Juliana O'Reilly, Kikumi D Ono-Moore, Sree V Chintapalli, Jennifer M Rutkowsky, Todd Tolentino, K C Kent Lloyd, I Mark Olfert, Sean H Adams
Skeletal muscle anatomy and physiology are sexually dimorphic but molecular underpinnings and muscle-specificity are not well-established. Variances in metabolic health, fitness level, sedentary behavior, genetics, and age make it difficult to discern inherent sex effects in humans. Therefore, mice under well-controlled conditions were used to determine female and male (n = 19/sex) skeletal muscle fiber type/size and capillarity in superficial and deep gastrocnemius (GA-s, GA-d), soleus (SOL), extensor digitorum longus (EDL), and plantaris (PLT), and transcriptome patterns were also determined (GA, SOL)...
September 2021: Physiological Reports