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depression meta

Jennifer Svaldi, Florian Schmitz, Julia Baur, Andrea S Hartmann, Tanja Legenbauer, Charlotte Thaler, Jörn von Wietersheim, Martina de Zwaan, Brunna Tuschen-Caffier
BACKGROUND: Bulimia nervosa (BN), a mental disorder that causes significant impairment, can be treated with psychological, pharmacological, nutrition-based and self-help interventions. We conducted a pre-registered meta-analysis of randomized-controlled trials (RCTs) to assess the efficacy of these interventions in up to 19 different interventions. METHODS: Database search terms were combined for BN and RCTs from database inception to March 2017. Abstinence from binge eating episodes, compensatory behaviors, the absence of a BN diagnosis and reduction of symptom severity were considered as primary outcome variables, reduction of self-reported eating pathology and depression served as secondary outcome variables...
December 5, 2018: Psychological Medicine
Leonie C P Banning, Inez H G B Ramakers, Kay Deckers, Frans R J Verhey, Pauline Aalten
OBJECTIVE: APOE status has been associated to affective symptoms in cognitively impaired subjects, with conflicting results. METHODS: Databases CINAHL, Embase, PsychINFO and PubMed were searched for studies evaluating APOE genotype with affective symptoms in MCI and AD dementia. Symptoms were meta-analyzed separately and possible sources of heterogeneity were examined. RESULTS: Fifty-three abstracts fulfilled the eligibility criteria. No association was found between the individual symptoms and APOE ε4 carriership or zygosity...
December 1, 2018: Neuroscience and Biobehavioral Reviews
Nadine A Vogt, Jan M Sargeant, Melissa C MacKinnon, Ali M Versluis
BACKGROUND: Lyme borreliosis, a tick-borne disease, is endemic to some parts of North America and is an emerging disease in other parts of the world. Vaccination is an increasingly common, although controversial, method used in the prevention of Lyme disease in dogs; the reported efficacies of Borrelia burgdorferi vaccines in dogs are highly variable, ranging from 50% to 100%. OBJECTIVES: To determine the efficacy of vaccines for prevention of Lyme disease in dogs in North America...
December 3, 2018: Journal of Veterinary Internal Medicine
Anees Bahji, Emily R Hawken, Amir A Sepehry, Casimiro A Cabrera, Gustavo Vazquez
OBJECTIVE: In this systematic review and meta-analysis, the response, remission, and speed of response in adults with major depressive disorder (MDD) and bipolar disorder in depressive episode (BDD) receiving an acute course of electroconvulsive therapy (ECT) were quantitatively analyzed. METHODS: Using the PRISMA guidelines, 1660 citations were identified through five electronic databases. 19 articles met final inclusion criteria for meta-analysis. RESULTS: The pooled response and remission rates with ECT in MDD were 74...
December 3, 2018: Acta Psychiatrica Scandinavica
Robert C Smith, Stefan Leucht, John M Davis
RATIONALE: There are many psychotropic drugs available for treatment of schizophrenia. The clinician's choice of the most effective first-line antipsychotic treatment for patients with schizophrenia should balance considerations of differential efficacy of antipsychotics against the relative risk of different side effects. METHOD: We reviewed recent studies using meta-analytic techniques and additional studies of new antipsychotics which quantitatively evaluate the efficacy of side effects of first- and second-generation antipsychotics and studies of the efficacy on add-on secondary medications...
November 30, 2018: Psychopharmacology
Michael J Gitlin
The proper place and the optimal use of antidepressants in treating bipolar depression continues to be an area of great interest and greater controversy with passionate opinions more common than good studies. Even the handful of meta-analyses in the area disagree with each other. Overall, the evidence that antidepressants are effective in treating bipolar depression is weak. Additionally, many experts and clinicians worry greatly about the capacity of antidepressants to cause affective switching or mood destabilization...
December 1, 2018: International Journal of Bipolar Disorders
Katie Tolkien, Steven Bradburn, Chris Murgatroyd
BACKGROUND & AIMS: There is a large body of evidence which supports the role of inflammation in the pathophysiology of mental health disorders, including depression. Dietary patterns have been shown to modulate the inflammatory state, thus highlighting their potential as a therapeutic tool in disorders with an inflammatory basis. Here we conduct a systematic review and meta-analysis of current literature addressing whether there is a link between the inflammatory potential of a diet and risk of depression or depressive symptoms...
November 20, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Juan Ángel Bellón, Sonia Conejo-Cerón, Cayetana Cortés-Abela, José Miguel Pena-Andreu, Antonio García-Rodríguez, Patricia Moreno-Peral
Objectives Psychological and educational interventions for the prevention of depression have a small-to-moderate effect. However, little is known about their effectiveness in the workplace. We aimed to evaluate the effectiveness of such interventions through a systematic review and meta-analysis of randomized controlled trials (RCT). Methods We searched PubMed, PsycINFO, EMBASE, CENTRAL, CIS-DOC and Open Grey for RCT. Search was supplemented with manual searches of reference lists of relevant meta-analyses and trials...
November 30, 2018: Scandinavian Journal of Work, Environment & Health
Xiaobing Yu, Tao Liu, Dewei Zhao, Ke Yang, Xiuzhi Zhang, Meng Zhang, Shuo Zhang, Wei Huang, Baolin Wu, Junlei Li
OBJECTIVE: Pregabalin has been approved for the treatment of the neuropathic pain following spinal cord injury (SCI). We performed a systemic review and meta-analysis of randomized, controlled, multicenter trials to evaluate the efficacy and safety of pregabalin for SCI-induced neuropathic pain. METHODS: Research searching was performed in PubMed and EMBASE databases and the Cochrane library at May 2018. Clinical controlled trials using pregabalin for the pain treatment following SCI in adults (≥18▒y old) were included...
November 28, 2018: Clinical Journal of Pain
Ibrahim Nadeem, Mohammed Zohair Rahman, Yasser Ad-Dab'bagh, Mahmood Akhtar
Depression is one of the most prevalent mental illnesses and is often associated with various other medical disorders. Since the 1980s, the primary pharmacological treatment has been antidepressants, but due to the recent discovery of the association between the gut microbiome and mental health, probiotics have been proposed as an adjunctive or alternate treatment. In this narrative review, we aim to provide a holistic perspective by synthesizing and evaluating existing evidence, discussing key biological mechanisms, exploring the history of probiotic use and appreciating the influence of modern diet on mental health...
November 29, 2018: Psychiatry and Clinical Neurosciences
Alina Rigabert, Emma Motrico, Patricia Moreno-Peral, Davinia M Resurrección, Sonia Conejo-Cerón, Desirée Navas-Campaña, Juan Á Bellón
INTRODUCTION: Although evidence exists for the efficacy of psychosocial interventions in preventing depression, little is known about its prevention through online interventions. The objective of this study is to conduct a systematic review and meta-analysis of randomised controlled trials assessing the effectiveness of online interventions in preventing depression in heterogeneous populations. METHODS AND ANALYSIS: We will conduct a systematic review and meta-analysis of randomised controlled trials that will be identified through searches of PubMed, PsycINFO, WOS, Scopus, OpenGrey, Cochrane Central Register of Controlled Trials, ClinicalTrials...
November 28, 2018: BMJ Open
Xiaosu Bai, Zhiming Liu, Zhisen Li, Dewen Yan
OBJECTIVES: Several patients with type 2 diabetes mellitus (T2DM) have depressive disorders. Whether insulin treatment was associated with increased risk of depression remains controversial. We performed a meta-analysis to evaluate the association of insulin therapy and depression. DESIGN: A meta-analysis. METHODS: We conducted a systematic search of PubMed, PsycINFO, Embase and the Cochrane Library from their inception to April 2016. Epidemiological studies comparing the prevalence of depression between insulin users and non-insulin users were included...
November 28, 2018: BMJ Open
Lisa Jane Brighton, Sophie Miller, Morag Farquhar, Sara Booth, Deokhee Yi, Wei Gao, Sabrina Bajwah, William D-C Man, Irene J Higginson, Matthew Maddocks
BACKGROUND: Breathlessness is a common, distressing symptom in people with advanced disease and a marker of deterioration. Holistic services that draw on integrated palliative care have been developed for this group. This systematic review aimed to examine the outcomes, experiences and therapeutic components of these services. METHODS: Systematic review searching nine databases to June 2017 for experimental, qualitative and observational studies. Eligibility and quality were independently assessed by two authors...
November 29, 2018: Thorax
(no author information available yet)
OBJECTIVEGilles de la Tourette syndrome (GTS) is a disorder characterized by motor and vocal tics. Although by definition the onset of GTS is before age 18 years, clinical trials of deep brain stimulation (DBS) have been conducted only in adults. Using individual participant data (IPD) meta-analysis methodology, the current study investigated the safety and efficacy of DBS as a treatment for GTS in children and youth.METHODSA systematic review with no date or language restrictions was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement...
October 1, 2018: Journal of Neurosurgery. Pediatrics
(no author information available yet)
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes...
November 10, 2018: Lancet
Kristene Cheung, Jennifer Theule
Although there is a consensus that maternal depression is strongly related to child externalizing behaviors, research on the association between paternal depression and child externalizing behaviors is mixed. Some research shows that paternal depressive symptoms are positively associated with symptoms of externalizing behaviors, including oppositional-defiant behavior, conduct problems, and overall externalizing behavior, while other studies failed to find an association, or demonstrated a weak or negative association...
November 29, 2018: Journal of Family Psychology: JFP
Qiuxiang Zhang, Heng Zhao, Yaning Zheng
OBJECTIVE: The purpose of this systematic review and meta-analysis was to evaluate the effectiveness of mindfulness-based stress reduction (MBSR) in breast cancer patients. METHODS: A systematic search of Cochrane Library, Cochrane Central Register of Controlled Trials, PsycINFO database, Web of science, Medline, EMBASE, CNKI, and CBM database was carried out from February to May 2018, with no language restrictions. Trials examining the effects of MBSR versus control group on symptom variables and health-related quality of life were included...
November 28, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Jan Schürmann, Jürgen Margraf
Background/Objective : Based on studies using established psychometric scales, Twenge and coworkers have shown substantial increases in trait anxiety, depressive symptoms and neuroticism in North American population samples since the 1950s. Similar analyses for European samples have not yet been conducted. Our study therefore examined whether similar secular trends exist in German-speaking and British non-clinical samples together with possible connected societal factors. Method : A literature search identified 131 studies ( N = 63,269) using the STAI, BDI or EPI in non-clinical samples between 1964 and 2015...
May 2018: International Journal of Clinical and Health Psychology: IJCHP
Nicoline Normann, Nexhmedin Morina
Background: Metacognitive therapy (MCT) continues to gain increased ground as a treatment for psychological complaints. During the last years, several clinical trials on the efficacy of MCT have been published. The aim of the current study was to provide an updated meta-analytic review of the effect of MCT for psychological complaints. Methods: We conducted a systematic search of trials on MCT for young and adult patients with psychological complaints published until January 2018, using PsycINFO, PubMed, the Cochrane Library, and Google Scholar...
2018: Frontiers in Psychology
Abriham Zegeye, Animut Alebel, Alemu Gebrie, Bekele Tesfaye, Yihalem Abebe Belay, Fentahun Adane, Worku Abie
BACKGROUND: Antenatal depression is more prevalent in low and middle income countries as compared to high income countries. It has now been documented as a global public health problem owing to its severity, chronic nature and recurrence as well as its negative influence on the general health of women and development of children. However, in Ethiopia, there are few studies with highly variable and inconsistent findings. Therefore, the aim of this study was to determine the prevalence of antenatal depression and its determinants among pregnant women in Ethiopia...
November 29, 2018: BMC Pregnancy and Childbirth
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