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https://www.readbyqxmd.com/read/30315287/pancreatic-cancer-following-acute-pancreatitis-a-population-based-matched-cohort-study
#1
Omid Sadr-Azodi, Viktor Oskarsson, Andrea Discacciati, Per Videhult, Johan Askling, Anders Ekbom
BACKGROUND: Acute pancreatitis is linked to pancreatic cancer, but the direction of this association is not fully elaborated. METHODS: This was a population-based cohort study including all Swedish residents diagnosed with a first-time episode of acute pancreatitis between 1997 and 2013 and corresponding matched pancreatitis-free individuals from the general population. Hazard ratios for the association between acute pancreatitis and pancreatic cancer were estimated using multivariable Cox regression models...
October 12, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/30314949/biliary-stone-disease-in-patients-receiving-somatostatin-analogs-for-neuroendocrine-neoplasms-a-retrospective-observational-study
#2
Nicole Brighi, Giuseppe Lamberti, Ilaria Maggio, Lisa Manuzzi, Claudio Ricci, Riccardo Casadei, Donatella Santini, Cristina Mosconi, Andrea Lisotti, Valentina Ambrosini, Maria Abbondanza Pantaleo, Davide Campana
BACKGROUND: Somatostatin analogs are the backbone of neuroendocrine neoplasms treatment. Biliary stone disease is a potentially severe adverse event of somatostatin analogs: an increased incidence has been reported in somatostatin analogs-treated acromegalic patients, but studies on patients with neuroendocrine neoplasms are lacking. AIMS: To evaluate biliary stone disease incidence and associated factors in a large series of patients treated with somatostatin analogs for neuroendocrine neoplasms...
September 24, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/30312404/diet-quality-scores-and-the-risk-of-symptomatic-gallstone-disease-a-prospective-cohort-study-of-male-us-health-professionals
#3
Janine Wirth, Mingyang Song, Teresa T Fung, Amit D Joshi, Fred K Tabung, Andrew T Chan, Cornelia Weikert, Michael Leitzmann, Walter C Willett, Edward Giovannucci, Kana Wu
Objective: To investigate the association between three diet-quality scores corresponding to adherence to healthy dietary patterns [alternate Mediterranean (aMed), Alternate Healthy Eating Index (AHEI-2010), Dietary Approaches to Stop Hypertension (DASH)] and the risk of symptomatic gallstone disease. Methods: The study comprised 43 635 men of the Health Professionals Follow-up Study-an ongoing prospective cohort study of US health professionals. Participants were free of symptomatic gallstone disease and diabetes and provided dietary information every 4 years from 1986 (baseline) until 2012...
October 11, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/30310714/double-pouched-sigmoid-gallbladder-that-can-cause-a-diagnostic-dilemma-to-radiologists-a-case-report
#4
Satheesha B Nayak, Ashwini P Aithal, Abhinitha Padavinangadi, Gayathri Prabhu
Gallbladder shows frequent variations in position, shape, interior, and its duct system. These variations may go unnoticed lifelong; however, they may predispose it for cholecystitis and cholelithiasis. We observed a double pouched gallbladder in an adult male cadaver. The gallbladder was folded to have a sigmoid shape. It had two broad pouches: anterior and posterior and a narrow isthmus in between. Its anterior pouch was covered by peritoneum, whereas the posterior pouch was covered by extrahepatic connective tissue...
September 2018: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/30310644/a-case-of-type-ii-mirizzi-syndrome-treated-by-simple-endoscopic-means
#5
Fu Ho Victor Cheung, Chi Chuen Clarence Mak, Wai Yin Chu, Ning Fan, Ka Wing Lui
Mirizzi syndrome is an uncommon complication of chronic cholelithiasis. Advancement in radiological modalities and minimally invasive surgery has led to improved pre-operative diagnoses and more laparoscopic cholecystectomies. But for unsuitable surgical candidates, endoscopy can be the definitive treatment. In this case, we present a 67-year-old man with type II Mirizzi syndrome treated by simple endoscopic means.
October 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/30310412/protective-effects-of-yinchenhao-decoction-on-cholesterol-gallstone-in-mice-fed-a-lithogenic-diet-by-regulating-lxr-cyp7a1-cyp7b1-and-hmgcr-pathways
#6
Yong Meng, Ke Meng, Xin Zhao, Donghua Li, Qiaoying Gao, Shangwei Wu, Yunfeng Cui
The study attempted to elucidate whether lipid genes are closely associated with lipid metabolic abnormalities during the lithogenic time and how Yinchenhao Decoction (YCHD) works on the transcriptions of lipid genes against cholesterol gallstone model. C57BL/6J mice fed on lithogenic diet (LD) were used for model establishment and randomized into 5 groups. All groups received LD for different weeks with isometrically intragastric administration of YCHD or NS. Biochemical tests were measured and liver tissues were harvested for histological and genetic detection...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/30309092/crow-s-feet-appearance-fissured-gallstones
#7
Hao Xiang, Jason Han, William E Ridley, Lloyd J Ridley
No abstract text is available yet for this article.
October 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/30308423/stone-in-the-distal-jejunum-presenting-as-small-bowel-obstruction-a-case-report
#8
Nafeesah Fatimah, Abubaker Shafiq Ahmed, Muhammad Umar Warraich, Usman Ismat Butt, Qamar Ashfaq Ahmad, Mahmood Ayyaz
INTRODUCTION: Gallstone ileus is a rare presentation of cholelithiasis accounting for around 4% of cases of small bowel obstruction under 65 years of age but rises to 25% in those more than 65 years of age. Most gall stones, if impact in the bowel, are seen to lodge at the ileocecal valve as this is the most narrow part of the bowel. PRESENTATION OF CASE: We present a case of small intestinal obstruction because of a gallstone stuck in the distal jejunum. Patient was explored and one-stage surgery was done i...
October 4, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/30304966/choledocholithiasis-in-elderly-patients-with-gallbladder-in-situ-is-ercp-sufficient
#9
Mafalda Sousa, Rolando Pinho, Luísa Proença, Jaime Rodrigues, João Silva, Catarina Gomes, João Carvalho
INTRODUCTION: Along with increased life expectancy, the proportion of elderly patients with choledocholithiasis will increase and with this, the need for endoscopic cholangiopancreatography (ERCP). Current recommendations suggest laparoscopic cholecystectomy in all patients with choledocholithiasis to prevent biliary events. However, adherence to these recommendations is low, especially in older patients. METHODS: Retrospective study that included non-cholecystectomized patients aged > =75 years who underwent ERCP for choledocholithiasis from 2013-2016 (n = 131)...
October 10, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/30301711/incidence-and-epidemiological-features-of-acute-pancreatitis-among-adult-inhabitants-in-qatar
#10
Abdel-Naser Elzouki, Omar Alsaed, Abazar Saeed, Ahmed Ayash, Fahmi Yousef Khan
BACKGROUND/AIMS: Acute pancreatitis (AP) is one of the most common gastrointestinal causes of hospital admission in Qatar. The aim of the present study was to investigate the epidemiological features and demographic characteristics of patients with AP and to estimate the annual incidence rates of this disease among adult inhabitants in Qatar. MATERIALS AND METHODS: This retrospective study was conducted using the data collected by reviewing records of patients with AP admitted to the medical and surgical wards of Hamad GeneralHospital and Alkhor Hospital, Qatar from January 2007 to December 2012...
October 9, 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/30300790/a-rare-case-of-paraganglioma-of-the-cystic-duct
#11
Raha AlMarzooqi, Loay AlJaberi, Steven Rosenblatt, Thomas Plesec, Eren Berber
INTRODUCTION: Biliary system paragangliomas are rare neuroendocrine tumors of embryonic neural crest origin. The majority is asymptomatic and incidentally found due to gallbladder functional disorders. Herein, we present a non-functional, 2.25 mm focus in the cystic duct, which to our knowledge, is the first reported paraganglioma of the cystic duct. PRESENTATION OF CASE: The patient presented to the Emergency Department complaining of a sudden-onset, right upper abdominal and epigastric pain...
October 1, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/30298446/laparoscopic-transcystic-common-bile-duct-exploration-surgical-indications-and-procedure-strategies
#12
L Fang, J Wang, W C Dai, B Liang, H M Chen, X W Fu, B B Zheng, J Lei, C W Huang, S B Zou
BACKGROUND: LTCBDE combined with or without modified techniques is safe and efficacious for the management of gallstones and concomitant, even large, common bile duct (CBD) stones. METHODS: To describe the surgical indications and procedure strategies of laparoscopic transcystic common bile duct exploration (LTCBDE), a retrospective analysis of 205 patients with concomitant gallstones and CBD stones treated using LTCBDE between June 2008 and June 2015 was performed...
October 8, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30294430/a-new-clinical-ultrasound-score-to-predict-difficult-videolaparocholecystectomies-a-prospective-study
#13
Giuseppe Carbotta, Annunziata Panebianco, Rita Laforgia, Bianca Pascazio, Giovanni Balducci, Francesco Paolo Bianchi, Silvio Tafuri, Nicola Palasciano
Background: The gold standard treatment of symptomatic cholelithiasis is videolaparoscopic cholecystectomy (VLC). The aim of this study is to produce a predictive clinical ultrasound (US) score for difficult VLC to reduce the rate of conversion to open cholecystectomy surgery and intra and/or post-operative complications. Methods: In this prospective study carried out in 2017 we enrolled 135 patients (pts) who underwent VLC in our General Surgery Unit. A specific pre-operative abdominal ultrasound scan was performed to assess gallbladder characteristics for each patient...
November 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/30292986/-aged-autopsy-gallstones-simulating-dry-bone-context-a-morphological-histological-and-sem-eds-analysis
#14
Lucie Biehler-Gomez, Emanuela Maderna, Gloria Brescia, Annalisa Cappella, Agostino Rizzi, Cristina Cattaneo
OBJECTIVE: The aim of this paper is to provide information on the morphology and composition of gallstones based on clinical samples in order to assist paleopathologists and bioarchaeologists in recognizing their presence in archaeological contexts. MATERIALS AND METHODS: 270 gallstones were extracted and macerated from autopsies conducted at the Istituto di Medicina Legale in Milan (Italy) in order to simulate a dry bone recovered from archaeological contexts. Morphological, histological, and elemental variation was documented...
October 4, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/30292985/two-findings-of-gallstones-in-archaeological-mummies-from-colombia
#15
Felipe Cárdenas-Arroyo, Maria Cristina Martina
Results involving the analysis of gallstones found in two pre-Hispanic Colombian mummies are presented. By applying SEM, X-ray diffraction (XRD), sectioning, and CT-scan Hounsfield Units, we were able to identify these choleliths as mainly formed by cholesterol. The number of reports on gallstones in archaeological human remains from South America is very small, making these two cases an important addition to what little is known about ancient gallstone disease on the continent.
October 4, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/30288228/2-aminobenzimidazoles-as-antibiofilm-agents-against-salmonella-enterica-serovar-typhimurium
#16
William M Huggins, T Vu Nguyen, Nicholas A Hahn, James T Baker, Laura G Kuo, Darpan Kaur, Roberta J Melander, John S Gunn, Christian Melander
Serovars within the species Salmonella enterica are some of the most common food and water-borne pathogens worldwide. Some S. enterica serovars have shown a remarkable ability to persist both inside and outside the human body. Salmonella enterica serovar Typhi can cause chronic, asymptomatic infection of the human gallbladder. This organism's ability to survive inside the gallbladder centers around its ability to form biofilms on gallstone surfaces. Currently, chronic carriage of S. Typhi is treated by invasive methods, which are not well suited to areas where Salmonella carriage is prevalent...
September 1, 2018: MedChemComm
https://www.readbyqxmd.com/read/30286633/percutaneous-caecostomy-for-the-management-of-closed-loop-large-bowel-obstruction-a-delayed-complication-of-severe-gallstone-pancreatitis
#17
J Aldoori, J Cast, I A Hunter
Colonic complications following pancreatitis are unusual events ranging from 1% to 15%. In a patient with a hostile abdomen and multiple previous laparotomies, surgical management of a closed-loop large-bowel obstruction risks significant morbidity and mortality for the patient, necessitating other strategies for management. Caecostomy in the management of large bowel obstruction is an often forgotten weapon in the general surgeons' armoury.
October 5, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/30271604/distribution-of-the-atp-binding-cassette-transporter-abcg8-ivs1-2a-g-genotype-and-clinical-characteristics-of-gallbladder-patients-in-northeastern-mexico-a-pilot-study
#18
Pamela Frigerio, Ana Cecilia Cepeda-Nieto, Selim Marcos-Morales, Abel Peña-Velázquez, Sergio Dávila-Flores, Mauricio Salinas-Santander
Biliary lithiasis is a multifactorial pathology determined by the interaction of genes and the environment, characterized by alterations in cholesterol homeostasis and in the metabolism of bile salts. A number of gene polymorphisms and mutations have been identified in the ATP-dependent cholesterol transporter (ABCG8) associated with lithiasis disease. The aim of the present study was to evaluate the association of the ABCG8 gene mutation IVS1-2A>G with cholecystolithiasis in patients from Northeast Mexico...
September 2018: Biomedical Reports
https://www.readbyqxmd.com/read/30264011/splenic-abscess-following-laparoscopic-cholecystectomy-a-case-report-of-a-rare-disease-and-a-review-of-its-management
#19
Kevin Bain, Andrew Lelchuk, David Parizh, Vadim Meytes, Sampath Kumar
Splenic abscess is a rare disease that has several predisposing factors. Case reports have documented post-surgical development of splenic abscesses, most commonly after laparoscopic sleeve gastrectomy. We present the case of a 69-year-old female with gallstone pancreatitis who underwent an uncomplicated laparoscopic cholecystectomy. The hospital course was complicated by persistent postoperative leukocytosis with a CT scan demonstrating a moderate sized splenic abscess. Interventional radiology was consulted for percutaneous drainage, and the patient was subsequently discharged home in stable condition...
2018: AME case reports
https://www.readbyqxmd.com/read/30258310/gallbladder-agenesis-a-case-report
#20
Michelle C Salazar, Kirstyn E Brownson, Geoffrey S Nadzam, Andrew Duffy, Kurt E Roberts
Gallbladder agenesis (GA) is an extremely rare congenital entity. The incidence is around 1 per 6500 live births. The majority of patients, estimated between 50 to 70 percent, remain asymptomatic while those who are symptomatic report symptoms mimicking biliary colic. Initial workup for suspected gallbladder pathology such as right upper quadrant ultrasound (US) can be misleading or inconclusive. Furthermore, advanced diagnostic studies such as hepatobiliary iminodiacetic acid (HIDA) scan and endoscopic retrograde cholangio-pancreatography (ERCP) may report non-visualization of the gallbladder and erroneously lead providers to a diagnosis of cystic duct obstruction rather than GA...
September 2018: Yale Journal of Biology and Medicine
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