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https://www.readbyqxmd.com/read/30106681/denoising-sparse-autoencoder-based-ictal-eeg-classification
#1
Yang Qiu, Weidong Zhou, Nana Yu, Peidong Du
Automatic seizure detection technology can automatic mark the EEG by using epileptic detection algorithm, which is helpful to the diagnosis and treatment of epileptic diseases. This paper presents an EEG classification framework based on the denoising sparse autoencoder. The denoising sparse autoencoder (DSAE) is an improved unsupervised deep neural network over sparse autoencoder and denoising autoencoder, which can learn the closest representation of the data. The sparsity constraint applied in the hidden layer of the network makes the expression of data as sparse as possible so as to obtain more efficient representation of EEG signals...
August 8, 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/30102723/susceptibility-to-audio-signals-during-autonomous-driving
#2
Remo M A van der Heiden, Christian P Janssen, Stella F Donker, Lotte E S Hardeman, Keri Mans, J Leon Kenemans
We investigate how susceptible human drivers are to auditory signals in three situations: when stationary, when driving, or when being driven by an autonomous vehicle. Previous research has shown that human susceptibility is reduced when driving compared to when being stationary. However, it is not known how susceptible humans are under autonomous driving conditions. At the same time, good susceptibility is crucial under autonomous driving conditions, as such systems might use auditory signals to communicate a transition of control from the automated vehicle to the human driver...
2018: PloS One
https://www.readbyqxmd.com/read/30101242/single-molecule-tracking-in-live-yersinia-enterocolitica-reveals-distinct-cytosolic-complexes-of-injectisome-subunits
#3
Julian Michael Rocha, Charles Joseph Richardson, Mingxing Zhang, Caroline Maureen Darch, Eugene Cai, Andreas Diepold, Andreas Gahlmann
In bacterial type 3 secretion, substrate proteins are actively transported from the bacterial cytoplasm into the host cell cytoplasm by a large membrane-embedded machinery called the injectisome. Injectisomes transport secretion substrates in response to specific environmental signals, but the molecular details by which the cytosolic secretion substrates are selected and transported through the type 3 secretion pathway remain unclear. Secretion activity and substrate selectivity are thought to be controlled by a sorting platform consisting of the proteins SctK, SctQ, SctL, and SctN, which together localize to the cytoplasmic side of membrane-embedded injectisomes...
August 13, 2018: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/30093975/extracellular-atp-is-a-danger-signal-activating-p2x7-receptor-in-a-lps-mediated-inflammation-ards-ali
#4
Sanja Cicko, Thomas Christian Köhler, Cemil Korcan Ayata, Tobias Müller, Nicolas Ehrat, Anja Meyer, Madelon Hossfeld, Andreas Zech, Francesco Di Virgilio, Marco Idzko
Acute respiratory distress syndrome (ARDS) is a life-threating lung condition resulting from a direct and indirect injury to the lungs [1, 2]. Pathophysiologically it is characterized by an acute alveolar damage, an increased permeability of the microvascular-barrier, leading to protein-rich pulmonary edema and subsequent impairment of arterial oxygenation and respiratory failure [1]. This study examined the role of extracellular ATP in recruiting inflammatory cells to the lung after induction of acute lung injury with lipopolysaccharide (LPS)...
July 17, 2018: Oncotarget
https://www.readbyqxmd.com/read/30093226/quercetin-potentiates-the-concurrent-hyper-accumulation-of-cellular-biomass-and-lipids-in-chlorella-vulgaris
#5
REVIEW
Yuhan Ma, Srinivasan Balamurugan, Wasiqi Yuan, Fan Yang, Caiguo Tang, Hao Hu, Huilan Zhang, Xian Shu, Minghao Li, Shengwei Huang, Hongye Li, Lifang Wu
Provision of chemical modulators has emerged as an effective strategy to govern cell growth and development. Here, the impact of flavonoid quercetin on algal growth, lipid accumulation and transcriptional patterns was investigated in the green microalga Chlorella vulgaris. These results demonstrated that quercetin (15 μg/l) significantly enhanced the cellular biomass and photosynthetic efficiency, with up to 2.5-fold in the biomass in the stationary phase. Lipidomic analyses revealed that lipid content was increased by 1...
August 1, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/30074489/dual-electrode-motion-artifact-cancellation-for-mobile-electroencephalography
#6
Andrew D Nordin, W David Hairston, Daniel Perry Ferris
OBJECTIVE: Our purpose was to evaluate the ability of a dual electrode approach to remove motion artifact from electroencephalography (EEG) measurements. APPROACH: We used a phantom human head model and robotic motion platform to induce motion while collecting scalp EEG. We assembled a dual electrode array capturing a) artificial neural signals plus noise from scalp EEG electrodes, and b) electrically isolated motion artifact noise. We recorded artificial neural signals broadcast from antennae in the phantom head during continuous vertical sinusoidal movements (stationary, 1...
August 3, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/30066082/a-novel-signal-processing-approach-to-auditory-phantom-perception
#7
I-Hui Hsieh, Jia-Wei Liu
The ear and brain interact in an orchestrated manner to create sensations of phantom tones that are audible to listeners despite lacking physical presence in original sounds. The relative contribution of peripheral sensory cell activity and cortical mechanisms to phantom hearing remains elusive. The current study addressed the question of whether non-linear components of a complex signal exist that are not captured by the linear combination of cosines in a series. To this end, we investigated the source and spectro-temporal dynamics of non-linear components within two-tone complexes related to phantom acoustic perception...
July 31, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/30064359/inhibition-of-bacteriochlorophyll-biosynthesis-in-the-purple-phototrophic-bacteria-rhodospirillumrubrum-and-rhodobacter-capsulatus-grown-in-the-presence-of-a-toxic-concentration-of-selenite
#8
Janine Kessi, Stefan Hörtensteiner
Background In many works, the chemical composition of bacterially-produced elemental selenium nanoparticles (Se0 -nanoparticles) was investigated using electron dispersive X-ray analysis. The results suggest that these particles should be associated with organic compounds. However, a complete analysis of their chemical composition is still missing. Aiming at identifying organic compounds associated with the Se0 -nanoparticles produced by the purple phototrophic bacteria Rhodospirillum rubrum and Rhodobacter capsulatus (α group of the proteobacteria), we used MALDI-TOF spectrometry...
July 31, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/30063347/characterization-of-nine-isomers-in-commercial-samples-of-perfluoroethylcyclohexane-sulfonate-and-of-some-minor-components-including-pfos-isomers
#9
Tomislav Stefanac, Robert McCrindle, Alan McAlees, Nicole Riddell, Allison L Brazeau, Brock Chittim
Electrochemical fluorination of 4-ethylbenzenesulfonyl halides produces a mixture of compounds that has found extensive use as an erosion inhibitor in aircraft hydraulic fluids. This paper reports a study of the composition of commercial samples of this material from two industrial scale manufacturers in terms of the structures and relative concentrations of their components, the major of which is perfluoroethylcyclohexane sulfonate (PFECHS). Fractionation of one of these mixtures by column chromatography produced fractions in which all significant components were of sufficient purity to allow assignment of their structures by 19F NMR spectroscopy...
July 31, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/30061754/a-personalized-arrhythmia-monitoring-platform
#10
Sandeep Raj, Kailash Chandra Ray
Arrhythmia detection is the core of cardiovascular disease diagnosis. Though, there is no such generic solution for detecting the arrhythmias at the moment they occur which is due to the non-stationary nature and inter-patient variations of ECG signals. The feature extraction and classification techniques are significant tools widely used in the automated classification of arrhythmias. This study aims to develop a personalized arrhythmia monitoring platform allowing real-time detection of arrhythmias from the subject's electrocardiogram (ECG) signal for point-of-care usage...
July 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30051303/riggs-type-dominant-congenital-stationary-night-blindness-erg-findings-a-new-gnat1-mutation-and-a-systemic-association
#11
Michael F Marmor, Christina Zeitz
PURPOSE: Complete congenital stationary night blindness (CSNB) is most often x-linked or recessive, and associated with a transmission defect from photoreceptors to bipolar cells. This produces a characteristic "negative" Schubert-Bornschein type of scotopic rod-cone electroretinogram (ERG) with a large a-wave and minimal b-wave. CSNB from abnormalities in phototransduction can be recessive or dominant and is much less common. This produces a Riggs type of ERG with loss of the rod a-wave as well as the b-wave...
August 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/30041186/licos-a-new-linguistically-controlled-sentences-test-to-assess-functional-hearing-performance
#12
Martine Coene, Stefanie Krijger, Eline van Knijff, Matthias Meeuws, Geert De Ceulaer, Paul J Govaerts
PURPOSE: To overcome the potential tension between clinical and ecological validity in speech audiometric assessment by creating a new set of sentence materials with high linguistic validity for the Dutch-speaking area. METHODS: A linguistic "fingerprint" of modern spoken Dutch and Flemish served to generate a set of sentences recorded from 1 male and 1 female talker. The sentences were presented to 30 normal-hearing listeners in stationary speech noise at a signal-to-noise ratio (SNR) of -5 dB sound pressure level (SPL)...
July 24, 2018: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/30040820/interaction-of-lipoprotein-qseg-with-sensor-kinase-qsee-in-the-periplasm-controls-the-phosphorylation-state-of-the-two-component-system-qsee-qsef-in-escherichia-coli
#13
Yvonne Göpel, Boris Görke
Histidine kinase QseE and response regulator QseF compose a two-component system in Enterobacteriaceae. In Escherichia coli K-12 QseF activates transcription of glmY and of rpoE from Sigma 54-dependent promoters by binding to upstream activating sequences. Small RNA GlmY and RpoE (Sigma 24) are important regulators of cell envelope homeostasis. In pathogenic Enterobacteriaceae QseE/QseF are required for virulence. In enterohemorrhagic E. coli QseE was reported to sense the host hormone epinephrine and to regulate virulence genes post-transcriptionally through employment of GlmY...
July 2018: PLoS Genetics
https://www.readbyqxmd.com/read/30038023/gating-induced-large-aqueous-volumetric-remodeling-and-aspartate-tolerance-in-the-voltage-sensor-domain-of-shaker-k-channels
#14
Ignacio Díaz-Franulic, Vivian González-Pérez, Hans Moldenhauer, Nieves Navarro-Quezada, David Naranjo
Neurons encode electrical signals with critically tuned voltage-gated ion channels and enzymes. Dedicated voltage sensor domains (VSDs) in these membrane proteins activate coordinately with an unresolved structural change. Such change conveys the transmembrane translocation of four positively charged arginine side chains, the voltage-sensing residues (VSRs; R1-R4). Countercharges and lipid phosphohead groups likely stabilize these VSRs within the low-dielectric core of the protein. However, the role of hydration, a sign-independent charge stabilizer, remains unclear...
August 7, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/30037104/distributed-compressed-sensing-based-ground-moving-target-indication-for-dual-channel-sar-system
#15
Jing Liu, Xiaoqing Tian, Jiayuan Jiang, Kaiyu Huang
The dual-channel synthetic aperture radar (SAR) system is widely applied in the field of ground moving-target indication (GMTI). With the increase of the imaging resolution, the resulting substantial raw data samples increase the transmission and storage burden. We tackle the problem by adopting the joint sparsity model 1 (JSM-1) in distributed compressed sensing (DCS) to exploit the correlation between the two channels of the dual-channel SAR system. We propose a novel algorithm, namely the hierarchical variational Bayesian based distributed compressed sensing (HVB-DCS) algorithm for the JSM-1 model, which decouples the common component from the innovation components by applying variational Bayesian approximation...
July 21, 2018: Sensors
https://www.readbyqxmd.com/read/30030121/agmatine-modulates-calcium-handling-in-cardiomyocytes-of-hibernating-ground-squirrels-through-calcium-sensing-receptor-signaling
#16
Alexander V Maltsev
True hibernators are remarkable group of mammals whose hearts are resistant to such stressors as deep hypothermia, ischemia, arrhythmia. Capability of cardiac cells from hibernating species to effectively rule Ca2+ homeostasis during torpor is poorly studied. Better understanding of these mechanisms could allow to introduce new strategies for improvement the cardiac performance and may be useful for cardiovascular medicine. Here for the first time we have shown that the regulation of Ca2+ handling and thereby cardiomyocyte contractility by endogenous neurotransmitter agmatine occurs through the modulation of calcium-sensing receptor (CaSR)...
July 17, 2018: Cellular Signalling
https://www.readbyqxmd.com/read/30027897/cardiotocography-and-beyond-a-review-of-one-dimensional-doppler-ultrasound-application-in-fetal-monitoring
#17
Faezeh Marzbanrad, Lisa Stroux, Gari D Clifford
One-dimensional Doppler ultrasound (1D-DUS) provides a low-cost and simple method for acquiring a rich signal for use in cardiovascular screening. However,
 despite the use of 1D-DUS in cardiotocography (CTG) for decades, there are still challenges that limit the effectiveness of its users in reducing fetal and neonatal morbidities and mortalities. This is partly due to the noisy, transient, complex and non-stationary nature of the 1D-DUS signals. Current challenges also include lack of efficient signal quality metrics, insufficient signal processing techniques for extraction of fetal heart rate and other vital parameters with adequate temporal resolution, and lack of appropriate clinical decision support for CTG and Doppler interpretation...
July 20, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/30025675/paradoxical-adaptation-of-successful-movements-the-crucial-role-of-internal-error-signals
#18
Valérie Gaveau, Anne-Emmanuelle Priot, Laure Pisella, Laurence Havé, Claude Prablanc, Yves Rossetti
Visuo-motor adaptation has been classically studied using movements aimed at visual targets with visual feedback. In this type of experimental design, the respective roles of the different error signals cannot be fully disentangled. Here, we show that visuo-motor adaptation occurs despite the terminal success of the action and the compensation of the external error by a jump of the visual target. By using three grasping task conditions we manipulated the retinal error signal between the seen hand and the target (external error) and the conflict between the hand's visual reafference and either the proprioceptive or the efference copy signal (internal error), in order to estimate their respective roles in prism adaptation...
July 16, 2018: Consciousness and Cognition
https://www.readbyqxmd.com/read/30025314/the-effects-of-algal-extracellular-substances-on-algal-growth-metabolism-and-long-term-medium-recycle-and-inhibition-alleviation-through-ultrasonication
#19
Ze Yu, Haiyan Pei, Qingjie Hou, Changliang Nie, Lijie Zhang, Zhigang Yang, Xiaodong Wang
The algal extracellular substances (AESs), mainly excreted in the lag and stationary phases, inhibited the algal growth and culture recycle. The AESs consisted of protein-like substances and saccharides, which restrained the algal lipid and protein biosynthesis. Moreover, the increasing reactive oxygen species and anti-oxidative enzymes caused by AESs led to the oxidative damage and suppressed the cell activity. The AESs affected the cells through two possible ways: one is the AESs adhered to the cell surfaces; another is the cells yielded signal molecules in response to the AESs...
July 7, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/30022730/speech-understanding-with-various-maskers-in-cochlear-implant-and-simulated-cochlear-implant-hearing-effects-of-spectral-resolution-and-implications-for-masking-release
#20
Naomi B H Croghan, Zachary M Smith
The purpose of this study was to investigate the relationship between psychophysical spectral resolution and sentence reception in various types of interfering backgrounds for listeners with cochlear implants and normal-hearing subjects listening to vocoded speech. Spectral resolution was measured with a spectral modulation detection (SMD) task. For speech testing, maskers included stationary speech-shaped noise (SSN), four-talker babble, multitone noise, and a competing talker. To explore the possible trade-offs between spectral resolution and susceptibility to different types of maskers, the degree of simulated current spread was varied within the vocoder group, achieving a range of performance for SMD and speech tasks...
January 2018: Trends in Hearing
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