Denise Aldrian, Clemens Bochdansky, Anna M Kavallar, Christoph Mayerhofer, Asma Deeb, Abdelhadi Habeb, Andrea Romera Rabasa, Anuradha Khadilkar, Ahmet Uçar, Birgit Knoppke, Dimitrios Zafeiriou, Mariarosaria Lang-Muritano, Mohamad Miqdady, Sylvia Judmaier, Valerié McLin, Viktoriya Furdela, Thomas Müller, Georg F Vogel
BACKGROUND AND AIMS: To systematically review the literature for reports on Wolcott-Rallison syndrome, focusing on the spectrum and natural history, genotype-phenotype correlations, patient and native liver survival, and long-term outcomes. METHODS: PubMed, Livio, Google Scholar, Scopus and Web of Science databases were searched. Data on genotype, phenotype, therapy, cause of death and follow-up were extracted. Survival and correlation analyses were performed. RESULTS: Sixty-two studies with 159 patients met the inclusion criteria and additional 30 WRS individuals were collected by personal contact...
January 17, 2024: Liver International: Official Journal of the International Association for the Study of the Liver