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Jason Pui Yin Cheung, Karen Yiu, Kenny Kwan, Kenneth M C Cheung
BACKGROUND: There is no agreement on frequency of distractions of magnetically controlled growing rods (MCGRs) but more frequent and smaller amounts of distractions mimic physiological spine growth. The mid- to long-term follow-up and management at skeletal maturity is unknown. OBJECTIVE: To analyze patients with mean 6 yr of follow-up and describe the fate of MCGR graduates. METHODS: Early onset scoliosis (EOS) patients treated with MCGRs with minimum 4 yr of follow-up and/or at graduation were studied...
August 9, 2018: Neurosurgery
Aislinn Joan Campbell MacPhail, Ivan Pui-Hung Au, Mavis Chan, Dominic Ngo-Tung Mak, Winko Wenkang An, Zoe Yau-Shan Chan, Janet Hanwen Zhang, Kenny Wong, Ann So, Nora Chan, Chris Kwok, Patrick Lau, David Draper, Roy Tsz-Hei Cheung
This study examined the effects of KT tape (KT) applied in an inhibitory manner on muscle activity, measured maximal grip strength, and perceived maximal grip strength in regular KT-users and non-users. This study was a single-blinded crossover study with sixty participants including 27 kT-users and 33 non-users. Participants underwent maximal grip strength tests with and without inhibitory KT applied across the wrist extensors. Muscle activity and maximal grip strength were measured, while perceived maximal grip strength was rated using a visual analogue scale...
July 2018: Journal of Bodywork and Movement Therapies
Mingyue Li, Grace Gar-Lee Yue, Stephen Kwok-Wing Tsui, Kwok-Pui Fung, Clara Bik-San Lau
BACKGROUND: Curcumin, a well-studied component in turmeric, exhibits potent antitumor effects in colorectal cancer. Previous studies showed that turmerones raised the accumulation of curcumin inside colonic cells, and curcumin present in turmeric ethanolic extract had enhanced anti-tumor activities in mice. Metastasis accounts for more than 90% colorectal cancer deaths. However, the anti-metastatic effect of turmeric extract on colorectal cancer is still unknown. METHODS: In the present study, colony formation, scratch, transwell and Western blot were used to assess colony formation, motility, migration and underlying mechanisms in vitro, respectively...
July 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Hicran Dönmez Özkan, Kubilay Metin, Zehra Burcu Bakir, Senem Yiğit Özer
OBJECTIVE: This study aimed to compare the debris removal efficacies of irrigation activation techniques using ex vivo biomolecular film. MATERIALS AND METHODS: Root canals of 50 human mandibular premolars were prepared, and freshly prepared collagen solutions were applied into the root canals using a peristaltic pump. Specimens were randomly divided into the five groups and irrigated with 3 mL of 5.25% sodium hypochlorite (NaOCl): G1 (needle irrigation and control group): a 27-gauge notched-tip irrigation needle (Endo-Eze; Ultradent, South Jordan, UT); G2, Vibringe sonic irrigation system (VSS) (Vibringe B...
August 10, 2018: Photomedicine and Laser Surgery
Li Lian Foo, Ina Ismiarti Shariffuddin, Sook Hui Chaw, Pui Kuan Lee, Chong En Lee, Yi Shang Chen, Lucy Chan
BACKGROUND: The Baska FESS mask is a new supraglottic airway designed for head and neck procedures. This prospective, randomized controlled trial compared the oropharyngeal leak pressure (OLP) of the Baska FESS mask with the LMA Supreme in different head and neck positions. METHODS: One hundred patients undergoing elective surgery were recruited. OLP was compared in supine position, 45° lateral rotation, 45° neck extension and 30° neck flexion. Glottic view, insertion time, ease of insertion, number of attempts, ease and time of insertion of gastric tube, and complications were also compared...
August 10, 2018: Expert Review of Medical Devices
Hsuan-Chen Wang, Ming-I Hsieh, Pui-Ching Choi, Chi-Jung Wu
This study compared the YeastOne and reference CLSI M38-A2 broth microdilution methods for antifungal susceptibility testing of Aspergillus species. The minimum inhibitory concentrations (MICs) of antifungal agents were determined for 100 Aspergillus isolates, including 54 A. fumigatus (24 TR34 /L98H isolates), 23 A. flavus , 13 A. terreus , and 10 A. niger isolates. The overall agreement (within two two-fold dilutions) between the two methods was 100%, 95%, 92%, and 90% for voriconazole, posaconazole, itraconazole, and amphotericin B, respectively...
August 9, 2018: Journal of Clinical Microbiology
Chiu Wai Shirley Chan, Helen Hoi Lun Tsang, Philip Hei Li, Kam Ho Lee, Chak Sing Lau, Pui Yan Stella Wong, Ho Yin Chung
OBJECTIVE: To compare the utility of Diffusion weighted imaging (DWI) with short tau inversion recovery (STIR) sequence in the diagnosis of early axial spondyloarthritis (SpA). METHODS: Three hundred and five patients with chronic back pain were recruited consecutively from 3 rheumatology centers. Clinical, radiological and blood parameters were recorded. Patients with back pain duration no more than 3 years were classified as having early disease. STIR sequence and DWI of the sacroiliac joints were obtained and assessed using the Spondyloarthritis Research Consortium of Canada (SPARCC) method...
2018: PloS One
Bruno Marques da Silva, Fabrício Scaini, Flávia Sens Fagundes Tomazinho, Carla Castiglia Gonzaga, Marilisa Carneiro Leão Gabardo, Flares Baratto-Filho
Introduction: The aim of this study was to compare root preparation of deciduous teeth with WaveOne Large (WO) and ProTaper F4 (PT) instruments with or without passive ultrasonic irrigation (PUI). Methods and Materials: Forty-eight deciduous teeth were scanned before and after root preparation and divided in four groups ( n =12): WO+EDTA (WO); WO+EDTA with PUI (WOPUI); PTF+EDTA (PT); and PT+EDTA with PUI (PTPUI). Root canal enlargement by micro-computed tomography and root canal cleaning by scanning electron microscopy (SEM) were analyzed...
2018: Iranian Endodontic Journal
Allison J Chen, Vicky Hwang, Pui Yee Law, Jay M Stewart, Daniel L Chao
PURPOSE: Diabetic retinopathy (DR) is the leading cause of preventable blindness in working-aged adults, and compliance in ophthalmic follow-up appointments is critical to prevent vision loss. However, barriers to follow-up care have not been well studied, especially in socio-economically disadvantaged groups. We investigated the risk factors for non-compliance to DR follow-up appointments in a safety-net county hospital. METHODS: Two hundred and nine patients who were treated for DR at the Zuckerberg San Francisco General Hospital retina clinic between 1 July 2015 and 30 January 2016 were enrolled in the study...
August 6, 2018: Ophthalmic Epidemiology
Cosy Wing Ching Cheung, Alice Wong Wai Yee, Pui Shan Chan, Sotirios H Saravelos, Jacqueline Pui Wah Chung, Lai Ping Cheung, Grace Wing Shan Kong, Tin-Chiu Li
RESEARCH QUESTION: Does music therapy help in reducing pain and anxiety in women undergoing transvaginal ultrasound-guided oocyte retrieval (TUGOR)? DESIGN: In this randomized controlled open label study, 209 participants were recruited and randomized into three groups (music group, n = 70; headphone group, n = 70; control group, n = 69). Patients' psychological status was assessed using the visual analogue scale of pain (VAS-P), satisfaction of pain control, state-trait anxiety inventory (STAI), Beck depression inventory (BDI), and general health questionnaire (GHQ)...
August 2018: Reproductive Biomedicine Online
Pui San Saw, Lay Hong Chuah, Shaun Wen Huey Lee
Background Pharmacists as highly qualified professionals face ethical dilemmas and conflicts in their daily practice. These issues manifest themselves in the daily practice of pharmacists, which require pharmacists to have the competencies to manage these dilemmas but there is limited formal training in ethical decision making during undergraduate pharmacy education. Objective To describe the implementation and evaluation of a methodological approach to managing ethical dilemma workshop for community pharmacists in Malaysia...
August 4, 2018: International Journal of Clinical Pharmacy
Karen H Y Wong, Michal Levy-Sakin, Pui-Yan Kwok
The human reference genome is used extensively in modern biological research. However, a single consensus representation is inadequate to provide a universal reference structure because it is a haplotype among many in the human population. Using 10× Genomics (10×G) "Linked-Read" technology, we perform whole genome sequencing (WGS) and de novo assembly on 17 individuals across five populations. We identify 1842 breakpoint-resolved non-reference unique insertions (NUIs) that, in aggregate, add up to 2...
August 2, 2018: Nature Communications
Sybil Obuobi, Ying Wang, JasmeetSingh Khara, Andreas Riegger, Seah Ling Kuan, Pui Lai Rachel Ee
Protein-based polymeric polyelectrolytes are emerging as alternative synthetic nanoparticles owing to their biodegradability and biocompatibility. However, potential in vivo toxicity remains a significant challenge. Herein an array of protein polyelectrolytes generated from cationic human serum albumin (cHSA) and polyethylene glycol (PEG) are synthesized via synthetic customization as antimicrobials for the treatment of systemic infections. By varying PEG molecular weight and chain length, in vitro hemolytic activity can be fine-tuned without significantly affecting antimicrobial potency...
August 1, 2018: Macromolecular Bioscience
Marina Baechtold, Leonardo da Cunha, Erick Souza, Marilisa Gabardo, Kauhanna de Oliveira, Flares Baratto-Filho, Denise Leonardi
AIM: This study aimed to evaluate the fracture resistance of tooth crowns endodontically irrigated using different protocols. MATERIALS AND METHODS: A total of 76 bovine incisors were divided into four groups (n = 19): irrigation with distilled water (control; CON); conventional irrigation with positive apical pressure (PAP); passive ultrasonic irrigation using continuous flushing (PUI); and irrigation with PAP and heated sodium hypo-chlorite solution (PHS). The force required to fracture the crown was measured on a universal testing machine at an angle of 45°...
July 1, 2018: Journal of Contemporary Dental Practice
Qingjing Yang, Pui Ying Choy, Qingyang Zhao, Man Pan Leung, Hoi Shan Chan, Chau Ming So, Wing-Tak Wong, Fuk Yee Kwong
Palladium-catalyzed C-N bond coupling reaction between NH-sulfoximines and aryl halides (e.g. -Br, -I, -Cl and pseudohalides, -OTf, -ONf) has been successfully achieved. Nevertheless, aryl tosylates/mesylates left much to be succeeded. In this report, a general N-arylation of sulfoximines with aryl sulfonates is described. Using Pd(OAc)2/MeO-CM-phos complex, the N-aryl sulfoximine products can be obtained in good-to-excellent yields (up to 99%) with good common functional group compatibility. In addition to arene moieties, alkenyl tosylates are shown to be successful coupling partners...
July 31, 2018: Journal of Organic Chemistry
Haon-Yao Chen, Kok Kwang Ng, Chien-Hsien Lee, Tzu-Yang Chen, Pui-Kwan Andy Hong, Ping-Yi Yang, Cheng-Fang Lin
Anaerobic processes have been applied to treat low-strength domestic wastewaters with significant energy saving. However, anaerobic process effluents must be further removed of residual organics and total nitrogen before discharge. Reported here are an aerobic entrapped bio-technology (EBT) system and an EBT coupled with activated sludge (EBT + AS) system being tested as a post-anaerobic treatment. Both systems have been operated under aerobic condition to provide organics and total nitrogen removal, achieving COD removal by 74-88% and TN removal by 58-65% at hydraulic retention times of 8-24 h...
July 19, 2018: Bioresource Technology
Shengzhi Sun, Linwei Tian, Wangnan Cao, Poh-Chin Lai, Paulina Pui Yun Wong, Ruby Siu-Yin Lee, Tonya G Mason, Alexander Krämer, Chit-Ming Wong
BACKGROUND: City is becoming warmer, especially in the process of urbanization and climate change. However, it is largely unknown whether this warming urban climate may modify the short-term effects of air pollution. OBJECTIVES: To test whether warmer urban climates intensify the acute mortality effects of air pollution on pneumonia in Hong Kong. METHODS: Participants who died of pneumonia from a prospective Chinese elderly cohort between 1998 and 2011 were selected as cases...
July 23, 2018: Science of the Total Environment
Carmen L Wilson, Carrie R Howell, Robyn E Partin, Lu Lu, Sue C Kaste, Daniel A Mulrooney, Ching-Hon Pui, Jennifer Q Lanctot, Deo Kumar Srivastava, Leslie L Robison, Melissa M Hudson, Kirsten K Ness
INTRODUCTION: We aimed to determine the prevalence of self-reported adverse health status among childhood acute lymphoblastic leukemia (ALL) survivors and to identify associations between components of physical fitness and health status. METHODS: Participants included 365 ALL survivors (mean age at evaluation of 28.6 ± 5.9 years) and 365 age-, sex-, and race-matched community controls. Self-report of poor general health, poor mental health, functional impairments, and activity limitations were used to describe adverse health status...
July 29, 2018: Pediatric Blood & Cancer
Patrick Pui-Kin Kor, Rick Yiu Cho Kwan, Justina Yat-Wa Liu, Claudia Lai
PURPOSE: Use of physical restraints is common in nursing homes, although empirical evidence has shown it to be a hazardous measure. This article aims to understand whether there were any changes in nursing home staff's knowledge, attitudes, and practices of using physical restraints in Hong Kong, after years of deliberation on this topic. METHODS: A questionnaire about the knowledge, attitude, and practice of using physical restraint was sent to all 298 staff members in four nursing homes in Hong Kong run by a nongovernmental organization...
July 29, 2018: Journal of Nursing Scholarship
Jiří Moravec, Jiří Šmíd, Jan Štundl, Edgar Lehr
Cercosaurine lizards (subfamily Cercosaurinae of the family Gymnophthalmidae) represent a substantial component of the reptile fauna in the Neotropics. Several attempts have been made to reconstruct the phylogenetic relationships within this group, but most studies focused on particular genera or regions and did not cover the subfamily as a whole. In this study, material from the montane forests of Peru was newly sequenced. In combination with all cercosaurine sequences available on GenBank, an updated phylogeny of Cercosaurinae is provided...
2018: ZooKeys
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