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https://www.readbyqxmd.com/read/30100978/a-comparison-of-five-international-clinical-trial-registers-with-the-south-african-register-for-access-to-information-and-usability
#1
Mncengeli Sibanda, Robert Summers, Johanna Catharina Meyer
Introduction: in November, 2005, the South African (SA) National Department of Health (NDoH) mandated that, as from the 1st December, 2005, all new clinical trials to be conducted in the country must be registered on the South African National Clinical Trials Register (SANCTR). The objective was to compare access to the information contained in and the usability of the SANCTR with five other international on-line clinical trials registers. Methods: Access to SANCTR was determined through the use of three search engines using the keywords "South African Clinical Trials...
2018: Pan African Medical Journal
https://www.readbyqxmd.com/read/30083727/effect-of-a-remotely-delivered-tailored-multicomponent-approach-to-enhance-medication-taking-for-patients-with-hyperlipidemia-hypertension-and-diabetes-the-stic2it-cluster-randomized-clinical-trial
#2
Niteesh K Choudhry, Thomas Isaac, Julie C Lauffenburger, Chandrasekar Gopalakrishnan, Marianne Lee, Amy Vachon, Tanya L Iliadis, Whitney Hollands, Sandra Elman, Jacqueline M Kraft, Samrah Naseem, Scott Doheny, Jessica Lee, Julie Barberio, Lajja Patel, Nazleen F Khan, Joshua J Gagne, Cynthia A Jackevicius, Michael A Fischer, Daniel H Solomon, Thomas D Sequist
Importance: Approximately half of patients with chronic conditions are nonadherent to prescribed medications, and interventions have been only modestly effective. Objective: To evaluate the effect of a remotely delivered multicomponent behaviorally tailored intervention on adherence to medications for hyperlipidemia, hypertension, and diabetes. Design, Setting, and Participants: Two-arm pragmatic cluster randomized controlled trial at a multispecialty group practice including participants 18 to 85 years old with suboptimal hyperlipidemia, hypertension, or diabetes disease control, and who were nonadherent to prescribed medications for these conditions...
August 6, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/30071785/hyperinflation-of-nitroprusside
#3
Alex Cobb, Luciana Thornton
Sodium nitroprusside (SNP) is a generically available and rapid-acting intravenous (IV) vasodilator that has been used clinically for decades. Prior to 2013, the cost of SNP was relatively low, and SNP was an affordable option for the treatment of acute hypertension. However, from 2013 to 2017, average wholesale prices for SNP rose to as high as $900 per vial, earning the drug its status as a "hyperinflation drug." Hyperinflation drugs such as SNP pose a significant challenge for pharmacy departments...
August 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/30055892/facilitating-community-partnerships-to-reduce-opioid-overdose-an-engaged-department-initiative
#4
Laura C Palombi, Amy LaRue, Kerry K Fierke
BACKGROUND: The opioid crisis is a major public health priority for most United States communities and requires multi-disciplinary and multi-pronged approaches. Despite this, there is considerable unfulfilled potential for engagement of academic pharmacy with community partners to form mutually-beneficial relationships. OBJECTIVES: This study sought to determine how an opioid-focused Engaged Department Initiative might increase partnerships with rural community members and positively impact faculty teaching, service, practice and research while addressing a critical public health crisis in northern Minnesota...
July 4, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/30044691/cycling-through-migraine-preventive-treatments-implications-for-all-cause-total-direct-costs-and-disease-specific-costs
#5
Janet H Ford, Krista Schroeder, Allen W Nyhuis, Shonda A Foster, Sheena K Aurora
BACKGROUND: Migraine is a common and disabling neurological disease associated with substantial economic burden. Among patients with migraine, it is unknown if cost differences exist when preventive migraine medication (PMM) switches occur. OBJECTIVE: To understand the cost burden and health care resource utilization of patients who discontinue or cycle through 1 (PMM1), 2 (PMM2), or ≥ 3 (PMM3) unique PMM drug classes over a 12-month period versus patients who adhere persistently to their initial PMM class...
July 25, 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/30038439/restructuring-a-pharmacy-department-leadership-strategies-for-managing-organizational-change
#6
BrookeAnne Magrum, Robert J Weber
Background: The Director's Forum series is designed to guide pharmacy leaders in establishing patient-centered services in hospitals and health-systems. This article focuses on leadership strategies for managing organizational change within a pharmacy department. Objective: The goals of this article are to describe the foundations of pharmacy organizational structure changes and strategies to efficiently and effectively manage the associated change. Methods: This article will aim to (1) describe the organizational structure change process, (2) list known rules to follow when redesigning an organizational structure, (3) briefly describe the organizational change at the Ohio State Wexner Medical Center, and (4) describe leadership strategies to overcome potential challenges of organizational changes...
July 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/30037583/the-characteristics-and-outcomes-of-patients-who-make-an-emergency-department-visit-for-hypertension-after-use-of-a-home-or-pharmacy-blood-pressure-device
#7
Clare L Atzema, Alyssa Wong, Sameer Masood, Ayesha Zia, Suad Al-Bulushi, Qazi Z Sohail, Ahmed Cherry, Florence S Chan
STUDY OBJECTIVE: Emergency department (ED) visits for hypertension are rapidly increasing. Hypertension guidelines began recommending use of self-measurement blood pressure (BP) devices in the early 2000s, which could be contributing to the increase. We aim to examine the proportion of ED visits for hypertension that occurred after a BP measurement with a self-measuring device, and the associated outcomes. METHODS: This retrospective observational study included adults who made an ED visit and received a primary diagnosis of hypertension at 1 of 5 community and tertiary hospitals in Ontario, Canada, between April 2010 and March 2011...
July 18, 2018: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/30032475/an-explorer-of-chemical-biology-of-plant-natural-products-in-southwest-china-xiaojiang-hao
#8
REVIEW
Yue-Mao Shen, Duo-Zhi Chen
Xiaojiang Hao, who obtained Master Degree from Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS) in 1985, and Doctor in Pharmacy degree in Pharmacy from Institute for Chemical Research, Kyoto University, in 1990, was born in Chongqing in July, 1951. In 1991, he returned to KIB, CAS, as an Associate professor and served as the chair of the Department of Phytochemistry. In 1994, he was promoted to a full professor at the current institute. He served as the Deputy Director of KIB and the Director of Open Laboratory of Phytochemistry from 1995 to 1997, and the Director of KIB from 1997 to 2005...
July 21, 2018: Natural Products and Bioprospecting
https://www.readbyqxmd.com/read/30031132/potential-strategies-to-achieve-universal-influenza-vaccination-for-children-provider-attitudes-in-two-states
#9
Alison Saville, Peter Szilagyi, Laura Helmkamp, Christina Albertin, Dennis Gurfinkel, Sitaram Vangela, L Miriam Dickinson, Xinkai Zhou, Heather Roth, Allison Kempe
OBJECTIVES: Childhood influenza vaccination rates remain sub-optimal. Provider perceptions on strategies to achieve universal vaccination are needed. We assessed perceptions and attitudes of primary care providers across two states regarding two strategies to potentially bolster rates: Centralized-Reminder/Recall (C-R/R), such as R/R from state immunization registries; and influenza vaccination by complementary community vaccinators (CCV), such as retail pharmacies, schools and health departments...
July 18, 2018: Academic Pediatrics
https://www.readbyqxmd.com/read/30025782/learning-organic-chemistry-day-by-day-the-best-choice-of-the-best-pharmacy-students
#10
Guido Angelini, Carla Gasbarri
BACKGROUND AND PURPOSE: During over ten years of experience in teaching organic chemistry at the Department of Pharmacy we have tried to answer the following question: why do most students tend to take the exam one, two, or more years after the end of the course they have attended? Several reasons could justify this delay, but three seem to be the most common drawbacks for our students: a) time needed for the comprehension of the arguments; b) the number of mandatory exams to pass before organic chemistry; c) lack of a self-evaluation method...
June 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/30025770/student-pharmacist-perceptions-of-participation-in-hands-on-naloxone-counseling
#11
Julie Hines, Erin Deja, Esther P Black
BACKGROUND AND PURPOSE: Opioid overdose is a leading cause of death across the United States. Rho Chi Pharmacy Honor Society students at the University of Kentucky initiated a project to provide fellow students a volunteer opportunity to educate at-risk patients about naloxone using a physician-approved protocol. The goal was to improve student counseling skills by allowing them to apply knowledge learned during didactic and simulated training. EDUCATIONAL ACTIVITY AND SETTING: Third and fourth year pharmacy students at the University of Kentucky voluntarily provided opioid overdose and naloxone counseling to patients at the health department and other locations...
June 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/30024793/spatial-methods-to-enhance-public-health-surveillance-and-resource-deployment-in-the-opioid-epidemic
#12
Zan M Dodson, Eun-Hye Enki Yoo, Christian Martin-Gill, Ronald Roth
OBJECTIVES: To improve public health surveillance and response by using spatial optimization. METHODS: We identified cases of suspected nonfatal opioid overdose events in which naloxone was administered from April 2013 through December 2016 treated by the city of Pittsburgh, Pennsylvania, Bureau of Emergency Medical Services. We used spatial modeling to identify areas hardest hit to spatially optimize naloxone distribution among pharmacies in Pittsburgh. RESULTS: We identified 3182 opioid overdose events with our classification approach, which generated spatial patterns of opioid overdoses within Pittsburgh...
September 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/30022906/a-retrospective-cross-sectional-study-of-antibiotics-prescribing-patterns-in-admitted-patients-at-a-tertiary-care-setting-in-the-ksa
#13
Ahmad Alharafsheh, Mohamed Alsheikh, Sheraz Ali, Amani A Baraiki, Ghadah Alharbi, Tahani Alhabshi, Amina Aboutaleb
Objective: Little is known about the pattern of antibiotics' prescribing for hospitalized adult patients in the Kingdom of Saudi Arabia. This study explored the prescribing practices of antibiotics in a large tertiary care setting serving diverse population. Methods: This retrospective cross-sectional study included 1.666 antibiotic prescriptions prescribed over a period of 3 months (January 2016-March 2016) in an adult inpatient department of King Saud Medical City (KSMC)...
July 2018: International Journal of Health Sciences
https://www.readbyqxmd.com/read/30015531/combining-pharmacy-expertise-with-asthma-educator-certification-assessing-the-impact-on-inner-city-asthma-patients
#14
Teresa George Abraham, Charnicia Huggins, Gilda Diaz-Fuentes, John Roglieri
OBJECTIVE: Asthma is one of the major causes of hospital readmissions in the South Bronx. The goal of this study was to assess the impact of asthma education provided by registered pharmacists with asthma educator certification (AE-C), on medication adherence and hospitalizations/Emergency Department (ED) visits. METHODS: This was a retrospective chart review of patients seen in the pulmonary clinic from October 2014 to August 2015 for asthma education by AE-C pharmacists...
July 17, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30013300/satisfaction-with-medication-reconciliation-completed-by-pharmacy-technicians-in-an-emergency-department
#15
Sajani Patel, A Scott Mathis, Jennifer Costello, Hoytin Lee Ghin, Germin Fahim
Purpose: To survey advanced nurse practitioners, physician assistants, nurses, physicians, and resident physicians involved with collecting and reconciling medication histories in the emergency department (ED) to measure their satisfaction with the current process involving pharmacy technicians. Methods: Two sites within a large health system with pharmacy technician-driven medication reconciliation processes asked health care professionals to complete a survey of 20 multiple-choice questions...
July 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/30013255/where-do-delays-occur-when-women-receive-antenatal-care-a-client-flow-multi-site-study-in-four-health-facilities-in-nigeria
#16
Friday E Okonofua, Rosemary N Ogu, Lorretta F Ntoimo, Mohammed Gana, Ola N Okike, Adetoye Durodola, Hadiza S Galadanci
Objectives: The objective of the study was to identify where delays occur when women present for antenatal care in four Nigerian referral hospitals, and to make recommendations on ways to reduce delays in the course of provision of antenatal care in the hospitals. Design: Prospective observational study. Setting: Four Nigerian (1 tertiary and 3 secondary) Hospitals. Participants: Women who presented for antenatal care...
March 2018: Ghana Medical Journal
https://www.readbyqxmd.com/read/30007301/a-centralized-automated-dispensing-system-in-a-french-teaching-hospital-return-on-investment-and-quality-improvement
#17
Sarah Berdot, Virginie Korb-Savoldelli, Emmanuel Jaccoulet, Vincent Zaugg, Patrice Prognon, Laetitia Minh Maï Lê, Brigitte Sabatier
Objectives: To evaluate the return on investment (ROI) and quality improvement after implementation of a centralized automated-dispensing system after 8 years of use. Design: Prospective evaluation of ROI; before and after study to evaluate dispensing errors; user satisfaction questionnaire after 8 years of use. Setting: The study was conducted at a French teaching hospital in the pharmacy department, which is equipped with decentralized automated medication cabinets in the wards...
July 11, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29976829/prospective-daily-review-of-discharge-medications-by-pharmacists-effects-on-measures-of-safety-and-efficiency
#18
Ryan Craynon, David R Hager, Mike Reed, Julie Pawola, Steve S Rough
PURPOSE: Results of a pilot project to improve the safety and efficiency of the discharge process by adding daily pharmacist review and preparation of discharge medication orders to an existing discharge medication reconciliation workflow are reported. SUMMARY: Due to patient capacity issues, the pharmacy department of a large tertiary medical center implemented changes to the existing medication discharge workflow. A steering committee was established, with subgroups responsible for workflow development, electronic medical record enhancement, and data collection designated...
July 5, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29968639/healthcare-it-strategic-alignment-challenges-and-recommendations
#19
Sahar Alsharif, Nabila Benslimane, Mohamed Khalifa, Colin Price
Information technology (IT) has dramatically transformed business processes in many industries including healthcare, where electronic health records, electronic prescribing and computerized provider order entry systems have positively changed the practice of healthcare. Recently, King Faisal Specialist Hospital and Research Center, Saudi Arabia, implemented various IT systems in multiple clinical and administrative departments leading to major transformation in healthcare workflows and business processes. At the pharmacy department, many Healthcare-IT alignment challenges are still perceived...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29962243/are-uk-hospital-pharmacy-departments-ready-for-the-rise-of-gene-therapy-medicinal-products
#20
Nicola Stoner
The first gene therapy medicines are licensed and National Institute for Health and Care Excellence approved for use in the NHS. UK Hospital pharmacy departments will need to work with multidisciplinary colleagues to ensure that there are facilities available to handle this new group of medicines. Areas Covered: UK licensed and National Institute for Health and Care Excellence gene therapy medicinal products (GTMP) and requirements for handling. Review of pharmacy facilities and implementation of advanced therapy medicinal products (ATMP) in the UK...
August 2018: Expert Opinion on Biological Therapy
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