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https://www.readbyqxmd.com/read/30545550/deletion-of-macro-domain-containing-2-macro-d2-associated-with-transient-hydrops-fetalis
#1
I Uzun Çilingir, N C Sayin, H Gurkan, N A Çiftdemir, E Atlı, C İnan, S Erzincan, H Sutcu, U Vatansever, F Varol
No abstract text is available yet for this article.
December 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/30535072/clinical-presentation-and-survival-of-childhood-hypertrophic-cardiomyopathy-a-retrospective-study-in-united-kingdom
#2
Gabrielle Norrish, Ella Field, Karen Mcleod, Maria Ilina, Graham Stuart, Vinay Bhole, Orhan Uzun, Elspeth Brown, Piers E F Daubeney, Amrit Lota, Katie Linter, Sujeev Mathur, Tara Bharucha, Khoon Li Kok, Satish Adwani, Caroline B Jones, Zdenka Reinhardt, Juan Pablo Kaski
Aims: Understanding the spectrum of disease, symptom burden and natural history are essential for the management of children with hypertrophic cardiomyopathy (HCM). The effect of changing screening practices over time has not previously been studied. This study describes the clinical characteristics and outcomes of childhood HCM over four decades in a well-characterized United Kingdom cohort. Methods and results: Six hundred and eighty-seven patients with HCM presented at a median age of 5...
December 6, 2018: European Heart Journal
https://www.readbyqxmd.com/read/30501905/the-efficiency-of-the-symptom-based-score-in-infants-diagnosed-with-cow-s-milk-protein-and-hen-s-egg-allergy
#3
Seda Sirin Kose, G Atakul, S Asilsoy, N Uzuner, O Anal, O Karaman
INTRODUCTION AND OBJECTIVES: Symptom-based score (SBS) quantifies the number and severity of suspected cow's milk-related symptoms. In this study, we aimed to evaluate the efficiency of SBS in patients diagnosed with cow's milk protein (CMPA) and hen's egg allergy (HEA). MATERIALS AND METHODS: A single-center study was conducted between June 2015 and August 2017. Infants who were diagnosed with CMPA and HEA or both were enrolled in the study. SBS was applied at baseline and at one month during an elimination diet...
November 27, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/30412694/the-current-clinical-and-geographical-situation-of-cutaneous-leishmaniasis-based-on-species-identification-in-turkey
#4
Ahmet Özbilgin, Seray Töz, Mehmet Harman, Suhan Günaştı Topal, Soner Uzun, Fulya Okudan, Dilek Güngör, Ayşegül Erat, Hatice Ertabaklar, Sema Ertuğ, Cumhur Gündüz, İbrahim Çavuş, Mehmet Karakuş, İpek Östan Ural, M Kirami Ölgen, Çağla Kayabaşı, Özgür Kurt, Yusuf Özbel
Leishmaniases are a group of vector-borne diseases caused by the members of Leishmania genus, and there are three main clinical forms of the infection as visceral, cutaneous, and mucocutaneous. Cutaneous leishmaniasis is a growing public health problem in Turkey due to increasing detection of autochthonous cases caused by L. major and L. donovani in some regions in addition to Syrian imported cases. For this reason, we aimed to evaluate the current epidemiological situation of CL in the view of causative agents and their geographical distribution throughout Turkey...
November 6, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30384291/removal-of-wastewater-and-polymer-derived-n-nitrosodimethylamine-precursors-with-integrated-use-of-chlorine-and-chlorine-dioxide
#5
Habibullah Uzun, Daekyun Kim, Tanju Karanfil
In this study, the effects of five different pre-oxidation scenarios (i.e., individual, simultaneous, and sequential applications of chlorine dioxide [ClO2 ] and chlorine [Cl2 ]) on the removal of N-nitrosodimethylamine (NDMA) formation potential (FP) from different water matrices (i.e., non-impacted natural waters, wastewater [WW]-impacted, and polymer-impacted waters) with subsequent chloramination were investigated. Practically relevant doses of ClO2 and Cl2 were applied for all scenarios to avoid the formation of disinfection by-products (DBPs) at regulatory levels...
February 2019: Chemosphere
https://www.readbyqxmd.com/read/30368740/predictors-of-unfavorable-outcome-in-neurosyphilis-multicenter-id-iri-study
#6
Derya Ozturk-Engin, Hakan Erdem, Rodrigo Hasbun, Shu-Hua Wang, Hulya Tireli, Pierre Tattevin, Xavier Argemi, Enora Ouamara-Digue, Andrea Gombos, Botond Lakatos, Fatma Sırmatel, Yasemin Cag, Abdullah Umut Pekok, Seniha Senbayrak, Ilker Inanç Balkan, Marie Gheno, Nuray Uzun, Selçuk Kaya, Gönül Cicek-Senturk, Gönül Şengöz, Recep Tekin, Mustafa Kemal Çelen, Saygın Nayman-Alpat, Pınar Ergen, Alper Şener, Canan Agalar, Sükran Köse, Ahmet Çagkan Inkaya, Figen Kaptan, Fahad Al-Majid, Umit Savasci, Haluk Vahaboglu
Neurosyphilis (NS) has different clinical manifestations and can appear during any stage of syphilis. We aimed to identify the factors affecting poor outcome in NS patients. Patients with positive cerebrospinal fluid Venereal Disease Research Laboratory test, and positive serological serum treponemal or nontreponemal tests were classified as definite NS. The data of 141 patients with definite NS were submitted from 22 referral centers. Asymptomatic NS, syphilitic meningitis, meningovascular syphilis, tabes dorsalis, general paresis, and taboparesis were detected in 22 (15...
October 27, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/30321789/the-relation-of-fetal-colon-and-rectum-diameters-with-labor-in-healthy-late-third-trimester-pregnancies
#7
Cihan Inan, N Cenk Sayin, Z Nihal Dolgun, Selen Gursoy Erzincan, Isil Uzun, Havva Sutcu, Fusun Varol
OBJECTIVE: To investigate the associations of fetal colon-rectum diameters with labor and fetal distress or meconium passage in healthy pregnancies in the late 3rd trimester. STUDY DESIGN: A total of 162 healthy, singleton pregnant women at ≥360/7 weeks who were in the latent-phase of labor (n = 69) or those not in labor (n = 93, controls) at the time of ultrasound examination were enrolled. Fetal colon (ascending, transverse, descending, sigmoid) and rectum diameters, Doppler indices of materno-fetal vessels were measured...
October 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30280507/alterations-in-cerebral-blood-flow-in-children-with-congestive-heart-failure-due-to-ventricular-septal-defect
#8
Nurdan Ozturk Tasar, Pelin Kosger, Nevzat Uzuner, Birsen Ucar
OBJECTIVE: We aimed to investigate the effect of ventricular septal defect (VSD) and heart failure on cerebral blood flow (CBF) in children, whether heart failure treatment improves CBF, and if there is any relationship between CBF and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) level. METHOD: Forty children with VSD (13 with heart failure) aged between 1 and 36 months were studied. The control group comprised 25 healthy children in the same age group...
October 2, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30238582/angioedema-is-an-unfavorable-factor-for-the-response-to-omalizumab-in-chronic-spontaneous-urticaria-a-retrospective-study
#9
Gamze Serarslan, Mehmet Uzun, Asena Çiğdem Doğramacı, Ebru Çelik
Antihistamines are the first-line treatment option for chronic urticaria. In recent years, omalizumab, an anti-immunoglobulin-E humanized monoclonal antibody, has been used in patients with recalcitrant disease. The present study aimed to retrospectively evaluate the efficacy and safety of omalizumab and determine whether there was a difference between complete and partial responses to omalizumab with respect to age, gender, disease duration and coexistence of angioedema. From May 2014 to December 2016, a total of 40 refractory chronic urticaria patients were treated with omalizumab...
September 20, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/30213376/corrigendum-to-symptom-severity-prediction-from-neuropsychiatric-clinical-records-overview-of-2016-cegs-n-grid-shared-tasks-track-2-j-biomed-inform-2017-nov-75s-s62-s70
#10
Michele Filannino, Amber Stubbs, Özlem Uzuner
No abstract text is available yet for this article.
September 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/30159625/outbreak-of-shiga-toxin-producing-escherichia-coli-associated-hemolytic-uremic-syndrome-in-istanbul-in-2015-outcome-and-experience-with-eculizumab
#11
Ayşe Ağbaş, Nilüfer Göknar, Nurver Akıncı, Zeynep Yürük Yıldırım, Mehmet Taşdemir, Meryem Benzer, İbrahim Gökçe, Cengiz Candan, Nuran Küçük, Selçuk Uzuner, Gül Özçelik, Demet Demirkol, Lale Sever, Salim Çalışkan
BACKGROUND: This study aims to identify epidemiological and clinical characteristics of patients and report our experience with eculizumab treatment during an outbreak of hemolytic uremic syndrome (HUS) caused by Shiga toxin-producing Escherichia coli (STEC) in Istanbul in 2015. METHODS: Thirty-two children (21 females, median age 3.25 years) were included in this study. Demographic, clinical and laboratory data, and treatment details were retrospectively collected...
December 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/30102479/knowledge-levels-related-to-allergen-specific-immunotherapy-and-perspectives-of-parents-whose-children-were-diagnosed-with-asthma-and-or-allergic-rhinitis-in-turkey
#12
Sakine Işık, Şule Çağlayan-Sözmen, Suna Asilsoy, Serdar Kamer Kılıçarslan, Özden Anal, Özkan Karaman, Nevin Uzuner
Işık S, Çağlayan-Sözmen Ş, Asilsoy S, Kılıçarslan SK, Anal Ö, Karaman Ö, Uzuner N. Knowledge levels related to allergen specific immunotherapy and perspectives of parents whose children were diagnosed with asthma and/or allergic rhinitis in Turkey. Turk J Pediatr 2018; 60: 50-55. In the present study, we aimed to evaluate the knowledge levels and perspectives about allergen specific immunotherapy (ASI) of parents whose children were diagnosed with asthma and/or allergic rhinitis with positive skin prick test...
2018: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/30067481/life-threatening-event-risk-in-children-with-wolff-parkinson-white-syndrome-a-multicenter-international-study
#13
Susan P Etheridge, Carolina A Escudero, Andrew D Blaufox, Ian H Law, Brynn E Dechert-Crooks, Elizabeth A Stephenson, Anne M Dubin, Scott R Ceresnak, Kara S Motonaga, Jonathan R Skinner, Luciana D Marcondes, James C Perry, Kathryn K Collins, Stephen P Seslar, Michel Cabrera, Orhan Uzun, Bryan C Cannon, Peter F Aziz, Peter Kubuš, Ronn E Tanel, Santiago O Valdes, Sara Sami, Naomi J Kertesz, Jennifer Maldonado, Christopher Erickson, Jeremy P Moore, Hiroko Asakai, LuAnn Mill, Mark Abcede, Zebulon Z Spector, Shaji Menon, Mark Shwayder, David J Bradley, Mitchell I Cohen, Shubhayan Sanatani
OBJECTIVES: This study sought to characterize risk in children with Wolff-Parkinson-White (WPW) syndrome by comparing those who had experienced a life-threatening event (LTE) with a control population. BACKGROUND: Children with WPW syndrome are at risk of sudden death. METHODS: This retrospective multicenter pediatric study identified 912 subjects ≤21 years of age with WPW syndrome, using electrophysiology (EPS) studies. Case subjects had a history of LTE: sudden death, aborted sudden death, or atrial fibrillation (shortest pre-excited RR interval in atrial fibrillation [SPERRI] of ≤250 ms or with hemodynamic compromise); whereas subjects did not...
April 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/30036122/association-of-plasma-pentraxin-3-levels-with-retinopathy-and-systemic-factors-in-diabetic-patients
#14
Füsun Erdenen, Hülya Güngel, Esma Altunoğlu, Duygu Şak, Cüneyt Müderrisoğlu, Atakan Koro, Pınar Akça Güler, Muzaffer Ece Hakan Sahin, Gonul Simsek, Hafize Uzun
BACKGROUND: Diabetic retinopathy (DR) is mainly caused by metabolic factors, vascular inflammation, and endothelial dysfunction. We aimed to evaluate the relationship of DR with inflammatory and biochemical alterations in type 2 diabetics. METHODS: A total of 89 diabetic patients with retinopathy [(DR (+) (n = 30)], without retinopathy [(DR (-) (n = 32)], and 27 control subjects were involved in the study. Demographic properties, biochemical values, ophtalmologic evaluation, C-reactive protein (CRP), and pentraxin-3 (PTX-3) levels were recorded...
September 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/30031877/induction-of-peroxisomal-changes-in-oligodendrocytes-treated-with-7-ketocholesterol-attenuation-by-%C3%AE-tocopherol
#15
Thomas Nury, Randa Sghaier, Amira Zarrouk, Franck Ménétrier, Tugba Uzun, Valerio Leoni, Claudio Caccia, Wiem Meddeb, Amira Namsi, Khouloud Sassi, Wafa Mihoubi, Jean-Marc Riedinger, Mustapha Cherkaoui-Malki, Thibault Moreau, Anne Vejux, Gérard Lizard
The involvement of organelles in cell death is well established especially for endoplasmic reticulum, lysosomes and mitochondria. However, the role of the peroxisome is not well known, though peroxisomal dysfunction favors a rupture of redox equilibrium. To study the role of peroxisomes in cell death, 158 N murine oligodendrocytes were treated with 7-ketocholesterol (7 KC: 25-50 μM, 24 h). The highest concentration is known to induce oxiapoptophagy (OXIdative stress + APOPTOsis + autoPHAGY), whereas the lowest concentration does not induce cell death...
October 2018: Biochimie
https://www.readbyqxmd.com/read/30025792/metabolomic-and-glycomic-findings-in-posttraumatic-stress-disorder
#16
REVIEW
Marcela Konjevod, Lucija Tudor, Dubravka Svob Strac, Gordana Nedic Erjavec, Coral Barbas, Neven Zarkovic, Matea Nikolac Perkovic, Suzana Uzun, Oliver Kozumplik, Gordan Lauc, Nela Pivac
Posttraumatic stress disorder (PTSD) is a stressor-related disorder that develops in a subset of individuals exposed to a traumatic experience. Factors associated with vulnerability to PTSD are still not fully understood. PTSD is frequently comorbid with various psychiatric and somatic disorders, moderate response to treatment and remission rates. The term "theranostics" combines diagnosis, prognosis, and therapy and offers targeted therapy based on specific analyses. Theranostics, combined with novel techniques and approaches called "omics", which integrate genomics, transcriptomic, proteomics and metabolomics, might improve knowledge about biological underpinning of PTSD, and offer novel therapeutic strategies...
January 10, 2019: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29972412/adropin-and-irisin-in-patients-with-cardiac-cachexia
#17
Ali Kemal Kalkan, Huseyin Altug Cakmak, Mehmet Erturk, Kübra Erol Kalkan, Fatih Uzun, Omer Tasbulak, Vesile Ornek Diker, Suleyman Aydin, Ahmet Celik
BACKGROUND: Cardiac cachexia is an important predictive factor of the reduction in survival of patients with heart failure with reduced ejection fraction. OBJECTIVES: The aims of the present study were to evaluate adropin and irisin levels in cachectic and non-cachectic subjects and the relationships between the levels of these proteins and clinical and laboratory parameters in patients with HFrEF. METHODS: The clinical records of patients who were admitted to the cardiology outpatient clinic for heart failure with reduced ejection fraction were screened...
July 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29961135/the-effect-of-the-systematic-birth-preparation-program-on-fear-of-vaginal-delivery-and-quality-of-life
#18
Mucize Eric Ozdemir, Isil Uzun Cilingir, Gulsah Ilhan, Elif Yildiz, Karolin Ohanoglu
PURPOSE: The aim of this study was to assess the impact of systematic birth preparation program on fear of vaginal delivery and quality of life (QoL) in pregnant women who request elective cesarean delivery without any obstetric indication. METHODS: This study was conducted prospectively. A total of 100 women who requested elective cesarean delivery due to psychosocial reasons were included into the study. Women were divided into two groups according to their desire to participate in the systematic birth preparation program...
September 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29914237/the-effects-of-preadministration-of-local-anesthetic-on-pulsed-radiofrequency
#19
Tülin Arıcı, Mustafa Kurçaloğlu, İdris Şevki Köken, Bora Uzuner, Can Eyigör, Meltem Uyar
Background/aim: Pulsed radiofrequency (PRF) has been reported to be a safe and reliable method for the management of a variety of chronic pain syndromes. It is not known whether the preadministration of local anesthetic increases the size of the electrical field. We revealed the effects of administering local anesthetic on PRF and investigated whether they were related to local anesthetic or fluid effects. Materials and methods: Group 1 (n = 18) received PRF to the suprascapular nerve with 1 mL of bupivacaine, group 2 (n = 20) received PRF with 1 mL of physiological saline solution, and group 3 (n = 18) received PRF only...
June 14, 2018: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29842839/effect-of-acellular-amniotic-membrane-matrix-patch-on-healing-of-cut-surface-after-sleeve-gastrectomy-in-rats
#20
Süleyman Orman, Sinan Yol, Hüseyin Uzun, Ayşe Bahar Ceyran, Fatma Eyüboğlu
BACKGROUND: The aim of this study was to evaluate the effect of acellular amniotic membrane matrix patch on healing cut surface after sleeve gastrectomy in rats. METHODS: Thirty male Wistar albino rats were divided into three groups: control (n = 10), Experiment-1 (n = 10), and Experiment-2 (n = 10) groups. Control group rats underwent only sleeve gastrectomy with primary gastrorrhaphy. Experiment-1 group rats underwent sleeve gastrectomy, primary gastrorrhaphy and covered with acellular amniotic membrane matrix patch...
May 29, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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