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https://www.readbyqxmd.com/read/28943979/a-qualitative-study-on-pharmacists-perception-on-integrating-pharmacists-into-private-general-practitioner-s-clinics-in-malaysia
#1
Pui S Saw, Lisa Nissen, Christopher Freeman, Pei S Wong, Vivienne Mak
BACKGROUND: Private general practitioners in Malaysia largely operates as solo practices - prescribing and supplying medications to patients directly from their clinics, thus posing risk of medication-related problems to consumers. A pharmacy practice reform that integrates pharmacists into primary healthcare clinics can be a potential initiative to promote quality use of medication. This model of care is a novel approach in Malaysia and research in the local context is required, especially from the perspectives of pharmacists...
July 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28940412/the-role-of-pre-operative-imaging-and-double-balloon-enteroscopy-in-the-surgical-management-of-small-bowel-neuroendocrine-tumors-is-it-necessary
#2
Nicholas Manguso, Alexandra Gangi, Jeffrey Johnson, Attiya Harit, Nicholas Nissen, Laith Jamil, Simon Lo, Ashley Wachsman, Andrew Hendifar, Farin Amersi
BACKGROUND AND OBJECTIVES: Pre-operative localization of small bowel neuroendocrine tumors (SBNET) is important for operative planning. The aim was to determine the effectiveness of pre-operative imaging and double-balloon enteroscopy (DBE) in identifying extent of disease. METHODS: Database review identified 85 patients with primary SBNET between 2006 and 2013. Analysis included patients who underwent imaging, endoscopy, and surgery at our institution. RESULTS: Average age was 60...
September 20, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28939631/tnf-blockers-inhibit-spinal-radiographic-progression-in-ankylosing-spondylitis-by-reducing-disease-activity-results-from-the-swiss-clinical-quality-management-cohort
#3
Christoph Molnar, Almut Scherer, Xenofon Baraliakos, Manouk de Hooge, Raphael Micheroli, Pascale Exer, Rudolf O Kissling, Giorgio Tamborrini, Lukas M Wildi, Michael J Nissen, Pascal Zufferey, Jürg Bernhard, Ulrich Weber, Robert B M Landewé, Désirée van der Heijde, Adrian Ciurea
OBJECTIVES: To analyse the impact of tumour necrosis factor inhibitors (TNFis) on spinal radiographic progression in ankylosing spondylitis (AS). METHODS: Patients with AS in the Swiss Clinical Quality Management cohort with up to 10 years of follow-up and radiographic assessments every 2 years were included. Radiographs were scored by two readers according to the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) with known chronology. The relationship between TNFi use before a 2-year radiographic interval and progression within the interval was investigated using binomial generalised estimating equation models with adjustment for potential confounding and multiple imputation of missing values...
September 22, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28931059/whole-genome-sequencing-of-mutants-with-increased-resistance-against-the-two-peptide-bacteriocin-plantaricin-jk-reveals-a-putative-receptor-and-potential-docking-site
#4
Bie Ekblad, Jon Nissen-Meyer, Tom Kristensen
By whole-genome sequencing of resistant mutants, a putative receptor for plantaricin JK, a two-peptide bacteriocin produced by some Lactobacillus plantarum strains, was identified in Lactobacillus plantarum NCFB 965 and Weissella viridescens NCFB 1655. The receptors of the two species had 66% identical amino acid sequences and belong to the amino acid-polyamine-organocation (APC) transporter protein family. The resistant mutants contained point mutations in the protein-encoding gene resulting in either premature stop codons, leading to truncated versions of the protein, or single amino acid substitutions...
2017: PloS One
https://www.readbyqxmd.com/read/28929612/comparison-of-laparoscopic-toupet-and-laparoscopic-nissen-fundoplications-in-neurologically-normal-children
#5
Go Miyano, Masaya Yamoto, Hiromu Miyake, Masakatsu Kaneshiro, Keiichi Morita, Hiroshi Nouso, Mariko Koyama, Manabu Okawada, Takashi Doi, Hiroyuki Koga, Geoffrey J Lane, Koji Fukumoto, Atsuyuki Yamataka, Naoto Urushihara
INTRODUCTION: We compared laparoscopic Toupet fundoplication (LTF) and laparoscopic Nissen fundoplication (LNF) in neurologically normal children. METHODS: Forty neurologically normal children who were followed up for more than 3 years after LTF (n = 22) or LNF (n = 18) were reviewed retrospectively. LTF and LNF were performed between 2006 and 2012. RESULTS: There were no significant differences in gender (LTF, 15 male and 7 female patients; LNF:, 12 male and 6 female patients), mean age at surgery (LTF vs LNF: 2...
September 20, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28929567/neonatal-bcg-vaccination-and-atopic-dermatitis-before-13-months-of-age-a-randomised-clinical-trial
#6
Lisbeth Marianne Thøstesen, Jesper Kjaergaard, Gitte Thybo Pihl, Nina Marie Birk, Thomas Nørrelykke Nissen, Peter Aaby, Aksel Karl Georg Jensen, Annette Wind Olesen, Lone Graff Stensballe, Dorthe Lisbeth Jeppesen, Christine Stabell Benn, Poul-Erik Kofoed
Studies have suggested that Bacillus Calmette-Guérin (BCG) vaccination may reduce the risk of allergic diseases, including atopic dermatitis. The Danish Calmette Study was conducted 2012-2015. Within 7 days of birth new-borns were randomised 1:1 to BCG or no BCG. Exclusion criteria were gestational age <32 weeks, birth weight <1000 g, known immunodeficiency or no Danish-speaking parent. Data were collected through telephone interviews and clinical examinations until 13 months. Clinical atopic dermatitis was diagnosed in 466/2,052 (22...
September 20, 2017: Allergy
https://www.readbyqxmd.com/read/28928334/a-collective-review-of-biological-versus-synthetic-mesh-reinforced-cruroplasty-during-laparoscopic-nissen-fundoplication
#7
REVIEW
P S S Castelijns, J E H Ponten, M C G van de Poll, S W Nienhuijs, J F Smulders
BACKGROUND: Laparoscopic cruroplasty and fundoplication have become the gold standard in the treatment of hiatal hernia and gastro-oesophageal reflux disease (GERD). The use of a mesh-reinforcement of the cruroplasty has been proven effective; although, there is a lack of evidence considering which type of mesh is superior. The aim of this study was to compare recurrence rates after mesh reinforced cruroplasty using biological versus synthetic meshes. METHODS: We performed a systematic review of all clinical trials published between January 2004 and September 2015 describing the application of a mesh in the hiatal hernia repair during Nissen fundoplication for both GERD and hiatal hernia...
September 20, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28928332/quality-of-life-after-nissen-fundoplication-in-patients-with-gastroesophageal-reflux-disease-comparison-between-long-and-short-term-follow-up
#8
P S S Castelijns, J E H Ponten, M C G Vd Poll, N D Bouvy, J F Smulders
INTRODUCTION: Nissen fundoplication is the golden standard for surgical treatment of gastroesophageal reflux disease (GERD). Numerous studies report excellent short-term results. However, data regarding long-term quality of life are lacking. The aim of this study is to investigate the long-term quality of life after Nissen fundoplication in patients with GERD and to compare this with the short-term results. PATIENTS AND METHODS: We retrospectively analysed all patients who underwent laparoscopic Nissen fundoplication for GERD between January 2004 and January 2016...
September 20, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28928194/diagnostic-validity-of-early-onset-obsessive-compulsive-disorder-in-the-danish-psychiatric-central-register-findings-from-a-cohort-sample
#9
Judith Nissen, Shelagh Powell, Susanne V Koch, James J Crowley, Manuel Matthiesen, Dorothy E Grice, Per H Thomsen, E Parner
OBJECTIVES: Employing national registers for research purposes depends on a high diagnostic validity. The aim of the present study was to examine the diagnostic validity of recorded diagnoses of early-onset obsessive-compulsive disorder (OCD) in the Danish Psychiatric Central Register (DPCR). DESIGN: Review of patient journals selected randomly through the DPCR. METHOD: One hundred cases of OCD were randomly selected from DPCR. Using a predefined coding scheme based on the Children's Yale Brown Obsessive Compulsive Scale (CYBOCS), experienced research nurse or child and adolescent psychiatrists assessed each journal to determine the presence/absence of OCD diagnostic criteria...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28927422/proximity-to-vector-breeding-site-and-risk-of-plasmodium-vivax-infection-a-prospective-cohort-study-in-rural-ethiopia
#10
Alexander Nissen, Jackie Cook, Eskindir Loha, Bernt Lindtjørn
BACKGROUND: Despite falling incidence and mortality since the turn of the century, malaria remains an important global health challenge. In the future fight against malaria, greater emphasis will have to be placed on understanding and addressing malaria caused by the Plasmodium vivax parasite. Unfortunately, due to years of neglect and underfunding, there are currently many gaps in knowledge of P. vivax malaria. The aims of the present study were to explore the association between distance to vector breeding site and P...
September 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28923031/positive-mental-health-literacy-development-and-validation-of-a-measure-among-norwegian-adolescents
#11
Hanne Nissen Bjørnsen, Mary Elizabeth Bradley Eilertsen, Regine Ringdal, Geir Arild Espnes, Unni Karin Moksnes
BACKGROUND: Mental health literacy (MHL), or the knowledge and abilities necessary to benefit mental health, is a significant determinant of mental health and has the potential to benefit both individual and public mental health. MHL and its measures have traditionally focused on knowledge and beliefs about mental -ill-health rather than on mental health. No measures of MHL addressing knowledge of good or positive mental health have been identified. AIM: This study aimed to develop and validate an instrument measuring adolescents' knowledge of how to obtain and maintain good mental health and to evaluate the psychometric properties of the instrument...
September 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28918786/-treatment-of-meniscal-pathology
#12
Martin Wyman Rathcke, Martin Lind, Morten Ilum Boesen, Nis Nissen, Anders Ploug Boesen, Bjarne Mygind-Klavsen, Per Hölmich
The menisci play a major role in knee function regarding joint movement, stability, load distribution and load transmission. Injuries to the menisci cause pain, and meniscal tears are a common reason for patient referral. In Denmark, partial meniscectomy increased significantly until 2010, and several studies have questioned the long-term effect of meniscectomy as an overall procedure. A Danish national clinical guideline on knee meniscal pathology was published in May 2016, and this article is a short summary of updated knowledge on meniscal pathology and relevant conclusions from the guideline...
September 18, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28918406/rare-cause-of-colonic-intussusception-in-an-adult
#13
Alexander Nissen, Fia Yi
Colonic intussusception is an uncommon phenomenon in adults. Advanced imaging has facilitated the increase in awareness of this rare disease. When present, the lead point is most often secondary to a malignancy with primary adenocarcinoma being the most frequent cause. Current surgical management involves oncologic resections for this reason. This is a report of the third ever-reported case of colonic intussusception secondary to an angiolipoma and the first in the western hemisphere. We also demonstrate that these masses are amenable to minimally invasive resection for definitive management...
September 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28906412/laparoscopic-nissen-total-versus-anterior-180%C3%A2-fundoplication-for-gastro-esophageal-reflux-disease-a-meta-analysis-and-systematic-review
#14
REVIEW
Xing Du, Ji-Min Wu, Zhi-Wei Hu, Feng Wang, Zhong-Gao Wang, Chao Zhang, Chao Yan, Mei-Ping Chen
BACKGROUND: Laparoscopic Nissen fundoplication (LNF) has been the gold standard for the surgical management of Gastro-esophageal reflux disease (GERD). Laparoscopic anterior 180° fundoplication (180° LAF) is reported to reduce the incidence of postoperative complications while obtaining similar control of reflux. The present meta-analysis was conducted to confirm the value of the 2 techniques. METHODS: PubMed, Medline, Embase, Cochrane Library, Springerlink, and China National Knowledge Infrastructure Platform databases were searched for randomized controlled trials (RCTs) comparing LNF and 180° LAF...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905803/diagnosis-and-treatment-of-gastroesophageal-reflux-disease-complicated-by-barrett-s-esophagus
#15
Andriy Stasyshyn
The aim of the study was to evaluate the effectiveness of a diagnostic and therapeutic algorithm for gastroesophageal reflux disease complicated by Barrett's esophagus in 46 patients. MATERIALS AND METHODS: A diagnostic and therapeutic algorithm for complicated GERD was developed. To describe the changes in the esophagus with reflux esophagitis, the Los Angeles classification was used. Intestinal metaplasia of the epithelium in the lower third of the esophagus was assessed using videoendoscopy, chromoscopy, and biopsy...
August 31, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28894312/-there-s-no-touching-in-pharmacy-training-pharmacists-for-australia-s-first-pharmacist-immunization-pilot
#16
Esther T L Lau, Michelle E Rochin, Megan DelDot, Beverley D Glass, Lisa M Nissen
BACKGROUND: Vaccination is a safe, efficient, and cost-effective means of preventing, controlling, and eradicating many life-threatening infections and diseases. Globally, the World Health Organization estimates that vaccination saves between 2 million and 3 million lives annually. However, low immunization rates are a significant public health concern. Individual factors, along with the vaccination process and system, have been reported as perceived barriers and challenges to immunization...
July 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28893159/ethics-and-quality-care-in-nursing-homes-relatives-experiences
#17
Rita Jakobsen, Gerd Sylvi Sellevold, Veslemøy Egede-Nissen, Venke Sørlie
BACKGROUND: A total of 71,000 people in Norway suffer from some form of dementia in 2013, of whom approximately 30,000 are in nursing homes. Several studies focus on the experiences of those who have close relatives and who are staying in a nursing home. Results show that a greater focus on cooperation between nursing staff and relatives is a central prerequisite for an increased level of care. Benefits of developing systematic collaboration practices include relief for nursing staff, less stress, and greater mutual understanding...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28890996/bacillus-calmette-gu%C3%A3-rin-vaccination-at-birth-and-in-vitro-cytokine-responses-to-non-specific-stimulation-a-randomized-clinical-trial
#18
T N Nissen, N M Birk, B A Blok, R J W Arts, A Andersen, J Kjærgaard, L M Thøstesen, T Hoffmann, D L Jeppesen, S D Nielsen, P-E Kofoed, L G Stensballe, P Aaby, M Ruhwald, M G Netea, C S Benn, O Pryds
Several studies have shown increased in vitro cytokine responses to non-related pathogens after Bacillus Calmette-Guérin (BCG) vaccination. A total of 158 infants (80 BCG administered within 7 days of birth; 78 controls) were bled 4 days post-randomization, and at age 3 and 13 months. Geometric mean concentrations of IL-1β, TNF-α, IL-6 (24 h stimulation) and IFN-γ, IL-10, IL-17, IL-22 (96 h stimulation) in response to in vitro stimulation with RPMI, LPS, PHA, Escherichia coli, Streptococcus pneumoniae, Candida albicans and BCG were compared among BCG vaccinated children and controls...
September 10, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28882768/long-term-outcome-of-laparoscopic-nissen-fundoplication-in-a-regional-hospital-setting
#19
Dimitrios Prassas, Andreas Krieg, Thomas-Marten Rolfs, Franz-Josef Schumacher
BACKGROUND: Laparoscopic Nissen fundoplication is considered to be the standard approach for the surgical treatment of gastroesophageal reflux disease. Various trials have assessed the outcome of the operation performed in high-volume centers, but the existing evidence regarding peripheral, low-volume hospitals is scarce. The purpose of this study is to investigate the late outcome of laparoscopic Nissen fundoplication with regard to symptom control and postoperative quality of life in a community-hospital setting...
September 4, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28875581/european-guideline-for-the-diagnosis-and-treatment-of-insomnia
#20
REVIEW
Dieter Riemann, Chiara Baglioni, Claudio Bassetti, Bjørn Bjorvatn, Leja Dolenc Groselj, Jason G Ellis, Colin A Espie, Diego Garcia-Borreguero, Michaela Gjerstad, Marta Gonçalves, Elisabeth Hertenstein, Markus Jansson-Fröjmark, Poul J Jennum, Damien Leger, Christoph Nissen, Liborio Parrino, Tiina Paunio, Dirk Pevernagie, Johan Verbraecken, Hans-Günter Weeß, Adam Wichniak, Irina Zavalko, Erna S Arnardottir, Oana-Claudia Deleanu, Barbara Strazisar, Marielle Zoetmulder, Kai Spiegelhalder
This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, with the aim of providing clinical recommendations for the management of adult patients with insomnia. The guideline is based on a systematic review of relevant meta-analyses published till June 2016. The target audience for this guideline includes all clinicians involved in the management of insomnia, and the target patient population includes adults with chronic insomnia disorder...
September 5, 2017: Journal of Sleep Research
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