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Intraventricular Haemorrhage

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https://www.readbyqxmd.com/read/30104314/validation-of-the-ich-score-in-patients-with-spontaneous-intracerebral-haemorrhage-admitted-to-the-intensive-care-unit-in-southern-spain
#1
Sonia Rodríguez-Fernández, Encarnación Castillo-Lorente, Francisco Guerrero-Lopez, David Rodríguez-Rubio, Eduardo Aguilar-Alonso, Jesús Lafuente-Baraza, Francisco Javier Gómez-Jiménez, Juan Mora-Ordóñez, Ricardo Rivera-López, María Dolores Arias-Verdú, Guillermo Quesada-García, Miguel Ángel Arráez-Sánchez, Ricardo Rivera-Fernández
OBJECTIVE: Validation of the intracerebral haemorrhage (ICH) score in patients with a diagnosis of spontaneous ICH admitted to the intensive care unit (ICU). METHODS: A multicentre cohort study was conducted in all consecutive patients with ICH admitted to the ICUs of three hospitals with a neurosurgery department between 2009 and 2012 in Andalusia, Spain. Data collected included ICH, Glasgow Coma Scale (GCS) and Acute Physiology and Chronic Health Evaluation II (APACHE-II) scores...
August 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/30104281/successful-treatment-of-extensively-drug-resistant-acinetobacter-baumannii-ventriculitis-with-intravenous-plus-intraventricular-tigecycline-a-case-report
#2
Yan Liu, Zenghui Pu, Maomao Zhao
A 70-year-old woman was adimittetd with subarachnoid haemorrhage. The patient underwent cerebral aneurysm embolization. On hospital day 14, the patient underwent a lumbar subarachnoid continuous drain insertion because of fever and enlarged ventricles were showed on the head computed tomography. On hospital day 19, the patient presented with remittent fever (peak at 39.1 °C) associated with altered mental status. Cerebro-Spinal Fluid (CSF) revealed white blood cell (WBC) count of 53484/mm3 (polymorphonucleocytes,75...
August 13, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/30084487/apolipoprotein-e-gene-polymorphisms-and-intraventricular-haemorrhage-in-infants-born-preterm-a-large-prospective-multicentre-cohort-study
#3
Mark Dzietko, Soeren Schulz, Michael Preuss, Christoph Haertel, Anja Stein, Ursula Felderhoff-Mueser, Wolfgang Goepel
AIM: Infants born preterm are at risk of intraventricular haemorrhage (IVH) but individual susceptibility related to genes is not well defined in this vulnerable population. Apolipoprotein genotypes APOE2 and APOE4 increase the hazard of cerebral haemorrhages in adults. We investigated whether APOE is associated with prevalence of IVH and is likely to have a particular genotype. METHOD: In this prospective study, 5075 infants born preterm with genotype APOE3 were compared to 965 (APOE2) and 1912 (APOE4) individuals, to analyse the association between APOE genotype and grade III and IV IVH...
August 7, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30084424/intraventricular-haemorrhage-as-the-first-manifestation-of-congenital-cytomegalovirus-infection
#4
Malgorzata Sobolewska-Pilarczyk, Katarzyna Pawlak-Osinska, Sylwia Drewa, Beata Smok, Małgorzata Pawlowska
Congenital Cytomegalovirus infection (CCMV) is the most common intrauterine infection. Early diagnosis of CCMV is hindered by three factors: There is no screening programme for CMV infection in pregnant women; a high percentage of infections in neonates are asymptomatic; the clinical signs of CCMV infection are uncharacteristic. The aim of this article is to analyse the clinical picture and course of CCMV treatment in a 3-week-old newborn, analyse adverse events in 14-week-long antiviral therapy and also assess intraventricular bleeding as an early indicator for the diagnosis of CCMV...
April 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/30066181/relationship-of-resuscitation-respiratory-function-monitoring-data-and-outcomes-in-preterm-infants
#5
Anoop Pahuja, Katie Hunt, Vadivelam Murthy, Prashanth Bhat, Ravindra Bhat, Anthony D Milner, Anne Greenough
Intraventricular haemorrhage (IVH) and bronchopulmonary dysplasia (BPD) are major complications of premature birth. We tested the hypotheses that prematurely born infants who developed an IVH or BPD would have high expiratory tidal volumes (VTE ) (VTE  > 6 ml/kg) and/or low-end tidal carbon dioxide (ETCO2 ) levels (ETCO2 levels < 4.5 kPa) as recorded by respiratory function monitoring or hyperoxia (oxygen saturation (SaO2 ) > 95%) during resuscitation in the delivery suite. Seventy infants, median gestational age 27 weeks (range 23-33), were assessed; 31 developed an IVH and 43 developed BPD...
July 31, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29951217/racial-differences-in-intracerebral-haemorrhage-outcomes-in-patients-with-obesity
#6
I Iwuchukwu, N Mahale, J Ryder, B Hsieh, B Jennings, D Nguyen, K Cornwell, R Beyl, J Zabaleta, M Sothern
Objective: This study was conducted to determine the role of obesity and race in intracerebral haemorrhage (ICH) outcomes. Methods: The Get with the guideline-Stroke database was queried for all admitted patients with spontaneous ICH. Secondary causes of ICH were excluded. Body mass index (BMI) was classified using the Center for Disease Control guidelines. Race was classified as White or non-White. Demographics, clinical, imaging data were retrieved. Outcome measures were hematoma expansion at 24 h and discharge disposition...
June 2018: Obesity Science & Practice
https://www.readbyqxmd.com/read/29889578/a-new-modified-neuroendoscope-technology-to-remove-severe-intraventricular-haematoma
#7
Bo Du, Ai-Jun Shan, Yu-Ping Peng, Jin Wang, Kai-Wen Peng, Xian-Liang Zhong, Yujuan Zhang
BACKGROUND: Minimally invasive endoscopic haematoma evacuation is widely used in the treatment of intraventricular haemorrhage. However, its technique still has room for improvement. A new modified neuroendoscope technology (MNT) was used in this study and we explored its safety and efficacy in the treatment of severe acute intraventricular haemorrhage by comparing it with extraventricular drainage plus urokinase thrombolytic (EVD + UT) therapy. METHODS: The following parameters were compared between the MNT group and the control group: incision design, operation time, ICU monitoring time, ventricular drainage tube (VDT) placement time, post-operative drainage tube obstruction (PDTO) rate, post-operative complications rate, 6-month mortality and Glasgow Outcome Scale (GOS)...
2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29851196/does-earlier-arrival-of-the-retrieval-team-improve-short-term-outcomes-in-outborn-extremely-premature-infants
#8
Janet B Sharpe, Mark W Davies
AIM: The risk of mortality and morbidity is increased in outborn, extremely premature infants. We aim to determine whether earlier arrival of the retrieval team after the birth of infants less than 29 weeks gestation improves short-term mortality and morbidity. METHODS: This is a retrospective analysis of a cohort of infants less than 29 weeks gestation who were retrieved to the Royal Brisbane and Women's Hospital (RBWH) over a 5-year period. Demographic information regarding the infant and mother, retrieval team arrival time and outcome data was collected...
May 31, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29848541/intraventricular-haemorrhage-and-obstructive-hydrocephalus-in-a-term-neonate-an-uncommon-presentation-of-haemophilia-b
#9
Deepanjan Bhattacharya, Indar Kumar Sharawat, Lokesh Saini
No abstract text is available yet for this article.
May 30, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29806081/neurodevelopmental-outcome-of-nutritional-intervention-in-newborn-infants-at-risk-of-neurodevelopmental-impairment-the-dolphin-neonatal-double-blind-randomized-controlled-trial
#10
Morag J Andrew, Jeremy R Parr, Christine Montague-Johnson, Karen Laler, Jane Holmes, Bonny Baker, Peter B Sullivan
AIM: To investigate whether neonates at risk for neurodevelopmental impairment have improved neurodevelopment after docosahexaenoic acid, choline, and uridine-5-monophosphate supplementation versus controls. METHOD: Recruitment was from UK neonatal units. Eligible for inclusion were infants born at less than 31 weeks' gestation with a weight less than the ninth centile; infants born at less than 31 weeks' gestation with a grade II or higher intraventricular haemorrhage/preterm white matter injury; infants born between 31 weeks' and 40 weeks' gestation plus 28 days with a grade II or higher intraventricular haemorrhage/preterm white matter injury, moderate or severe hypoxic-ischaemic encephalopathy, or defined neuroimaging abnormalities...
May 27, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29790271/correlation-between-neonatal-outcomes-of-twins-depends-on-the-outcome-secondary-analysis-of-twelve-randomised-controlled-trials
#11
L N Yelland, E Schuit, J Zamora, P F Middleton, A C Lim, A H Nassar, L Rode, V Serra, E A Thom, C Vayssière, Bwj Mol, S Gates
OBJECTIVE: To estimate the magnitude of the correlation between neonatal outcomes of twins and demonstrate how this information can be used in the design of randomised controlled trials (RCTs) in women with twin pregnancies. DESIGN: Secondary analysis of data from 12 RCTs. SETTING: Obstetric care in multiple countries, 2004-2012. POPULATION OR SAMPLE: 4504 twin pairs born to women who participated in RCTs to assess treatments given during pregnancy...
May 22, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29730594/adverse-effects-of-small-for-gestational-age-differ-by-gestational-week-among-very-preterm-infants
#12
Erik A Jensen, Elizabeth E Foglia, Kevin C Dysart, Rebecca A Simmons, Zubair H Aghai, Alison Cook, Jay S Greenspan, Sara B DeMauro
OBJECTIVE: To characterise the excess risk for death, grade 3-4 intraventricular haemorrhage (IVH), bronchopulmonary dysplasia (BPD) and stage 3-5 retinopathy of prematurity independently associated with birth small for gestational age (SGA) among very preterm infants, stratified by completed weeks of gestation. METHODS: Retrospective cohort study using the Optum Neonatal Database. Study infants were born <32 weeks gestation without severe congenital anomalies...
May 5, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29726010/lower-versus-higher-oxygen-concentrations-titrated-to-target-oxygen-saturations-during-resuscitation-of-preterm-infants-at-birth
#13
REVIEW
Kei Lui, Lisa J Jones, Jann P Foster, Peter G Davis, See Kwee Ching, Ju Lee Oei, David A Osborn
BACKGROUND: Initial resuscitation with air is well tolerated by most infants born at term. However, the optimal fractional inspired oxygen concentration (FiO2 - proportion of the breathed air that is oxygen) targeted to oxygen saturation (SpO2 - an estimate of the amount of oxygen in the blood) for infants born preterm is unclear. OBJECTIVES: To determine whether lower or higher initial oxygen concentrations, when titrated according to oxygen saturation targets during the resuscitation of preterm infants at birth, lead to improved short- and long-term mortality and morbidity...
May 4, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29695729/cerebral-oxygen-saturation-and-peripheral-perfusion-in-the-extremely-premature-infant-with-intraventricular-and-or-pulmonary-haemorrhage-early-in-life
#14
Thierry P Beausoleil, Marie Janaillac, Keith J Barrington, Anie Lapointe, Mathieu Dehaes
Extremely preterm infants are at higher risk of pulmonary (PH) and intraventricular (IVH) haemorrhage during the transitioning physiology due to immature cardiovascular system. Monitoring of haemodynamics can detect early abnormal circulation that may lead to these complications. We described time-frequency relationships between near infrared spectroscopy (NIRS) cerebral regional haemoglobin oxygen saturation (CrSO2 ) and preductal peripheral perfusion index (PI), capillary oxygen saturation (SpO2 ) and heart rate (HR) in extremely preterm infants in the first 72 h of life...
April 25, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29662731/intraventricular-haemorrhage-complicated-by-hydrocephalus-in-an-acutely-encephalopathic-preterm-infant
#15
Kene Maduemem, Sameen Khalid, Maya Hariharan, Aamer Siddique
Intraventricular haemorrhage (IVH) is characterized by bleeding of the immature subependymal germinal matrix in preterm infants, but the pathogenesis is multifactorial. IVH and posthaemorrhagic hydrocephalus (PHH) are common causes of neonatal morbidity and mortality among preterm infants. We describe a preterm male infant who was born clinically stillbirth; became moderately severe encephalopathic. He had bilateral IVH (III right and IV left) with consequent PHH. His incredible outcome following a stormy perinatal period appears intriguing...
February 15, 2018: Curēus
https://www.readbyqxmd.com/read/29622414/-impact-of-screening-and-treatment-of-low-systemic-blood-flow-in-the-prevention-of-severe-intraventricular-haemorrhage-and-or-death-in-pre-term-infants
#16
Ignacio Oulego Erroz, Paula Alonso Quintela, Aquilina Jiménez Gonzalez, Sandra Terroba Seara, Silvia Rodríguez Blanco, María Rosón Varas, Leticia Castañón López
OBJECTIVE: To assess the effect of a protocolised intervention for low systemic blood flow (SBF) in the occurrence of severe intraventricular haemorrhage (IVH) or death in pre-term infants. METHODS: A study with a quasi-experimental design with retrospective controls was conducted on pre-term infants of less than 30weeks of gestational age, born between January 2016 and July 2017, who were consecutively included in the intervention period. The control cohort included pre-term infants (born between January 2013 and December 2015) matched by gestational age, birth weight, and gender (two controls for each case)...
April 2, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29550804/autologous-cord-blood-transfusion-in-preterm-infants-could-its-humoral-effect-be-the-kez-to-control-prematurity-related-complications-a-preliminary-study
#17
M Kotowski, Z Litwinska, P Klos, E Pius-Sadowska, E Zagrodnik-Ulan, P Ustianowski, J Rudnicki, B Machalinski
Umbilical cord blood (UCB), rich in stem/progenitor cells, is partially eliminated from the bloodstream during childbirth because the cord is immediately clamped. We hypothesize that transfusion of autologous UCB to premature infants after delivery could serve as an adjuvant modality for preventing the development of prematurity-related complications. We randomly enrolled 20 preterm infants born before 32 weeks of gestational age (GA), all of whom developed anemia, necessitating transfusion of red blood cells (RBCs)...
December 2017: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/29524311/correlation-of-morphological-parameters-and-visual-acuity-with-neurological-development-in-former-preterm-children-aged-4-10-years
#18
Achim Fieß, Ruth Kölb-Keerl, Alexander K Schuster, Markus Knuf, Bernd Kirchhof, Philipp S Muether, Jacqueline Bauer
PURPOSE: The objective of this study was to investigate the relationship between visual acuity, peripapillary retinal nerve fibre layer (pRNFL), retinal thickness at the fovea and other factors with the neurologic status of former preterm children. METHODS: In this cross-sectional hospital based study in a maximum care tertiary centre, detailed anthropometric and ophthalmological data of former preterm children ranging from 4 to 10 years of age with a gestational age (GA) ≤32 weeks were assessed...
March 9, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29516473/provision-of-respiratory-support-compared-to-no-respiratory-support-before-cord-clamping-for-preterm-infants
#19
REVIEW
Michael P Meyer, Elizabeth Nevill, Maisie M Wong
BACKGROUND: Placental transfusion (by means of delayed cord clamping (DCC), cord milking, or cord stripping) confers benefits for preterm infants. It is not known if providing respiratory support to preterm infants before cord clamping improves outcomes. OBJECTIVES: To assess the efficacy and safety of respiratory support provided during DCC compared with no respiratory support during placental transfusion (in the form of DCC, milking, or stripping) in preterm infants immediately after delivery...
March 8, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29505664/higher-versus-lower-amino-acid-intake-in-parenteral-nutrition-for-newborn-infants
#20
REVIEW
David A Osborn, Tim Schindler, Lisa J Jones, John Kh Sinn, Srinivas Bolisetty
BACKGROUND: Sick newborn and preterm infants frequently are not able to be fed enterally, necessitating parenteral fluid and nutrition. Potential benefits of higher parenteral amino acid (AA) intake for improved nitrogen balance, growth, and infant health may be outweighed by the infant's ability to utilise high intake of parenteral AA, especially in the days after birth. OBJECTIVES: The primary objective is to determine whether higher versus lower intake of parenteral AA is associated with improved growth and disability-free survival in newborn infants receiving parenteral nutrition...
March 5, 2018: Cochrane Database of Systematic Reviews
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