16, 2018: Multiple Sclerosis and related Disorders
Seble Girma, James Cheaveau, Abu Naser Mohon, Dewdunee Marasinghe, Ruth Legese, Nirujah Balasingam, Adugna Abera, Sindew M Feleke, Lemu Golassa, Dylan R Pillai
Background: As the global public health objectives for malaria evolve from malaria control towards malaria elimination, there is increasing interest in the significance of asymptomatic infections and the optimal diagnostic test to identify them. Method: We conducted a cross-sectional study of asymptomatic individuals (n=562) to determine epidemiological characteristics associated with asymptomatic malaria. Participants were tested by RDTs (CareStart TM, SD Bioline, and Alere uRDT), LAMP, and quantitative reverse transcription (RT)-PCR to determine malaria positivity...
November 26, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Abdallah Y Naser, Ian Chi Kei Wong, Cate Whittlesea, Maedeh Y Beykloo, Kenneth K C Man, Wallis C Y Lau, Dana Abdel-Halim Hyassat, Li Wei
OBJECTIVE: To assess whether the use of multiple antidiabetic medications is associated with an increased risk of hypoglycaemia in patients with type 2 diabetes mellitus. DESIGN: A case-crossover study. SETTING: Cases were enrolled from the National Center for Diabetes, Endocrinology and Genetics in Amman, Jordan. PARTICIPANTS: Patients were those with diabetes mellitus and reported incident of a hypoglycaemic event in their medical records during the period January 2007 to July 2017...
November 21, 2018: BMJ Open
Naser Nawayseh, Sadeque Hamdan
Several studies have investigated the transmission of vibration from the vibrating plate of a whole-body vibration training machine (WBVTM) to different locations on the human body. No known work has investigated the interface force between the vibrating plate of the machine and the human body. This paper investigates the effect of bending the knees and the vibration frequency on the interface force (presented as apparent mass (AM)) between the vibrating plate and the body. Twelve male subjects stood with four different knee angles (180, 165, 150 and 135°) and were exposed to sinusoidal vertical vibration at eight frequencies in the range of 17-42 Hz...
November 13, 2018: Journal of Biomechanics
James Cheaveau, Hong Nguyen, Barbara Chow, Dewdunee Marasinghe, Abu Naser Mohon, Hong Yuan, Gisele Viana, Donelly van Schalkwyk, Deirdre Church, Wilson Chan, Dylan R Pillai
The mainstay of malaria diagnosis relies on rapid diagnostic tests (RDTs) and microscopy, both of which lack analytical sensitivity. This leads to repeat testing to rule out malaria. A prospective diagnostic trial of the Meridian illumigene Malaria assay (loop-mediated isothermal amplification [LAMP]) was conducted comparing it with reference microscopy and RDTs (BinaxNOW Malaria) in returning travelers between June 2017 and January 2018. Returning travelers with signs and symptoms of malaria were enrolled in the study...
November 2018: Open Forum Infectious Diseases
Naser Gharebaghi, Miramir Aghdashi, Seyed Arman Seyed Mokhtari
Kawasaki disease (KD) is characterized with an acute systemic vasculitis of the medium- and small-sized vessels. This disease mainly involves children within the age of 6 months to 5 years and it is often self-limited and patients seem to recover well; however, it may lead to devastating and fatal cardiovascular complications such as coronary artery aneurysm. Thus, early diagnosis and appropriate management of this disease have a significant effect on improving the prognosis and preventing its serious complications...
2018: International Medical Case Reports Journal
Majid Ghareghani, Russel J Reiter, Kazem Zibara, Naser Farhadi
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). While the etiology of MS is still largely unknown, scientists believe that the interaction of several endogenous and exogenous factors may be involved in this disease. Epidemiologists have seen an increased prevalence of MS in countries at high latitudes, where the sunlight is limited and where the populations have vitamin D deficiency and high melatonin levels. Although the functions and synthesis of vitamin D and melatonin are contrary to each other, both are involved in the immune system...
2018: Frontiers in Immunology
Mike Kareh, Rana El Nahas, Lamis Al-Aaraj, Sara Al-Ghadban, Nataly Naser Al Deen, Najat Saliba, Marwan El-Sabban, Rabih Talhouk
Objective: Sea cucumbers are considered among the most important functional foods. Following bioassay guided fractionation, we assessed the anti-proliferative and anti-inflammatory activities of Holothuria polii ( H. polii ) extracts. Methods: Sea cucumber ethanolic extract and the partially purified aqueous fractions were assessed for their anti-proliferative activities. These latter bioactivities were evaluated in the highly invasive MDA-MB-231 human breast cancer cells in two-dimensional and three-dimensional cultures using trypan blue exclusion assay...
2018: SAGE Open Medicine
Maryam Rahimi, Mina Ghoreshi, Bahman Emami, Mohammad Naser Shafei, Mahmoud Hosseini, Abolfazl Khajavirad
Background: Rosa damascena (R.D) is an aromatic plant with numerous therapeutic effects including cardiovascular effect. The mechanism cardiovascular effect of R.D is unclear and suggested mediated through renin-angiotensin system (RAS). Therefore, in this study, the role of hydroalcoholic extract of R.D on acute hypertension induced by AngII was evaluated. Methods: After anesthesia, femoral artery and vein of rats were cannulated for recording cardiovascular responses and drug injection, respectively...
2018: International Journal of Preventive Medicine
Zhenbo Liu, Naser El-Sheimy, Chunyang Yu, Yongyuan Qin
In the typical Inertial Navigation System (INS)/ Global Navigation Satellite System (GNSS) setup for ground vehicle navigation, measures should be taken to maintain the performance when there are GNSS signal outages. Usually, aiding sensors are utilized to reduce the INS drift. A full motion constraint model is developed allowing the online calibration of INS frame with respect to (w.r.t) the motion frame. To obtain better heading and lateral positioning performance, we propose to use of vanishing point (VP) observations of parallel lane markings from a single forward-looking camera to aid the INS...
May 20, 2018: Micromachines
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