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Ahmad Hersi

Amjad M Ahmed, Ahmad Hersi, Walid Mashhoud, Mohammed R Arafah, Paula C Abreu, Mohammed Abdullah Al Rowaily, Mouaz H Al-Mallah
BACKGROUND: Limited data exist on the epidemiology of cardiovascular risk factors in Saudi Arabia, particularly in relation to the differences between Saudi nationals and expatriates in Saudi Arabia. The aim of this analysis was to describe the current prevalence of cardiovascular risk factors among patients attending general practice clinics across Saudi Arabia. METHODS: In this cross-sectional epidemiological analysis of the Africa Middle East Cardiovascular Epidemiological (ACE) study, the prevalence of cardiovascular risk factors (hypertension, diabetes, dyslipidemia, obesity, smoking, abdominal obesity) was evaluated in adults attending primary care clinics in Saudi Arabia...
October 2017: Journal of the Saudi Heart Association
Gerasimos Filippatos, David Birnie, Michael R Gold, Bart Gerritse, Ahmad Hersi, Sandra Jacobs, Kengo Kusano, Christophe Leclercq, Wilfried Mullens, Bruce L Wilkoff
The AdaptResponse trial is designed to test the hypothesis that preferential adaptive left ventricular-only pacing with the AdaptivCRT(®) algorithm reduces the incidence of the combined endpoint of all-cause mortality and intervention for heart failure (HF) decompensation, compared with conventional cardiac resynchronization therapy (CRT), among patients with a CRT indication, left bundle branch block (LBBB) and normal atrioventricular (AV) conduction. The AdaptResponse study is a prospective, randomized, controlled, single-blinded, multicentre, clinical trial (ClinicalTrials...
July 2017: European Journal of Heart Failure
M Ajlan, L Almazroa, Khalid F AlHabib, Abdelfatah A Elasfar, Hussam Alfaleh, Hanan Albackr, Tarek Kashour, Ahmad Hersi, Gamal A Hussein, Layth Mimish, Ali Almasood, Waleed AlHabeeb, Saleh AlGhamdi, Mubrouk Alsharari, Esmail Chakra, Asif Malik, Raza Soomro, Abdullah Ghabashi, Mushabab Al-Murayeh, Ahmed Abuosa
Effect of atrial fibrillation (AF) on short- and long-term outcomes in heart failure (HF) is controversial. Accordingly, we examined this relationship in a national multicenter project using data from the Hearts Function Assessment Registry Trial in Saudi Arabia that studied the clinical features and outcomes of patients admitted with de novo and acute on chronic HF. Out of 2593 patients with HF, 449 (17.8%) had AF at presentation. Patients with AF were more likely to be males and older (mean age 65.2 ± 15...
January 1, 2017: Angiology
Ahmad Hersi, J Peter Giannoccaro, Andrew Howarth, Derek Exner, Sarah Weeks, Ingo Eitel, R Cameron Herman, Henry Duff, Debbie Ritchie, Maureen Mcrae, Robert Sheldon
BACKGROUND: Hypertrophic cardiomyopathy (HCM), characterized by a thickened, fibrotic myocardium, remains the most common cause of sudden cardiac death in young adults. Based on animal and clinical data, we hypothesized that atorvastatin would induce left ventricular (LV) mass regression. METHODS: Statin Induced Regression of Cardiomyopathy Trial (SIRCAT) was a randomized, placebo-controlled study. The primary endpoint was change in LV mass measured by cardiac magnetic resonance imaging 12 months after treatment with once-daily atorvastatin 80 mg or placebo...
October 2016: Heart Views: the Official Journal of the Gulf Heart Association
Waleed Alhabeeb, Abdelfatah Elasfar, Hanan AlBackr, Fayez AlShaer, Ali Almasood, Hussam Alfaleh, Tarek Kashour, Ahmad Hersi, Kazi Nur Asfina, Hani Altaradi, Waleed AlShaqhaa, Fakhr Alayoubi, Khalid F AlHabib
BACKGROUND: Several registries have described patients hospitalized with heart failure (HF), but only few looked at outpatients in the ambulatory setting mostly without long-term follow-up. We sought to determine the clinical characteristics, management, and 1-year outcomes of patients with chronic HF in Saudi Arabia. METHODS: Part of a prospective multicenter nationwide registry; HEart function Assessment Registry Trial in Saudi Arabia (HEARTS) and included chronic HF patients referred to four HFCs between September 2009 and December 2011...
May 15, 2017: International Journal of Cardiology
Amin Daoulah, Amir Lotfi, Mushabab Al-Murayeh, Salem Al-Kaabi, Salem M Al-Faifi, Osama E Elkhateeb, Mohamed N Alama, Ahmad S Hersi, Ciaran M Dixon, Waleed Ahmed, Mohamed Al-Shehri, Ali Youssef, Ahmed Moustafa Elimam, Ayman S Abougalambou, Waheed Murad, Alawi A Alsheikh-Ali
Epidemiologic evidence suggests a link between psychosocial risk factors such as marital status and coronary artery disease (CAD). Polygamy (multiple concurrent wives) is a distinct marital status practiced in many countries in Asia and the Middle East, but its association with CAD is not well defined. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period from April 1, 2013, to March 30, 2014. Of 1,068 enrolled patients, 687 were married men...
2017: International Journal of Vascular Medicine
Rasmieh Alzeidan, Fatemeh Rabiee, Ahmed Mandil, Ahmad Hersi, Amel Fayed
OBJECTIVES: To assess the prevalence of noncommunicable disease (NCD) risk factors among Saudi university employees and their families; to estimate the cardiovascular risk (CVR) amongst the study population in the following 10years. METHODS: The NCD risk factors prevalence was estimated using a cross-sectional approach for a sample of employees and their families aged ≥ 18 years old, in a Saudi university (Riyadh in Kingdom of Saudi Arabia; KSA). WHO STEPwise standardized tools were used to estimate NCD risk factors and the Framingham Coronary Heart Risk Score calculator was used to calculate the CVR...
2016: PloS One
Abdullah S Al Saleh, Khalid F Alhabib, Alawi A Alsheik-Ali, Khadim Sulaiman, Hussam Alfaleh, Shukri Alsaif, Wael Al Mahmeed, Nidal Asaad, Haiham Amin, Ahmed Al-Motarreb, Jassim Al Suwaidi, Ahmad S Hersi
BACKGROUND: Little is known about the predictors and prognostic impact of recurrent in-hospital ischemia and infarction in patients with acute coronary syndrome (ACS). Our objectives were to determine the baseline characteristics, risk factors, and long-term outcomes of patients with recurrent myocardial infarction (Re-MI). METHODS: We evaluated patients with ACS who were enrolled in the second Gulf Registry of Acute Coronary Events from October 2008 to June 2009...
October 26, 2016: Angiology
Angel Arenal, Alessandro Proclemer, Axel Kloppe, Maurizio Lunati, José Bautista Martìnez Ferrer, Ahmad Hersi, Marcin Gulaj, Maurits C E F Wijffels, Elisabetta Santi, Laura Manotta, Lorenza Mangoni, Maurizio Gasparini
AIMS: A long-detection interval (LDI) (30/40 intervals) has been proved to be superior to a standard-detection interval (SDI) (18/24 intervals) in terms of reducing unnecessary implantable cardioverter defibrillator (ICD) therapies. To better evaluate the different impact of LDI and anti-tachycardia pacing (ATP) on reducing painful shocks, we assessed all treated episodes in the ADVANCE III trial. METHODS AND RESULTS: A total of 452 fast (200 ms < cycle length ≤ 320 ms) arrhythmic episodes were recorded: 284 in 138 patients in the SDI arm and 168 in 82 patients in the LDI arm (106/452 inappropriate detections)...
November 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Jean-Louis Excler, Christopher J Delvecchio, Ryan E Wiley, Marni Williams, In-Kyu Yoon, Kayvon Modjarrad, Mohamed Boujelal, Vasee S Moorthy, Ahmad Salah Hersi, Jerome H Kim
Middle East respiratory syndrome (MERS) remains a serious international public health threat. With the goal of accelerating the development of countermeasures against MERS coronavirus (MERS-CoV), funding agencies, nongovernmental organizations, and researchers across the world assembled in Riyadh, Saudi Arabia, on November 14-15, 2015, to discuss vaccine development challenges. The meeting was spearheaded by the Saudi Ministry of Health and co-organized by the International Vaccine Institute, South Korea. Accelerating the development of a preventive vaccine requires a better understanding of MERS epidemiology, transmission, and pathogenesis in humans and animals...
August 2016: Emerging Infectious Diseases
Hussam AlFaleh, Abdelfatah A Elasfar, Anhar Ullah, Khalid F AlHabib, Ahmad Hersi, Layth Mimish, Ali Almasood, Saleh Al Ghamdi, Abdullah Ghabashi, Asif Malik, Gamal A Hussein, Mushabab Al-Murayeh, Ahmed Abuosa, Waleed Al Habeeb, Tarek S Kashour
BACKGROUND: Little is know about the outcomes of acute heart failure (AHF) with acute coronary syndrome (ACS-AHF), compared to those without ACS (NACS-AHF). METHODS: We conducted a prospective registry of AHF patients involving 18 hospitals in Saudi Arabia between October 2009 and December 2010. In this sub-study, we compared the clinical correlates, management and hospital course, as well as short, and long-term outcomes between AHF patients with and without ACS...
May 20, 2016: BMC Cardiovascular Disorders
Hussam AlFaleh, Abdelfatah A Elasfar, Anhar Ullah, Khalid F AlHabib, Ahmad Hersi, Layth Mimish, Ali Almasood, Saleh Al Ghamdi, Abdullah Ghabashi, Asif Malik, Gamal A Hussein, Mushabab Al-Murayeh, Ahmed Abuosa, Waleed Al Habeeb, Tarek Kashour
AIMS: The aim of this study was to compare the clinical features, predictors, and clinical outcomes of patients hospitalized with acute heart failure (AHF), with and without worsening heart failure (WHF). METHODS AND RESULTS: We used data from a multicentre prospective registry of AHF patients created in Saudi Arabia. WHF was defined as recurrence of heart failure symptoms or signs-with or without cardiogenic shock. In-hospital short- and long-term outcomes, as well as predictors of WHF are described...
August 2017: European Journal of Heart Failure
Alawi A Alsheikh-Ali, Ahmad S Hersi, Adel K S Hamad, Ahmed R Al Fagih, Faisal M Al-Samadi, Abdulmohsen M Almusaad, Fayez A Bokhari, Fawzia Al-Kandari, Bandar S Al-Ghamdi, Najib Al Rawahi, Nidal Asaad, Salem Alkaabi, Amin Daoulah, Hosam A Zaky, Omer Elhag, Yahya S Al Hebaishi, Raed Sweidan, Haitham Alanazi, David Chase, Hani Sabbour, Mohammad Al Meheiri, Ismail Al Abri, Mohammad Amin, Khaled Dagriri, Adil O Ahmed, Azam Shafquat, Shahul Hameed Khan
BACKGROUND: The implantable cardioverter-defibrillator (ICD) is effective in the prevention of sudden cardiac death in high-risk patients. Little is known about ICD use in the Arabian Gulf. We designed a study to describe the characteristics and outcomes of patients receiving ICDs in the Arab Gulf region. METHODS: Gulf ICD is a prospective, multi-center, multinational, and observational study. All adult patients 18 years or older, receiving a de novo ICD implant and willing to sign a consent form will be eligible...
October 2015: Heart Views: the Official Journal of the Gulf Heart Association
Khalid F AlHabib, Kadhim Sulaiman, Jassim Al Suwaidi, Wael Almahmeed, Alawi A Alsheikh-Ali, Haitham Amin, Mohammed Al Jarallah, Hussam F Alfaleh, Prashanth Panduranga, Ahmad Hersi, Tarek Kashour, Zohair Al Aseri, Anhar Ullah, Hani B Altaradi, Kazi Nur Asfina, Robert C Welsh, Salim Yusuf
BACKGROUND: Little is known about Emergency Medical Services (EMS) use and pre-hospital triage of patients with acute ST-elevation myocardial infarction (STEMI) in Arabian Gulf countries. METHODS: Clinical arrival and acute care within 24 h of STEMI symptom onset were compared between patients transferred by EMS (Red Crescent and Inter-Hospital) and those transferred by non-EMS means. Data were retrieved from a prospective registry of 36 hospitals in 6 Arabian Gulf countries, from January 2014 to January 2015...
2016: PloS One
Tarek Seifaw Kashour, Abdulaziz Joury, Abdullah M Alotaibi, Mahmoud Althagafi, Aws S Almufleh, Ahmad Hersi, Lukman Thalib
PURPOSE: Self-medication is common worldwide. However, the prevalence of sale of prescription medications without prescription and the quality of assessment and counselling provided by community pharmacists to cardiac patients is unknown. We sought to determine the prevalence of prescription medication sales and explore how pharmacists assess and counsel patients with acute cardiac conditions. METHODS: Six hundred community pharmacies in the two largest cities in Saudi Arabia were selected...
March 2016: European Journal of Clinical Pharmacology
Hussam F AlFaleh, Lukman Thalib, Tarek Kashour, Ahmad Hersi, Layth Mimish, Abdelfatah A Elasfar, Ali Almasood, Saleh Al Ghamdi, Abdullah Ghabashi, Asif Malik, Gamal A Hussein, Mushabab Al-Murayeh, Ahmed Abuosa, Waleed Al Habeeb, Khalid F Al Habib
We assessed sex-specific differences in clinical features and outcomes of patients with acute heart failure (AHF). The Heart function Assessment Registry Trial in Saudi Arabia (HEARTS), a prospective registry, enrolled 2609 patients with AHF (34.2% women) between 2009 and 2010. Women were older and more likely to have risk factors for atherosclerosis, history of heart failure (HF), and rheumatic heart and valve disease. Ischemic heart disease was the prime cause for HF in men and women but more so in men (P < ...
August 2016: Angiology
Hussam F AlFaleh, Alawi A Alsheikh-Ali, Anhar Ullah, Khalid F AlHabib, Ahmad Hersi, Jassim Al Suwaidi, Kadhim Sulaiman, Shukri Al Saif, Wael Almahmeed, Nidal Asaad, Haitham Amin, Ahmed Al-Motarreb, Tarek Kashour
BACKGROUND: Several risk scores have been developed for acute coronary syndrome (ACS) patients, but their use is limited by their complexity. The new Canada Acute Coronary Syndrome (C-ACS) risk score is a simple risk-assessment tool for ACS patients. This study assessed the performance of the C-ACS risk score in predicting hospital mortality in a contemporary Middle Eastern ACS cohort. HYPOTHESIS: The C-ACS score accurately predicts hospital mortality in ACS patients...
September 2015: Clinical Cardiology
Hussam F AlFaleh, Mostafa Q Al Shamiri, Anhar Ullah, Khalid F AlHabib, Ahmad Salah Hersi, Shukri AlSaif, Khalid AlNemer, Amir Taraben, Asif Malik, Ahmed M Abuosa, Mimish LA, Tarek Kashour
BACKGROUND: Saudi Arabia has a non-Saudi workers population. We investigated the differences and similarities of expatriate non-Saudi patients (NS) and Saudi nationals (SN) presenting with acute coronary syndromes (ACS) with respect to therapies and clinical outcomes. METHODS: The study evaluated 2031 of the 5055 ACS patients enrolled in the Saudi Project for Assessment of Acute Coronary Syndrome (SPACE) from 2005 to 2007. Propensity score matching and logistic regression analysis were performed to account for major imbalances in age and sex in the two groups...
2015: PloS One
Khalid F AlHabib, Tarek Kashour, Abdelfatah A Elasfar, Hussam Alfaleh, Ahmad Hersi, Mostafa Alshamiri, Fayez Alshaer, Layth Mimish, Ali Almasood, Waleed AlHabeeb, Saleh AlGhamdi, Abdullah Ghabashi, KaziNur Asfina, Hani Altaradi, Omar Alnobani, Nour Alkamel, Lukman Thalib
AIM: The heart function assessment registry trial in Saudi Arabia (HEARTS) is a national multicenter project that compared de novo versus acute-on-chronic heart failure (ACHF). METHODS AND RESULTS: This is a prospective registry in 18 hospitals in Saudi Arabia between October 2009 and December 2010. The study enrolled 2610 patients: 940 (36%) de novo and 1670 (64%) ACHF. Patients with ACHF were significantly older (62.2 vs 60 years), less likely to be males (64% vs 69%) or smokers (31...
October 2015: Angiology
Prashanth Panduranga, Kadhim J Sulaiman, Ibrahim Al-Zakwani, Khalid F Alhabib, Ahmad Hersi, Jassim Al Suwaidi, Alawi A Alsheikh-Ali, Wael Almahmeed, Shukri Al Saif, Hussam Al-Faleh, Jawad Al-Lawati, Nidal Asaad, Ahmed Al-Motarreb, Haitham Amin
We compared baseline characteristics, clinical presentation, and in-hospital outcomes between Middle Eastern Arabs and Indian subcontinent patients presenting with acute coronary syndrome (ACS). Of the 7930 patients enrolled in Gulf Registry of Acute Coronary Events II (RACE II), 23% (n = 1669) were from the Indian subcontinent. The Indian subcontinent patients, in comparison with the Middle Eastern Arabs, were younger (49 vs 60 years; P < .001), more were males (96% vs 80%; P < .001), had lower proportion of higher Global Registry of Acute Coronary Events risk score (8% vs 27%; P < ...
October 2015: Angiology
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