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https://www.readbyqxmd.com/read/28086770/social-pediatrics-weaving-horizontal-and-vertical-threads-through-pediatric-residency
#1
Meta van den Heuvel, Maria Athina Tina Martimianakis, Rebecca Levy, Adelle Atkinson, Elizabeth Ford-Jones, Michelle Shouldice
BACKGROUND: Social pediatrics teaches pediatric residents how to understand disease within their patients' social, environmental and political contexts. It's an essential component of pediatric residency training; however there is very little literature that addresses how such a broad-ranging topic can be taught effectively. The aim of this study was to determine and characterize social pediatric education in our pediatric residency training in order to identify strengths and gaps. METHODS: A social pediatrics curriculum map was developed, attending to 3 different dimensions: (1) the intended curriculum as prescribed by the Objectives of Training for Pediatrics of the Royal College of Physicians and Surgeons of Canada (RCPSC), (2) the formal curriculum defined by rotation-specific learning objectives, and (3) the informal/hidden curriculum as reflected in resident and teacher experiences and perceptions...
January 13, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28081211/development-and-validation-of-a-clinical-prediction-rule-for-bacteremia-among-maintenance-hemodialysis-patients-in-outpatient-settings
#2
Sho Sasaki, Takeshi Hasegawa, Hiroo Kawarazaki, Atsushi Nomura, Daisuke Uchida, Takahiro Imaizumi, Masahide Furusho, Hiroki Nishiwaki, Shingo Fukuma, Yugo Shibagaki, Shunichi Fukuhara
BACKGROUND: To our knowledge, no reliable clinical prediction rule (CPR) for identifying bacteremia in hemodialysis (HD) patients has been established. The aim of this study was to develop a CPR for bacteremia in maintenance HD patients visiting the outpatient department. METHODS: This multicenter cohort study involved consecutive maintenance HD patients who visited the outpatient clinic or emergency room of seven Japanese institutions between August 2011 and July 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28080111/generalized-movement-representation-in-haptic-perception
#3
Lucile Dupin, Vincent Hayward, Mark Wexler
The extraction of spatial information by touch often involves exploratory movements, with tactile and kinesthetic signals combined to construct a spatial haptic percept. However, the body has many tactile sensory surfaces that can move independently, giving rise to the source binding problem: when there are multiple tactile signals originating from sensory surfaces with multiple movements, are the tactile and kinesthetic signals bound to one another? We studied haptic signal combination by applying the tactile signal to a stationary fingertip while another body part (the other hand or a foot) or a visual target moves, and using a task that can only be done if the tactile and kinesthetic signals are combined...
January 12, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28078420/comprehensive-polyphenol-profiling-of-a-strawberry-extract-fragaria-%C3%A3-ananassa-by-ultra-high-performance-liquid-chromatography-coupled-with-high-resolution-mass-spectrometry
#4
Giorgia La Barbera, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Roberto Samperi, Riccardo Zenezini Chiozzi, Aldo Laganà
The aim of metabolic untargeted profiling is to detect and identify unknown compounds in a biological matrix to achieve the most comprehensive metabolic coverage. In phytochemical mixtures, however, the complexity of the sample could present significant difficulties in compound identification. In this case, the optimization of both the chromatographic and the mass-spectrometric conditions is supposed to be crucial for the detection and identification of the largest number of compounds. In this work, a systematic investigation of different chromatographic and mass-spectrometric conditions is presented to achieve a comprehensive untargeted profiling of a strawberry extract (Fragaria × ananassa)...
January 11, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28078414/application-of-hs-spme-gc-ms-method-for-the-detection-of-active-moulds-on-historical-parchment
#5
Tomasz Sawoszczuk, Justyna Syguła-Cholewińska, Julio M Del Hoyo-Meléndez
The goal of this work was to analyse the profile of microbial volatile organic compounds (MVOCs) emitted by moulds growing on parchment samples, in search of particular volatiles mentioned in the literature as indicators of active mould growth. First, the growth of various moulds on samples of parchment was assessed. Those species that showed collagenolytic activity were then inoculated on two types of media: samples of parchment placed on media and on media containing amino acids that are elements of the structure of collagen...
January 11, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28077238/patterns-of-care-and-clinical-outcomes-in-patients-with-metastatic-renal-cell-carcinoma-results-from-a-tertiary-cancer-center-in-india
#6
Anant Ramaswamy, Amit Joshi, Vanita Noronha, Vijay M Patil, Rushabh Kothari, Arvind Sahu, Ram Abhinav Kannan, Nilesh Sable, Palak Popat, Santosh Menon, Kumar Prabhash
INTRODUCTION: The current treatment of metastatic renal cell carcinoma (mRCC) revolves around targeted agents, which have resulted in a median overall survival of 22 to 26 months in registration trials. However, the outcomes in a non-trial, real-world Indian population have not yet been evaluated. MATERIALS AND METHODS: The present study was a part of a prospective Clinical Trials Registry-India-registered study, the Kidney Cancer Registry, a prospectively maintained kidney cancer registry...
October 19, 2016: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28076375/sensiblesleep-a-bayesian-model-for-learning-sleep-patterns-from-smartphone-events
#7
Andrea Cuttone, Per Bækgaard, Vedran Sekara, Håkan Jonsson, Jakob Eg Larsen, Sune Lehmann
We propose a Bayesian model for extracting sleep patterns from smartphone events. Our method is able to identify individuals' daily sleep periods and their evolution over time, and provides an estimation of the probability of sleep and wake transitions. The model is fitted to more than 400 participants from two different datasets, and we verify the results against ground truth from dedicated armband sleep trackers. We show that the model is able to produce reliable sleep estimates with an accuracy of 0.89, both at the individual and at the collective level...
2017: PloS One
https://www.readbyqxmd.com/read/28074362/the-determination-and-fate-of-disinfection-by-products-from-ozonation-chlorination-of-fulvic-acid
#8
Xin Zhong, Chongwei Cui, Shuili Yu
Ozonation of fulvic acid (FA) can result in diverse intermediate oxidation by-products, significantly affecting disinfection by-product (DBP) formation following chlorination. The objective of this study was to provide insight into ozone reaction intermediates and reveal the possible formation pathway of DBPs from ozonation of FA due to the formation of intermediate oxidation by-products. Aldehydes, aromatic acids, short-chain acids, chloroform, and dichloroacetic acid were detected at various ozone dosage additions...
January 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28073791/rapid-deployment-aortic-replacement-radar-registry-in-spain-a-protocol
#9
Victor Bautista-Hernandez, Natalia Cal-Purriños, Jose M Arribas-Leal, Manuel Carnero-Alcazar, Jose F Gutierrez-Diez, Jose J Cuenca-Castillo
INTRODUCTION: Rapid deployment valves (RDV) represent a newly introduced approach to aortic valve replacement which facilitates surgical implantation and minimally invasive techniques, shortens surgical times and shows excellent haemodynamic performance. However, evidence on their safety, efficacy and potential complications is mostly fitted with small-volume and retrospective studies. Moreover, no current guidelines exist. To improve our knowledge on this technology, The Rapid Deployment Aortic Replacement (RADAR) Registry will be established across Spain with the aim of assessing RDV outcomes in the real-world setting...
January 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28072733/efficacy-and-safety-of-puerarin-injection-in-curing-acute-ischemic-stroke-a-meta-analysis-of-randomized-controlled-trials
#10
Qing-Hua Zheng, Xiao-Li Li, Zhi-Gang Mei, Li Xiong, Qing-Xian Mei, Jin-Feng Wang, Ling-Jing Tan, Song-Bai Yang, Zhi-Tao Feng
BACKGROUND: Previous studies indicated that the puerarin injection has been widely employed in China for the treatment of acute ischemic stroke. We aim to evaluate the efficacy and safety of the puerarin injection for the treatment of acute ischemic stroke. METHODS: A systematic literature search was performed in PUBMED, EMBASE, SPRINGER LINK, Scopus, Cochrane Library, China National Knowledge Infrastructure (CNKI), VIP Journals Database, Wanfang database and the China Biological Medicine database before November 2016, randomized controlled clinical trials (RCTs) of puerarin injection treating acute ischemic stroke were included...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28069885/qualitative-geospatial-methods-of-exploring-person-place-transactions-in-aging-adults-a-scoping-review
#11
REVIEW
Carri Hand, Suzanne Huot, Debbie Laliberte Rudman, Sachindri Wijekoon
PURPOSE: Research exploring how places shape and interact with the lives of aging adults must be grounded in the places where aging adults live and participate. Combined participatory geospatial and qualitative methods have the potential to illuminate the complex processes enacted between person and place to create much-needed knowledge in this area. The purpose of this scoping review was to identify methods that can be used to study person-place relationships among aging adults and their neighborhoods by determining the extent and nature of research with aging adults that combines qualitative methods with participatory geospatial methods...
January 9, 2017: Gerontologist
https://www.readbyqxmd.com/read/28068640/transient-medial-prefrontal-perturbation-reduces-false-memory-formation
#12
Ruud M W J Berkers, Marieke van der Linden, Rafael F de Almeida, Nils C J Müller, Leonore Bovy, Martin Dresler, Richard G M Morris, Guillén Fernández
Knowledge extracted across previous experiences, or schemas, benefit encoding and retention of congruent information. However, they can also reduce specificity and augment memory for semantically related, but false information. A demonstration of the latter is given by the Deese-Roediger-McDermott (DRM) paradigm, where the studying of words that fit a common semantic schema are found to induce false memories for words that are congruent with the given schema, but were not studied. The medial prefrontal cortex (mPFC) has been ascribed the function of leveraging prior knowledge to influence encoding and retrieval, based on imaging and patient studies...
December 24, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28067965/rp-hplc-dad-esi-qtof-ms-based-metabolic-profiling-of-the-potential-olea-europaea-by-product-wood-and-its-comparison-with-leaf-counterpart
#13
Sonda Ammar, Maria Del Mar Contreras, Boutheina Gargouri, Antonio Segura-Carretero, Mohamed Bouaziz
INTRODUCTION: Olea europaea L. organs such as leaves, stems and roots have been associated with numerous in vivo and in vitro biological activities and used for traditional medicinal purposes. However, tree wood is an untapped resource with little information about their chemical composition. OBJECTIVE: That is why, the objective of this study is to increase the knowledge about phytochemicals from 'Chemlali' olive wood by means of mass spectrometry-based analyses...
January 9, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28065542/arsenic-bio-accessibility-and-bioaccumulation-in-aged-pesticide-contaminated-soils-a-multiline-investigation-to-understand-environmental-risk
#14
M S Rahman, A J Reichelt-Brushet, M W Clark, T Farzana, L H Yee
Bio-accessibility and bioavailability of arsenic (As) in historically As-contaminated soils (cattle tick pesticide), and pristine soils were assessed using 3 different approaches. These approaches included human bio-accessibility using an extraction test replicating gastric conditions (in vitro physiologically-based extraction test); an operationally defined bioaccessibility extraction test - 1.0M HCl extraction; and a live organism bioaccumulation test using earthworms. A sequential extraction procedure revealed the soil As-pool that controls bio-accessibility and bioaccumulation of As...
January 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28061872/amoebic-liver-abscess-in-northern-sri-lanka-first-report-of-immunological-and-molecular-confirmation-of-aetiology
#15
Selvam Kannathasan, Arumugam Murugananthan, Thirunavukarasu Kumanan, Devika Iddawala, Nilanthi Renuka de Silva, Nadarajah Rajeshkannan, Rashidul Haque
BACKGROUND: Since 1985, amoebic liver abscess (ALA) has been a public health problem in northern Sri Lanka. Clinicians arrive at a diagnosis based on clinical and ultrasonographic findings, which cannot differentiate pyogenic liver abscess (PLA) from ALA. As the treatment and outcome of the ALA and PLA differs, determining the etiological agent is crucial. METHODS: All clinically diagnosed ALA patients admitted to the Teaching Hospital (TH) in Jaffna during the study period were included and the clinical features, haematological parameters, and ultrasound scanning findings were obtained...
January 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28060086/sex-specific-associations-between-self-reported-sleep-duration-cardiovascular-disease-hypertension-and-mortality-in-an-elderly-population
#16
Anders Broström, Ake Wahlin, Urban Alehagen, Martin Ulander, Peter Johansson
BACKGROUND: Both short and long sleep durations have been associated to increased mortality. Knowledge about sex-specific differences among elderly regarding associations between sleep duration, cardiovascular health, and mortality is sparse. OBJECTIVE: The aims of this study are to examine the association between self-reported sleep duration and mortality and to investigate whether this association is sex specific and/or moderated by cardiovascular morbidity, and also to explore potential mediators of sleep duration effects on mortality...
January 5, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28059697/digital-literacy-knowledge-and-needs-of-pharmacy-staff-a-systematic-review
#17
Katie MacLure, Derek Stewart
OBJECTIVE: To explore the digital literacy knowledge and needs of pharmacy staff including pharmacists, graduate (pre-registration) pharmacists, pharmacy technicians, dispensing assistants and medicine counter assistants. METHODS: A systematic review was conducted following a pre-published protocol. Two reviewers systematically performed the reproducible search, followed by independent screening of titles/abstracts then full papers, before critical appraisal and data extraction...
October 7, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28057875/perceived-challenges-of-working-in-a-fertility-clinic-a-qualitative-analysis-of-work-stressors-and-difficulties-working-with-patients
#18
Jacky Boivin, Laura Bunting, Emily Koert, Chin Ieng U, Christianne Verhaak
STUDY QUESTION: What are some of the challenges of working in a fertility clinic? SUMMARY ANSWER: The most frequently mentioned challenges were workload (e.g. high time pressure) and patient-related sources (e.g. unrealistic expectations). WHAT IS KNOWN ALREADY: One study showed a too high workload, worry about handling human material and low success rates were main stressors in fertility clinics. STUDY DESIGN, SIZE, DURATION: An online open-ended survey inviting participants to respond to seven questions was distributed to 5902 members of the European Society for Human Reproduction and Embryology (ESHRE, October 2010)...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057656/epidemiology-and-control-measures-of-outbreaks-due-to-antibiotic-resistant-organisms-in-europe-embargo-a-systematic-review-protocol
#19
Babu Rajendran Nithya, Beryl Primrose Gladstone, Jesús Rodríguez-Baño, Frangiscos Sifakis, Andreas Voss, Yehuda Carmeli, Francesco Robert Burkert, Panagiota Gkolia, Evelina Tacconelli
INTRODUCTION: Improving our understanding of outbreaks due to antibiotic-resistant bacteria (ARB) and their control is critical in the current public health scenario. The threat of outbreaks due to ARB requires multifaceted efforts. However, a global overview of epidemiological characteristics of outbreaks due to ARB and effective infection control measures is missing. In this paper, we describe the protocol of a systematic review aimed at mapping and characterising the epidemiological aspects of outbreaks due to ARB and infection control measures in European countries...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28057109/-prevalence-of-and-risk-factors-for-delayed-onset-of-lactation-in-chinese-lactating-women-in-2013
#20
S Jiang, Y F Duan, X H Pang, Y Bi, J Wang, L Y Zhao, S A Yin, Z Y Yang
Objective: To study the prevalence of delayed onset of lactation (later than 3 days) in lactating women in China and to analyze its influencing factors. Methods: Data were extracted from Chinese National Nutrition and Health Surveillance-Mothers, from mothers with children under 2 years of age (in 2013). A total of 11 178 women who were lactating or had lactated were selected from 55 counties of 30 provinces (excluding the Tibet Autonomous Region) in China, using the multi-stage stratified cluster randomization sampling method...
December 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
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