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https://www.readbyqxmd.com/read/29352414/transthoracic-echocardiographic-evaluation-of-the-heart-and-great-vessels
#1
REVIEW
André Y Denault, Stéphane Langevin, Martin R Lessard, Jean Francois Courval, Georges Desjardins
PURPOSE: Transthoracic examination of the heart and great vessels is an essential skill that allows the anesthesiologist to evaluate cardiac function. In this article, we describe a pragmatic technique to obtain the essential views to evaluate normal or abnormal cardiac function and to appreciate great vessel anatomy and physiology. PRINCIPAL FINDINGS: The cardiac anatomy and function can be described using standard parasternal, apical, and subcostal views. These windows can also be used to assess the aorta, pulmonary artery, and vena cavae; however, other transthoracic and abdominal windows can be used to complete the evaluation of the great vessels...
January 19, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29349575/parkin-in-parkinson-s-disease-and-cancer-a-double-edged-sword
#2
REVIEW
Khushnuma Wahabi, Ahmad Perwez, Moshahid A Rizvi
Parkin for more than a decade has been portrayed as a neuroprotector gene is now increasingly emerging as a multifaceted gene that can exert entirely opposite effects i.e., both cell proliferation and apoptosis. Parkinson's disease, a neurological disease, progresses due to excess in cell death, while, in case of cancer, cell death normally fails to occur. Parkin, an E3 ubiquitin ligase, was first identified as a gene implicated in autosomal recessive juvenile Parkinsonism, but several evidences indicate that Parkin is a tumor suppressor gene, involved in a variety of cancers...
January 18, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29349038/abnormal-neural-hierarchy-in-processing-of-verbal-information-in-patients-with-schizophrenia
#3
Yulia Lerner, Maya Bleich-Cohen, Shimrit Solnik-Knirsh, Galit Yogev-Seligmann, Tamir Eisenstein, Waheed Madah, Alon Shamir, Talma Hendler, Ilana Kremer
Previous research indicates abnormal comprehension of verbal information in patients with schizophrenia. Yet the neural mechanism underlying the breakdown of verbal information processing in schizophrenia is poorly understood. Imaging studies in healthy populations have shown a network of brain areas involved in hierarchical processing of verbal information over time. Here, we identified critical aspects of this hierarchy, examining patients with schizophrenia. Using functional magnetic resonance imaging, we examined various levels of information comprehension elicited by naturally presented verbal stimuli; from a set of randomly shuffled words to an intact story...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29348409/artificial-selection-for-improved-energy-efficiency-is-reaching-its-limits-in-broiler-chickens
#4
C W Tallentire, I Leinonen, I Kyriazakis
Modern broiler chickens are a major animal husbandry success story, both in terms of efficient resource utilisation and environmental sustainability. However, continuing artificial selection for both efficiency and rapid growth will be subject to both biological limits and animal welfare concerns. Using a novel analytical energy flow modelling approach, we predict how far such selection can go, given the biological limits of bird energy intake and partitioning of energy. We find that the biological potential for further improvements in efficiency, and hence environmental impact reduction, is minimal relative to past progress already made via artificial selection...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29347971/detection-and-dissemination-of-toxoplasma-gondii-in-experimentally-infected-calves-a-single-test-does-not-tell-the-whole-story
#5
Alison Burrells, Alessandra Taroda, Marieke Opsteegh, Gereon Schares, Julio Benavides, Cecile Dam-Deisz, Paul M Bartley, Francesca Chianini, Isabella Villena, Joke van der Giessen, Elisabeth A Innes, Frank Katzer
BACKGROUND: Although the detection of Toxoplasma gondii in bovine tissues is rare, beef might be an important source of human infection. The use of molecular techniques, such as magnetic capture qPCR (MC-qPCR), in combination with the gold standard method for isolating the parasite (mouse bioassay), may increase the sensitivity of T. gondii detection in infected cattle. The risk of transmission of the parasite to humans from undercooked/raw beef is not fully known and further knowledge about the predilection sites of T...
January 18, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29346497/convergent-and-divergent-validity-of-the-grammaticality-and-utterance-length-instrument
#6
Anny Castilla-Earls, Katrina Fulcher-Rood
Purpose: This feasibility study examines the convergent and divergent validity of the Grammaticality and Utterance Length Instrument (GLi), a tool designed to assess the grammaticality and average utterance length of a child's prerecorded story retell. Method: Three raters used the GLi to rate audio-recorded story retells from 100 English-speaking preschool children. To examine convergent validity, the results of the GLi were correlated with 2 language sample measures, mean length of utterance in words and percentage of grammatical utterances, and with the results of the Structured Photographic Expressive Language Test-Third Edition (Dawson, Stout, & Eyer, 2003)...
January 18, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29345727/the-petal-project-an-innovation-in-sexual-healthcare-and-education-for-kenyan-schoolgirl
#7
Karen M Parker
In the western province of Nyanza in Kenya, girls and women face an issue all too common in the developing world-little or no access to affordable means to effectively managing their menstrual flow. As a result, many stay at home or drop out of school because they are teased and embarrassed. Some approach men for money to buy pads and are forced, in return, to engage in transactional sex. The girls may not be able to return to school at all due to pregnancy. The story literally and figuratively continues to cycle, keeping girls in positions of dependency and poverty...
January 18, 2018: Nursing Forum
https://www.readbyqxmd.com/read/29345121/suspected-hypersensitivity-to-cervicovaginal-fluid-what-can-we-learn-from-the-seminal-plasma-allergy-story
#8
F-M Köhn
No abstract text is available yet for this article.
January 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29343283/the-classroom-communication-resource-ccr-intervention-to-change-peer-s-attitudes-towards-children-who-stutter-cws-study-protocol-for-a-randomised-controlled-trial
#9
Rizwana Mallick, Harsha Kathard, Lehana Thabane, Mershen Pillay
BACKGROUND: Children who stutter (CWS) are at a high-risk of being teased and bullied in primary school because of negative peer attitudes and perceptions towards stuttering. There is little evidence to determine if classroom-based interventions are effective in changing peer attitudes towards stuttering. The primary objective is to determine the effect of the Classroom Communication Resource (CCR) intervention versus usual practice, measured using the Stuttering Resource Outcomes Measure (SROM) 6-months post-intervention among grade 7 students...
January 17, 2018: Trials
https://www.readbyqxmd.com/read/29340916/trapped-in-a-tight-spot-scaling-effects-occur-when-according-to-the-action-specific-account-they-should-not-and-fail-to-occur-when-they-should
#10
Elizabeth S Collier, Rebecca Lawson
The action-specific account of perception claims that what we see is perceptually scaled according to our action capacity. However, it has been argued that this account relies on an overly confirmatory research strategy-predicting the presence of, and then finding, an effect (Firestone & Scholl, 2014). A comprehensive approach should also test disconfirmatory predictions, in which no effect is expected. In two experiments, we tested one such prediction based on the action-specific account, namely that scaling effects should occur only when participants intend to act (Witt, Proffitt, & Epstein, 2005)...
January 16, 2018: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29339936/satellite-stories-capturing-professional-experiences-of-academic-health-sciences-librarians-working-in-delocalized-health-sciences-programs
#11
Jackie Phinney, Amanda Rose Horsman
Objective: Health sciences training programs have progressively expanded onto satellite campuses, allowing students the opportunity to learn in communities away from an academic institution's main campus. This expansion has encouraged a new role for librarians to assume, in that a subset of health sciences librarians identify as "satellite librarians" who are permanently located at a distance from the main campus. Due to the unique nature of this role and lack of existing data on the topic, the authors investigated the experiences and perceptions of this unique group of information professionals...
January 2018: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/29339705/a-sad-story-of-a-man-with-two-ventricles
#12
Yavuzer Koza, Uğur Kaya, Hakan Taş, Esma Ateş
No abstract text is available yet for this article.
January 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29339346/user-centered-design-of-learn-to-quit-a-smoking-cessation-smartphone-app-for-people-with-serious-mental-illness
#13
Roger Vilardaga, Javier Rizo, Emily Zeng, Julie A Kientz, Richard Ries, Chad Otis, Kayla Hernandez
BACKGROUND: Smoking rates in the United States have been reduced in the past decades to 15% of the general population. However, up to 88% of people with psychiatric symptoms still smoke, leading to high rates of disease and mortality. Therefore, there is a great need to develop smoking cessation interventions that have adequate levels of usability and can reach this population. OBJECTIVE: The objective of this study was to report the rationale, ideation, design, user research, and final specifications of a novel smoking cessation app for people with serious mental illness (SMI) that will be tested in a feasibility trial...
January 16, 2018: JMIR Serious Games
https://www.readbyqxmd.com/read/29336597/navigating-emotions-and-relationship-dynamics-family-life-review-as-a-clinical-tool-for-older-adults-during-a-relocation-transition-into-an-assisted-living-facility
#14
Kendra A O'Hora, Karen A Roberto
OBJECTIVE: Relocation for the purpose of receiving care may be one of the more challenging transitions for older adults. The purpose of this study was to facilitate a family life review (FLR) session aimed at enhancing family relationships and assisting older adults in coping with the challenges associated with a relocation. METHODS: Fourteen dyads comprised of older adults who relocated to an assisted living facility (ALF) and a chosen family member or friend participated in a FLR session and semi-structured follow up interview...
January 16, 2018: Aging & Mental Health
https://www.readbyqxmd.com/read/29336262/ethosomes-as-novel-vesicular-carrier-an-overview-of-the-principle-preparation-and-its-applications
#15
Sanjoy Kumar Das, Soumalya Chakraborty, Chhandita Roy, Rajan Rajabalaya, Amal Widaad Mohaimin, Jasmina Khanam, Arunabha Nanda, Sheba R David
BACKGROUND: In the study of lipid vesicular carriers in permeation enhancement of drug molecules across skin after the success story of liposomes, ethosomes are a recent addition. There are a number of published reviews but still, there is a lack of reviews representing various aspects in a systematic way with a detailed description of current research works. This review serves to fill this deficiency along with a special emphasize on its preparation methods and application. METHODS: Information was collected from previously published literatures which were represented after analysis in terms of various aspects such as principles, composition, preparation, mechanism of penetration, modified forms, characterization, marketed preparation and its application...
January 15, 2018: Current Drug Delivery
https://www.readbyqxmd.com/read/29335128/-risking-the-encounter
#16
Lionnel Beteille
In their daily practice, psychiatric caregivers seek an encounter with the patient. This involves trying to understand the patient's suffering, to give meaning and to make the clinical connection. This equates to constructing together. Some care organisations are working to create spaces within units which are suited to receiving patients with an atmosphere favouring the encounter. The story of Baptiste illustrates this approach. Testimony.
January 2018: Soins. Psychiatrie
https://www.readbyqxmd.com/read/29334301/navigating-social-distance-in-foundational-clinical-encounters-understanding-medical-students-early-experiences-with-diverse-patients
#17
Miesha Roberts-MacDonald, Saleem Razack
BACKGROUND: Social distance between patients and physicians has been shown to affect the quality of care that patients receive. Little is known about how social distance between students and patients is experienced by learners during early clinical exposures in medical school. OBJECTIVE: This study aims to explore students' stories of experiencing social distance with patients with concordant and discordant social characteristics as themselves, respectively, as well as students' needs from medical curricula regarding developing social competence...
January 15, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29332553/understanding-trauma-normativeness-normalization-and-help-seeking-in-homeless-mothers
#18
Barbara L Brush, Laura E Gultekin, Elizabeth B Dowdell, Denise M Saint Arnault, Katherine Satterfield
Although trauma-informed approaches guide services to families experiencing homelessness, more emphasis is placed on securing housing than addressing underlying trauma contributing to housing instability. Examining the stories of 29 homeless and/or unstably housed mothers within the broader literature on family trauma and violence, chronic illness, and cultural aspects of family functioning, we define the process of trauma normativeness and normalization that may occur with repeated trauma experiences and argue that rehousing efforts must include concomitant attention to trauma and to understanding how individual, family, community, and cultural factors influence help-seeking behaviors in this vulnerable and growing population...
November 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29332528/-killed-out-of-love-a-frame-analysis-of-domestic-violence-coverage-in-hong-kong
#19
Miriam Hernández
A frame analysis was conducted on a Hong Kong newspaper to determine whether news coverage of female fatalities at the hands of their intimate partners was reported in conventional domestic violence ways or if there were culture-specific explanations. Overall, most coverage supported known views of domestic violence, justifying the perpetrator and categorizing the issue as isolated crime. However, a few stories highlighted the historical subordination of women under patriarchy in Confucianism as an important cultural factor...
November 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29332417/-concise-history-of-toxicology-from-empiric-knowledge-to-science
#20
Anna Tompa, Péter Balázs
Toxicology is a science of poisonings by xenobiotics and endogenous physiological changes. Its empiric roots may be traced back to the emerging of the human race because the most important pledge of our predecessors' survival was the differentiation between eatable and poisonous plants and animals. In the course of social evolution, there were three main fields of using poisons: 1) hunting and warfare, 2) to settle social tensions by avoiding military conflicts through hiding strategy of eliminating enemies by toxic substances, 3) medicines applied first as anti-poisons and later by introducing strong substances to defeat diseases, but paradoxically active euthanasia is also a part of the whole story...
January 2018: Orvosi Hetilap
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