Pavel S Gribanov, Anna N Philippova, Maxim A Topchiy, Dmitry A Lypenko, Artem V Dmitriev, Sergey D Tokarev, Alexander F Smol'yakov, Alexey N Rodionov, Andrey F Asachenko, Sergey N Osipov
An efficient access to the novel 5-(aryl)amino-1,2,3-triazole-containing 2,1,3-benzothiadiazole derivatives has been developed. The method is based on 1,3-dipolar azide-nitrile cycloaddition followed by Buchwald-Hartwig cross-coupling to afford the corresponding N -aryl and N , N -diaryl substituted 5-amino-1,2,3-triazolyl 2,1,3-benzothiadiazoles under NHC-Pd catalysis. The one-pot diarylative Pd-catalyzed heterocyclization opens the straightforward route to triazole-linked carbazole-benzothiadiazole D-A systems...
May 6, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry