keyword
MENU ▼
Read by QxMD icon Read
search

Diabetes AND Ulcers

keyword
https://www.readbyqxmd.com/read/30537019/lipophagy-in-nonliver-tissues-and-some-related-diseases-pathogenic-and-therapeutic-implications
#1
REVIEW
Kebing Zhou, Pingbo Yao, Jun He, Hong Zhao
Lipid autophagy (lipophagy) is defined as a selective autophagy process in which some intracellular lipid droplets are selectively degraded by autophagic lysosomes pathway. The occurrence of lipophagy was first discovered in liver tissues. Additionally, abundant evidence indicated that the occurrence of hepatic lipophagy has been implicated in many liver diseases including fatty liver diseases, nonalcoholic fatty liver diseases, liver fibrosis, and liver cirrhosis. However, recent studies suggested that hepatic lipophagy occurs not only in liver tissue but also in other nonliver tissues and cells...
December 10, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/30534807/histopathological-changes-in-major-amputations-due-to-diabetic-foot-a-review
#2
Diana Gherman, Cristiana Iulia Dumitrescu, Andra Ciocan, Carmen Stanca Melincovici
Diabetes mellitus is the leading cause of non-traumatic amputations worldwide. Ulcer of the diabetic foot is one of the most prevalent lesions of diabetic patients and it occurs in the natural evolution of the disease as a tardive complication. Neuropathy is the main determinant of foot ulcer. A key role is played by the loss of sensitive nerves, which prove to be a protective barrier against high pressure applied otherwise on the foot. The morphopathological characteristics of neuropathic lesions in patients with diabetes show important improvement associated with the pressure relieving treatment strategies...
2018: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/30531767/intralesional-and-perilesional-application-of-an-epidermal-growth-factor-heberprot-p%C3%A2-in-diabetic-foot-ulcers-part-one
#3
Jose Fernandez Montequin, Llipsy Santiesteban Bonachea, Jorge Berlanga Acosta, C V Peres, W S Gutierres, G A Duarte
For 15 years, from 2001, we began to apply Heberprot-P®, an injectable Epidermal Growth Factor (0.75 μg) created in the Center of Biotechnology, in Havana, Cuba. More than 159,000 patients were treated around the world, from 25 countries, with, with only 9-11% high-level amputations. In this paper, we discuss our experience in the treatment of the most complex diabetic foot ulcers cases for the last 15 years.
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/30527940/influence-of-multiple-stents-on-periprocedural-stroke-after-carotid-artery-stenting-in-the-carotid-revascularization-endarterectomy-versus-stent-trial-crest
#4
Brajesh K Lal, Gary S Roubin, Michael Jones, Wayne Clark, Ariane Mackey, Michael D Hill, Jenifer H Voeks, George Howard, Robert W Hobson, Thomas G Brott
BACKGROUND: In the Carotid Revascularization Endarterectomy versus Stent Trial (CREST), carotid artery atherosclerotic lesion length and nature of the lesions were important factors that predicted the observed difference in stroke rates between carotid endarterectomy and carotid artery stenting (CAS). Additional patient-related factors influencing CAS outcomes in CREST included age and symptomatic status. The importance of the operator's proficiency and its influence on periprocedural complications have not been well defined...
December 4, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/30526987/a-57-year-old-man-with-subacute-progressive-hemoptysis-and-fevers
#5
Andrew Sumarsono, Timothy J Brown, Stan D Atkin, Jason Clark
A 57-year-old man was admitted for 1 month of accelerating hemoptysis and hematemesis. Two weeks earlier, he first presented with fevers and hemoptysis of 2 weeks' duration and was diagnosed with community-acquired pneumonia treated with 5 days of ceftriaxone and azithromycin. He improved and was discharged, but his hemoptysis recurred 1 day after discharge and progressed over 9 days, leading to the present admission. He endorsed an 5-kg weight loss, daily fevers up to 39.4°C, and night sweats since discharge...
December 2018: Chest
https://www.readbyqxmd.com/read/30525053/corneal-subbasal-nerve-plexus-changes-in-severe-diabetic-charcot-foot-deformity-a-pilot-study-in-search-for-a-dnoap-biomarker
#6
Anica Herlyn, Ruby Kala Prakasam, Sabine Peschel, Stephan Allgeier, Bernd Köhler, Karsten Winter, Rudolf F Guthoff, Thomas Mittlmeier, Oliver Stachs
Introduction: Diabetic neuroosteoarthropathy (DNOAP) early symptoms are unspecific, mimicking general infectious symptoms and rendering a diagnosis challenging. Consequently, unfavourable outcomes occur frequently, with recurrent foot ulceration, infectious complications, and eventually amputation. Corneal confocal microscopy (CCM) of the subbasal nerve plexus (SNP) is used to detect early peripheral neuropathy in diabetic patients without diabetic retinopathy. This pilot study was designed to determine if specific SNP changes manifest in severe DNOAP in comparison to a healthy control group...
2018: Journal of Diabetes Research
https://www.readbyqxmd.com/read/30517549/diabetic-foot-ulcers-with-myiasis-a-potential-route-for-resistance-gene-dissemination-for-enterococci
#7
Felipe Tavares Rodrigues, Valéria Magalhães Aguiar, Claudia Soares Lessa
No abstract text is available yet for this article.
November 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/30517410/degree-of-risk-for-foot-ulcer-due-to-diabetes-nursing-assessment
#8
Maria do Livramento Saraiva Lucoveis, Mônica Antar Gamba, Maria Angela Boccara de Paula, Ana Beatriz Pinto da Silva Morita
OBJECTIVE: To classify the level of risk for foot ulcers in people with diabetes mellitus and identify their main predictive risk factors. METHOD: Exploratory, descriptive study, in which patients were assessed in a municipal ambulatory of São Paulo through nursing consultation, following the guidelines of the International Consensus on the Diabetic Foot. Data were descriptively analyzed. RESULTS: The analyzed population was composed of 50 longevous and retired people, with household income of up to two minimum wages, with dermato-neurofunctional risk factors and unfavorable clinical indicators, and 66% had Risk 1; 16% Risk 2; 6% Risk 3 and 12% Risk 4...
November 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/30517288/effects-of-nanoparticles-of-hydroxy-aluminum-phthalocyanine-on-markers-of-liver-injury-and-glucose-metabolism-in-diabetic-mice
#9
M A B Melo, W Caetano, E L Oliveira, P M Barbosa, A L B Rando, M M D Pedrosa, V A F Godoi
Photodynamic therapy, by reducing pain and inflammation and promoting the proliferation of healthy cells, can be used to treat recurrent lesions, such as diabetic foot ulcers. Studies using the photosensitizer phthalocyanine, together with the nanostructured copolymeric matrix of Pluronic® and Carbopol® for the treatment of diabetic foot ulcers and leishmaniosis lesions, are showing promising outcomes. Despite their topical or subcutaneous administration, these molecules are absorbed and their systemic effects are unknown...
December 3, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/30516496/-the-local-registry-data-on-myocardial-infarction-in-women-the-risk-factor-analysis-clinical-characteristics-and-survival
#10
M Hrebenyk, L Zelenenka, L Zoria, S Maslii
The clinical experience implies poor prognosis in women with myocardial infarction (MI). We performed a retrospective cohort study of 1395 patients - 987 (70,75%) men and 408 (29,25%) women) aged of 64,63±11,43 years with myocardial infarction and comorbidity hospitalized between 2010-2016. This study shows an increase of mortality in women with myocardial infarction during the last 4 years from 23,1% to 34,2%. We observed more frequent cases of non-STEMI (p=0,014) and recurrent myocardial infarction in females compared with males (р<0,0001)...
October 2018: Georgian Medical News
https://www.readbyqxmd.com/read/30513132/motivational-interviewing-as-an-intervention-to-improve-adherence-behaviours-for-the-prevention-of-diabetic-foot-ulceration-a-systematic-review
#11
REVIEW
Jodi Binning, Jim Woodburn, Sicco Bus, Ruth Barn
Diabetic foot ulceration is a major complication associated with high morbidity. Little evidence exists on which interventions are effective at preventing ulceration. Participants who are adherent to self-care behaviours have significantly better outcomes. Motivational interviewing is an intervention that has been used successfully for conditions where adherence is important, such as reduction of obesity and HbA1c levels. A systematic review was conducted to determine whether motivational interviewing is effective at improving adherence for the prevention of Diabetic Foot Ulceration...
December 4, 2018: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/30507549/managing-patients-with-diabetic-foot-ulcers
#12
Laura Bolton
Diabetic foot ulcers (DFUs) remain a challenge for clinicians despite decades of study. Clinicians now realize that healing strategies should focus on the patient as well as the ulcer. The search continues for interventions that affected individuals and their care providers can count on to heal and manage these challenging wounds, stopping the dreaded progression to amputation and death. The path to healing a patient's DFU often requires multidisciplinary care, including consistent offloading of insensate areas, endocrinologic and metabolic control, and improved circulation...
December 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30498354/efficacy-of-negative-pressure-wound-therapy-using-vacuum-assisted-closure-combined-with-photon-therapy-for-management-of-diabetic-foot-ulcers
#13
Xiaoxiao Hu, Weishuai Lian, Xiaojun Zhang, Xue Yang, Jinxia Jiang, Maoquan Li
Background: Diabetes mellitus, one of the most prevalent chronic metabolic diseases, causes many complications. Among the complications, one of the most common chronic complications is diabetic foot ulcers (DFUs). Objective: This study was conducted to investigate the efficacy of negative pressure wound therapy using vacuum-assisted closure (VAC) combined with photon therapy for the management of DFUs. Patients and methods: The study included a total of 69 patients with DFUs during the period from January 2014 to December 2015...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/30498174/assessment-of-sirtuin-3-and-sirtuin-4-level-in-patients-with-diabetes-mellitus-and-periodontitis-a-clinical-study
#14
Rashmi Laddha, Monica Mahajania, Amruta Khadse, Rajat Bajaj, Rashmi Jawade, Shashwati Choube
AIM: Periodontitis is considered as infection in periodontal supporting structure leading to tooth mobility and ulcerated periodontal pockets. The present study was conducted to assess Sirtuin 3 (SIRT 3) and SIRT 4 level in patients with diabetes mellitus (DM) and periodontitis. MATERIALS AND METHODS: The present study was conducted on 60 subjects. Subjects were divided into four groups, groups I to IV. Each group comprised of 15 subjects. In all subjects, fasting blood glucose level was assessed...
October 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/30496896/extracorporeal-shockwave-therapy-for-diabetic-foot-ulcers-a-systematic-review-and-meta-analysis
#15
REVIEW
L H Hitchman, J P Totty, A Raza, P Cai, G E Smith, D Carradice, T Wallace, A E Harwood, I C Chetter
OBJECTIVES: To assess the current available evidence examining the efficacy of extracorporeal shockwave therapy (ESWT) on healing of diabetic foot ulcers (DFU). DATA SOURCES: PubMed, Ovid MEDLINE, Web of Science, Embase, CINAHL Plus, Cochrane Central Registry of Controlled Trials and Clinical Trials Registry electronic databases were searched up to November 2017 for terms related to ESWT in DFU. REVIEW METHODS: Articles were identified and data extracted by two independent reviewers onto Review Manager 5...
November 26, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30487975/testing-the-sympathetic-nervous-system-of-the-foot-has-a-high-predictive-value-for-early-amputation-in-patients-with-diabetes-with-a-neuroischemic-ulcer
#16
Sanne M Schreuder, M Nieuwdorp, Marc J W Koelemay, Shandra Bipat, Jim A Reekers
Objective: There is evidence from the literature that dysfunctionality of the sympathetic nervous system of the foot with subsequent loss of local autoregulation could be a predictor of early amputation in patients with diabetes with a neuroischemic ulcer. To confirm this we tested the functionality of the sympathetic nervous system in the foot in a consecutive group of 31 patients with diabetes with critical limb ischemia and non-healing neuroischemic ulcer. Research design and methods: Prospective cohort with retrospective analysis after 12 months of routinely acquired clinical data...
2018: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/30484414/prevalence-of-extended-spectrum-%C3%AE-lactamases-in-multi-drug-resistant-pseudomonas-aeruginosa-from-diabetic-foot-patients
#17
Faaiz Ul Hassan, Muhammad Suhaib Qudus, Sheikh Arslan Sehgal, Jawad Ahmed, Momin Khan, Khayam Ul Haq, Shahina Mumtaz, Muhammad Arshad, Sami Siraj
BACKGROUND: Pseudomonas aeruginosa is one of the major pathogen associated with acute tissue damage in patients with diabetic foot ulcer (DFU). Antibiotic resistance in P. aeruginosa often bodes unpredictable and unfavourable clinical outcomes, owing to a variety of intrinsic and acquired molecular mechanisms. The study aimed to determine the frequency of ESBLs in Multi-drug resistant P. aeruginosa from diabetic foot patients. METHOD: Present study's duration was one year and 100 patients with DFU were enrolled...
November 27, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/30479667/validation-of-a-weight-bearing-ankle-equinus-value-in-older-adults-with-diabetes
#18
A Searle MOsteo, M J Spink, V H Chuter
Background: Accurate measurement of ankle joint dorsiflexion is clinically important as a restriction has been linked to many foot and ankle pathologies, as well as increased ulcer risk and delayed ulcer healing in people with diabetes. Use of the reliable weight bearing (WB) Lunge test is limited as normal and restricted ranges for WB ankle joint dorsiflexion are not identified. Additionally the extent of WB dorsiflexion restriction that results in clinically adverse outcomes is unclear...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/30475216/honey-dressing-on-a-leg-ulcer-with-tendon-exposure-in-a-patient-with-type-2-diabetes
#19
Ilaria Teobaldi, Vincenzo Stoico, Fabrizia Perrone, Massimiliano Bruti, Enzo Bonora, Alessandro Mantovani
Honey has been used as a wound dressing for hundreds of years by ancient civilizations, but only recently it has acquired scientific interest because of its relevant biological properties. In the last decade, indeed, several trials and observational studies have reported that, compared to conventional treatment (e.g. antiseptics, polyurethane film, paraffin gauze, soframycin-impregnated gauze), honey dressings seem to be better in healing time of different types of wounds, including diabetic foot ulcers. However, to date, information about a potential favorable biological effect of honey dressings on diabetic ulcers with exposed tendon are still scarce...
November 16, 2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/30470448/self-reported-physical-activity-in-community-dwelling-adults-with-diabetes-and-its-association-with-diabetes-complications
#20
Nathan A Johnson, Alex L Barwick, Angela Searle, Martin J Spink, Stephen M Twigg, Vivienne H Chuter
AIMS: To describe the physical activity levels of an Australian community-based adult population with diabetes, and investigate the interaction between diabetes complications and physical activity. METHODS: Anthropometric, demographic, biochemical and self-reported physical activity measures (IPAQ) were performed. Associations and multiple regression analyses were undertaken between physical activity, known risk factors for diabetes complications, and history of cardiovascular disease (CVD), neuropathy and foot ulceration obtained from medical records...
November 4, 2018: Journal of Diabetes and its Complications
keyword
keyword
169183
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"