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JOURNAL ARTICLE
Armin Handzic, Jim Shenchu Xie, Eef Hendriks, Pascal Mosimann, Patrick Nicholson, Jonathan Micieli, Edward Margolin
BACKGROUND: Transverse sinus stenting (TSS) is an increasingly common treatment for patients with idiopathic intracranial hypertension (IIH). However, detailed neuro-ophthalmic evidence on visual and pharmacotherapy outcomes after TSS is scarce and heterogeneous. This study aimed to describe the visual outcomes of patients undergoing TSS for IIH and to ascertain the proportion of patients who could be weaned off intracranial pressure (ICP)-lowering medication postoperatively. METHODS: A retrospective chart review of all patients with IIH from 2 tertiary academic neuro-ophthalmology practices who underwent TSS between 2016 and 2022 was performed...
April 17, 2024: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
#2
JOURNAL ARTICLE
Shuming Guo, Jun Li, Xiaogang Yang, Yanping Qin, Yuexin Zhao, Jinkuan Wei, Haitao Ma, Ziniu Yu, Liqiang Zhao, Yuehuan Zhang
Marine heatwaves (MHWs) have a significant impact on intertidal bivalves and the ecosystems they sustain, causing the destruction of organisms' original habitats. Saccostrea mordax mainly inhabits the intertidal zone around the equator, exhibiting potential tolerance to high temperatures and maybe a species suitable for habitat restoration. However, an understanding about the tolerance mechanism of S. mordax to high temperatures is unclear. It is also unknown the extent to which S. mordax can tolerate repeated heatwaves of increasing intensity and frequency...
April 13, 2024: Science of the Total Environment
#3
Robbert N H Touwslager, C Michel Zwaan, Boudewijn Bakker, Eef G W M Lentjes, Leendert H J Looijenga, Hanneke M van Santen
OBJECTIVES: Childhood cancer survivors are at risk for premature ovarian insufficiency, especially after treatment with alkylating agents. The objective of this report is to highlight a case in which this phenomenon caused a false-positive pregnancy test. CASE PRESENTATION: A workup was performed in a 14-year-old girl with a positive pregnancy test. She was diagnosed with stage IV neuroblastoma of the left adrenal gland at the age of 4 years. She received extensive treatment, including alkylating agents, and had been diagnosed with premature ovarian insufficiency...
April 15, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
#4
JOURNAL ARTICLE
Alexis Heng Boon Chin, Jean-Didier Bosenge Nguma, Charles Nkurunziza, Ningyu Sun, Guoqing Tong
The majority of women who freeze their eggs for non-medical or social reasons, commonly referred to as elective egg freezing (EEF), do not eventually utilize their frozen eggs. This would result in an accumulated surplus of unused frozen eggs in fertility clinics worldwide, which represents a promising source of donation to infertile women undergoing IVF treatment. Rigorous and comprehensive counseling is needed, because the process of donating one's unused surplus frozen eggs involves complex decision-making...
April 2024: Asian Bioethics Review
#5
JOURNAL ARTICLE
Mari J Fujimoto, Eef van der Worp, Beth Kinoshita, Matthew Lampa, Ben J Coldrick, Patrick Caroline
PURPOSE: To investigate the differences in contact lens sagittal depth (CL-SAG), base curve (BC), and overall lens diameter (OAD) of daily disposable (DD) SCLs at room temperature (20 °C) and on-eye (34 °C) temperature. METHODS: Twelve different spherical daily SCLs were analyzed (labeled power -3.00 D) at 20 °C and 34 °C. The posterior CL-SAG, BC, and OAD were measured directly using a spectral domain OCT-based instrument (Optimec is830)...
April 2, 2024: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
#6
JOURNAL ARTICLE
Ashwini Kumar Ray, Anjali Priya, Md Zubbair Malik, Thangavel Alphonse Thanaraj, Alok Kumar Singh, Payal Mago, Chirashree Ghosh, Shalimar, Ravi Tandon, Rupesh Chaturvedi
Cardiovascular disease (CVD) is a collective term for disorders of the heart and blood vessels. The molecular events and biochemical pathways associated with CVD are difficult to study in clinical settings on patients and in vitro conditions. Animal models play a pivotal and indispensable role in CVD research. Caenorhabditis elegans, a nematode species, has emerged as a prominent experimental organism widely utilized in various biomedical research fields. However, the specific number of CVD-related genes and pathways within the C...
March 29, 2024: Scientific Reports
#7
JOURNAL ARTICLE
Zhaolong Pan, Ping He, Daijia Fan, Rong Jiang, Daping Song, Lei Song, Wei Zhou, Wentian He
Vegetables are the most consumed non-staple food globally, and their production is crucial for dietary diversity and public health. Use of enhanced-efficiency fertilizers (EEFs) in vegetable production could improve vegetable yield and quality while reducing reactive nitrogen (Nr) losses. However, different management and environmental factors has significantly distinctive impacts on the effectiveness of EEFs. In this study, a worldwide meta-analysis based on the data collected from 144 studies was performed to assess the impacts of EEF (nitrification inhibitor [NI] and polymer-coated urea [PCU]) application on vegetable yield, nitrogen (N) uptake, nitrogen use efficiency (NUE), quality and Nr losses (nitrous oxide (N2 O) emissions, ammonia (NH3 ) volatilization, and nitrate (NO3 - ) leaching)...
March 26, 2024: Science of the Total Environment
#8
JOURNAL ARTICLE
Gui-Ya Qin, Xiao-Qi Sun, Rui Wang, Jing-Fu Guo, Jian-Xun Fan, Hui Li, Lu-Yi Zou, Ai-Min Ren
It is important to develop materials with environmental stability and long device shelf life for use in organic field-effect transistors (OFETs). The microscopic, molecular-level nature of the organic layer in OFETs is not yet well understood. The stability of geometric and electronic structures and the regulation of the external electric field (EEF) on the charge transport properties of four typical homogeneous organic semiconductors (OSCs) were investigated by density functional theory (DFT). The results showed that under the EEF, the structural changes in single-bond linked oligomers were more sensitive and complex than those of condensed molecules, and there were non-monotonic changes in their reorganization energy ( λ ) during charge transport under an EEF consisting of decreases and then increases (Series D)...
March 20, 2024: Chemical Science
#9
JOURNAL ARTICLE
Xingzhu Tang, Yajie Zhang, Chaofan Sun
In this work, by capitalizing on the density functional theory (DFT) and the time-dependent density functional theory (TD-DFT) methods, it has been systematically studied that the excited state double intramolecular proton transfer (ESDPT) process and the photophysical properties of 1,8-dihydroxy-2-naphthaldehyde (DHNA) are affected by the distinct external electric fields (EEFs). The obtained intramolecular hydrogen bond (IHB) parameters containing bond lengths and angles, as well as infrared (IR) vibrational spectra demonstrate that IHB strength changes in the distinct EEFs...
March 19, 2024: Physical Chemistry Chemical Physics: PCCP
#10
JOURNAL ARTICLE
My Nghe Tran, Myriam Moreau, Ahmed Addad, Adrien Teurtrie, Thomas Roland, Vincent de Waele, Marc Dewitte, Louis Thomas, Gaëtan Levêque, Chunyang Dong, Pardis Simon, Karima Ben Tayeb, David Mele, Vitaly Ordomsky, Bruno Grandidier
Among semiconductor nanomaterials, titanium dioxide is at the forefront of heterogeneous photocatalysis, but its catalytic activity greatly suffers from the loss of photoexcited charge carriers through deleterious recombination processes. Here, we investigate the impact of an external electric field (EEF) applied to conventional P25 TiO2 nanopowder with or without Au nanoparticles (NPs) to circumvent this issue. The study of two redox reactions in the gas phase, water splitting and toluene degradation, reveals an enhancement of the photocatalytic activity with rather modest electric fields of a few volt/centimeters only...
March 19, 2024: ACS Applied Materials & Interfaces
#11
JOURNAL ARTICLE
Amin Ebrahimi, Shahrokh Gharanjik, Elham Azadvari, Sajad Rashidi-Monfared
BACKGROUND: Quantifying gene expression is a critical aspect of applied genomics research across all organisms, and real-time PCR has emerged as a powerful tool for this purpose. However, selecting appropriate internal control genes for data normalization presents specific challenges. This study aimed to identify suitable reference genes for gene expression analysis under various conditions, encompassing salinity, low and high-temperature stresses, and different elicitor treatments. These treatments included titanium dioxide, cold plasma, 24-epibrassinolide, and melatonin, resulting in a total of 13 unique treatments and 148 treatment combinations applied to fenugreek plants...
March 16, 2024: Plant Methods
#12
JOURNAL ARTICLE
Ming Jun Kuck, Eef Hogervorst
INTRODUCTION: With the number of menopausal women projected estimated to reach 1.2 billion by 2030 worldwide, it is critically important to understand how menopause may affect women's emotional well-being and how many women are affected by this. This study aimed to explore (i) the relationship between psychological complaints (depression, anxiety, poor memory) across different menopausal stages and (ii) investigate the correlation between resilience, self-efficacy, and perceived stress levels, with psychological complaints and whether this was associated with menopausal stage and/or age...
2024: Frontiers in Psychiatry
#13
JOURNAL ARTICLE
Torsten Witt, Nicole Robinson, Ana C Palma, Lucas A Cernusak, Steven Pratt, Matthew Redding, Damien J Batstone, Susanne Schmidt, Bronwyn Laycock
Enhanced efficiency fertilizers (EEFs) can reduce nitrogen (N) losses in temperate agriculture but are less effective in the tropics. We aimed to design a new EEF and evaluate their performance in simple-to-complex tests with tropical soils and crops. We melt-extruded urea at different loadings into biodegradable polymer matrix composites using biodegradable polyhydroxyalkanoate (PHA) or polybutylene adipate-co-terephthalate (PBAT) polymers with urea distributed throughout the pellet. These contrast with commercially coated EEF that have a polymer-coated urea core...
March 7, 2024: Journal of Environmental Quality
#14
JOURNAL ARTICLE
Jose Danilo Bengzon Diestro, Robert Fahed, Abdelsimar Tan Omar, Christine Hawkes, Eef J Hendriks, Clare Enriquez, Muneer Eesa, Grant Stotts, Hubert Lee, Shashank Nagendra, Alexandre Poppe, Célina Ducroux, Timothy Lim, Karl Narvacan, Michael Rizzuto, Afra Alfalahi, Hidehisa Nishi, Pragyan Sarma, Ze'ev Itsekson Hayosh, Katrina Ignacio, William Boisseau, Eduardo Pimenta Ribeiro Pontes Almeida, Anass Benomar, Mohammed A Almekhlafi, Genvieve Milot, Aviraj Deshmukh, Kislay Kishore, Donatella Tampieri, Jeffrey Wang, Abhilekh Srivastava, Daniel Roy, Federico Carpani, Nima Kashani, Claudia Candale-Radu, Nishita Singh, Maria Bres Bullrich, Robert Sarmiento, Ryan T Muir, Carmen Parra-Fariñas, Stephanie Reiter, Yan Deschaintre, Ravinder-Jeet Singh, Vivek Bodani, Aristeidis Katsanos, Ronit Agid, Atif Zafar, Vitor M Pereira, Julian Spears, Thomas R Marotta, Pascal Djiadeu, Sunjay Sharma, Forough Farrokhyar
BACKGROUND: Limited research exists regarding the impact of neuroimaging on endovascular thrombectomy (EVT) decisions for late-window cases of large vessel occlusion (LVO) stroke. OBJECTIVE: T0 assess whether perfusion CT imaging: (1) alters the proportion of recommendations for EVT, and (2) enhances the reliability of EVT decision-making compared with non-contrast CT and CT angiography. METHODS: We conducted a survey using 30 patients drawn from an institutional database of 3144 acute stroke cases...
March 7, 2024: Journal of Neurointerventional Surgery
#15
JOURNAL ARTICLE
Pasi K Korhonen, Tao Wang, Neil D Young, Joseph J Byrne, Tulio L Campos, Bill C H Chang, Aya C Taki, Robin B Gasser
Advances in single cell technologies are allowing investigations of a wide range of biological processes and pathways in animals, such as the multicellular model organism Caenorhabditis elegans - a free-living nematode. However, there has been limited application of such technology to related parasitic nematodes which cause major diseases of humans and animals worldwide. With no vaccines against the vast majority of parasitic nematodes and treatment failures due to drug resistance or inefficacy, new intervention targets are urgently needed, preferably informed by a deep understanding of these nematodes' cellular and molecular biology - which is presently lacking for most worms...
December 2024: Computational and Structural Biotechnology Journal
#16
JOURNAL ARTICLE
Ahmet Begde, Thomas Wilcockson, Carol Brayne, Eef Hogervorst
Visual processing deficits have frequently been reported when studied in individuals with dementia, which suggests their potential utility in supporting dementia screening. The study uses EPIC-Norfolk Prospective Population Cohort Study data (n = 8623) to investigate the role of visual processing speed assessed by the Visual Sensitivity Test (VST) in identifying the risk of future dementia using Cox regression analyses. Individuals with lower scores on the simple and complex VST had a higher probability of a future dementia diagnosis HR1...
February 29, 2024: Scientific Reports
#17
JOURNAL ARTICLE
Jun Chen, Jiani Xu, Tingting Xiao, Zikai Gao, Mengjie Bo, Zhihui Gu, Peng Ma, Congming Ma
CONTEXT: The influence of external electric fields (EEFs) on chemical substances has always been a hot topic in the field of theoretical chemistry research. 2,6-Diamino-3,5-dinitropyrazine-1-oxide (LLM-105) is an energetic material with excellent comprehensive properties and enormous potential for application. This article explores the molecular structure, electronic structure, energy change, frontier molecular orbitals (FMOs) and density of states (DOS), UV-Vis spectra, and infrared spectra of LLM-105 under various electric field conditions...
February 26, 2024: Journal of Molecular Modeling
#18
JOURNAL ARTICLE
Laura Téblick, Marijana Lipovac, F Ricardo Burdier, Annemie De Smet, Margo Bell, Eef van den Borst, Veerle Matheeussen, Alex Vorsters
BACKGROUND: First-void urine (FVU) provides a non-invasive method for collecting a wide range of biomarkers found in genital tract secretions. To optimize biomarker collection in FVU, this study investigated the impact of naturally present and supplemented precipitating agents: uromodulin (UMOD) and polyethylene glycol (PEG), on the concentration of human papillomavirus (HPV) pseudovirions (PsV), cell-free DNA (cfDNA), and cellular genomic DNA (gDNA) through centrifugation. METHODS: FVU samples from ten healthy female volunteers, along with a control sample, were spiked with seal herpesvirus 1 (PhHV-1) DNA, HPV16 plasmid DNA, and HPV16 PsV with an enhanced green fluorescent protein (EGFP) reporter...
February 17, 2024: European Journal of Medical Research
#19
JOURNAL ARTICLE
Lisa Dreessen, Aziz Debain, Siddhartha Lieten, Bert Bravenboer, Sofie Vermeiren, Roberta Vella-Azzopardi, Veerle Knoop, Axelle Costenoble, Celeste Smeys, Rock-Ange Iranyeza, Kristof E Y Van der Meulen, Eef Vanderhelst, Daniel Schuermans, Ivan Bautmans
INTRODUCTION: This study aimed to evaluate the association of respiratory muscle strength with sarcopenia and its indicators in the oldest old. METHODS: Maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP) and sarcopenia related factors (handgrip strength and appendicular lean mass) were evaluated in a cohort of n=286 (45.5% female) non-frail, community-dwelling persons aged 83.6±3.0 years (age range 80-97 years). RESULTS: The sample presented a sarcopenia prevalence of 32...
February 5, 2024: Gerontology
#20
JOURNAL ARTICLE
Fernando P Cometto, Nicolás Arisnabarreta, Radovan Vanta, Daniela K Jacquelín, Vijay Vyas, Bettina V Lotsch, Patricia A Paredes-Olivera, E Martín Patrito, Magalí Lingenfelder
The reversible formation of hydrogen bonds is a ubiquitous mechanism for controlling molecular assembly in biological systems. However, achieving predictable reversibility in artificial two-dimensional (2D) materials remains a significant challenge. Here, we use an external electric field (EEF) at the solid/liquid interface to trigger the switching of H-bond-linked 2D networks using a scanning tunneling microscope. Assisted by density functional theory and molecular dynamics simulations, we systematically vary the molecule-to-molecule interactions, i...
January 23, 2024: ACS Nano
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