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https://www.readbyqxmd.com/read/30548439/effect-of-h%C3%A2-so%C3%A2-solution-treating-on-the-adhesion-charge-transfer-and-catalytic-performance-of-screen-printed-pedot-pss
#1
Di Xu, Hujiang Shen, Wei Wang, Junjie Xie, Tao Zhang, Huihui Yuan, Yuyu Li, Xinyu Chen, Yunlong He, Yumei Zhang
Post-treatment was performed for poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) films screen-printed on fluorine-doped tin oxide (FTO) substrates, to improve their charge transfer efficiency. Different H₂SO₄ solutions including concentrated H₂SO₄ and H₂SO₄ diluted with H₂O or dimethyl sulfoxide (DMSO) were adopted during the post-treatment. The adhesion of the as-treated films was evaluated by adhesive tape peeling tests, the surface morphology and vertical charge transfer from the films to the substrates were investigated by current-sensing atomic force microscopy, and the catalytic activities toward I₃- reduction of PEDOT:PSS films were characterized via electrochemical measurements...
December 12, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/30543220/a-label-free-aptamer-based-nanogap-capacitive-biosensor-with-greatly-diminished-electrode-polarization-effects
#2
Zahra Ghobaei Namhil, Cordula Kemp, Emanuele Verrelli, Alex Iles, Nicole Pamme, Ali M Adawi, Neil T Kemp
A significant impediment to the use of impedance spectroscopy in bio-sensing is the electrode polarization effect that arises from the movement of free ions to the electrode-solution interface, forming an electrical double layer (EDL). The EDL screens the dielectric response of the bulk and its large capacitance dominates the signal response at low frequency, masking information particularly relevant for biological samples, such as molecular conformation changes and DNA hybridization. The fabrication of nanogap capacitors with electrode separation less than the EDL thickness can significantly reduce electrode polarization effects and provide enormous improvement in sensitivity due to better matching of the sensing volume with the size of the target entities...
December 13, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/30531726/identification-of-homologous-recombination-events-in-mouse-embryonic-stem-cells-using-southern-blotting-and-polymerase-chain-reaction
#3
Dan Zhou, Lei Tan, Jian Li, Tanbin Liu, Yi Hu, Yalan Li, Sachiyo Kawamoto, Chengyu Liu, Shiyin Guo, Aibing Wang
Relative to the issues of off-target effects and the difficulty of inserting a long DNA fragment in the application of designer nucleases for genome editing, embryonic stem (ES) cell-based gene-targeting technology does not have these shortcomings and is widely used to modify animal/mouse genome ranging from large deletions/insertions to single nucleotide substitutions. Notably, identifying the relatively few homologous recombination (HR) events necessary to obtain desired ES clones is a key step, which demands accurate and reliable methods...
November 20, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/30526360/impact-of-digital-mammography-on-cancer-detection-and-recall-rates-11-3-million-screening-episodes-in-the-english-national-health-service-breast-cancer-screening-program
#4
Roger G Blanks, Matthew G Wallis, Rupert Alison, Olive Kearins, Jacquie Jenkins, Julietta Patnick, Rosalind M Given-Wilson
Purpose To report the impact of changing from screen-film mammography to digital mammography (DM) in a large organized national screening program. Materials and Methods A retrospective analysis of prospectively collected annual screening data from 2009-2010 to 2015-2016 for the 80 facilities of the English National Health Service Breast Cancer Screening Program, together with estimates of DM usage for three time periods, enabled the effect of DM to be measured in a study of 11.3 million screening episodes in women aged 45-70 years (mean age, 59 years)...
December 11, 2018: Radiology
https://www.readbyqxmd.com/read/30508626/fatty-acyl-compounds-from-marine-streptomyces-griseoincarnatus-strain-hk12-against-two-major-bio-film-forming-nosocomial-pathogens-an-in-vitro-and-in-silico-approach
#5
Neethu Kamarudheen, K V Bhaskara Rao
The perpetual increase in the resistance offered by biofilm-forming nosocomial pathogens has become a critical clinical challenge. Marine Streptomyces sps present a promising future of novel compounds with novel applications. We focus on the anti-biofilm activity of marine Streptomyces against two major nosocomial pathogens from clinical samples, Pseudomonas aeruginosa and Staphylococcus aureus. Herein, Streptomyces griseoincarnatus, a species known to harbour alkaline protease inhibitors and anti-tumour compounds were found to exhibit anti-biofilm activity...
November 30, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/30507676/extravascular-lung-water-monitoring-for-thoracic-and-lung-transplant-surgeries
#6
Sherif Assaad, Wolf B Kratzert, Albert C Perrino
PURPOSE OF REVIEW: Excessive accumulation of extravascular lung water (EVLW) resulting in pulmonary edema is the most feared complication following thoracic surgery and lung transplant. ICUs have long relied on chest radiography to monitor pulmonary status postoperatively but the increasing recognition of the limitations of bedside plain films has fueled development of newer technologies, which offer earlier detection, quantitative assessments, and can aide in preoperative screening of surgical candidates...
November 29, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/30506830/large-area-organic-solar-cells-material-requirements-modular-designs-and-printing-methods
#7
REVIEW
Guodong Wang, Muhammad Abdullah Adil, Jianqi Zhang, Zhixiang Wei
The printing of large-area organic solar cells (OSCs) has become a frontier for organic electronics and is also regarded as a critical step in their industrial applications. With the rapid progress in the field of OSCs, the highest power conversion efficiency (PCE) for small-area devices is approaching 15%, whereas the PCE for large-area devices has also surpassed 10% in a single cell with an area of ≈1 cm2 . Here, the progress of this fast developing area is reviewed, mainly focusing on: 1) material requirements (materials that are able to form efficient thick active layer films for large-area printing); 2) modular designs (effective designs that can suppress electrical, geometric, optical, and additional losses, leading to a reduction in the PCE of the devices, as a consequence of substrate area expansion); and 3) printing methods (various scalable fabrication techniques that are employed for large-area fabrication, including knife coating, slot-die coating, screen printing, inkjet printing, gravure printing, flexographic printing, pad printing, and brush coating)...
December 3, 2018: Advanced Materials
https://www.readbyqxmd.com/read/30504786/3d-microdevices-that-perform-sample-purification-and-multiplex-qrt-pcr-for-early-cancer-detection-with-confirmation-of-specific-rnas
#8
Yusuke Kimura, Masashi Ikeuchi, Yoshinori Inoue, Koji Ikuta
MicroRNA expression analysis is an important screening tool for the early detection of cancer. In this study, we developed two portable three-dimensional microdevices for multiple singleplex RNA expression analysis by microRNA purification and qRT-PCR as a prototype for point-of-care testing. These microdevices are composed of several types of modules termed 'chemical IC chips'. We successfully reduced the heating area and fluorescence observation area, reduced the energy required for the reaction, and improved the portability of all systems in the devices...
November 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30501047/titanium-dioxide-nanotube-based-oxygen-indicator-for-modified-atmosphere-packaging-efficiency-and-accuracy
#9
Junwei Wen, Shuting Huang, Yu Sun, Zhengjie Chen, Yixiang Wang, Houbin Li, Xinghai Liu
Colorimetric oxygen indicators can be applied for non-destructive testing in packaging; especially in modified atmosphere packaging (MAP). In this paper; titanium dioxide (TiO₂) nanotube; which is used as a semiconductor photocatalyst in oxygen indicators; was synthesized via a microwave-assisted hydrothermal method. X-Ray Diffraction (XRD) was used to analyze its crystal form and Scanning Electron Microscope (SEM).to characterize its morphology. Its properties were studied using Brunauer-Emmett-Teller (BET), Diffuse Reflection Spectrum (DRS), and Bluebottle experiments...
November 29, 2018: Materials
https://www.readbyqxmd.com/read/30499280/-preparation-of-microarray-structured-polymer-film-and-its-effect-on-3d-cell-culture
#10
Weimin Jiang, Weikang Zhang, Dongdong Li, Ye Song
The two-dimensional (2D) cell culture model is currently used to study cellular processes and drug screening for human diseases. However, the growth of cells is affected by many factors. For conventional 2D cell culture, many of the difficulties are encountered in accurately replicating the cell function in three-dimensional (3D) tissues. Compared with 2D cell culture, much attention is paid to the cell-to-cell and cell-matrix interactions for 3D cell culture systems, which can more closely mimic the growth environment for cultured cells...
November 25, 2018: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/30479599/are-medical-laboratories-ready-for-the-diagnosis-of-parasitic-diseases
#11
Ahmet Özbilgin
Economic instability, destabilisation with armed conflagration, religious and ethnic conflicts are the most important driving factors for migrations towards Europe. Mediterranean countries are important route for refugees who emigrate from the Middle East, Africa and Asia. Viral, bacterial, parasitic and fungal diseases carried by these refugees constitute a significant health risk in Mediterranean countries. Parasitic diseases, such as intestinal parasites, pediculosis, scabies, lymphatic filariasis, schistosomiasis, malaria and leishmaniasis, which may reach the Mediterranean region trough migrations, were briefly reviewed and the precautions to be taken were mentioned...
November 2018: EJIFCC
https://www.readbyqxmd.com/read/30473842/enrichment-of-lithium-from-salt-lake-brine-by-forward-osmosis
#12
Jinli Li, Min Wang, Youjing Zhao, Hongjun Yang, Yuan Zhong
Forward osmosis (FO) is a concentration process based on the natural phenomena of osmosis. It is considered a breakthrough technology that can be potentially used for concentrating solutions and suspensions. The diluted nature of brine restricts the treatment technologies that can be applied. Then, brine concentration by FO could represent a new emerging technology enabling the application of a wider range of treatment alternatives. The performance of concentrated brine depending upon FO membranes was studied at normal temperature and pressure in this research...
October 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/30473321/screening-utility-of-a-rapid-non-invasive-dry-eye-assessment-algorithm
#13
Michael T M Wang, Ally L Xue, Jennifer P Craig
PURPOSE: To evaluate the discriminative ability of a rapid non-invasive dry eye assessment algorithm (global evaluation component: SANDE questionnaire, and non-invasive tear film breakup time; subtype classification testing component: tear film lipid layer grade, and tear meniscus height) in detecting dry eye disease, as defined by the TFOS DEWS II diagnostic criteria. METHODS: Two hundred and thirty-five participants (77 male, 158 female), with a mean ± SD age of 43 ± 17 years, were recruited into a prospective diagnostic accuracy study...
November 22, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/30472444/photothermal-effects-induced-by-surface-plasmon-resonance-at-graphene-gold-nanointerfaces-a-multiscale-modeling-study
#14
Jiu Pang, Luqi Tao, Xiaoling Lu, Qun Yang, Vivek Pachauri, Zeping Wang, Sven Ingebrandt, Xianping Chen
Surface plasmon resonance (SPR) biosensors have enormous potential in biological recognitions and biomolecular interactions, especially for the real time measurement of disease diagnosis and drug screening. Extensive efforts have been invested to ameliorate the sensing performances, while the photothermal effects, which are induced by the plasmon resonance, have an obvious impact. However, due to the limitations of experimental approaches, the theoretical mechanisms and specific influences of the SPR sensors with photothermal effects are few researched...
November 6, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/30472220/a-molecularly-imprinted-electrochemical-nanobiosensor-for-prostate-specific-antigen-determination
#15
Z Yazdani, H Yadegari, H Heli
Prostate Specific Antigen (PSA) is a biomarker employed for detection of prostate cancer. An electrochemical nanobiosensor is designed and fabricated using a molecularly imprinted polymer for the simple and fast PSA detection. The imprinted polymer served as a PSA artificial receptor fabricated by electrochemical polymerization of pyrrole on screen-printed gold electrode in the presence of PSA. PSA was a molecular template for the polymer. The fabricated nanobiosensor was evaluated by differential pulse voltammetry and using K3 [Fe(CN)6 ]/K4 [Fe(CN)6 ] as an electrochemical marker...
November 22, 2018: Analytical Biochemistry
https://www.readbyqxmd.com/read/30469979/surface-enhanced-perfect-absorption-in-metamaterials-with-periodic-dielectric-nanostrips-on-silver-film
#16
Meng Qin, Shengxuan Xia, Xiang Zhai, Yu Huang, Lingling Wang, Lei Liao
Integrated dielectric metamaterials with plasmonic structures can cause drastic optical resonances and strengthen the capacity of light absorption. Here, we describe the optical properties of silicon nanoarrays on a thin silver film for extreme light confinement at subwavelength nanoscales. We attain the nearly total absorption in silicon nanostrips, which support magnetic quadruple Mie-type resonances in the visible regions. The Mie resonant field of the dielectric nanostrip engages the screening response of the silver film, resulting in plasmon resonance configuration and thus achieving perfect light absorption in the dielectric nanostrip...
November 12, 2018: Optics Express
https://www.readbyqxmd.com/read/30469499/lectins-at-interfaces-an-atomic-force-microscopy-and-multi-parameter-surface-plasmon-resonance-study
#17
Katrin Niegelhell, Thomas Ganner, Harald Plank, Evelyn Jantscher-Krenn, Stefan Spirk
Lectins are a diverse class of carbohydrate binding proteins with pivotal roles in cell communication and signaling in many (patho)physiologic processes in the human body, making them promising targets in drug development, for instance, in cancer or infectious diseases. Other applications of lectins employ their ability to recognize specific glycan epitopes in biosensors and glycan microarrays. While a lot of research has focused on lectin interaction with specific carbohydrates, the interaction potential of lectins with different types of surfaces has not been addressed extensively...
November 22, 2018: Materials
https://www.readbyqxmd.com/read/30461735/tunable-terahertz-metamaterial-absorber-based-on-dirac-semimetal-films
#18
Tongling Wang, Maoyong Cao, Huiyun Zhang, Yuping Zhang
In this paper, the tunable properties of metamaterial absorbers based on 3D Dirac semimetal films (DSFs) in the terahertz (THz) regime are discussed in theory. We consider the absorbers with square-shaped, circular-patch, and cross-shaped resonators. These resonances are theoretically polarization-insensitive at normal incidence because of their 90° rotational symmetry and can achieve perfect absorption in numerical simulation. We then introduce dual-band and broadband absorbers by combining two DSF-based square-shaped (or circular-patch) resonators into one unit cell with different sizes...
November 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/30452051/nanomodel-visualization-of-fluid-injections-in-tight-formations
#19
Junjie Zhong, Ali Abedini, Lining Xu, Yi Xu, Zhenbang Qi, Farshid Mostowfi, David Sinton
The transport and phase change of a complex fluid mixture under nanoconfinement is of fundamental importance in nanoscience, and limits the recovery efficiency from tight oil reservoirs (<10%). Herein, through experiments and supporting theory we characterize the transport and phase change of a nanoconfined complex fluid mixture. Our nanofluidic platform, nanomodel, replicates shale reservoirs in terms of mean pore size (∼100 nm), permeability (∼μD) and porosity (∼10%). We screen conditions for the most promising shale EOR strategies, directly quantifying their pore-scale efficiency and underlying mechanisms...
November 29, 2018: Nanoscale
https://www.readbyqxmd.com/read/30445806/thermal-treatment-of-aerosol-deposited-nimn%C3%A2-o%C3%A2-ntc-thermistors-for-improved-aging-stability
#20
Michaela Schubert, Christian Münch, Sophie Schuurman, Véronique Poulain, Jaroslaw Kita, Ralf Moos
This paper examines the influence of a short-term thermal treatment of aerosol deposited negative temperature coefficient (NTC) thermistor films on the NTCR characteristics and their long-term stability with different electrode materials. An aerosol deposition of a spinel-based NiMn₂O₄ powder on alumina substrates with screen-printed AgPd and Au interdigital electrode structures was performed. The manufactured components of the typical size of 1206 were tempered in a moderate temperature range of 200 °C to 800 °C and aged for 1000 h at 125 °C in air...
November 15, 2018: Sensors
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