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R Abdullaiev, G Oleynik, V Kremen, A Gryazin, E Timchenko
The problem of treating patients with loss of the skin and with a complicated course of the wound process remains topical. The problem is that, despite the relative technical simplicity of the dermatension method, the most significant complication is the decubitus of the stretchable flap, which is associated with a relatively high incidence of acute blood circulatory disturbances in the stretch tissues due to vascular compression with an excessive amount of injected fluid. The aim of the work is to improve the method of dermatension in reconstructive and recovery surgery of soft tissue defects of various genesis by planning and implementing dermatension at all its steps with instrumental control of the process using ultrasound and ICT in a complex...
October 2018: Georgian Medical News
Enisa Hodzic, Amira Drakovac, Edin Begic
Introduction: Heart rhythm disorders are quite common in the clinical course of acute myocardial infarction and have a significant influence on the prognosis of the disease. Aim: To investigate the type and frequency of ventricular arrhythmias in patients with acute myocardial infarction (AMI) by sex and age, according to localization of myocardial infarction, and correlated with troponin and C reactive protein (CRP). Material and Methods: A prospective, analytical, comparative clinical study was performed...
October 2018: Materia Socio-medica
Farzaneh Afkhaminia, Hasan Siamian, Naser Behnampour, Adib Moghimi, Shiva Karimpour
Background: One of the performance measures of any educational system is the degree to which students learn their education. Academic achievement includes the acquisition of a set of skills and abilities that are acquired during the course and in decision making and the various issues of leadership of individuals. A variety of factors affect the academic success of students. The present study aims to investigate the successful student's point of view from students of Mazandaran University of Medical Sciences in 2016-2017...
October 2018: Acta Informatica Medica: AIM
Anita Pokorny, Jaclyn Boyle, Alexander Hoffman, Cory P Coffey, Stacey Schneider
BACKGROUND AND PURPOSE: To describe and assess a longitudinal Professional Identity Development (PID) curriculum at Northeast Ohio Medical Universities (NEOMED) College of Pharmacy. EDUCATIONAL ACTIVITY AND SETTING: Northeast Ohio Medical University, a four-year professional program, has assimilated its career development and advising program into the curriculum as a primary element of the Pharmacist Patient Care Experience (PPCE) course. The concept of PID focuses on student pharmacist career development...
November 2018: Currents in Pharmacy Teaching & Learning
Natalie Hohmann, Jan Kavookjian
INTRODUCTION: Recent policies allow some pharmacists to prescribe hormonal birth control, which may improve access to hormonal contraceptives. This study explored associations between student pharmacists' hormonal contraception knowledge, attitudes, subjective norms, perceived behavioral control to counseling intentions, and preferred learning methods. METHODS: A cross-sectional online survey was developed to assess student pharmacists' hormonal contraception knowledge, perceptions, and counseling intentions...
November 2018: Currents in Pharmacy Teaching & Learning
Angelos G Kolias, Ellie Edlmann, Eric P Thelin, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A Anderson, Oliver Richards, Peter Whitfield, Monica Gherle, Karen Caldwell, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J Marcus, Aswin Chari, Paul Brennan, Antonio Belli, Simon Bond, Carole Turner, Lynne Whitehead, Ian Wilkinson, Peter J Hutchinson
BACKGROUND: Chronic subdural haematoma (CSDH) is a common neurosurgical condition, typically treated with surgical drainage of the haematoma. However, surgery is associated with mortality and morbidity, including up to 20% recurrence of the CSDH. Steroids, such as dexamethasone, have been identified as a potential therapy for reducing recurrence risk in surgically treated CSDHs. They have also been used as a conservative treatment option, thereby avoiding surgery altogether. The hypothesis of the Dex-CSDH trial is that a two-week course of dexamethasone in symptomatic patients with CSDH will lead to better functional outcome at six months...
December 4, 2018: Trials
Deb Rawlings, Lauren Miller-Lewis, Jennifer Tieman
Few previous studies have formally examined people's wishes regarding what they want to do before they die. This study aimed to describe responses to an activity within a Massive Open Online Course (MOOC) where people considered what was important when faced with their own mortality. We asked participants to complete the following: "Before I Die, I want to…". The content of participants' responses ( n = 633) was analysed qualitatively with a coding schema developed and then applied. All authors independently coded the first 100 "Before I Die" statements, followed by a second round of coding where themes were verified and confirmed...
November 30, 2018: Behavioral Sciences
S Volpe, B Alicja Jereczek-Fossa, D Zerini, D Patricia Rojas, C Fodor, A Vavassori, P Romanelli, S Vigorito, E Rondi, S Comi, R Cambria, F Cattani, S Dicuonzo, P De Marco, G Beltramo, G Musi, O De Cobelli, G Marvaso, R Orecchia
The aim is to present the technical feasibility and efficacy of multiple re-irradiation (re-EBRT) for local recurrence of prostate cancer (PCa) using retrospective analysis of an updated series of patients who received ablative re-EBRT with stereotactic image-guided technique for isolated local recurrence of PCa. Eight patients received three RT courses (2 re-RTs); of those 2 received 4 RT courses (3 re-RTs). Local relapse in the prostate was assessed by multiparametric magnetic resonance and/ or choline positron emission tomography...
November 25, 2018: Neoplasma
Maciej Pronicki, Dorota Piekutowska-Abramczuk, Dariusz Rokicki, Katarzyna Iwanicka-Pronicka, Wiesława Grajkowska
Mitochondrial DNA depletion consisting of the systemic reduction of mtDNA copy number in cells may have a heterogenous genetic basis, resulting from a pathogenic change in the nuclear genes involved in mtDNA synthesis. The mode of inheritance is autosomal recessive. Severe hepatocerebral disease represents one of many different clinical forms of so-called mitochondrial depletion syndrome (MDS). We present the liver histopathology of 13 children who eventually died in the course of hepatocerebral MDS confirmed molecularly, harbouring mutations of <i>DGUOK</i>, <i>MPV17</i>, and <i>POLG </i>genes...
2018: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
Takafumi Shima, Maiko Ozeki, Takashi Kinoshita, Kotaro Honda, Hitoshi Inoue, Shinsho Morita
RATIONALE: Nonocclusive mesenteric ischemia (NOMI) is a life-threatening disorder; prompt diagnosis is vital. Surgical treatment is often required, but some cases can be treated conservatively. We herein report an extremely rare case wherein protein-losing enteropathy (PLE) developed after conservative treatment of NOMI. PATIENT CONCERNS: The patient was a 66-year-old man. He underwent laparoscopic super low anterior resection and temporary ileostomy for sigmoid colon cancer and rectum cancer...
November 2018: Medicine (Baltimore)
Nancy A Warren, Harriette L Spiegel
Registered nurses are choosing to further their educational careers by seeking a bachelor's of science degree online (RN-to-BSN). The impetus for choosing the online delivery method is related to the ability to sign into a Learning Management System during times that are advantageous to their hospital work schedules, family, and daily living activities. The RN-to-BSN online option degree requires a Critical Care/Advanced Health Care Course as part of their curriculum plan; therefore, the article presents an overall view of the critical care course, the theoretical underpinnings for progression to the online delivery method, and examples of a module required by the critical care course...
January 2019: Critical Care Nursing Quarterly
Sushmita Pamidi, Sara J Meltzer, Natasha Garfield, Lorraine Lavigne, Allen Olha, Ahamed Khalyfa, Andrea Benedetti, Geneviève Tremblay, Robert Gagnon, Evelyne Rey, Kaberi Dasgupta, R John Kimoff
Background: Gestational diabetes (GDM) is associated with adverse short- and long-term maternal and fetal outcomes. Observational data support a link between sleep-disordered breathing (SDB) during pregnancy and GDM. However, it is unknown whether treatment of SDB with continuous positive airway pressure (CPAP) improves glucose control in this patient population. In addition, CPAP adherence and feasibility as a treatment option in pregnancy is unknown. This pilot randomized, controlled trial aims to primarily determine the feasibility of CPAP treatment in pregnant women with SDB and GDM...
2018: Frontiers in Endocrinology
Chandni N Patel, Michael D Swartz, Jeffrey S Tomasek, Laura E Vincent, Wallace E Hallum, John B Holcomb
BACKGROUND: Missing doses of antibiotics in hospitalized patients is a well-described but inadequately recognized issue. We hypothesized that missing doses of antibiotics decreases quality of care. METHODS: Retrospective study on patients admitted to the Shock Trauma ICU from February to June 2015. Patients prescribed a multidose course of antibiotics were evaluated. A missed antibiotic dose was one ordered but never given (a completely missed dose) or a dose that was not given within an hour before or after the planned time (an off-schedule missed dose)...
January 2019: Journal of Surgical Research
Christina Small, Grant Harmon, John Weaver, Vince Vivirito, Ramon Durazo-Arvizu, William Small, Matthew M Harkenrider
PURPOSE: Concurrent chemoradiotherapy and brachytherapy is the standard of care for locally advanced cervical cancer. Brachytherapy is an integral part of treatment and has improved overall survival. Research is needed to ascertain the planning modalities and schedules to best use resources and optimize treatment time course. We hypothesized that MRI-based brachytherapy when delivered with the described regimen would not prolong, and potentially shorten, overall treatment time as compared with CT-based brachytherapy...
November 26, 2018: Brachytherapy
Abdel Masieh Metry, Issa Al Salmi, Farida Al Balushi, Mohammed Abdalla Yousef, Faisal Al Ismaili, Alan Hola, Suad Hannawi
Systemic lupus erythematosus (SLE) is an autoimmune multisystem inflammatory condition that causes microvascular inflammation with the production of various auto-antibodies that play a major role in its pathogenesis. SLE can affect both sexes, all ages, and all ethnic groups with widespread geographical and socioeconomic backgrounds. Asia encompasses people of many sociocultural backgrounds with diverse ethnic. Due to a lack of national epidemiological research, the incidence and prevalence of SLE in Middle Eastern and Arab countries, have only recently been studied...
November 28, 2018: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
D Kelly, S McErlean, K Naff
Aim To evaluate the effectiveness of formal leadership training amongst medical trainees and to review the current literature in this area. Methods A literature review of all PubMed cited articles on Physician Leadership from November 2015 to July 2017 was undertaken. Twenty exemplary articles on physician leadership were identified. Fifteen out of 20 were surveys, several of which included a qualitative component, Two out of 20 were cross-sectional analysis and 3/20 involved structured interviews. Overall findings showed that, formalised teaching of leadership tools is associated with improvements in emotional intelligence, self-confidence, and enhanced relationships with colleagues...
April 19, 2018: Irish Medical Journal
K Dunn, E Rydzewska, C MacIntyre, J Rintoul, S-A Cooper
BACKGROUND: Little is known about the population prevalence of co-occurring intellectual disabilities and autism, and its impact on general health status. The study aimed to investigate this, in comparison with the general population. METHOD: Whole country data from Scotland's Census, 2011, were analysed. Descriptive statistics were generated; chi-squared tests were undertaken; and logistic regressions were undertaken both with the whole general population data, adjusted for age and gender, and within the population with co-occurring intellectual disabilities and autism...
November 28, 2018: Journal of Intellectual Disability Research: JIDR
N Raimondi, A Quintero Villareal, A Valdivia Nuñez, M C Martín Delgado
The Pan-American and Iberian Federation of Critical Medicine and Intensive Therapy, A.C. (FEPIMCTI), has prepared its Strategic Plan for the next 5 years. In this Plan, it defines its course towards the future, establishes its long-term objectives and works to achieve success. Its strategic objectives are framed in consolidating the legal, fiscal and administrative structure, the updating of its statutes, the implementation of a process management system encompassed in a quality culture, the implementation of committees of experts, achieving academic excellence by developing training programs and giving visibility to the Federation...
October 25, 2018: Medicina Intensiva
Shirin Hamed Azzam, Swan Kang, Mario Salvi, Daniel G Ezra
BACKGROUND: Thyroid eye disease (TED) is an autoimmune disorder that constitutes a major clinical and therapeutic challenge. Current treatment options for moderate-to-severe TED include immunotherapy, orbital radiotherapy and decompression surgery. Limited drugs of proven efficacy are available for the treatment of people with TED. Given the role in the pathogenesis of TED of interleukin (IL)-6 expression in adipocytes, fibroblasts and macrophages, the proposed theory is that inhibition of IL-6 by tocilizumab may be an effective treatment in TED by directly reducing the inflammatory response...
November 27, 2018: Cochrane Database of Systematic Reviews
Jennie C De Gagne, Sang S Kim, Ellen R Schoen, Hyeyoung K Park
BACKGROUND: Web-based education is one of the leading learning pedagogies in health professions education. Students have access to a multitude of opinions, knowledge, and resources on Web, but communication among students in Web-based courses is complicated. Technology adds a filter that makes it difficult to decipher the emotions behind words or read nonverbal cues. This is a concern because students benefit more from Web-based classes when they have a high perception of social presence...
November 26, 2018: JMIR Medical Education
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