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Katsuya Hirata, Masatoshi Nozaki, Narutaka Mochizuki, Shinya Hirano, Kazuko Wada
OBJECTIVE:  To assess effects of neonatal transport on transient tachypnea of the newborn (TTN) in outborn term neonates. STUDY DESIGN:  This retrospective cohort study included 66 term neonates diagnosed with TTN and transported to the Osaka Women's and Children's Hospital neonatal intensive care unit between January 2003 and March 2018. A multivariate logistic regression analysis identified perinatal and neonatal transport factors associated with adverse short-term outcomes defined as mechanical ventilation >48 hours, continuous positive airway pressure >72 hours, pulmonary hemorrhage, and requirement for inhaled nitric oxide, thoracentesis, or surfactant replacement therapy...
December 14, 2018: American Journal of Perinatology
Nesrine Saad Farrag, Sherehan Adel Abdelsalam, Wafaa Laimon, Abdel-Hady El-Gilany
OBJECTIVE:  Sound breastfeeding (BF) knowledge among health professionals is vital for proper institutional support of BF mothers. This study aims to measure both BF knowledge and self-efficacy (SE) of pediatric nurses in supporting BF and to determine their associated factors. STUDY DESIGN:  A cross-sectional study was conducted in Mansoura University Children's Hospital and Mansoura New General Hospital during the period from January to March 2017. A total of 186 nurses completed a predesigned self-administered questionnaire developed by the investigators to measure BF knowledge and SE in BF counseling...
December 14, 2018: American Journal of Perinatology
Maria A C Wester Trejo, Oliver Floßmann, Kerstin W Westman, Peter Höglund, E Christiaan Hagen, Michael Walsh, Jan A Bruijn, David R W Jayne, Ingeborg M Bajema, Annelies E Berden
Objectives: To determine predictors of renal relapse and end-stage renal failure (ESRF) in patients with ANCA-associated vasculitis. Methods: Data from four European Vasculitis Society randomized controlled trials, conducted roughly simultaneously between 15 March 1995 and 30 September 2002, was pooled to determine predictors of long-term renal outcome. The respective trial inclusion criteria covered the entire spectrum of disease severity. Baseline predictors of time to first renal relapse and time to ESRF were assessed by competing events analysis and Cox proportional hazards regression...
January 1, 2019: Rheumatology
F Ruatta, L Derosa, B Escudier, E Colomba, A Guida, G Baciarello, Y Loriot, K Fizazi, L Albiges
BACKGROUND: Bone metastases (BMs) are associated with significant morbidity and shorter survival in renal cell carcinoma (RCC). Our purpose was to identify prognostic factors for overall survival (OS) in RCC patients with BMs. METHODS: Data from patients with BMs from RCC treated at Gustave Roussy between April 1992 and March 2016 were retrospectively collected. Age, sex, Eastern Cooperative Oncology Group-Performance Status, Memorial Sloan-Kettering Cancer Center (MSKCC) risk groups, histology, number and site of bone lesions, concomitant metastases (presence and sites), therapy for BMs (radical resection or palliative surgery, radiotherapy and other local and systemic treatments) and time from diagnosis to BMs were analysed...
December 11, 2018: European Journal of Cancer
Yoshinori Handa, Yasuhiro Tsutani, Takahiro Mimae, Takuro Tasaki, Yoshihiro Miyata, Morihito Okada
BACKGROUND: As segmentectomy becomes widely used for lung cancer treatment, "complex segmentectomy," which makes several, intricate intersegmental planes, remains controversial because of procedural complexity and risk of increased complications and incurability. Questions remain regarding mortality, morbidity, surgical margin, lymph nodes dissection, and postoperative pulmonary function. We evaluated operative and postoperative outcomes of complex compared to simple segmentectomy...
December 11, 2018: Annals of Thoracic Surgery
Catrin Lewis, Neil P Roberts, Andrew Bethell, Lindsay Robertson, Jonathan I Bisson
BACKGROUND: Therapist-delivered trauma-focused psychological therapies are an effective treatment for post-traumatic stress disorder (PTSD). These have become the accepted first-line treatments for the disorder. Despite the established evidence-base for these therapies, they are not always widely available or accessible. Many barriers limit treatment uptake, such as the limited number of qualified therapists to deliver the interventions, cost, and compliance issues, such as time off work, childcare, and transportation, associated with the need to attend weekly appointments...
December 14, 2018: Cochrane Database of Systematic Reviews
Patou Masika Musumari, Arunrat Tangmunkongvorakul, Kriengkrai Srithanaviboonchai, Teeranee Techasrivichien, S Pilar Suguimoto, Masako Ono-Kihara, Masahiro Kihara
BACKGROUND: Depression and anxiety symptoms are prevalent among university students in both developed and developing settings. Recently, grit, defined as perseverance and passion for long-term goals, has emerged as an indicator of success and well-being. However, the relationship between grit and poor mental health outcomes among university students is largely unknown. The current study investigates the relationship of grit with depression and anxiety among university students in Chiang Mai, Thailand...
2018: PloS One
Ebrahim S Elborgy, Matthew R Starr, Jacek G Kotowski, Jackson E Abou Chehade, Raymond Iezzi
PURPOSE: To report visual and anatomical outcomes after the repair of chronic idiopathic macular holes (MHs) with no face-down positioning. METHODS: We conducted a retrospective review of chronic MH cases of greater than 1-year duration that were repaired through pars plana vitrectomy with broad internal limiting membrane peeling and no face-down positioning between March 2009 and December 2017. There were 18 eyes of 18 patients that met inclusion criteria. Patients with MH duration of less than 1 year and without at least 1 month of follow-up were excluded...
December 6, 2018: Retina
T Wang, S H Qu, H Yuan, L S Ye, L Cui
Objective: To analyze the clinical characteristics of ocular tilt reaction in vestibular neuritis patients and discuss its value to the diagnosis of vestibular neuritis. Method: Thirty-five patients with vestibular neuritis confirmed between January 2016 and March 2018 underwent bedside vestibular function physical examination including nystagmus, head impulse test(HIT),head shaking nystagmus(HSN), ocular tilt reaction(OTR), Romberg sign, Fukuda stepping. All patients underwent head CT scan and brain MRI scan + DWI to exclude bleeding and infarction...
July 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Boye Li, Sisi Shen, Wenmei Zhang, Tingjuan Qi, Qin Hu, Yuan Cheng
<i>Background:</i> Emerging evidence suggests that long non-coding RNAs (lncRNAs) can be used as potential biomarkers for a wide range of cancers. Herein, the prognostic value of lncRNA taurine upregulated gene (TUG1) was analyzed using meta-analysis in different kinds of cancers. <i>Methods:</i> Databases including Cochrane Library, PubMed, and Chinese National Knowledge Infrastructure were searched for epidemiological studies up to March 2018. Hazard ratio (HR) and its 95% confidence interval (CI) were calculated to probe the relationship between TUG1 expression and overall survival of various cancer patients...
October 31, 2018: Clinical Laboratory
M F Vázquez-Alonso, A L Díaz-Avalos
INTRODUCTION: Carpal tunnel syndrome is the most common compression neuropathy of the upper limb, and the release of the median nerve is the surgical treatment that is carried out. There are several surgical techniques used to treat this condition; However, this virtual cavity, which we call the carpal tunnel, undergoes several morphological and dimensional changes, prior to surgery and after surgery using the various techniques that the surgeon has a predilection for. MATERIAL AND METHODS: Observational, prospective and longitudinal study conducted in the period from March to November 2009...
July 2018: Acta Ortopédica Mexicana
T Scott Stroup, Natalie A Bareis, Robert A Rosenheck, Marvin S Swartz, Joseph P McEvoy
OBJECTIVE: To investigate subgroup responses to long-acting injectable (LAI) medications haloperidol decanoate (HD) and paliperidone palmitate (PP) in a randomized controlled trial that found no difference between the treatments on the primary outcome of efficacy failure. METHODS: A Comparison of Long-Acting Injectable Medications for Schizophrenia (ACLAIMS) enrolled 311 participants from March 2011 to July 2013 meeting DSM-IV-TR criteria for diagnoses of schizophrenia or schizoaffective disorder at risk of relapse due to medication nonadherence or substance abuse...
November 27, 2018: Journal of Clinical Psychiatry
Fumiaki Kumagai, Takefumi Suzuki, W Wolfgang Fleischhacker, Norio Yasui-Furukori, Masaru Mimura, Hiroyuki Uchida
OBJECTIVE: Placebo effects remain largely unexplored in clinical trials of long-acting injectable (LAI) antipsychotics for schizophrenia. This study aims to characterize patients showing improvements after placebo injections and to search for criteria for the prediction of subsequent response based on the magnitude of score changes after the first week of treatment. METHODS: Data from 450 patients with schizophrenia (DSM-IV) who received placebo injections in 4 double-blind randomized controlled trials evaluating efficacy of LAI paliperidone palmitate obtained through the Yale University Open Data Access (YODA) project were analyzed...
December 4, 2018: Journal of Clinical Psychiatry
Soham Rej, Nathan Herrmann, Andrea Gruneir, Racquel Jandoc, Eric McArthur, Stephanie Dixon, Amit X Garg
OBJECTIVE: Lithium is an effective treatment for mood disorders, but lithium level and renal monitoring every 3 months is recommended in older patients treated with lithium to prevent serious adverse events. This study examined lithium monitoring practices in a large geriatric cohort. METHODS: This population-based cohort study (N = 11,006) used linked health care administrative databases. Older lithium users (n = 5,503; mean age = 70.6 years) in Ontario, Canada, enrolled between April 1, 2002, and March 31, 2014, were propensity score matched 1:1 to valproate users (n = 5,503)...
November 20, 2018: Journal of Clinical Psychiatry
Sha-Li Wen, Juan Li, An-Ni Wang, Meng-Meng Lv, Hui-Yuan Li, Yan-Fang Lu, Jing-Ping Zhang
AIMS AND OBJECTIVES: To determine the effect of a transtheoretical model (TTM)-based intervention on patients with an ostomy and provide patient-centred, accessible assistance, and dynamic education to improve patient self-management. BACKGROUND: Proper self-management may promote the rehabilitation of patients with an ostomy. TTM-based interventions have resulted in positive health behavioural changes. DESIGN: Randomised controlled trial performed according to the CONSORT guidelines...
December 14, 2018: Journal of Clinical Nursing
Matthew G Parry, Arunan Sujenthiran, Thomas E Cowling, Julie Nossiter, Paul Cathcart, Ajay Aggarwal, Noel W Clarke, Heather Payne, Jan van der Meulen
In many countries, specialist cancer services are centralised to improve outcomes. We explored how centralisation affects the radical treatment of high-risk and locally advanced prostate cancer in the English NHS. 79,085 patients diagnosed with high-risk and locally advanced prostate cancer in England (April 2014 to March 2016) were identified in the National Prostate Cancer Audit database. Poisson models were used to estimate risk ratios (RR) for undergoing radical treatment by whether men were diagnosed at a regional co-ordinating centre ('hub'), for having surgery by the presence of surgical services on-site, and for receiving high dose-rate brachytherapy (HDR-BT) in addition to external beam radiotherapy by its regional availability...
December 14, 2018: International Journal of Cancer. Journal International du Cancer
Makoto Tamura, Shohei Nakano, Takuma Sugahara
OBJECTIVES: In Japan, strong reimbursement pricing control measures for existing medical device products have rendered new medical device reimbursement pricing critical for manufacturers. Few studies have been conducted on this aspect; therefore, this paper (1) clarifies whether evaluation of innovation is appropriate or not and (2), if not, investigates its background. METHODS: In this research, 319 C1/C2 government decisions for new medical devices in the 10 years from April 2008 to March 2018 were analyzed...
December 14, 2018: International Journal of Health Planning and Management
Julina Ongkasuwan, Danielle Devore, Sarah Hollas, Jennifer Yan
OBJECTIVE: Complaints of dysphonia and dysphagia frequently require rigid or flexible laryngoscopy in the office to aid in diagnosis. For young children, flexible laryngoscopy can be uncomfortable and often requires multiple adults to restrain the child. Rigid laryngoscopy does not result in crying but does require patient cooperation; thus, it is used primarily in adults. This project describes our experience using rigid laryngoscopy in a pediatric cohort. METHODS: This was a retrospective chart review of patients at a pediatric voice clinic who underwent laryngoscopy from December 2011 through March 2017...
December 13, 2018: Laryngoscope
Emmanuel Couacy-Hymann, Kouamé V Kouakou, Jenna E Achenbach, Léonce Kouadio, Yao M Koffi, Hugues P Godji, Kouassi E Adjé, Jonas Oulaï, Henri J Pell-Minhiaud, Charles E Lamien
In July 2014, an outbreak of severe hemorrhagic disease in a domestic pig population, was reported in San-Pedro, the second seaport city of Ivory-Coast. Animals of all age groups developed clinical signs consistent with African swine fever (ASF). Tissue and serum samples from dead pigs were sent to the laboratory for diagnostic confirmation and molecular characterization based on the partial B646L (p72), the full E183L (p54) gene and the central variable region of the B602L gene. The PCR results confirmed the outbreak of ASF...
December 12, 2018: Transboundary and Emerging Diseases
Lorna Martin Kasyanju Carrero, Wei-Wei Ma, Hou-Fang Liu, Xu-Feng Yin, Bing-Rong Zhou
Botulinum Toxin Type A is a potent neurotoxin that is produced by a gram-positive bacteria clostridium botulinum. Its utilization in the treatment of various medical condition has expanded over the years in both medical and esthetic uses. It is being preferred by most physicians due to its efficacy and lack of side effects. It can be used as monotherapy or combined therapy. The aim of this review study was to show the role and mechanism of action of Botulinum toxin type A in the treatment and prevention of hypertrophic scars and keloids...
December 12, 2018: Journal of Cosmetic Dermatology
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