Masae Furukawa, Hirobumi Tada, Resmi Raju, Jingshu Wang, Haruna Yokoi, Mitsuyoshi Yamada, Yosuke Shikama, Takashi Saito, Takaomi C Saido, Kenji Matsushita
OBJECTIVES: Many patients with Alzheimer's disease experience behavioral and psychological symptoms of dementia (BPSD), which significantly affect their quality of life. It is known that 5-Hydroxytryptamine (5-HT) plays a crucial role in the development of BPSD. However, the relationship between tooth loss and Alzheimer's disease symptoms, particularly aggression, has remained unexplored. Although nutritional status is known to influence the progression of dementia, the specific effect of tooth loss on peripheral symptoms, notably aggression, is not well understood...
March 21, 2024: Journal of Oral Biosciences