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https://www.readbyqxmd.com/read/30551891/-sweet-s-syndrome-induced-by-pegfilgrastim-during-a-myelodysplastic-syndrome-areb2-a-case-report
#1
S Nelis, M-A Azerad, A Drowart, P Lewalle, A Efira
INTRODUCTION: Sweet's syndrome is an acute neutrophilic dermatosis characterized by abrupt onset of skin lesions accompanied by fever, arthralgia, leukocytosis and diffuse neutrophilic infiltration of the dermis, as well as an excellent response to corticosteroid therapy. CASE REPORT: A 46-year-old patient with myelodysplastic syndrome was admitted for chemotherapy. On the eighth day of chemotherapy, he received a single dose of pegfilgrastim. Three days later, he developed pyrexia, conjunctivitis, arthralgia and erythematous and painful papulo-nodular lesions...
December 11, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/30550593/reproducibility-of-quantitative-coronary-computed-tomography-angiography-in-asymptomatic-individuals-and-patients-with-acute-chest-pain
#2
Martina C de Knegt, Morten Haugen, Jesper J Linde, Jørgen Tobias Kühl, Børge G Nordestgaard, Lars V Køber, Jens D Hove, Klaus F Kofoed
PURPOSE: Quantitative computed tomography (QCT) provides important prognostic information of coronary atherosclerosis. We investigated intraobserver and interobserver QCT reproducibility in asymptomatic individuals, patients with acute chest pain without acute coronary syndrome (ACS), and patients with acute chest pain and ACS. METHODS: Fifty patients from each cohort, scanned between 01/02/2010-14/11/2013 and matched according to age and gender, were retrospectively assessed for inclusion...
2018: PloS One
https://www.readbyqxmd.com/read/30547871/-christmas-article-when-the-hearth-leads-the-way
#3
Maria Renée Nybro Jansson, Philip Mørkeberg Nilsson
Situs inversus is a medical condition with transposition of the organs in chest and abdomen. The condition may cause misdiagnosis due to inverted location of the origin of acute abdominal pain in cases of e.g. acute appendicitis. In this case report, the condition was first found on a CT scan for urolithiasis. It was also visible on a previously performed X-ray of the patient's chest, where both the apex of the patient's heart and the apex of a jewelry heart were located to the patient's right side. If this is not a unique incident, we propose this finding to be named "goldsmith's sign"...
December 10, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/30545698/coronary-artery-embolism-two-case-reports-and-a-review-of-the-literature
#4
REVIEW
Philip S Vendittelli, Bassent Botros, Howard S Rosman, Viren Govindaraju, Anwar Zaitoun, Tariq S Marroush
Coronary embolism (CE) is an uncommon and unique cause of acute myocardial infarction. In this report, we review 216 cases of CE including 2 new cases from our institution. The mean patient age was 52.5 years and 62% of the patients were males. Chest pain was the most common presenting symptom followed by dyspnea, and the most commonly affected vessel was the left anterior descending artery. Leading etiologies of the embolus were atrial fibrillation, septic emboli, and iatrogenic causes. Treatment approaches varied with thrombus aspiration being used in 30% of cases...
November 10, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30544434/perforation-of-small-intestine-secondary-to-metastatic-lung-adenocarcinoma-a-case-report
#5
Jian Wang, Yimeng Chen, Sisi Zhang, Qingyong Chen
RATIONALE: About 50% of patients with a diagnosis of nonsmall cell lung carcinoma exhibit metastatic disease at the time of diagnosis. The preferential sites of extrapulmonary spread are the lymph nodes, liver, brain, adrenal glands, and bones; gastrointestinal tract perforation secondary to metastatic lung cancer is extremely rare. PATIENT CONCERNS: A 60-year-old male nonsmoker patient presented with a 20-day history of facial, neck, and right upper limb edema...
December 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30542386/the-expression-level-of-mir-155-in-plasma-and-peripheral-blood-mononuclear-cells-in-coronary-artery-disease-patients-and-the-associations-of-these-levels-with-the-apoptosis-rate-of-peripheral-blood-mononuclear-cells
#6
Duo Zhao, Jing Zhao, Jiangbin Sun, Yanling Su, Jinfeng Jian, Huaan Ye, Jiawang Lin, Zongda Yang, Jiatao Feng, Zhiping Wang
The aim of the study was to investigate the expression of miR-155 in plasma and peripheral blood mononuclear cells (PBMCs), the effects of miR-155 on the apoptosis rate of PBMCs and the extent of coronary stenosis in coronary artery disease patients. Seventy chest pain patients were divided into three groups by symptoms, signs, auxiliary examination and coronary arteriography: 21 cases in the acute myocardial infarction group (AMI), 23 cases in the Angor pectoris group (AP) and 26 cases in the control group (CT)...
December 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/30539378/evaluation-of-the-proximal-coronary-arteries-in-suspected-pulmonary-embolism-diagnostic-images-in-51-of-patients-using-non-gated-dual-source-ct-pulmonary-angiography
#7
David M Thomas, Patrick D McLaughlin, James P Nugent, Sarah A Barrett, John R Mayo, Ana-Maria Bilawich, Graham C Wong, Savvas Nicolaou
PURPOSE: This retrospective study reports the frequency and severity of coronary artery motion on dual-source high-pitch (DSHP), conventional pitch single-source (SS), and dual-source dual-energy (DE) CT pulmonary angiography (CTPA) studies. METHODS: Two hundred eighty-eight consecutive patients underwent CTPA scans for suspected pulmonary embolism between September 1, 2013 and January 31, 2014. One hundred ninety-four at DSHP scans, 57 SS scans, and 37 DE scans were analyzed...
December 12, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/30538861/hypertension-is-an-independent-predictor-of-multivessel-coronary-artery-disease-in-young-adults-with-acute-coronary-syndrome
#8
Junhua Ge, Jian Li, Haichu Yu, Bo Hou
Background: Risk factors of multivessel coronary artery disease (CAD) among young acute coronary syndrome (ACS) patients remain elusive now. Methods: This retrospective study analyzed data from 187 consecutive young (age ≤45 years) ACS patients (75 STEMI, 30 NSTEMI, and 72 unstable angina) hospitalized in our hospital from January 2012 to December 2016. Thirty-six young male patients with normal coronary angiography (CAG) findings (no-CAD), who underwent CAG due to suspected chest pain in this period, served as control group...
2018: International Journal of Hypertension
https://www.readbyqxmd.com/read/30538785/combined-use-of-high-sensitive-cardiac-troponin-copeptin-and-the-modified-heart-score-for-rapid-evaluation-of-chest-pain-patients
#9
Beata Morawiec, Brygida Przywara-Chowaniec, Piotr Muzyk, Mariusz Opara, Lam Ho, Lui Chun Tat, Olivier Muller, Ewa Nowalany-Kozielska, Damian Kawecki
Background: Clinical short-term risk stratification is a recommended approach in patients with chest pain and possible acute myocardial infarction (AMI) to further improve high safety of biomarker-based rule-out algorithms. The study aim was to assess clinical performance of baseline concentrations of high-sensitivity cardiac troponin T (hs-TnT) and copeptin and the modified HEART score (mHS) in early presenters to the emergency department with chest pain. Methods: This cohort study included patients with chest pain with onset maximum of 6 h before admission and no persistent ST-segment elevation on electrocardiogram...
2018: Disease Markers
https://www.readbyqxmd.com/read/30533943/coronary-air-embolism-during-coronary-angiography-a-systematic-review
#10
Pramod Theetha Kariyanna, Amog Jayarangaiah, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D Marmur, Syed Haseeb, Teresa Song, Navneet Singh, Samy I McFarlane
Coronary air embolism (CARE) is a rare complication during transluminal coronary angiography or angioplasty and is almost always iatrogenic. CARE can cause significant morbidity and mortality as shown in animal studies. CARE is known to cause acute chest pain, hypotension, bradycardia, ST-segment elevation myocardial infarction (STEMI), and death. Multiple isolated case reports of CARE have been reported. We here present a systematic review of cases of CARE during transluminal coronary angiography or angioplasty...
2018: SciFed journal of cardiology
https://www.readbyqxmd.com/read/30533227/-first-in-man-case-report-of-selective-c-reactive-protein-apheresis-in-a-patient-with-acute-st-segment-elevation-myocardial-infarction
#11
Wolfgang Ries, Ahmed Sheriff, Franz Heigl, Oliver Zimmermann, Christoph D Garlichs, Jan Torzewski
C-reactive protein (CRP) may be causative in cardiovascular disease. As yet, no specific CRP inhibitor for human application has been described. A 69-year-old male was referred with ST segment elevation myocardial infarction (STEMI). Typical symptoms of chest pain started at 10.00 p.m. The patient was admitted to the hospital at 1.30 a.m. the next day. As ECG showed anterior wall myocardial infarction, the patient was immediately transferred to successful emergency angioplasty/drug-eluting- (DE-) stenting of the subtotally occluded left anterior descending artery...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/30532117/-los-niveles-de-mediadores-prorresolutivos-no-corresponden-con-los-de-mediadores-inflamatorios-en-enfermedades-isqu%C3%A3-micas-coronarias
#12
Rashidi Springall-Del Villar, Jorge Arturo Ortega-Hernández, Luis Fernando Pérez, Fausto Sánchez-Muñoz, Julio César Arana Martínez, Héctor González-Pacheco, Rafael Bojalil
Background: Inflammation can be grouped into three phases: proinflammatory, anti-inflammatory, and resolution. The latter, mainly attributed to lipid mediators, is the most recently described, and has been studied little in coronary ischemic diseases. Objective: To evaluate 1) if acute coronary syndromes (ACS) manifest different circulating levels of resolution mediators compared with stable angina (SA); 2) if their concentrations are related to those of pro and anti-inflammatory mediators; and 3) if such concentrations are associated with the severity of the disease and the damage produced...
2018: Gaceta Médica de México
https://www.readbyqxmd.com/read/30529930/sex-differences-in-management-and-outcomes-of-patients-with-stable-symptoms-suggestive-of-coronary-artery-disease-insights-from-the-promise-trial
#13
Neha J Pagidipati, Adrian Coles, Kshipra Hemal, Kerry L Lee, Rowena J Dolor, Patricia A Pellikka, Daniel B Mark, Manesh R Patel, Sheldon E Litwin, Melissa A Daubert, Svati H Shah, Udo Hoffmann, Pamela S Douglas
BACKGROUND: Although sex differences exist in the management of acute coronary syndromes, less is known about the management and outcomes of women and men with suspected coronary artery disease being evaluated with noninvasive testing (NIT). METHODS: We investigated sex-based differences in NIT results and subsequent clinical management in 4,720 women and 4,246 men randomized to CT angiography versus stress testing in the PROMISE trial. Logistic regression models assessed relationships between sex and referral for catheterization, revascularization, and aspirin or statin use...
November 9, 2018: American Heart Journal
https://www.readbyqxmd.com/read/30526522/takotsubo-syndrome-with-pulmonary-embolism-a-case-report-and-literature-review
#14
Qi Jin, Qin Luo, Zhihui Zhao, Qing Zhao, Xue Yu, Lu Yan, Liu Gao, Zhihong Liu
BACKGROUND: Takotsubo syndrome (TTS) is an acute cardiac condition with reversible heart failure which is often triggered by psychological and physical stressful events. Although pulmonary embolism (PE) was reported as a trigger for TTS, the concurrence of TTS and PE has been rarely reported, let alone that triggered by PE. Here we describe a case of a postmenopausal female presenting with symptoms similar to myocardial ischemia, which may be caused by PE, and review the available literature that may help clinicians with their practice to similar situations since no published guidelines are available...
December 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/30526509/novel-variants-in-the-acta2-and-myh11-genes-in-a-cypriot-family-with-thoracic-aortic-aneurysms-a-case-report
#15
Anna Keravnou, Evy Bashiardes, Kyriaki Michailidou, Marinos Soteriou, Areti Moushi, Marios Cariolou
BACKGROUND: Thoracic aortic aneurysm (TAA) and/or thoracic aortic aneurysm and dissection (TAAD) is characterized by a considerable risk of morbidity and mortality of affected individuals. It is inherited in an autosomal dominant pattern and the 20% of patients with non-syndromic TAA have a positive family history. To date, the genetic basis of Cypriot patients with TAA has not been investigated. The purpose of this case report is to determine underlying genetic cause in this Cypriot family with TAA...
December 7, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/30526488/a-new-technique-to-salvage-myocardium-following-the-failure-of-thrombus-aspiration-in-acute-myocardial-infarction-a-case-report
#16
Daoyuan Si, Guohui Liu, Yaliang Tong, Cheng Zhang, Yuquan He
BACKGROUND: The failure of aspiration thrombectomy may negatively impact outcomes in patients with acute myocardial infarction (AMI), but the available options are limited. CASE PRESENTATION: A 41-year-old man with chest pain for 2 h presented with ST-segment elevation myocardial infarction. Coronary angiography revealed a large filling defect extending from the distal left main (LM) coronary artery into the proximal left circumflex (LCX) coronary artery. The whole thrombus moved and occluded the proximal left anterior descending (LAD) artery, while the guidewire crossed the lesion...
December 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/30526257/the-transtelephonic-electrocardiogram-based-triage-is-an-independent-predictor-of-decreased-hospital-mortality-in-patients-with-st-segment-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention
#17
Gyorgy Papai, Gabor Csato, Ildiko Racz, Gabor Szabo, Tamas Barany, Agnes Racz, Miklos Szokol, Balazs Sarman, Istvan F Edes, Daniel Czuriga, Rudolf Kolozsvari, Istvan Edes
INTRODUCTION: The transtelephonic electrocardiogram has been shown to have a great value in the management of out-of-hospital chest pain emergencies. In our previous study it not only improved the pre-hospital medical therapy and time to intervention, but also the in-hospital mortality in ST-segment elevation myocardial infarction. It was hypothesised that the higher in-hospital survival rate could be due to improved transtelephonic electrocardiogram-based pre-hospital management (electrocardiogram interpretation and teleconsultation) and consequently, better coronary perfusion of patients at the time of hospital admission...
December 10, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/30513315/surgical-correction-of-takayasu-s-arteritis-involving-both-coronary-and-pulmonary-arteries
#18
Hee Jung Kim, Hyun Jong Lee, Jae Suk Yoo, Dong Jin Kim, Kwang Lee Cho
We describe a patient presenting acute heart failure due to obliteration of the bilateral coronary arteries and pulmonary arteries with Takayasu's arteritis undergoing surgical correction. The diseased vessels provoked chest pain and severe dyspnea. Urgent surgical correction successfully resolved heart failure by coronary artery bypass graft using bilateral in situ internal thoracic arteries and by patch winding of the left pulmonary artery. Surgical relieving obliterated vessels with Takayasu' arteritis is an effective therapy for a patient presenting severe heart failure...
December 1, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/30509187/management-of-acute-coronary-syndrome-in-emergency-departments-a-cross-sectional-multicenter-study-tunisia
#19
Asma Sriha Belguith, Kaouthar Beltaief, Mohamed Amine Msolli, Wahid Bouida, Hela Abroug, Manel Ben Fredj, Imen Zemni, Mohamed Habib Grissa, Hamdi Boubaker, Mohamed Hsairi, Samir Nouira
BACKGROUND: We aimed to describe diagnosed acute coronary syndrome (ACS) and its care management and outcomes in emergency departments (EDs) and to determine related cardiovascular risk factors (CVRFs). METHODS: We conducted a cross sectional multicenter study that included 1173 adults admitted to EDs for acute chest pain (ACP) in 2015 at 14 sites in Tunisia. Data included patients' baseline characteristics, diagnosis, treatment and output. RESULTS: ACS represented 49...
December 3, 2018: BMC Emergency Medicine
https://www.readbyqxmd.com/read/30503299/a-silent-myocardial-infarction-with-normal-coronary-arteries-associated-with-graves-disease
#20
Chunyu Li, Fuqiong Chen, Xuefeng Yu, Shuhong Hu, Shiying Shao
Acute myocardial infarction (AMI) is a scarce but fatal complication in Graves' disease (GD). Silent myocardial infarction (MI) associated with GD has never been reported. A 37-year-old male patient was admitted due to poorly controlled hyperthyroidism and persistent fever. But the patient did not complain of chest pain on admission. The electrocardiogram (ECG) showed Q waves and ST-segment elevations. Cardiac troponin I (cTnI) was sharply increased. He was qualified to an emergency coronary angiography which showed normal coronary arteries without any stenosis...
November 28, 2018: Heart & Lung: the Journal of Critical Care
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