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Glycemic control for diabetes patient

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https://www.readbyqxmd.com/read/30335241/feeding-in-adults-with-type-ii-diabetes-mellitus-in-three-public-hospitals-in-cundinamarca-colombia
#1
Ana Yibby Forero, Jenny Alexandra Hernández, Sandra Milena Rodríguez, Jhon Jairo Romero, Gina Emely Morales, Gabriel Ángel Ramírez
Introduction: Type II diabetes mellitus (DMII) is one of the main causes of morbidity and mortality both worldwide and in Colombia. It mainly affects men and women over 45 years of age. Inadequate control of this disease can generate greater health complications making it one of the most costly diseases in the country. Treatment includes activities other than glycemic control and requires constant monitoring by medical personnel and educational processes directed at the patient and his or her family. Objective: To characterize the feeding of patients with DMII in three public hospitals of Cundinamarca...
September 1, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/30333397/sleeve-gastrectomy-induced-remission-of-slowly-progressive-type-1-diabetes-in-a-morbidly-obese-japanese-patient
#2
Jun-Ya Hironaka, Seiichi Kitahama, Hiroyuki Sato, Maki Inoue, Tetsuya Takahashi, Yoshikazu Tamori
The effects of bariatric/metabolic surgery on glycemic control in obese type 1 diabetic patients are controversial. We herein report a case of a morbidly obese 35-year-old woman who completely recovered from slowly progressive type 1 diabetes (SPIDDM) following laparoscopic sleeve gastrectomy. Preoperatively, her body mass index (BMI) was 49.8 kg/m2 and hemoglobin A1c was 5.7% with intensive insulin therapy. Six months after bariatric/metabolic surgery, her BMI decreased to 33.2 kg/m2 and her glycemic control was normal despite the discontinuation of all diabetic medicine...
October 17, 2018: Internal Medicine
https://www.readbyqxmd.com/read/30333278/plant-based-diet-for-hba1c-reduction-in-type-2-diabetes-mellitus-an-evidence-based-case-report
#3
Denita Biyanda Utami, Ardi Findyartini
BACKGROUND: diabetes has become a major public health concern with an estimated 180 million cases worldwide. Nutritional changes are one of the key aspects in the management of type 2 diabetes mellitus. Previous studies have suggested an association between vegetarian diets and improvements in glycemic control in type 2 diabetes mellitus, however the relationship is not well established. The aim of this report is to perform a critical appraisal to analyze whether plant-based diet reduces the HbA1c level compared to conventional diet...
July 2018: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/30329127/metformin-use-and-gastric-cancer-risk-in-diabetic-patients-after-helicobacter-pylori-eradication
#4
Ka Shing Cheung, Esther W Chan, Angel Y S Wong, Lijia Chen, Wai Kay Seto, Ian C K Wong, Wai K Leung
Background: Although prior studies showed metformin could reduce gastric cancer (GC) risk in patients with diabetes mellitus, they failed to adjust for Helicobacter pylori infection and glycemic control. We aimed to investigate whether metformin reduced GC risk in H. pylori-eradicated diabetic patients and its association with glycemic control. Methods: This was a territory-wide cohort study using hospital registry database, recruiting all diabetic patients who were prescribed clarithromycin-based triple therapy for H...
October 16, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/30328788/race-in-older-but-not-younger-patients-associated-with-greater-glycemic-burden-in-primary-care-patients
#5
Jane L Tucker, Kimberly A Zoberi, Denise R Hooks-Anderson, Joanne Salas, Jeffrey F Scherrer
Purpose The purpose of this study is to determine if race disparities in glycemic control differ in young vs older white and African American patients with diabetes. Methods Electronic medical record data were gathered from 1431 primary care patients ≥18 years old, diagnosed with type 2 diabetes, who had ≥2 A1C measurements between July 1, 2008, and June 30, 2015. A1C values were used to compute the average monthly glycemic burden (AMGB). AMGB is the average monthly cumulative amount of A1C >7.5. Age-stratified (18-50 vs >50 years old) linear regression models were computed to measure the association between race and AMGB before and after adjusting for covariates...
October 17, 2018: Diabetes Educator
https://www.readbyqxmd.com/read/30328578/normal-blood-glucose-and-high-blood-ketones-in-a-critically-unwell-patient-with-t1dm-post-bariatric-surgery-a-case-of-euglycemic-diabetic-ketoacidosis
#6
Jemma Dowsett, Rebecca Humphreys, Robert Krones
Obesity is a global epidemic. Obesity in those with type I diabetes (T1DM) contributes to poor glycemic control and complications. Bariatric surgery as management for obesity is increasing in those with T1DM. However, there is limited data pertaining to these patients and their potential post-operative complications. These complications include severe hyperglycemia and diabetic ketoacidosis (DKA). This case study describes a 43-year-old woman with T1DM whose post-operative period following her bariatric surgery was complicated by euglycemic DKA...
October 17, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/30328516/fat-versus-carbohydrate-based-energy-restricted-diets-for-weight-loss-in-patients-with-type-2-diabetes
#7
REVIEW
Osama Hamdy, Mhd Wael Tasabehji, Taha Elseaidy, Shaheen Tomah, Sahar Ashrafzadeh, Adham Mottalib
PURPOSE OF REVIEW: The prevalence of combined obesity and diabetes has increased dramatically in the last few decades. Although medical and surgical weight management are variably effective in addressing this epidemic, it is essential to parallel these strategies with a hypocaloric diet comprising the appropriate macronutrient composition to induce weight loss, enhance glycemic control, and improve cardiovascular risk factors. This review reports the current evidence of the role of carbohydrates and fat-based diets for weight management in patients with combined type 2 diabetes (T2D) and obesity...
October 17, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/30327362/pumps-or-multiple-daily-injections-in-pregnancy-involving-type-1-diabetes-a-prespecified-analysis-of-the-conceptt-randomized-trial
#8
Denice S Feig, Rosa Corcoy, Lois E Donovan, Kellie E Murphy, Jon F R Barrett, J Johanna Sanchez, Tim Wysocki, Katrina Ruedy, Craig Kollman, George Tomlinson, Helen R Murphy
OBJECTIVE: To compare glycemic control, quality of life, and pregnancy outcomes of women using insulin pumps and multiple daily injection therapy (MDI) during the Continuous Glucose Monitoring in Type 1 Diabetes Pregnancy Trial (CONCEPTT). RESEARCH DESIGN AND METHODS: This was a prespecified analysis of CONCEPTT involving 248 pregnant women from 31 centers. Randomization was stratified for pump versus MDI and HbA1c . The primary outcome was change in HbA1c from randomization to 34 weeks' gestation...
October 16, 2018: Diabetes Care
https://www.readbyqxmd.com/read/30325832/preoperative-hypoglycemia-increases-infection-risk-after-trigger-finger-injection-and-release
#9
Patrick J Buchanan, Tsun Law, Sam Rosas, Zachary Hubbard, Bruce A Mast, Harvey Chim
BACKGROUND: Diabetes mellitus is a well-known risk factor for infection after trigger finger (TF) injection and/or release. However, the effect of preoperative hypoglycemia before TF injection or release is currently unknown. The purpose of this study is to determine the effects of preoperative hypoglycemia on infection incidence after TF injection or release. METHODOLOGY: A retrospective cohort review between 2007 and 2015 was conducted using a national private payer database within the PearlDiver Supercomputer...
October 15, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/30325692/determinants-of-fasting-hyperglucagonemia-in-patients-with-type-2-diabetes-and-nondiabetic-control-subjects
#10
Mia Demant, Jonatan I Bagger, Malte P Suppli, Asger Lund, Mette Gyldenløve, Katrine B Hansen, Kristine J Hare, Mikkel Christensen, David P Sonne, Jens J Holst, Tina Vilsbøll, Filip K Knop
BACKGROUND: Fasting hyperglucagonemia can be detrimental to glucose metabolism in patients with type 2 diabetes (T2D) and may contribute to metabolic disturbances in obese and/or prediabetic subjects. However, the mechanisms underlying fasting hyperglucagonemia remain elusive. METHODS: We evaluated the interrelationship between fasting hyperglucagonemia and demographic and biochemical parameters in 106 patients with T2D (31% female, age: 57 ± 9 years [mean ± standard deviation; body mass index (BMI): 30...
October 16, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/30325656/study-of-minimed-640g-insulin-pump-with-smartguard-in-prevention-of-low-glucose-events-in-adults-with-type-1-diabetes-smile-design-of-a-hypoglycemia-prevention-trial-with-continuous-glucose-monitoring-data-as-outcomes
#11
Harold W De Valk, Sandrine Lablanche, Emanuele Bosi, Pratik Choudhary, Julien Da Silva, Javier Castaneda, Linda Vorrink, Simona De Portu, Ohad Cohen
BACKGROUND: Sensor-integrated pump systems with low-glucose suspend (also known as threshold suspend) functions have markedly transformed the management of type 1 diabetes, but most studies to date have excluded patients at high risk of hypoglycemia. The SMILE study is investigating the efficacy of the MiniMed™ 640G insulin pump with the SmartGuard™ predictive low-glucose management (PLGM) feature in the prevention of hypoglycemia in adults with type 1 diabetes, who are at high risk of hypoglycemia...
October 16, 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/30323162/appropriateness-of-using-tests-for-blood-glucose-and-diabetic-complications-in-clinical-practice-experiences-in-a-hospital-in-thailand
#12
Veeravan Lekskulchai
BACKGROUND This study aimed to evaluate how the tests for blood glucose (BG) and diabetic complications have been utilized in a hospital in Thailand. MATERIAL AND METHODS Patient medical records having the results of BG, HbA1c, and/or urine microalbumin presented and the records of DM patients having the results of serum lipids, serum LDL-C, and/or serum creatinine presented were selected. The data of diagnosis, ordered tests, and testing results in these records were extracted for evaluation. RESULTS This study recruited 1066 patients diagnosed with DM and 3081 patients diagnosed with other diseases...
October 16, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/30322810/decreased-plasma-neuregulin-4-levels-are-associated-with-peripheral-neuropathy-in-chinese-patients-with-newly-diagnosed-type-2-diabetes-a-cross-sectional-study
#13
Pijun Yan, Yong Xu, Zhihong Zhang, Chenlin Gao, Jianhua Zhu, Hua Li, Qin Wan
Neuregulin-4 (Nrg4) is a novel adipokine associated with obesity, hyperglycemia, insulin resistance, dislipidemia, inflammation, and oxidative stress in mice and humans. However, no report has demonstrated the relationship of circulating Nrg4 with diabetic peripheral neuropathy (DPN). The objective of our study was to investigate the relationship between circulating Nrg4 and DPN in a cross-sectional study. Circulating Nrg4 levels were determined with an enzyme-linked immunosorbent assays kit in 132 newly diagnosed type 2 diabetes mellitus (nT2DM) patients and 41 normal controls (NC group)...
October 12, 2018: Cytokine
https://www.readbyqxmd.com/read/30322470/-metabolic-control-or-reduction-of-vascular-risk-with-current-treatments-what-is-the-priority
#14
Margarita Alonso Fernández
In patients with type 2 diabetes, tight glycemic control prevents or delays the develop-ment of microvascular complications. In contrast, there is continued debate on the effect of macrovascular complications and the role of early glycaemic control on the ensuing cardiovascular disease. Although large randomised clinical trials have not shown a clearly beneficial effect of intensive control in the short term, subsequent follow-up studies of participants in these trials suggest a favourable cardiovascular effect in the long term...
June 2018: Semergen
https://www.readbyqxmd.com/read/30322468/-use-of-dipeptidyl-peptidase-4-inhibitors-in-patients-with-diabetes
#15
Francisco Carlos Carramiñana Barrera
New drugs have been added to the treatment of type 2 diabetes mellitus. These drugs have represented an advance in the physiopathological approach to the disease, with the possibility of acting on the different mechanisms involved in raised blood glucose levels and allowing treatment to be individualised, as recommended in clinical practice guide-lines and consensus documents. The incretins were added to the therapeutic arsenal of diabetes in 2006. This group in-cludes glucagon-like peptide-1 receptor antagonists and dipeptidyl peptidase-4 inhibitors (marketed in Spain in 2007), which act on the incretin system in the gut, reducing glycae-mia, with a decreasing or neutral effect on weight and with a low risk of hypoglycaemic episodes...
June 2018: Semergen
https://www.readbyqxmd.com/read/30321535/effectiveness-of-artificial-pancreas-in-the-non-adult-population-a-systematic-review-and-network-meta-analysis
#16
REVIEW
Vasilios Karageorgiou, Theodoros G Papaioannou, Ioannis Bellos, Krystallenia Alexandraki, Nikolaos Tentolouris, Christodoulos Stefanadis, George P Chrousos, Dimitrios Tousoulis
OBJECTIVE: Artificial pancreas is a technology that minimizes user input by bridging continuous glucose monitoring and insulin pump treatment, and has proven safety in the adult population. The purpose of this meta-analysis is to evaluate the efficacy of closed-loop (CL) systems in the glycemic control of non-adult type 1 diabetes patients in both a pairwise and network meta-analysis (NMA) context and investigate various parameters potentially affecting the outcome. METHODS: Literature was systematically searched using the MEDLINE (1966-2018), Scopus (2004-2018), Cochrane Central Register of Controlled Trials (CENTRAL) (1999-2018), Clinicaltrials...
October 12, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/30319263/effect-of-pharmaceutical-care-interventions-on-glycemic-control-in-patients-with-diabetes-a-systematic-review-and-meta-analysis
#17
Sohyun Jeong, Minhee Lee, Eunhee Ji
Purpose: Diabetes is a chronic lifelong condition, and adherence to medications and self-monitoring of blood glucose are challenging for diabetic patients. The dramatic increase in the prevalence of diabetes is largely due to the incidence of type 2 diabetes in low- and middle-income countries (LMIc) besides high-income countries (HIc). We aimed to evaluate whether pharmacist care (PC) service model in LMIc and HIc could improve clinical outcomes in diabetic patients by performing a meta-analysis...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/30316635/comparison-of-two-glycemic-discharge-goals-in-ed-patients-with-hyperglycemia-a-randomized-trial
#18
Brian E Driver, Lauren R Klein, Jon B Cole, Matthew E Prekker, Erik T Fagerstrom, James R Miner
STUDY OBJECTIVE: Hyperglycemia is commonly encountered in the ED; the importance of glucose reduction in patients well enough to be discharged is unknown. METHODS: We conducted a prospective, randomized trial of ED patients with hyperglycemia with a glucose value 400-600 mg/dL who were discharged from the ED, excluding those with type 1 diabetes mellitus. Patients were randomly assigned to a discharge glucose goal, <350 mg/dL (moderate control) or < 600 mg/dL (loose control)...
October 5, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/30316386/management-of-diabetes-mellitus-with-glucagonlike-peptide-1-agonist-liraglutide-in-renal-transplant-recipients-a-retrospective-study
#19
J-H Liou, Y-M Liu, C-H Chen
BACKGROUND: Diabetes mellitus (DM) is the major cause of end-stage renal disease (ESRD) in Taiwan. Despite the use of steroids and/or calcineurin inhibitors (CNIs) in renal transplantation (RTx), additional challenges occur when a patient displays persisting metabolic disease, carries on an unhealthy lifestyle, or experiences genetic effects. Although RTx recipients could get better glycemic control by oral anti-diabetic drugs (OADs) or several insulin agents, they still need more than two kinds of medication...
October 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/30312887/a-validated-lc-ms-ms-method-for-simultaneous-determination-of-linagliptin-and-metformin-in-spiked-human-plasma-coupled-with-solid-phase-extraction-application-to-a-pharmacokinetic-study-in-healthy-volunteers
#20
Bahia Abbas Moussa, Marianne Alphonse Mahrouse, Michael Gamal Fawzy
Combination therapy has a pivotal role in type II diabetes mellitus management in patients unable to maintain normal glycemic level using metformin alone. Addition of linagliptin, dipeptidyl peptidase-IV inhibitor, to metformin improves glycemic control. This study is concerned with the development of an HPLC-MS/MS method for simultaneous quantification of linagliptin and metformin in spiked human plasma. The method was applied to evaluate the potential pharmacokinetic interactions between the cited drugs in healthy volunteers...
October 1, 2018: Journal of Pharmaceutical and Biomedical Analysis
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