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Elsa G Edery, Tim Scase, Caroline Kisielewicz, Marc P Dhumeaux
Various types of endoscopic biopsy forceps have been investigated in dogs. The Multibite (MB) are multiple-bite forceps that collect up to four tissue specimens in a single pass through the endoscope, reducing procedure time. The authors prospectively investigated its clinical utility by comparing procedure times and diagnostic quality of samples obtained with the MB to that of biopsies performed with a single-bite forceps (SB), in 21 dogs with gastrointestinal disorders. When comparing the depth, crush artefacts and diagnostic adequacy of the gastric and duodenal biopsies, there was no significant difference between the MB and SB forceps...
August 16, 2018: Veterinary Record
Jason R Woloski, Deepa Burman, Olumuyiwa Adebona
Patients with suspected bites or skin rashes regularly present to their primary care physician. Common mite infections encountered in the primary care office include scabies, chiggers, grain itch, and allergic responses from dust mites. In fact, scabies is one of the 50 most prevalent diseases worldwide. Bed bugs are also becoming increasingly common, living in dark crevices, such as mattresses, feeding at night, and causing a maculopapular immune mediated allergic skin response in humans. Proper identification of the mite or bed bug is essential to guide treatment and eradication...
September 2018: Primary Care
Waleed Gibreel, Jamison Anne Harvey, James Garrity, Uldis Bite
BACKGROUND: Reconstruction of the lower eyelid represents a unique challenge to the reconstructive surgeon. Studies evaluating the utility of the nasolabial V-Y advancement flap in lower eyelid reconstruction are limited and techniques to optimize outcomes following eyelid reconstruction with this technique are not well described. We seek to evaluate our experience and outcomes with lower eyelid reconstruction using the nasolabial perforator-based V-Y advancement flap. METHODS: After institutional review board approval, medical charts of all patients who underwent lower eyelid reconstruction using the nasolabial perforator-based V-Y advancement flap between February 2013 and October 2017 were reviewed...
August 16, 2018: Annals of Plastic Surgery
Zeynep Büyükbayraktar, Cenk Doruk, Hasan Camcı
In adult patients with severe class II division 2 malocclusion, the ideal treatment option is the orthognathic surgery. However, camouflage therapy is also an acceptable treatment option due to its less traumatic and acceptable esthetic and functional results. In this case report, the camouflage treatment with two maxillary premolar extractions in a 21-year-old female patient who did not accept orthognathic surgery is presented. Acceptable esthetic and functional results were obtained at the end of the treatment...
December 2017: Turkish journal of orthodontics
Merve Göymen, Ayşegül Güleç
Objective: This study aimed to find the relationship between mandibular condyle morphology and dental malocclusion in patients with anterior open bite, deep bite, and normal overbite. Methods: Eighty patients were included in this retrospective study. All patients had skeletal Class II pattern. The initial panoramic radiographs of patients were digitized using a software program, and groups were compared in terms of condylar height, width, area, and perimeter. In addition, changes in the condyle surface shape were detected using the same panoramic radiographs...
December 2017: Turkish journal of orthodontics
Neşe Yoko Gönül, Korkmaz Sayınsu
The clinical examination of an 11.10-year-old girl in permanent dentition showed severe crowding, chewing problems and her right maxillary lateral incisor was in palatal position. The molars were in Class II relationship on both sides. An extraction treatment was planned. Upper second premolars and lower first premolars were extracted. Lower crowding was eliminated using physiological tooth movement called "driftodontics". Slots sized 0.022 inches and self-ligating brackets were used. The patient also used a high-pull headgear for anchorage and vertical control reasons for a short period...
September 2017: Turkish journal of orthodontics
Sonika Agarwal, Nidhi Kaeley, Sushant Khanduri, Nand Kishore
Snakebite is considered as a significant public health problem contributing considerably to morbidity and mortality. A neurotoxic snake bite can present from mild ptosis to complete paralysis with external and internal ophthalmoplegia. Three patients presented in emergency intubated outside with deeply comatose, fixed dilated pupil, and absent doll's eye reflex mimicking as brain dead.
July 2018: Indian Journal of Critical Care Medicine
Thara Maria Joseph, R Ravichandran, S Lylajam, Prasanth Viswabharan, Kavitha Janardhanan, Smitha Rajeev
Background: Prosthesis misfit plays an important role in complications such as occlusal and abutment screw loosening and fracture in implant restorations. Reproducing the intraoral relationship of implants through impression procedures is the first step in achieving an accurate, passively fitting prosthesis to ensure maximum accuracy. Hence, splinting of multiple implants with most accurate material may be a valid option. Context: The results of splinting multiple implants are always inconsistent, and there is limited literature available to compare the accuracy of impression techniques as well as materials...
July 2018: Journal of Indian Prosthodontic Society
Alison Roth, Swamy R Adapa, Min Zhang, Xiangyun Liao, Vishal Saxena, Raaven Goffe, Suzanne Li, Ratawan Ubalee, Gagandeep S Saggu, Zarna R Pala, Shilpi Garg, Silas Davidson, Rays H Y Jiang, John H Adams
Malaria parasites transmitted by mosquito bite are remarkably efficient in establishing human infections. The infection process requires roughly 30 minutes and is highly complex as quiescent sporozoites injected with mosquito saliva must be rapidly activated in the skin, migrate through the body, and infect the liver. This process is poorly understood for Plasmodium vivax due to low infectivity in the in vitro models. To study this skin-to-liver-stage of malaria, we used quantitative bioassays coupled with transcriptomics to evaluate parasite changes linked with mammalian microenvironmental factors...
August 15, 2018: Scientific Reports
Nicole Prendeville, Debbie Sell
OBJECTIVE: To profile the pre- and post-operative feeding difficulties in infants with macroglossia in Beckwith Wiedemann Syndrome (m-BWS) who have had tongue reduction surgery (TRS) and to pilot a bespoke feeding rating scale. DESIGN: Retrospective consecutive case series designed with two pre-operative and one 3-month post-operative feeding assessments. A 4-point Likert-type scale was developed and applied retrospectively to describe the feeding behaviors for liquids, purées, and solids...
August 15, 2018: Cleft Palate-craniofacial Journal
Tânia Carvalho, Sandra Trindade, Sílvia Pimenta, Ana B Santos, Filipa Rijo-Ferreira, Luísa M Figueiredo
African trypanosomiasis is caused by the protozoan parasite Trypanosoma brucei, transmitted between mammals by the bite of a tsetse. It has been recently shown that parasites accumulate in large numbers in various organs and tissues, including the mouse testis. Whether parasites are protected from the immune system in the male reproductive organ or can be transmitted through sexual route remains unknown. Here we show that parasites can be detected by fine needle aspiration cytology of the male reproductive system in mice, and histopathological analysis revealed that T...
August 2018: PLoS Neglected Tropical Diseases
Cassie N Lux, William T N Culp, Matthew S Mellema, Desiree D Rosselli, Chad W Schmiedt, Ameet Singh, April Haynes, Laura E Selmic, Heidi Phillips, Milan Milovancev, Philipp D Mayhew, Dorothy C Brown
OBJECTIVE To determine the most common types of injuries in cats surgically treated for thoracic trauma, complications associated with surgical treatment, and factors associated with mortality rate and evaluate the effectiveness of the animal trauma triage (ATT) scoring system for predicting outcome. DESIGN Retrospective case series with nested observational study. ANIMALS 23 client-owned cats surgically treated for thoracic trauma at 7 veterinary teaching hospitals between 1990 and 2014. PROCEDURES Medical records were reviewed to collect data on signalment, medical history, clinical signs and physical examination findings at initial evaluation, clinicopathologic findings, initial emergency treatments and diagnostic tests performed, type of trauma sustained, imaging findings, surgery details, postoperative complications, duration of hospitalization, and cause of death, if applicable...
September 1, 2018: Journal of the American Veterinary Medical Association
Abaineh D Endalew, Igor Morozov, A Sally Davis, Natasha N Gaudreault, Kerstin Wernike, Bhupinder Bawa, Mark G Ruder, Barbara S Drolet, D Scott McVey, Vinay Shivanna, Wenjun Ma, Bonto Faburay, William C Wilson, Juergen A Richt
Schmallenberg virus (SBV) is an orthobunyavirus in the Simbu serogroup that emerged in Germany in late 2011 and was mostly associated with a mild transient disease of sheep and cattle. SBV is transmitted by biting midges (Culicoides species) and causes abortions, stillbirths, and congenital defects in naïve pregnant ruminants. Two separate studies were conducted with a primary objective of better understanding the virological and serological responses of sheep and cattle to different SBV isolates after experimental infection...
August 15, 2018: Vector Borne and Zoonotic Diseases
Pattreeya Tungcharoen, Chatchai Wattanapiromsakul, Pimpimon Tansakul, Seikou Nakamura, Hisashi Matsuda, Supinya Tewtrakul
Curcuma zedoaroides, a Zingiberaceae species, has been used for snake bite antidote and wound care in Thailand. Seven compounds were isolated from the bioactive chloroform extract consisted of one new guaiane sesquiterpene lactone, 5-epiphaeocaulisin A (4) and one new diarylheptanoid, 1,2,3,5-tetrahydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl) heptane (7), together with five known guaiane-type sesquiterpene lactones including gweicurculactone (1), zedoalactone B (2), phaeocaulisin C (3), zedoalactone H (5), and zedoalactone E (6)...
August 15, 2018: Phytotherapy Research: PTR
Natacha Sertour, Violaine Cotté, Martine Garnier, Laurence Malandrin, Elisabeth Ferquel, Valérie Choumet
Borrelia burgdorferi sl is a complex of pathogen bacteria transmitted to the host by Ixodes ticks. European Ixodes ricinus ticks transmit different B. burgdorferi species, pathogenic to human. Bacteria are principally present in unfed tick midgut, then migrate to salivary glands during blood meal and infect a new host via saliva. In this study, efficiency of transmission in a mouse model of three pathogen species belonging to the B. burgdorferi sl complex, B. burgdorferi sensu stricto (B31, N40, and BRE-13), B...
2018: Frontiers in Microbiology
Nathalie Amvongo-Adjia, Emmanuela L Wirsiy, Jacob M Riveron, Winston P Chounna Ndongmo, Peter A Enyong, Flobert Njiokou, Charles S Wondji, Samuel Wanji
BACKGROUND: The epidemiological profiles of vector-borne diseases, such as malaria, are strongly associated with landscape components. The reduction of malaria burden in endemic and epidemic regions mainly depends on knowledge of the malaria-transmitting mosquito species, populations and behavioural characteristics, as well as malaria exposure risks. This work aimed at carrying out a holistic study in order to characterise Anopheles species in relation to human malaria in seven wetlands along the lower section of the volcanic chain of Cameroon...
August 14, 2018: Parasites & Vectors
Stuart D Blacksell, Matthew T Robinson, Paul N Newton, Nicholas P J Day
This study examined the literature on laboratory-acquired infections (LAIs) associated with scrub typhus (Orientia tsutsugamushi) and murine typhus (Rickettsia typhi) research to provide an evidence base for biosafety and biocontainment. Scrub typhus LAIs were documented in 25 individuals, from 1931-2000 with 8 (32%) deaths during the pre-antibiotic era. There were 35 murine typhus LAI reports and no deaths. Results indicated that highest risk activities were working with infectious laboratory animals involving significant aerosol exposures, accidental self-inoculation or bite related infections...
August 10, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Maya Gopalakrishnan, Kolar Vishwanath Vinod, Tarun Kumar Dutta, Kusha Kumar Shaha, Magadi Gopalakrishna Sridhar, Suman Saurabh
Background: Viper envenomation contributes to nearly 50% of snake-bite deaths in India, chiefly due to circulatory shock. The mechanisms leading to circulatory shock include bleeding, capillary leak syndrome (CLS) and myocardial depression. Pituitary-adrenal axis involvement in circulatory shock, though described, has not been fully elucidated. Aims: To identify predictors of circulatory shock and mortality in viper envenomation and explore the role of pituitary-adrenal axis in circulatory shock...
August 13, 2018: QJM: Monthly Journal of the Association of Physicians
Anil K Madugundu, Babylakshmi Muthusamy, Sreelakshmi K Sreenivasamurthy, Chandra Bhavani, Jyoti Sharma, Bankatesh Kumar, Krishna R Murthy, Raju Ravikumar, Akhilesh Pandey
Next-generation sequencing approaches have revolutionized genomic medicine and enabled rapid diagnosis for several diseases. These approaches are widely used for pathogen detection in several infectious diseases. Lyme disease is a tick-borne infectious disease, which affects multiple organs. The causative organism is a spirochete, Borrelia burgdorferi, which is transmitted by ticks. Lyme disease can be treated easily if detected early, but its diagnosis is often delayed or is incorrect leading to a chronic debilitating condition...
August 2018: Omics: a Journal of Integrative Biology
Leng Wei Khoo, Siew Audrey Kow, Ming Tatt Lee, Chin Ping Tan, Khozirah Shaari, Chau Ling Tham, Faridah Abas
Clinacanthus nutans (Burm.f.) Lindau (Acanthaceae), commonly known as Sabah snake grass, is a vegetable and a well-known herb that is considered an alternative medicine for insect bites, skin rashes, herpes infection, inflammation, and cancer and for health benefits. Current review aims to provide a well-tabulated repository of the phytochemical screening, identification and quantification, and the pharmacological information of C. nutans according to the experimental design and the plant preparation methods which make it outstanding compared to existing reviews...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
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