keyword
https://read.qxmd.com/read/38143529/percutaneous-left-ventricular-assist-devices-in-refractory-cardiac-arrest-the-role-of-chest-compressions
#21
JOURNAL ARTICLE
Adam L Gottula, Brendan M McCracken, Takahiro Nakashima, Nicholas L Greer, Traci A Cramer, Nadia R Sutton, Kevin R Ward, Robert W Neumar, Mohamad Hakam Tiba, Cindy H Hsu
BACKGROUND: Recent studies describe an emerging role for percutaneous left ventricular assist devices such as Impella CP® as rescue therapy for refractory cardiac arrest. We hypothesized that the addition of mechanical chest compressions to percutaneous left ventricular assist device assisted CPR would improve hemodynamics by compressing the right ventricle and augmenting pulmonary blood flow and left ventricular filling. We performed a pilot study to test this hypothesis using a swine model of prolonged cardiac arrest...
December 2023: Resuscitation plus
https://read.qxmd.com/read/38141864/breathing-on-the-mind-treating-dyspnea-and-anxiety-symptoms-with-biofeedback-in-chronic-lung-disease-a-qualitative-analysis
#22
JOURNAL ARTICLE
Anna Norweg, Brittany Hofferber, Sophia Maguire, Cheongeun Oh, Victoria H Raveis, Naomi M Simon
RATIONALE: Chronic obstructive pulmonary disease (COPD) is characterized by dysfunctional breathing patterns that contribute to impaired lung function and symptoms of dyspnea, anxiety, and abnormal carbon dioxide (CO2 ) levels. OBJECTIVE: The study objective was to measure the acceptability of a new mind-body intervention we developed called Capnography-Assisted, Learned Monitored (CALM) Breathing, implemented before pulmonary rehabilitation. METHODS: CALM Breathing is a 4-week (8-session) intervention designed to treat dyspnea and anxiety in adults with COPD by targeting dysfunctional breathing behaviors (guided by end-tidal CO2 levels)...
December 21, 2023: Respiratory Medicine
https://read.qxmd.com/read/38133873/relationship-between-etco-2-and-paco-2-under-changing-capnogram-in-ventilated-infants-with-nava-an-observational-study
#23
JOURNAL ARTICLE
Daijiro Takahashi, Koko Goto, Kei Goto
This observational study evaluated the validity of end-tidal CO2 (ETCO2 ) as a surrogate for arterial PCO2 (PaCO2 ) in infants on neurally adjusted ventilatory assist (NAVA), particularly considering the influence of variable spontaneous breathing on capnography waveforms. The study involved 16 infants, analyzing 50 paired ETCO2 and PaCO2 values. Deming regression analysis highlighted a notably stronger correlation for maximum ETCO2 (r2  = 0.6783, p <0.0001) compared to mean ETCO2 (r2  = 0...
December 22, 2023: Indian Journal of Pediatrics
https://read.qxmd.com/read/38126093/peripheral-hypercapnic-chemosensitivity-at-rest-and-progressive-exercise-intensities-in-males-and-females
#24
JOURNAL ARTICLE
Madeline D Wright, Leah M Mann, Connor J Doherty, Benjamin P Thompson, Sarah A Angus, Jou-Chung Chang, Paolo B Dominelli
Peripheral hypercapnic chemosensitivity (PHC) is the ventilatory response to hypercapnia and is enhanced with acute whole-body exercise. However, little is known about the mechanism(s) responsible for the exercise related increase in PHC and if progressive exercise leads to further augmentation. We hypothesized that unloaded cycle exercise (0W) would increase PHC but progressively increasing the intensity would not further augment the response. Twenty healthy subjects completed 2 testing days. Day 1 was a maximal exercise test on a cycle ergometer to determine peak power output (Wmax )...
December 21, 2023: Journal of Applied Physiology
https://read.qxmd.com/read/38116893/impaired-cerebrovascular-co-2-reactivity-at-high-altitude-in-prematurely-born-adults
#25
JOURNAL ARTICLE
Giorgio Manferdelli, Benjamin J Narang, Nicolas Bourdillon, Guido Giardini, Tadej Debevec, Grégoire P Millet
Premature birth impairs cardiac and ventilatory responses to both hypoxia and hypercapnia, but little is known about cerebrovascular responses. Both at sea level and after 2 days at high altitude (3375 m), 16 young preterm-born (gestational age, 29 ± 1 weeks) and 15 age-matched term-born (40 ± 0 weeks) adults were exposed to two consecutive 4 min bouts of hyperoxic hypercapnic conditions (3% CO2 -97% O2 ; 6% CO2 -94% O2 ), followed by two periods of voluntary hyperventilation-induced hypocapnia...
December 20, 2023: Journal of Physiology
https://read.qxmd.com/read/38105354/elevation-of-end-tidal-co-2-during-exercise-is-attenuated-in-patients-with-cardiac-amyloidosis
#26
JOURNAL ARTICLE
Atsushi Shibata, Yasuhiro Izumiya, Toshitake Yoshida, Akiko Tanihata, Yumi Yamaguchi, Ryoko Kitada, Daiju Fukuda
Reduced exercise tolerance is one of the hallmarks of patients with cardiac amyloidosis (CA), but detailed biological responses during exercise were not investigated. The purpose of this study was to compare the cardiopulmonary exercise test (CPX) parameters between CA patients and propensity-matched heart failure patients. This was a single-center, retrospective, observational study of patients diagnosed with CA. The control group was extracted by propensity score matching from patients who underwent CPX for chronic heart failure during the same period...
December 18, 2023: Heart and Vessels
https://read.qxmd.com/read/38096770/end-tidal-carbon-dioxide-after-sodium-bicarbonate-infusion-during-mechanical-ventilation-or-ongoing-cardiopulmonary-resuscitation
#27
JOURNAL ARTICLE
Young-Il Roh, Hyung Il Kim, Sun Ju Kim, Kyoung-Chul Cha, Woo Jin Jung, Yeon Jae Park, Sung Oh Hwang
PURPOSE: End-tidal CO2 is used to monitor the ventilation status or hemodynamic efficacy during mechanical ventilation or cardiopulmonary resuscitation (CPR), and it may be affected by various factors including sodium bicarbonate administration. This study investigated changes in end-tidal CO2 after sodium bicarbonate administration. MATERIALS AND METHODS: This single-center, prospective observational study included adult patients who received sodium bicarbonate during mechanical ventilation or CPR...
February 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38091590/full-face-snorkel-masks-increase-the-incidence-of-hypoxaemia-and-hypercapnia-during-simulated-snorkelling-compared-to-conventional-snorkels
#28
JOURNAL ARTICLE
Janneke Grundemann, Xavier Ce Vrijdag, Nicole Ye Wong, Nicholas Gant, Simon J Mitchell, Hanna van Waart
INTRODUCTION: Air flow in full-face snorkel masks (FFSMs) should be unidirectional to prevent rebreathing of exhaled air. This study evaluated rebreathing and its consequences when using FFSMs compared to a conventional snorkel. METHODS: In a dry environment 20 participants wore three types of snorkel equipment in random order: Subea Easybreath FFSM; QingSong 180-degree panoramic FFSM; and a Beuchat Spy conventional snorkel (with nose clip), in three conditions: rest in a chair; light; and moderate intensity exercise on a cycle ergometer...
December 20, 2023: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://read.qxmd.com/read/38088784/in-vitro-model-of-prepacked-carbon-dioxide-absorber-use-development-and-testing
#29
JOURNAL ARTICLE
Jennifer Jouwena, Delphine Verbeke, Andre M De Wolf, Arne Neyrinck, Jan F A Hendrickx
BACKGROUND: CO2 absorbers allow the use of fresh gas flows (FGF) below minute ventilation (V̇E). Models are developed and tested in vitro to quantify their performance with variable CO2 load (V̇CO2), FGF, V̇E, end-tidal CO2 fraction (FETCO2), and the type of workstation used. METHODS: First principles are used to derive a linear relationship between FGF and fractional canister usage or FCU0.5 (the reciprocal of the time for the inspiratory CO2 fraction (FICO2) to reach 0...
December 13, 2023: Anesthesiology
https://read.qxmd.com/read/38088765/early-cardiac-arrest-hemodynamics-end-tidal-co2-and-outcome-in-pediatric-extracorporeal-cardiopulmonary-resuscitation-secondary-analysis-of-the-icu-resuscitation-project-dataset-2016-2021
#30
JOURNAL ARTICLE
Andrew R Yates, Maryam Y Naim, Ron W Reeder, Tageldin Ahmed, Russell K Banks, Michael J Bell, Robert A Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A Carcillo, Todd C Carpenter, J Michael Dean, J Wesley Diddle, Myke Federman, Richard Fernandez, Ericka L Fink, Deborah Franzon, Aisha H Frazier, Stuart H Friess, Kathryn Graham, Mark Hall, David A Hehir, Christopher M Horvat, Leanna L Huard, Tensing Maa, Arushi Manga, Patrick S McQuillen, Ryan W Morgan, Peter M Mourani, Vinay M Nadkarni, Daniel Notterman, Murray M Pollack, Anil Sapru, Carleen Schneiter, Matthew P Sharron, Neeraj Srivastava, Bradley Tilford, Shirley Viteri, David Wessel, Heather A Wolfe, Justin Yeh, Athena F Zuppa, Robert M Sutton, Kathleen L Meert
OBJECTIVES: Cannulation for extracorporeal membrane oxygenation during active extracorporeal cardiopulmonary resuscitation (ECPR) is a method to rescue patients refractory to standard resuscitation. We hypothesized that early arrest hemodynamics and end-tidal Co2 (ETco2) are associated with survival to hospital discharge with favorable neurologic outcome in pediatric ECPR patients. DESIGN: Preplanned, secondary analysis of pediatric Utstein, hemodynamic, and ventilatory data in ECPR patients collected during the 2016-2021 Improving Outcomes from Pediatric Cardiac Arrest study; the ICU-RESUScitation Project (ICU-RESUS; NCT02837497)...
December 13, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38070839/assessing-cerebrovascular-reactivity-cvr-in-rhesus-macaques-macaca-mulatta-using-a-hypercapnic-challenge-and-pseudo-continuous-arterial-spin-labeling-pcasl
#31
JOURNAL ARTICLE
Brendan J Johnson, Megan E Lipford, Richard A Barcus, John D Olson, George W Schaaf, Rachel N Andrews, Jeongchul Kim, Greg O Dugan, Simon Deycmar, Colin A Reed, Christopher T Whitlow, J Mark Cline
Cerebrovascular reactivity (CVR) is a measure of cerebral small vessels' ability to respond to changes in metabolic demand and can be quantified using magnetic resonance imaging (MRI) coupled with a vasoactive stimulus. Reduced CVR occurs with neurodegeneration and is associated with cognitive decline. While commonly measured in humans, few studies have evaluated CVR in animal models. Herein, we describe methods to induce hypercapnia in rhesus macaques (Macaca mulatta) under gas anesthesia to measure cerebral blood flow (CBF) and CVR using pseudo-continuous arterial spin labeling (pCASL)...
December 7, 2023: NeuroImage
https://read.qxmd.com/read/38065762/airway-management-in-neonates-and-infants-european-society-of-anaesthesiology-and-intensive-care-and-british-journal-of-anaesthesia-joint-guidelines
#32
JOURNAL ARTICLE
Nicola Disma, Takashi Asai, Evelien Cools, Alexandria Cronin, Thomas Engelhardt, John Fiadjoe, Alexander Fuchs, Annery Garcia-Marcinkiewicz, Walid Habre, Chloe Heath, Mathias Johansen, Jost Kaufmann, Maren Kleine-Brueggeney, Pete G Kovatsis, Peter Kranke, Andrea C Lusardi, Clyde Matava, James Peyton, Thomas Riva, Carolina S Romero, Britta von Ungern-Sternberg, Francis Veyckemans, Arash Afshari
Airway management is required during general anaesthesia and is essential for life-threatening conditions such as cardiopulmonary resuscitation. Evidence from recent trials indicates a high incidence of critical events during airway management, especially in neonates or infants. It is important to define the optimal techniques and strategies for airway management in these groups. In this joint European Society of Anaesthesiology and Intensive Care (ESAIC) and British Journal of Anaesthesia (BJA) guideline on airway management in neonates and infants, we present aggregated and evidence-based recommendations to assist clinicians in providing safe and effective medical care...
January 2024: British Journal of Anaesthesia
https://read.qxmd.com/read/38028725/microendoscopic-ultrasound-guided-percutaneous-tracheostomy-mugpt-a-case-series-describing-a-novel-technique-for-performing-percutaneous-tracheostomy
#33
Mayyas M Msheik, Amro F Khalili, Mustapha A Nahle, Chakib M Ayoub, Yara M Al Ghabour, Hachem Y Abdul-Kader, Marwan S Rizk
A percutaneous tracheostomy is a common surgical procedure done in intensive care. Several different techniques have been described. Recently, the addition of bronchoscopy or ultrasound has been advocated to decrease the risks and complications associated with the procedure; however, both aids used alone, bronchoscopy or ultrasound, have some drawbacks and pitfalls. In this manuscript, we describe a new technique implementing a new technology, Microendoscopy coupled with ultrasound to perform percutaneous dilation tracheostomy MUGPT...
2023: Case Reports in Critical Care
https://read.qxmd.com/read/38026213/an-ultra-small-integrated-co-2-infrared-gas-sensor-for-wearable-end-tidal-co-2-monitoring
#34
JOURNAL ARTICLE
Liyang Feng, Yanxiang Liu, Yi Wang, Hong Zhou, Ming Wu, Tie Li
Human physiological metabolic status can be obtained by monitoring exhaled CO2 concentration, but current CO2 sensors have disadvantages such as large size, high power consumption, and slow response time, which limit their application in wearable devices and portable instruments. In this article, we report a small size, good performance, and large range CO2 infrared gas sensor that integrates a high emissivity MEMS emitter chip, a high detectivity thermopile chip, and a high coupling efficiency optical chamber to achieve high efficiency optical-thermal-electrical conversion...
November 17, 2023: IScience
https://read.qxmd.com/read/38020590/lowered-oxidative-capacity-in-spinal-muscular-atrophy-jokela-type-comparison-with-mitochondrial-muscle-disease
#35
JOURNAL ARTICLE
Nadja Ratia, Edouard Palu, Hanna Lantto, Emil Ylikallio, Ritva Luukkonen, Anu Suomalainen, Mari Auranen, Päivi Piirilä
INTRODUCTION: Spinal muscular atrophy, Jokela type (SMAJ) is a rare autosomal dominantly hereditary form of spinal muscular atrophy caused by a point mutation c.197G>T in CHCHD10 . CHCHD10 is known to be involved in the regulation of mitochondrial function even though patients with SMAJ do not present with multiorgan symptoms of mitochondrial disease. We aimed to characterize the cardiopulmonary oxidative capacity of subjects with SMAJ compared to healthy controls and patients with mitochondrial myopathy...
2023: Frontiers in Neurology
https://read.qxmd.com/read/38018248/airway-management-in-neonates-and-infants-european-society-of-anaesthesiology-and-intensive-care-and-british-journal-of-anaesthesia-joint-guidelines
#36
JOURNAL ARTICLE
Nicola Disma, Takashi Asai, Evelien Cools, Alexandria Cronin, Thomas Engelhardt, John Fiadjoe, Alexander Fuchs, Annery Garcia-Marcinkiewicz, Walid Habre, Chloe Heath, Mathias Johansen, Jost Kaufmann, Maren Kleine-Brueggeney, Pete G Kovatsis, Peter Kranke, Andrea C Lusardi, Clyde Matava, James Peyton, Thomas Riva, Carolina S Romero, Britta von Ungern-Sternberg, Francis Veyckemans, Arash Afshari
Airway management is required during general anaesthesia and is essential for life-threatening conditions such as cardiopulmonary resuscitation. Evidence from recent trials indicates a high incidence of critical events during airway management, especially in neonates or infants. It is important to define the optimal techniques and strategies for airway management in these groups. In this joint European Society of Anaesthesiology and Intensive Care (ESAIC) and British Journal of Anaesthesia (BJA) guideline on airway management in neonates and infants, we present aggregated and evidence-based recommendations to assist clinicians in providing safe and effective medical care...
January 1, 2024: European Journal of Anaesthesiology
https://read.qxmd.com/read/37996828/evaluation-the-quality-of-bag-mask-ventilation-by-e-c-t-e-and-hook-technique-a-new-proposed-technique
#37
RANDOMIZED CONTROLLED TRIAL
Moloud Balafar, Mahboub Pouraghaei, Seyed Pouya Paknezhad, Saba Nemati Ahmad Abad, Hassan Soleimanpour
BACKGROUND: Bag-Mask Ventilation (BMV) is a crucial skill in managing emergency airway situations and induction of general anesthesia. Ensuring proficient BMV execution is imperative for healthcare providers. Various techniques exist for performing BMV. This study aims to compare the quality of ventilation achieved using the E/C technique, Thenar Eminence (T/E) technique and a novel approach referred to as the hook technique. The goal is to identify the most effective single-person BMV method...
November 23, 2023: BMC Anesthesiology
https://read.qxmd.com/read/37986138/pressure-controlled-ventilation-volume-guaranteed-mode-improves-bronchial-mucus-transport-velocity-in-patients-during-laparoscopic-surgery-for-gynecological-oncology-a-randomized-controlled-study
#38
RANDOMIZED CONTROLLED TRIAL
Chao Deng, Tao Xu, Xue-Kai Wang, Deng-Feng Gu
BACKGROUND: Mechanical ventilation during general anesthesia may impair airway mucosal function. This study aimed to investigate the effect of pressure-controlled ventilation-volume guaranteed (PCV-VG) on bronchial mucus transport velocity (BTV) in patients during laparoscopic surgery for gynecological oncology compared with volume controlled ventilation (VCV). METHODS: 66 patients undergoing elective a laparoscopic surgery for gynecological oncology. The patients were randomized into two group receiving either PCV-VG or VCV...
November 20, 2023: BMC Anesthesiology
https://read.qxmd.com/read/37969086/exposure-to-passive-heat-and-cold-stress-differentially-modulates-cerebrovascular-co-2-responsiveness
#39
JOURNAL ARTICLE
Bethany D Skinner, Rebekah A I Lucas, Samuel J E Lucas
Heat and cold stress influence cerebral blood flow (CBF) regulatory factors (e.g., arterial CO2 partial pressure). However, it is unclear whether the CBF response to a CO2 stimulus (i.e., cerebrovascular-CO2 responsiveness) is maintained under different thermal conditions. This study aimed to compare cerebrovascular-CO2 responsiveness between normothermia, passive heat and cold stress conditions. Sixteen participants (8 female; 25 ± 7 yrs) completed two experimental sessions (randomised) comprising of normothermic and either passive heat or cold stress conditions...
November 16, 2023: Journal of Applied Physiology
https://read.qxmd.com/read/37952392/improved-cerebrovascular-reactivity-mapping-using-coherence-weighted-general-linear-model-in-the-frequency-domain
#40
JOURNAL ARTICLE
Botian Xu, Chau Vu, Matthew Borzage, Clio González-Zacarías, Jian Shen, John Wood
Cerebrovascular reactivity (CVR) is a prognostic indicator of cerebrovascular health. Estimating CVR from endogenous end-tidal carbon dioxide (CO2 ) fluctuation and MRI signal recorded under resting state can be difficult due to the poor signal-to-noise ratio (SNR) of signals. Thus, we aimed to improve the method of estimating CVR from end-tidal CO2 and MRI signals. We proposed a coherence weighted general linear model (CW-GLM) to estimate CVR from the Fourier coefficients weighted by the signal coherence in frequency domain, which confers two advantages...
November 10, 2023: NeuroImage
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