Xi Zhou, Quan Zhou, Zhaozhi He, Yi Xiao, Yan Liu, Zhuohang Huang, Yaoji Sun, Jiawei Wang, Zhengdong Zhao, Xiaozhou Liu, Bin Zhou, Lei Ren, Yu Sun, Zhiwei Chen, Xingcai Zhang
Reactive oxygen species (ROS) plays important roles in living organisms. While ROS is a double-edged sword, which can eliminate drug-resistant bacteria, but excessive levels can cause oxidative damage to cells. A core-shell nanozyme, CeO2 @ZIF-8/Au, has been crafted, spontaneously activating both ROS generating and scavenging functions, achieving the multi-faceted functions of eliminating bacteria, reducing inflammation, and promoting wound healing. The Au Nanoparticles (NPs) on the shell exhibit high-efficiency peroxidase-like activity, producing ROS to kill bacteria...
March 21, 2024: Nano-Micro Letters