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Very And Rare And Tumors

Jaskaran Singh Gosal, Satyadeo Pandey, Kuntal Kanti Das, Deepak Khatri, Kamlesh Rangari, Awadhesh Kumar Jaiswal, Sanjay Behari
BACKGROUND: Pathological laughter is inappropriate, involuntary and unmotivated laughter episodes which may or may not be associated with mirth or amusement. Though associated with many diffuse brain pathologies, its association with intracranial focal mass lesions causing ventrolateral brainstem compression like petroclival meningioma is very rare. The exact pathophysiology of this interesting and unusual clinical symptom is unknown but probably involves disinhibition and release of the so-called coordination center located in the upper brainstem due to compression by the tumor...
December 13, 2018: World Neurosurgery
Aparna Harbhajanka, Wissam Dahoud, Claire W Michael, Robin Elliot
Pulmonary artery intimal sarcoma is a rare aggressive intraluminal tumor often misdiagnosed as acute or chronic pulmonary thromboembolism due to its clinical presentation and radiological findings. Thus early diagnosis is very crucial and may improve patient outcome. There is limited literature on diagnosis of pulmonary artery sarcoma by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Herein, we report a case of mass-like lesion in the PA diagnosed on cytological material obtained by EBUS-TBNA with rapid on-site evaluation (ROSE)...
December 14, 2018: Diagnostic Cytopathology
Euno Choi, Seonk-Ik Kim, Jae-Kyung Won, Chun Kee Chung, Seung Ki Kim, Seung-Hong Choi, Seongmin Choi, Bome Han, Bokyung Ahn, I M Sun-Wha, Sung-Hye Park
Multinodular and vacuolating neuronal tumor (MVNT) of the cerebrum is a recently recognized rare neuronal tumor, and its pathogenesis is unclear. We analyzed 7 cases of histologically typical MVNT: six were adults [mean age: 43.0years (range: 23-56)] and one was a child (10-year-old). The most common symptoms were seizures (n=4) and headache (n=2). The tumors were supratentorial (temporal=5 and frontal lobes=2) in origin as reported. Vacuolated tumor cells were robustly positive for alpha-INA and Olig2 and at least partly positive for synaptophysin and MAP2, but negative for Neu-N...
December 11, 2018: Human Pathology
L Sun, W Zhu, J Q Zhai, T T Yu
Hypopharyngeal carcinoma is the worst malignant tumor in the head and neck squamous cell carcinoma, which has the worst prognosis. As the hypopharynx has a rich lymphatic network, cervical lymph node metastasis is very easy to occur. Castleman disease is vascular follicular lymphnode hyperplasia, a rare chronic lymphoproliferative disease of unknown cause. In the diagnosis of Castleman disease, attention should be paid to the differential diagnosis of head and neck malignant tumors.
July 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Kumi Ohashi-Nakatani, Yasuo Shibuki, Mizuho Fujima, Reiko Watanabe, Akihiko Yoshida, Hiroshi Yoshida, Yuji Matsumoto, Takaaki Tsuchida, Shun-Ichi Watanabe, Noriko Motoi
Ectopic meningioma is a generally rare type of benign tumor that very rarely occurs in the lung. Here, we report the cytological findings of a primary pulmonary meningioma with a particular focus on immunohistochemical (IHC) assessment. A healthy 60-year-old woman visited our hospital with an asymptomatic nodule in the right lower lung lobe. She had no particular past-history and no other tumors in the central nervous system or elsewhere according to an imaging examination. Transbronchial fine-needle aspiration cytology revealed clusters of spindle cells in a whorled formation and psammoma bodies...
December 8, 2018: Diagnostic Cytopathology
Chun-Bi Chang, Kwai-Fong Ng, Yon-Cheong Wong, Shen-Yang Lee, Cheng-Keng Chuang, Li-Jen Wang
RATIONALE: Metanephric adenoma (MA) is a rare and often benign tumor. Most MAs were misdiagnosed as renal cell carcinomas (RCCs) preoperatively. Diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) mapping can help to differentiate benign and malignant tumors. However, there are still pitfalls in using DWI and ADC to discriminate benign and malignant lesions. PATIENT CONCERNS: A 56-year-old woman had a right renal metanephric adenoma. The tumor showed very low ADC value preoperatively and was misdiagnosed as a renal cell carcinoma...
December 2018: Medicine (Baltimore)
Song Guo, Hongtao Lv, Li Yan, Fengnian Rong
RATIONALE: Reports of malignant ovarian tumor with hyperamylasemia are very rare. We present a patient with hyperamylasemia who was diagnosed with a malignant ovarian tumor. PATIENT CONCERNS: A 46-year-old woman was hospitalized complaining of a 2-day history of abdominal discomfort and fever. On physical examination, she showed abdominal distention and tenderness, with rebound pain. Laboratory evaluation showed significantly elevated serum amylase levels. Computed tomography (CT) revealed a solid mass with uneven density in the pelvis...
December 2018: Medicine (Baltimore)
Xueli Wang, Fenghua Wang, Yumei Liang, Wen Chen
INTRODUCTION: Primary small cell carcinoma (SCC) after renal transplantation is very rare. Here, we reported 1 case of primary SCC after renal transplantation and analyzed its clinical and pathological characteristics. CASE PRESENTATION: A 55-year-old female underwent renal transplantation in our hospital 2 years ago and had been using tacrolimus for immunosuppressive therapy. Because of abdominal distention, the patient was admitted to our hospital. Computed tomography (CT) showed a malignant tumor of left kidney...
December 2018: Medicine (Baltimore)
Hassan Salame, Mahdi Issa, Gregory Nicolas, Juliano Haddad, Marwan M Haddad, Firas S Farhat, Hussein Moubarak, Tony Kfoury, Elie Zaghrini, Raja Wakim
BACKGROUND Gastrointestinal stromal tumors (GISTs) are rare gastrointestinal neoplasms. The spontaneous rupture of a jejunal GIST is very rare and spontaneous rupture of liver metastasis from an intestinal GIST is even rarer with only a few cases reported in the literature. CASE REPORT In this article, we reported a case of spontaneous rupture of a liver metastasis from a malignant jejunal GIST that presented with active tumoral bleeding, hypovolemic shock, and hemoperitoneum. The patient was successfully treated with arterial embolization of the tumor...
December 13, 2018: American Journal of Case Reports
Makoto Hosoya, Naoki Oishi, Masaru Noguchi, Kento Kasuya, Takanori Nishiyama, Toru Ishikawa, Ken Kasahara, Hidemi Miyazaki, Kaoru Ogawa
Schwannoma arising from the intermediate nerve is very rare, with only a few cases reported in the literature. Here, we report a rare case of a rapidly growing schwannoma that originated from the intermediate nerve in a 17-year-old woman. We performed tumor resection using the translabyrinthine approach with continuous intraoperative monitoring, in which the facial nerve root was used to evoke muscle action potential. The monitoring revealed the tumor origin and enabled complete surgical resection with the preservation of facial nerve motor function...
December 12, 2018: Journal of International Advanced Otology
Denise Buchner, Lena Hieggelke, Heike Löser, Christiane Josephine Bruns, Alexander Quaas, Markus Philipp Hussein Ghadimi
BACKGROUND: Collision tumors are rare cases with two different tumor entities growing synchronously. While adenocarcinoma of the pancreas is the most common pancreatic tumor with an incidence of 10 per 100.000, retroperitoneal liposarcoma remains very rare. This is the first report of a collision tumor between these two tumor entities. CASE PRESENTATION: Demographic details: The tumor was diagnosed in a 64 male Caucasian patient. Besides atrial fibrillation, arterial hypertension and a hypothyroidism there is no relevant medical history especially no history of cancer...
December 12, 2018: BMC Cancer
Horakova Zuzana, Velecky Lukáš, Pazourkova Marta, Urbánková Pavla, Smilek Pavel
BACKGROUND: Primary branchiogenic carcinoma (BC) is an exceptional diagnostic entity. In most cases, suspicion of BC is confirmed to be a cystic lymph node metastasis of an occult primary tumor. Martin and Khafif therefore established diagnostic criteria, emphasizing above all the importance of a histologically assessed transformation of cystic lining epithelium into an invasive squamous cell carcinoma in one pathological lesion after the exclusion of a primary tumor. CASE REPORT: We present a case report of an 80-year-old patient who presented for a follow-up for an 8-year history of a benign lateral cervical cyst, which was not surgically treated due to the patients high risk of complications from general anesthesia...
2018: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
Horakova Zuzana, Slavik Marek, Vesely Karel, Binkova Hana, Smilek Pavel
BACKGROUND: Breast cancer (BC) is a frequent malignant disease which tends to develop distant metastases, but only very rarely in the head and neck region. CASE REPORT: We present two case reports of patients with metastases of invasive BC in this area. They are of different clinical manifestation with different time relation to the primary tumor and different symptomatology. In the case of the first patient, a few years without evidence of malignant disease after treatment of primary tumor in complete remission...
2018: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
Madson Q Almeida, Joao Evangelista Bezerra-Neto, Berenice B Mendonça, Ana Claudia Latronico, Maria Candida B V Fragoso
Malignancy must be considered in the management of adrenal lesions, including those incidentally identified on imaging studies. Adrenocortical carcinomas (ACCs) are rare tumors with an estimated annual incidence of 0.7-2 cases per year and a worldwide prevalence of 4-12 cases per million/year. However, a much higher incidence of these tumors (>15 times) has been demonstrated in south and southeastern Brazil. Most ACCs cause hypersecretion of steroids including glucocorticoids and androgens. ACC patients have a very poor prognosis with a 5-year overall survival (OS) below 30% in most series...
December 10, 2018: Clinics
Komkrit Ruangritchankul, Steve Connor, Richard Oakley
Oncocytic sialolipoma is a very rare tumor of which only three cases have been reported. This entity is considered to be a variant of sialolipoma which harbours oncocytic nodules within a well-circumscribed lipomatous mass. We report a parotid mass in 73-year-old female that was difficult to diagnose in imaging and on biopsy. Ultrasonography and MRI demonstrated a mass with features thought to be consistent with lipoma. Twice needle core biopsies were performed. Both were indefinite for diagnosis. The first report favoured a lipoma and the second report suggested the lesion represented oncocytic hyperplasia or an oncocytoma...
December 11, 2018: Head and Neck Pathology
Manish Sahni, Ashish Goel, Pankaj Pande, Kapil Kumar
Multiple gastrointestinal cancers in a single patient is a rare entity. In our study, we are showing the clinical presentation and management of these patients. A fifty-nine-year-old asthenic male (already treated case of metachronous colorectal cancer in 2008 and 2011) presented with complaints of generalized weakness and fatigue. Strong family history was present with two of his first-degree relatives having diagnosed with gastrointestinal cancer at the age < 50 years with one of them having stomach carcinoma and another with GEJ tumors...
December 2018: Indian Journal of Surgical Oncology
Garima Daga, Rajiv Paul, Ghanashyam Mandal, Rajeev Kumar
Malignant peripheral nerve sheath tumor (MPNST) refers to spindle cell sarcomas arising from or separating in the direction of cells of peripheral nerve sheath. The MPNST of the parotid gland is an extremely rare tumor, accounts for < 5% of all soft tissue sarcomas, and carries a poor prognosis. In this article, we report a case of MPNST of parotid gland in a 45-year-old male and review its diagnostic and therapeutic challenges. A 45-year-old male presented with right parotid swelling for 2 years with rapid increase in size over the last 3 months...
December 2018: Indian Journal of Surgical Oncology
A P Roshini, Rakesh Ramesh, T Rajalakshmi
Multiple primary cancer (MPC) has an incidence of 1.8% and is defined as having two or more cancers in a single patient. Synchronous tumors are defined as ≥ 2 primary tumors occurring within 6 months of diagnosis of the first primary tumor. We present a case of a 27-year-old female patient who presented with a painless, gradually progressive right-sided neck swelling for the last 1 year with no systemic complaints. Examination revealed a 4 × 3-cm, firm, smooth surfaced swelling on right lobe of thyroid...
December 2018: Indian Journal of Surgical Oncology
Prashant Balwant Kerkar, Garima Daga
Extraskeletal osteosarcomas are extremely rare and account for < 1% of the soft tissue sarcomas. Most common site is in soft tissues of the lower extremities. Primary osteosarcomas of the breast are extremely rare and only a few cases have been reported in literature. It carries a very dismal prognosis in view of its high rate of local recurrence and distant spread. We report a case of primary osteosarcoma of the breast. A 44-year-old female presented with a 14 × 10 cm solid mass in right breast...
December 2018: Indian Journal of Surgical Oncology
Ashish Sachan, Hirdaya H Nag, Neha Nischal, Sandip Barman, Ravindra K Saran, Phani K Nekarakanti, Ashok Sharma
Solid pseudopapillary neoplasm is a rare tumor of the pancreas. These tumors are considered to have low malignant potential with good prognosis. Due to its rarity, details about clinical presentation and management of the disease are not very clear. This study aims to share our experience and to describe management of the disease. We retrospectively evaluated patients 13 patients diagnosed with SPT on histopathological examination of resected specimen. Data on their clinicopathological, management-related factors, and follow-up was collected...
December 2018: Indian Journal of Surgical Oncology
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