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Eunice Lee, Bulaporn Natipagon-Shah, Samantha Sangsanoi-Terkchareon, Umme Shefa Warda, Shin-Young Lee
This study examined factors related to colorectal cancer (CRC) screening uptake among Thais in the United States. A total of 121 Thais between 50 and 75 years of age, who were married and living in southern California participated in the survey (mean age = 61 years). Out of all the participants, only 21% of the participants had fecal occult blood tests, 21% had sigmoidoscopy, and 45% had colonoscopy that were within the recommended period. Overall, 55% of participants met CRC screening adherence criteria...
October 19, 2018: Journal of Community Health
Stefan Quadlbauer, Ch Pezzei, J Jurkowitsch, R Rosenauer, A Pichler, S Schättin, T Hausner, M Leixnering
INTRODUCTION: Distal radius fractures (DRF) are the most common fractures of the upper extremities. The incidence is expected to continue rising in the next years due to the increased life expectancy. Palmar locking plate stabilizing has since become the standard treatment for dorsally displaced DRF with a complication rate of 8-39% reported in the literature. Main aim of this study was to investigate the incidence of complications after DRF stabilization using palmar angular stable locking plate...
October 19, 2018: Archives of Orthopaedic and Trauma Surgery
Pierpaolo Palumbo, Clemens Becker, Stefania Bandinelli, Lorenzo Chiari
BACKGROUND: The current guidelines for fall prevention in community-dwelling older adults issued by the American Geriatrics Society and British Geriatrics Society (AGS/BGS) indicate an algorithm for identifying who is at increased risk of falling. The predictive accuracy of this algorithm has never been assessed, nor have the consequences that its introduction in clinical practice would bring about. AIMS: To evaluate this risk screening algorithm, estimating its predictive accuracy and its potential impact...
October 19, 2018: Aging Clinical and Experimental Research
Björn Westerlind, Carl Johan Östgren, Sigvard Mölstad, Patrik Midlöv, Staffan Hägg
BACKGROUND: Falls and related injuries are common among older people, and several drug classes are considered to increase fall risk. AIMS: This study aimed to investigate the association between the use of certain drug classes and falls in older nursing home residents in Sweden, and relate these to different age groups. METHODS: Information on falls that occurred in the previous year and regular use of possible fall risk drugs including non-benzodiazepine hypnotics (zopiclone and zolpidem) was collected from 331 nursing home residents during 2008-2011...
October 19, 2018: Aging Clinical and Experimental Research
Daisuke Sato, Satoshi Ikeda, Seiji Koga, Yuki Yamagata, Masamichi Eguchi, Tsuyoshi Yonekura, Akira Tsuneto, Tsuyoshi Yoshimuta, Yuji Koide, Hiroaki Kawano, Koji Maemura
Venous thromboembolism (VTE) is a multifactorial disease. Cancer and older age are risk factors for both recurrent VTE and bleeding under anticoagulant therapy. Oral direct factor Xa inhibitors (Xa inhibitors) have been widely used to treat VTE. However, their effectiveness and safety in cancer and elderly patients have not been fully elucidated. A total of 187 consecutive patients who started Xa inhibitors for VTE therapy between September 2014 and September 2016 were recruited. Patients' demographics, changes in VTE amount, VTE recurrence, clinically relevant bleeding, and death until February 2017 were compared between 92 cancer and 95 non-cancer patients, and 57 elderly (≥ 75 years) and 130 non-elderly patients...
October 19, 2018: Heart and Vessels
Carina Fernandes, A R Gonçalves, R Pasion, F Ferreira-Santos, F Barbosa, I P Martins, J Marques-Teixeira
Aging is associated with changes in cognitive and affective functioning, which likely shape older adults' social cognition. As the neural and psychological mechanisms underlying age differences in social abilities remain poorly understood, the present study aims to extend the research in this field. To this purpose, younger (n = 30; Mage = 26.6), middle-aged (n = 30; Mage = 48.4), and older adults (n = 29; Mage = 64.5) performed a task designed to assess affective perspective-taking, during an EEG recording...
October 15, 2018: Cognitive, Affective & Behavioral Neuroscience
Jason Moran, Rodrigo Ramirez-Campillo, Urs Granacher
BACKGROUND: Jump training (JT) can be used to enhance the ability of skeletal muscle to exert maximal force in as short a time as possible. Despite its usefulness as a method of performance enhancement in athletes, only a small number of studies have investigated its effects on muscle power in older adults. OBJECTIVES: The aims of this meta-analysis were to measure the effect of JT on muscular power in older adults (≥ 50 years), and to establish appropriate programming guidelines for this population...
October 20, 2018: Sports Medicine
Wangmi Liu, Jiayan Wu
The present study used the Surveillance, Epidemiology and End Results (SEER) database to identify demographic and prognostic characteristics of lung cancer with bone metastases in the United States from 2010 to 2014. 30,364 patients with metastatic lung cancer to bones were identified in the SEER database. Their information on the basic characteristics and the histological signatures of the cancer was extracted and analyzed. Joinpoint analysis was used to test the trends in annual percentage change (APC) of the incidence...
October 19, 2018: Clinical & Experimental Metastasis
Kyeong A So, In Ho Lee, Tae Jin Kim, Ki Heon Lee
PURPOSE: To evaluate the risk factors associated with persistent high-risk human papillomavirus (HR HPV) infections in patients undergoing cervical excision for treatment of high-grade squamous intraepithelial lesion (HSIL). METHODS: A retrospective cohort study included 160 patients who underwent cervical excision for treatment of HSIL between January 2014 and December 2014. The clinical characteristics, cervical cytology, and HPV test results were reviewed. Persistent HR HPV infections were identified within 6 months after treatment...
October 19, 2018: Archives of Gynecology and Obstetrics
Xuexin He, Jiali Ji, Rongrong Dong, Hong Liu, Xiaolan Dai, Chongjian Wang, Francisco J Esteva, Sai-Ching Jim Yeung
BACKGROUND: Metaplastic breast cancer (MpBC) is a rare histological subtype of breast cancer recognized as a unique pathologic entity in 2000. However, the pathogenesis, optimal therapy, and prognosis of MpBC and the potential effect of systemic treatments on different subtypes of MpBC are not well defined. METHODS: A retrospective population-based study was performed to identify breast cancer patients with MpBC and other triple-negative breast cancers (TNBC) between 2010 and 2014 using the surveillance, Epidemiology, and End Results (SEER) database...
October 19, 2018: Breast Cancer Research and Treatment
Vladimír Remeš, Lenka Harmáčková
Climate is a major driver of species diversity. However, its effect can be either direct due to species physiological tolerances or indirect, whereby wetter climates facilitate more complex vegetation and consequently higher diversity due to greater resource availability. Yet, studies quantifying both direct and indirect effects of climate on multiple dimensions of diversity are rare. We used extensive data on species distributions, morphological and ecological traits, and vegetation across Australia to quantify both direct (water availability) and indirect (habitat diversity and canopy height) effects of climate on the species richness (SR), phylogenetic diversity (PD), and functional diversity (FD) of 536 species of birds...
October 19, 2018: Scientific Reports
Ryan D Nipp, Margaret Ruddy, Charn-Xin Fuh, Mark L Zangardi, Christine Chio, E Bridget Kim, Barbara Kong Mui Li, Ying Long, Gayle C Blouin, Daniel Lage, David P Ryan, Joseph A Greer, Areej El-Jawahri, Jennifer S Temel
BACKGROUND: Oncology clinicians often struggle with managing medications and vaccinations in older adults with cancer. We sought to demonstrate the feasibility and preliminary efficacy of integrating pharmacists into the care of older adults with cancer to enhance medication management and vaccination administration. METHODS: We randomly assigned patients aged ≥65 years with breast, gastrointestinal, or lung cancer receiving first-line chemotherapy to the pharmacy intervention or usual care...
October 19, 2018: Oncologist
Kate MacKrill, Keith J Petrie
OBJECTIVE: Following a switch from either a generic or branded antidepressant (venlafaxine) to a new generic, we investigated the factors associated with a preference for branded medicines, side effects reported following switching and efficacy ratings of the new generic drug. DESIGN: A cross-sectional survey of patients switched to a new generic. SETTING: Patients accessing venlafaxine information online from the New Zealand government pharmaceuticals funding website...
October 18, 2018: BMJ Open
Heloisa Maria Jácome Sousa Britto, Bruna Silva Oliveira, Cristiano Santos Gomes, Juliana Martins Pinto, Ricardo Oliveira Guerra
INTRODUCTION: Mobility decline compromises functionality and quality of life in old age. Life-Space Assessment (LSA) evaluates mobility considering interaction between person and environment. The International Classification of Functioning, Disability and Health (ICF) is a reference to identify and categorise the personal and environmental contextual factors associated to the LSA. Our objective is identifying contextual factors that may influence life-space mobility of older community-dwelling adults based on ICF...
October 18, 2018: BMJ Open
Alexis J Pillsbury, Catherine Glover, Peter Jacoby, Helen E Quinn, Parveen Fathima, Patrick Cashman, Alan Leeb, Christopher C Blyth, Michael S Gold, Thomas Snelling, Kristine K Macartney
OBJECTIVE: To actively solicit adverse events experienced in the days following immunisation with quadrivalent inactivated influenza vaccine using Australia's near real-time, participant-based vaccine safety surveillance system, AusVaxSafety. DESIGN AND SETTING: Observational cohort study conducted in 194 sentinel surveillance immunisation sites (primary care, hospital and community-based clinics) across Australia. PARTICIPANTS: Individuals aged ≥6 months who received a routine seasonal influenza vaccine at a participating site (n=102 911) and responded to a survey (via short message service or email) sent 3 days after vaccination about adverse events experienced (n=73 892; 71...
October 18, 2018: BMJ Open
Esther Williamson, Lesley Ward, Karan Vadher, Susan J Dutton, Ben Parker, Stavros Petrou, Charles E Hutchinson, Richard Gagen, Nigel K Arden, Karen Barker, Graham Boniface, Julie Bruce, Gary Collins, Jeremy Fairbank, Judith Fitch, David P French, Angela Garrett, Varsha Gandhi, Frances Griffiths, Zara Hansen, Christian Mallen, Alana Morris, Sarah E Lamb
INTRODUCTION: Neurogenic claudication due to spinal stenosis is common in older adults. The effectiveness of conservative interventions is not known. The aim of the study is to estimate the clinical and cost-effectiveness of a physiotherapist-delivered, combined physical and psychological intervention. METHODS AND ANALYSIS: This is a pragmatic, multicentred, randomised controlled trial. Participants are randomised to a combined physical and psychological intervention (Better Outcomes for Older people with Spinal Trouble (BOOST) programme) or best practice advice (control)...
October 18, 2018: BMJ Open
Tao Zhang, Rui Yan, Qifeng Chen, Xuhua Ying, Yujia Zhai, Fudong Li, Xinyi Wang, Fan He, Chiyu Ye, Junfen Lin
OBJECTIVES: To investigate the associations between body mass index (BMI), waist-to-hip ratio (WHR) and cognitive function among Chinese elderly. DESIGN: Cross-sectional study. SETTING: Community. PARTICIPANTS: Data were obtained from the baseline survey of a community-based cohort in Zhejiang Province, and 9326 persons aged 60 years and older were enrolled. PRIMARY OUTCOME MEASURES: We investigated the association between BMI and cognition, and then explored the association between WHR and cognition across different quartiles of BMI...
October 18, 2018: BMJ Open
Randi Stokke
BACKGROUND: Due to demographic changes with an aging population, there is a demand for technology innovations in care services. However, technology innovations have proven difficult to implement in regular use. To understand the complexity of technology innovations in care practices, we need a knowledge base of the complex and diverse experiences of people interacting with established technologies. OBJECTIVE: This paper addresses the research gap in relation to understanding the microcontext of co-production of care involving established technologies integrated into care practices...
October 19, 2018: Journal of Medical Internet Research
Denny Meyer, Madawa W Jayawardana, Samuel D Muir, David Yen-Teh Ho, Olivia Sackett
BACKGROUND: Workplace programs designed to improve the health and psychological well-being of employees are becoming increasingly popular. However, there are mixed reports regarding the effectiveness of such programs and little analysis of what helps people to engage with such programs. OBJECTIVE: This evaluation of a particularly broad, team-based, digital health and well-being program uses mixed methods to identify the elements of the program that reduce work stress and promote psychological well-being, sleep quality, and productivity of employees...
October 19, 2018: Journal of Medical Internet Research
Mohammed Yousufuddin, Nathan Young, Jessica Shultz, Taylor Doyle, Karen M Fuerstenberg, Kelsey Jensen, Kogulavadanan Arumaithurai, Mohammad H Murad
BACKGROUND: We examined predictors of recurrent hospitalizations and the importance of these hospitalizations for subsequent mortality after incident transient ischemic attacks (TIA) that have not yet been investigated. METHODS: Adults hospitalized for TIA from 2000 through 2017 were examined for recurrent hospitalizations, days, and percentage of time spent hospitalized and long-term mortality. RESULTS: Of 266 patients hospitalized for TIA, 122 died, 212 had 826 anycondition hospitalization (59 from TIA-related conditions) corresponding to 3384 inpatient days during 1693 person-years of follow-up...
October 16, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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