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https://www.readbyqxmd.com/read/29034833/drug-therapy-for-abdominal-aortic-aneurysms-utilizing-omega-3-unsaturated-fatty-acids-and-their-derivatives
#1
Daisuke Akagi, Katsuyuki Hoshina, Toshiaki Watanabe, Micheal S Conte
Abdominal aortic aneurysms (AAA) are life-threatening because of the potential for rupture, resulting in death. The current standard treatment for AAA is surgery, comprising laparotomic graft replacement and endovascular repair. However, because surgery carries the risk of major complications and re-intervention, medical therapies are desirable because they may reduce the occurrence of enlargement and rupture. Recent research shows that the progression of AAA is related to inflammatory reactions, especially those in the NF-kB pathway...
October 13, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/29034780/mortality-in-endovascular-and-open-abdominal-aneurysm-repair-trends-in-germany
#2
Olga von Beckerath, Sebastian Schrader, Marcus Katoh, Bernd Luther, Frans Santosa, Knut Kröger
BACKGROUND: We analysed trends in mortality of endovascular (EVAR) and open aortic repair (OAR) in patients hospitalized for abdominal aortic aneurysms (AAA) in Germany from 2005 to 2015. PATIENTS AND METHODS: We used national statistics published by the Federal Statistical Office in Germany to calculate mortality rate of patients hospitalized with ruptured (rAAA, n = 2,448 in 2005, n = 2,180 in 2015) and non-ruptured (iAAA, n = 11,626 in 2005, n = 14,205 in 2015) AAA...
October 16, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29034042/description-of-the-surgical-strategy-used-for-the-treatment-of-a-complex-disease-report-of-a-case
#3
Kazuki Kihara, Miwa Tashiro, Kohei Miyashita, Masaki Yamamoto, Hironobu Hirose, Takashi Fukutomi, Hideaki Nishimori, Kazumasa Orihashi
We report a rare case in which a patient required three surgeries with competing priorities. In a 68-year-old man diagnosed with an abdominal aortic aneurysm (AAA), computed tomography (CT) revealed an infrarenal AAA, unusual thickening of the sigmoid colon that suggested cancer, and a filling defect in the left atrium. We considered the disease stage, which affects prognosis, and the risk of complications that could interfere with the treatment of the other pathologies and developed a three-stage surgical strategy: (i) endovascular aortic repair, (ii) sigmoid colectomy, and (iii) resection of the left atrial mass...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29034037/characteristics-of-abdominal-aortic-aneurysm-in-japanese-patients-aged-50-years-or-younger
#4
Mitsunori Nakano, Naoyuki Kimura, Harunobu Matsumoto, Tomoyasu Hirano, Koichi Adachi, Koichi Yuri, Atsushi Yamaguchi, Hideo Adachi
Objective: We investigated the characteristics and surgical outcomes of abdominal aortic aneurysm (AAA), which typically occurs in elderly persons, in Japanese patients aged 50 years or younger. Materials and Methods: Clinical records of 999 patients who underwent open or endovascular repair for AAA at our hospital between 2007 and 2015 were reviewed to identify the clinical characteristics and surgical outcomes of young patients with AAA. The cohort included 14 patients aged 50 years or younger (mean, 40.4 years; young group) and 985 patients aged older than 50 years (mean, 72...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29034025/replacement-of-the-thoracoabdominal-aorta-after-endovascular-abdominal-aneurysm-repair-for-ruptured-infected-aneurysm-a-case-report
#5
Nobuo Kondo, Kentaro Tamura, Taichi Sakaguchi, Genta Chikazawa, Hidenori Yoshitaka
A 73-year-old man underwent emergency endovascular abdominal aneurysm repair (EVAR) for a ruptured infected abdominal aortic aneurysm. Two years after EVAR, he was admitted with a spiking fever and left lower back pain. Computed tomography scan revealed not only recurrent graft infection with psoas abscess but also infection around the orifice of the superior mesenteric artery. Because conservative medical therapy with antibiotics could not control the infection, we performed complete removal of the infected stent graft, debridement of psoas abscess, and in situ replacement of the thoracoabdominal aorta using rifampicin-soaked prosthetic grafts, followed by the omental flap...
March 24, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29034019/hybrid-repair-of-an-abdominal-aortic-aneurysm-debranching-with-endovascular-aneurysm-repair-in-a-patient-with-horseshoe-kidney
#6
Keiwa Kin, Hiroshi Takano, Takaya Nakagawa, Yukitoshi Shirakawa
Abdominal aortic aneurysm (AAA) with associated horseshoe kidney (HSK) poses a technical challenge when performing conventional open surgical repair because of possible complications including renal infarction, neuralgia, and collecting system disruption. Endovascular aortic repair (EVAR) is considered the first-line treatment for this pathology, allowing for aneurysm repair without isthmus bisection. However, whether to sacrifice commonly presenting aberrant renal arteries during EVAR is a point of controversy...
March 24, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29034016/improved-outcomes-for-ruptured-abdominal-aortic-aneurysms-using-integrated-management-involving-endovascular-clamping-endovascular-replacement-and-open-abdominal-decompression
#7
Chikashi Aoki, Norihiro Kondo, Yoshiaki Saito, Satoshi Taniguchi, Wakako Fukuda, Kazuyuki Daitoku, Ikuo Fukuda
Objective: Endovascular repair has become the treatment of choice for ruptured abdominal aortic aneurysms (RAAAs). To improve surgical outcomes, preoperative management is important. In 2011, we introduced integrated management, which involves endovascular aneurysm repair, stabilization of hemodynamics by endovascular clamping, and open abdominal decompression to address abdominal compartment syndrome (ACS). Methods: To evaluate the efficacy of this management strategy, 62 patients who had undergone emergency surgery for an RAAA were analyzed retrospectively: group A (n=39), where an old strategy was used, and group B (n=23), where integrated management was introduced...
March 24, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033336/open-abdomen-therapy-with-vacuum-and-mesh-mediated-fascial-traction-after-aortic-repair-an-international-multicentre-study
#8
Stefan Acosta, Arne Seternes, Maarit Venermo, Leena Vikatmaa, Karl Sörelius, Anders Wanhainen, Mats Svensson, Khatereh Djavani, Martin Björck
OBJECTIVES: Open abdomen therapy may be necessary to prevent or treat abdominal compartment syndrome (ACS). The aim of the study was to analyse the primary delayed fascial closure (PDFC) rate and complications after open abdomen therapy with vacuum and mesh mediated fascial traction (VACM) after aortic repair and to compare outcomes between those treated with open abdomen after primary versus secondary operation. METHODS: This was a retrospective cohort, multicentre study in Sweden, Finland, and Norway, including consecutive patients treated with open abdomen and VACM after aortic repair at six vascular centres in 2006-2015...
October 12, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29029952/survival-disparity-following-abdominal-aortic-aneurysm-repair-highlights-inequality-in-ethnic-and-socio-economic-status
#9
Manar Khashram, Suzanne Pitama, Jonathan A Williman, Gregory T Jones, Justin A Roake
OBJECTIVES: Socio-economic status (SES) and ethnicity have been reported as markers influencing the likelihood of increased mortality. The aim of this study was to investigate how SES and ethnicity impacted patient survival after abdominal aortic aneurysm (AAA) repair. METHODS: Consecutive patients undergoing open and endovascular AAA repair during a 14.5 year period were identified. Ethnicity was defined as recorded on health records and SES (a score of 10, where 1 is least deprived and 10 being most deprived) and was linked to census data...
October 10, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29029880/open-versus-endovascular-repair-of-ruptured-abdominal-aortic-aneurysms-what-have-we-learned-after-more-than-2%C3%A2-decades-of-ruptured-endovascular-aneurysm-repair
#10
William P Robinson
BACKGROUND: Ruptured abdominal aortic aneurysm is one of the most difficult clinical problems in surgical practice, with extraordinarily high morbidity and mortality. During the past 23 years, the literature has become replete with reports regarding ruptured endovascular aneurysm repair. METHODS: A variety of study designs and databases have been utilized to compare ruptured endovascular aneurysm repair and open surgical repair for ruptured abdominal aortic aneurysm and studies of various designs from different databases have yielded vastly different conclusions...
October 10, 2017: Surgery
https://www.readbyqxmd.com/read/29022854/single-center-mid-term-experience-with-chimney-graft-technique-for-the-preservation-of-flow-to-the-supra-aortic-branches
#11
Robert Shahverdyan, Spyridon Mylonas, Michael Gawenda, Jan Brunkwall
Objectives To investigate the feasibility and the mid-term outcomes of the chimney-graft technique for the revascularization of supra-aortic branches in patients with thoracic aortic pathologies involving the aortic arch. Methods A retrospective analysis of a prospectively maintained database between January 2010 and July 2016 was performed. Primary endpoints were 30-day and overall mortality. Secondary endpoints were technical success, target vessel patency, stroke/transitory ischemic attack and type I/III endoleak rate...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28983674/contrast-enhanced-ultrasound-ceus-of-the-abdominal-vasculature
#12
REVIEW
Vasileios Rafailidis, Cheng Fang, Gibran T Yusuf, Dean Y Huang, Paul S Sidhu
Vascular diseases account for a significant proportion of abdominal pathology and represent a common referral source for abdominal ultrasonographic examinations. B-mode, color Doppler, and spectral Doppler analyses are well-established in the evaluation of abdominal blood vessels although they may occasionally be limited by lower sensitivity for slow flow visualization or the deeper location of abdominal vascular structures. The introduction of microbubbles as ultrasonographic contrast agents has rendered contrast-enhanced ultrasound (CEUS), a valuable complementary ultrasonographic technique, which is capable of addressing clinically significant problems and guiding patient management...
October 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28965890/estimating-the-error-of-ct-based-measurements-of-aortic-lumen-volume-used-in-endovascular-planning
#13
A England, R K Fisher, R G McWilliams, F Torella
INTRODUCTION: Planning of endovascular sealing of abdominal aortic aneurysms requires measurement of the aortic lumen volume. The aim of this study was to investigate mathematically the effect of intra- and inter-observer variability error, as well as cardiac cycle-related variability, on these measurements. METHODS: Mean (±2SD) intra- and inter-observer error in lumen measurements and mean (+2SD) cardiac cycle-related variability were obtained from published literature and added to the measurement of the flow lumen volume of a 57 mm abdominal aortic aneurysm to calculate average and extreme error possibilities...
November 2017: Radiography
https://www.readbyqxmd.com/read/28964619/a-registry-based-rationale-for-discrete-intervention-thresholds-for-open-and-endovascular-elective-abdominal-aortic-aneurysm-repair-in-female-patients
#14
Stephanie M Tomee, Niki Lijftogt, Anco Vahl, Jaap F Hamming, Jan H N Lindeman
OBJECTIVE: An evidence-based consensus for a female-specific intervention threshold for abdominal aortic aneurysms (AAAs) is missing. This study aims to analyze sex-related differences in the epidemiology of ruptured AAA to establish an intervention threshold for women. METHODS: The Dutch Surgical Aneurysm Audit (DSAA) is a compulsory, nation-wide registry of AAA repairs in The Netherlands. All patients with emergency or elective AAA repair between January 1, 2013, and December 31, 2015, were included in the analysis...
September 27, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28964618/long-term-fate-of-renal-function-after-open-surgery-for-juxtarenal-and-pararenal-aortic-aneurysm
#15
Masayuki Sugimoto, Noriko Takahashi, Kiyoaki Niimi, Akio Kodama, Hiroshi Banno, Kimihiro Komori
BACKGROUND: Although the indications for endovascular aneurysm repair for abdominal aortic aneurysm have been expanding, our primary strategy for pararenal and juxtarenal abdominal aortic aneurysm (P/JRAA) is open surgery (OS). One consequence of OS for P/JRAA is transient renal ischemia owing to renal artery clamping, which can be followed by acute kidney injury (AKI). Prior studies referred to the impact of renal ischemia on AKI, but they have rarely evaluated longer-term renal function...
September 27, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28956729/the-use-of-thoracic-stent-grafts-for-endovascular-repair-of-abdominal-aortic-aneurysms
#16
V P Bastiaenen, Mgj Snoeijs, Jgam Blomjous, J Bosma, V J Leijdekkers, R C van Nieuwenhuizen, A C Vahl
Objectives Stent grafts for endovascular repair of infrarenal aneurysms are commercially available for aortic necks up to 32 mm in diameter. The aim of this study was to evaluate the feasibility of endovascular repair with large thoracic stent grafts in the infrarenal position to obtain adequate proximal seal in wider necks. Methods All patients who underwent endovascular aneurysm repair using thoracic stent grafts with diameters greater than 36 mm between 2012 and 2016 were included. Follow-up consisted of CT angiography after six weeks and annual duplex thereafter...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28955702/aorto-uni-iliac-stent-grafting-and-femoro-femoral-bypass-in-a-patient-with-a-failed-and-catastrophic-endovascular-aortic-aneurysm-repair
#17
Wonho Kim, Min Suk Choi, Jin Ho Choi
A 78-year-old man presented at Eulji University Hospital due to an abdominal aortic aneurysm with maximum diameter of 52 mm, which had been increased from 45 mm over 6 months. He underwent embolization of the left internal iliac artery with vascular plug, prior to endovascular abdominal aortic repair with a bifurcated stent graft system. Unfortunately, the inserted vascular plug was maldeployed and protruded into left external iliac artery, and caused acute limb ischemia. Because revascularization of the occluded segment was failed, emergent hybrid approach with aorto-uni-iliac stent grafting and femoro-femoral bypass was done, successfully...
September 2017: Vascular Specialist International
https://www.readbyqxmd.com/read/28954946/aneurysm-wall-enhancement-detected-by-contrast-computed-tomography-scan-is-associated-with-aneurysm-shrinkage-after-endovascular-aneurysm-repair-for-abdominal-aortic-aneurysm
#18
Eisaku Ito, Naoki Toya, Soichiro Fukushima, Yuri Murakami, Tadashi Akiba, Takao Ohki
BACKGROUND: Aneurysm expansion, and consequent endoleaks, after endovascular aneurysm repair (EVAR) is a major problem. Accurate prediction of aneurysm expansion is demanding for surgeons and remains difficult.Methods and Results:We retrospectively analyzed 157 cases of EVAR for abdominal aortic aneurysm (AAA) using a bifurcated main-body stent-graft. There were 62 cases of aneurysm shrinkage after EVAR, 63 cases of stable aneurysm, and 32 cases of aneurysm expansion. Type I endoleaks were significantly increased in the aneurysm expansion group (EXP) compared with the stable (STB) and shrinkage (SHR) groups (EXP: 15...
September 27, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28951156/black-patients-present-with-more-severe-vascular-disease-and-a-greater-burden-of-risk-factors-than-white-patients-at-time-of-major-vascular-intervention
#19
Peter A Soden, Sara L Zettervall, Sarah E Deery, Kakra Hughes, Michael C Stoner, Philip P Goodney, Ageliki G Vouyouka, Marc L Schermerhorn
BACKGROUND: Although many studies have demonstrated racial disparities after major vascular surgery, few have identified the reasons for these disparities, and those that did often lacked clinical granularity. Therefore, our aim was to evaluate differences in initial vascular intervention between black and white patients. METHODS: We identified black and white patients' initial carotid, abdominal aortic aneurysm (AAA), and infrainguinal peripheral artery disease (PAD) interventions in the Vascular Quality Initiative (VQI) registry from 2009 to 2014...
September 23, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28948856/preliminary-dual-center-experience-with-the-bolton-treovance-endograft
#20
Arron Thind, Dhruv Sarma, Abdel Kader Allouni, Feras Abdallah, David Murray, Kiran Thind, Chris Darby, Ashok Handa, Ed Sideso, Rafiuddin Patel, Mark Bratby, Raman Uberoi
PURPOSE: To present the performance and safety of the Treovance stent graft for endovascular aortic aneurysm repair in a "real-world" patient cohort. METHODS: Patients from 2 centers, deemed unfit for open repair, were electively treated with the Treovance endograft. Clinical preoperative, operative, and up to 1-year postoperative follow-up data of patients were retrospectively analyzed. RESULTS: This study included 46 patients with abdominal aortic aneurysm (44 male), mean age of 78 years ± 8 standard deviation (SD; range: 58-93 years)...
January 1, 2017: Vascular and Endovascular Surgery
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