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https://www.readbyqxmd.com/read/30324565/economic-burden-of-patients-treated-for-higher-risk-myelodysplastic-syndromes-hr-mds-in-routine-clinical-care-in-the-united-states
#1
Jill A Bell, Aaron Galaznik, Marlo Blazer, Huai-Che Shih, Eileen Farrelly, Augustina Ogbonnaya, Michael Eaddy, Robert J Fram, Douglas V Faller
BACKGROUND AND OBJECTIVE: Significant clinical burden is associated with higher-risk myelodysplastic syndromes (HR-MDS); however, the economic burden has not been fully examined. We examined cost of care and healthcare utilization (HCU) in HR-MDS patients engaged in routine care in the United States (US). METHODS: Adult US patients diagnosed with HR-MDS from 1/1/2008 to 10/31/2015 were identified from the Optum database. Patients were followed until death, progression to acute myeloid leukemia (AML), end of enrollment, or end of study (12/31/2015)...
October 15, 2018: PharmacoEconomics Open
https://www.readbyqxmd.com/read/30315512/the-economic-burden-of-pediatric-asthma-in-the-united-states-literature-review-of-current-evidence
#2
REVIEW
Richard Perry, George Braileanu, Thomas Palmer, Paul Stevens
Asthma is a chronic respiratory disease that is widespread throughout the US population and disproportionately affects children. This literature review aimed to identify recent information regarding the economic burden of pediatric asthma in the US. MEDLINE, EMBASE, Econlit, and PsycINFO databases and gray literature sources were searched from January 2012 to January 2018 to capture relevant publications. Publications reporting on healthcare resource utilization and/or healthcare costs of pediatric asthma were included (n = 8)...
October 13, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/30314553/preceptor-perceptions-of-block-scheduling-and-institutional-track-programs-to-prepare-appe-students-for-residency-or-hospital-careers
#3
Meghan Bodenberg, Brooke Linn, Tracy Sprunger, Brian Shepler
INTRODUCTION: Butler University College of Pharmacy and Health Sciences (BUCOPHS) and Purdue University College of Pharmacy (PUCOP) created Block Scheduling and Institutional Track programs with the goal of better preparing students interested in pursuing postgraduate residency and/or a career in institutional practice. While informal feedback has been positive from both students and preceptors, more formalized feedback was sought. The objective of this study was to determine whether preceptors perceived additional benefits in precepting students selected through Block Scheduling and Institutional Track programs compared to students scheduled on rotations through a traditional preference or optimization process...
August 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/30310349/relationship-between-buprenorphine-adherence-and-relapse-health-care-utilization-and-costs-in-privately-and-publicly-insured-patients-with-opioid-use-disorder
#4
Naoko A Ronquest, Tina M Willson, Leslie B Montejano, Vijay R Nadipelli, Bernd A Wollschlaeger
Background: Treatment for opioid use disorder is important because of the negative health, societal and economic consequences of illicit opioid use, but treatment adherence can be a challenge. This study assessed the association between buprenorphine medication-assisted treatment (MAT) adherence and relapse, health care utilization and costs. Patients and methods: Patients with opioid use disorder who were newly initiating a buprenorphine MAT regimen were identified in the 2008-2014 MarketScan® Commercial and Medicaid Databases and followed for 12 months after their earliest outpatient pharmacy claim for buprenorphine...
2018: Substance Abuse and Rehabilitation
https://www.readbyqxmd.com/read/30304353/receipt-of-overlapping-opioid-and-benzodiazepine-prescriptions-among-veterans-dually-enrolled-in-medicare-part-d-and-the-department-of-veterans-affairs-a-cross-sectional-study
#5
Ron Carico, Xinhua Zhao, Carolyn T Thorpe, Joshua M Thorpe, Florentina E Sileanu, John P Cashy, Jennifer A Hale, Maria K Mor, Thomas R Radomski, Leslie R M Hausmann, Julie M Donohue, Katie J Suda, Kevin Stroupe, Joseph T Hanlon, Chester B Good, Michael J Fine, Walid F Gellad
Background: Overlapping use of opioids and benzodiazepines is associated with increased risk for overdose. Veterans receiving medications concurrently from the U.S. Department of Veterans Affairs (VA) and Medicare may be at higher risk for such overlap. Objective: To assess the association between dual use of VA and Medicare drug benefits and receipt of overlapping opioid and benzodiazepine prescriptions. Design: Cross-sectional. Setting: VA and Medicare...
October 9, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/30295883/cost-and-healthcare-utilization-among-non-elderly-head-and-neck-cancer-patients-in-the-military-health-system-a-single-payer-universal-health-care-model
#6
Art Ambrosio, Diana D Jeffery, Laura Hopkins, Harry B Burke
Introduction: Examining costs and utilization in a single-payer universal health care system provides information on fiscal and resource burdens associated with head and neck cancer (HNC). Here, we examine trends in the Department of Defense (DoD) HNC population with respect to: (1) reimbursed annual costs and (2) patterns and predictors of health care utilization in military only, civilian only, and both systems of care (mixed model). Materials and Methods: A retrospective, cross-sectional study was conducted using TRICARE claims data from fiscal years 2007 through 2014 for reimbursement of ambulatory, inpatient, and pharmacy charges...
October 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/30287263/long-term-impact-of-hip-fracture-on-the-use-of-healthcare-resources-a-population-based-study
#7
Jose M Cancio, Emili Vela, Sebastià Santaeugènia, Montse Clèries, Marco Inzitari, Domingo Ruiz
OBJECTIVES: To assess the impact of hip fracture (HF) on health care expenditures and resource use. DESIGN: Observational, retrospective study. An administrative registry was used to obtain sociodemographic, clinical, and expenditure data of patients treated in centers all over Catalonia (North-East Spain). SETTING AND PARTICIPANTS: Male and female patients aged 65 years or older admitted to a Catalonian hospital due to hip fracture (HF) between January 1 2012, and December 31, 2016...
October 1, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/30286166/methodological-considerations-in-clinical-outcomes-assessment-of-pharmacy-based-minor-ailments-management-a-systematic-review
#8
Vibhu Paudyal, Scott Cunningham, Kathrine Gibson Smith, Katie MacLure, Cristin Ryan, Maria Cordina
BACKGROUND: The accessibility of services within community pharmacies provides an ideal opportunity to manage minor ailments, yet over £1.1 billion is spent by the National Health Service (NHS) in the United Kingdom (UK) in managing minor ailments in high cost settings. There is a need to review the evidence base around clinical effectiveness of pharmacy-based management of minor ailments since the absence of such may lead to under-utilisation of pharmacy services and non-implementation of available pharmacy service models...
2018: PloS One
https://www.readbyqxmd.com/read/30282665/development-of-an-operational-productivity-tool-within-a-cancer-treatment-center-pharmacy
#9
Thomas S Achey, Allison R Riffle, Robert M Rose, Marc Earl
PURPOSE: The development and implementation of an operational productivity tool in an academic cancer treatment center are described. SUMMARY: Based on the increasing complexity of care delivery within the oncology setting, solutions were explored within Cleveland Clinic pharmacy's productivity model. Data were electronically captured based on orders processed through the outpatient oncology setting, including hazardous and nonhazardous medications. Based on current workflow, inpatient and outpatient orders were reviewed in productivity metrics...
October 3, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/30266675/asbmt-pharmacy-special-interest-group-survey-on-car-t-cell-therapy-administrative-logistical-and-toxicity-management-practices-in-the-united-states
#10
Zahra Mahmoudjafari, Kelly G Hawks, Angela A Hsieh, Dragos Plesca, Katie S Gatwood, Kathryn A Culos
Administration of immune effector cell (IEC) therapy is a complex endeavor requiring extensive coordination and communication of various health care and administrative teams. Chimeric antigen receptor (CAR) T cells are the most established IEC therapy available. As of July 2018, there are two commercial gene therapy products, tisagenlecleucel and axicabtagene ciloleucel, approved by the United States Food & Drug Administration (FDA). To gain insight into the infrastructure and practices across the country, the American Society of Bone Marrow Transplant (ASBMT) Pharmacy Special Interest Group (SIG) conducted an electronic survey on the current administrative, logistical, and toxicity management practices of CAR T cell therapy across the United States...
September 25, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/30241225/availability-of-who-essential-medicines-for-cancer-treatment-in-botswana
#11
Yehoda M Martei, Sebathu Chiyapo, Surbhi Grover, Doreen Ramogola-Masire, Scott Dryden-Peterson, Lawrence N Shulman, Neo Tapela
PURPOSE: Stock outs of cancer drugs are potentially fatal but have not been systematically studied in low- and middle-income countries. The aim of this study was to determine the availability and alignment of the Botswana National Essential Medicines List (NEML) for cancer drugs with the WHO's Essential Medicines List (EML). METHODS: The availability and cost of cancer drugs were analyzed using data from a weekly stock catalog sent by Botswana's Central Medical Store to all pharmacy departments in government hospitals...
September 2018: Journal of Global Oncology
https://www.readbyqxmd.com/read/30234369/evaluation-of-pharmacy-developed-antibiotic-desensitization-protocols
#12
Xian Jie Cindy Chen, Karen Fong, Diana Altshuler, Yanina Dubrovskaya, Eddie Louie, Nancy Amoroso, Ronald Goldenberg, John Papadopoulos
BACKGROUND: Parameters within reconstitution, storage, stability, and administration may be optimized according to the unique pharmacokinetics of each antibiotic to ensure a successful desensitization. OBJECTIVE: The study aims to evaluate the successfulness and safety of antibiotic desensitization protocols developed by the pharmacy department at our institution. METHODS: A retrospective study was conducted at an 800-bed, urban, tertiary care, academic medical center...
September 20, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/30209006/diagnostic-accuracy-of-a-rapid-telemedicine-encounter-in-the-emergency-department
#13
Joseph A Izzo, Jonathan Watson, Rahul Bhat, Matthew Wilson, Joseph Blumenthal, Christina Houser, Edward Descallar, Daniel Hoffman, Ethan Booker
OBJECTIVES: Emergency Department crowding is an increasing problem, leading to treatment delays and higher risk of mortality. Our institution recently implemented a telemedicine physician intake ("tele-intake") process as a mitigating front-end strategy. Previous studies have focused on ED throughput metrics such as door to disposition; our work aimed to specifically assess the tele-intake model for clinical accuracy. METHODS: We retrospectively reviewed ED visits at a high acuity, tertiary care academic hospital before and after tele-intake implementation...
August 7, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/30199196/proposal-to-reduce-adult-immunization-barriers-in-california
#14
Ozlem Equils, Caitlyn Kellogg, Wendy Berger, Keri Hurley-Kim, Elan Rubinstein, Gerald Kominski
Adult vaccination rates in the United States are consistently lower than the National Healthy People 2020 goals. Barriers to adult vaccination include inconsistency of insurance coverage of adult vaccines and difficulty in accessing vaccines. To help address the gap in adult access to vaccines, in 2016 the Department of Health Care Services--which administers the Medi-Cal program (California’s version of Medicaid)--implemented the All Plan Letter (APL) 16-009, which requires coverage of recommended adult vaccines as a pharmacy benefit...
August 2018: Policy Brief
https://www.readbyqxmd.com/read/30197101/all-cause-mortality-among-people-with-hiv-released-from-an-integrated-system-of-jails-and-prisons-in-connecticut-usa-2007-14-a-retrospective-observational-cohort-study
#15
Kelsey B Loeliger, Frederick L Altice, Maria M Ciarleglio, Katherine M Rich, Divya K Chandra, Colleen Gallagher, Mayur M Desai, Jaimie P Meyer
BACKGROUND: People transitioning from prisons or jails have high mortality, but data are scarce for people with HIV and no studies have integrated data from both criminal justice and community settings. We aimed to assess all-cause mortality in people with HIV released from an integrated system of prisons and jails in Connecticut, USA. METHODS: We linked pharmacy, custodial, death, case management, and HIV surveillance data from Connecticut Departments of Correction and Public Health to create a retrospective cohort of all adults with HIV released from jails and prisons in Connecticut between 2007 and 2014...
September 6, 2018: Lancet HIV
https://www.readbyqxmd.com/read/30196515/cost-evolution-of-biological-agents-for-the-treatment-of-spondyloarthritis-in-a-tertiary-hospital-influential-factors-in-price
#16
Mariángeles González-Fernández, Elena Villamañán, Inmaculada Jiménez-Nácher, Francisco Moreno, Chamaida Plasencia, Francisco Gaya, Alicia Herrero, Alejandro Balsa
Background Spending on biological agents has risen dramatically due to the high cost of the drugs and the increased prevalence of spondyloarthritis. Objective To evaluate the annual cost per patient and cost for each biological drug for treating patients with spondyloarthritis from 2009 to 2016, and to calculate factors that affect treatment cost, such as optimizing therapies by monitoring drug serum levels, the use of biosimilar-TNF inhibitors, and official discounts or negotiated rebates in biologicals acquired by the pharmacy department...
September 8, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/30180774/acceptability-of-naloxone-dispensing-among-pharmacists
#17
Vivian Do, Emily Behar, Caitlin Turner, Michelle Geier, Phillip Coffin
BACKGROUND: The San Francisco Department of Public Health initiated naloxone prescribing at 6 safety net clinics. We evaluated this intervention, demonstrating that naloxone prescribing from primary care clinics is feasible and acceptable. OBJECTIVE: To evaluate acceptability of naloxone dispensing to patients prescribed opioids among pharmacists serving clinics participating in a naloxone intervention. METHODS: We surveyed 58 pharmacists from November 2013 through January 2015 at pharmacies that serviced San Francisco safety net clinics...
September 4, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/30175629/a-youth-friendly-pharmacy-initiative-decreasing-unintended-pregnancies-among-disenfranchised-youth
#18
Calpurnyia B Roberts, Jane Bedell
Teens from neighborhoods that have experienced historical and contemporary disinvestment have among the highest rates of teen pregnancy, yet they have less access to resources to reduce unintended pregnancies. In recognition of this, the New York City Department of Health and Mental Hygiene (NYCDOHMH) developed the Youth-Friendly Pharmacy Initiative. Over 7 consecutive months in 2015, educational materials and free NYCDOHMH condoms were placed strategically in independent pharmacies in the South Bronx. Refills were made monthly...
September 3, 2018: Health Promotion Practice
https://www.readbyqxmd.com/read/30173640/review-of-evidence-on-handling-hazardous-drugs-and-products-in-urology-services-consensus-document-between-the-spanish-urology-association-and-the-spanish-society-of-health-system-pharmacists
#19
Miguel Unda-Urzáiz, Jose María Alonso-Herreros, Jesus Maria Fernández-Gómez, Marisa Gaspar-Carreño, Jose Manuel Cozar-Olmos, Ana Cristina Cercós Lleti
OBJECTIVE: The intravesical administration of hazardous drug products is a  standard practice in the urology setting, which potentially exposing medical  personnel to these drug products. It was deemed necessary to have a consensus document among the scientific societies involved (the Spanish Urological  Association and the Spanish Society of Hospital Pharmacy) that collects the best  available evidence on the safest handling possible of dangerous drug products in the setting of urology departments...
September 1, 2018: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/30172562/-intravenous-lines-in-transfusion-and-their-medical-devices
#20
L Basset, B Lassale, L Succamiele, M Moya-Macchi
Treatment by blood transfusion first requires an intravenous cannula. Professionals remember the optimal diameter for transfusion (16 to 18G). Practices differ according to the department concerned. Neonatology and paediatric wards use precision filters and put in fine cannulas (24G) with the constraint that this restricts transfusion flow rate. In haematology and oncology departments, the state of the patient's veins has to be considered when administering chemotherapy which may be toxic for vascular endothelium and the implantation of a venous port by a critical care anaesthetist may be suggested...
August 14, 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
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