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https://www.readbyqxmd.com/read/30158671/correction-trim14-promotes-chemoresistance-in-gliomas-by-activating-wnt-%C3%AE-catenin-signaling-via-stabilizing-dvl2
#1
Zhanyao Tan, Libing Song, Wenjiao Wu, Yanqing Zhou, Jinrong Zhu, Geyan Wu, Lixue Cao, Junwei Song, Jun Li, Wei Zhang
Following the publication of this article the authors noted the affiliation details for corresponding author Dr. Wei Zhang was listed incorrectly. The correct affiliation is Neurosurgical Research Institute, The First Affiliated Hospital of Guangdong Pharmaceutics University, Guangzhou, China.
October 2018: Oncogene
https://www.readbyqxmd.com/read/30100655/pharmacokinetics-and-bioavailability-of-chromium-malate-and-its-influence-on-trace-metals-absorption-after-oral-or-intravenous-administration
#2
Weiwei Feng, Qian Li, Wei Wang, Ting Zhao, Yun Feng, Fang Li, Guanghua Mao, Yao Chen, Yangyang Ding, Liuqing Yang, Xiangyang Wu
OBJECTIVES: In our preliminary study, chromium malate could decrease the blood glucose level in mice with diabetes and exhibits good benefits in treating glycometabolism and adipose metabolization obstacle in rats with type 2 diabetes. This study was aimed at assessing the pharmacokinetics and bioavailability of chromium malate and influence on trace metals absorption in rats. METHODS: BAPP 2.3 pharmacokinetic calculating program (China Pharmaceutical University Medicine Center) was used to calculate the pharmacokinetic parameters...
March 2018: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/30050289/impact-of-multidisciplinary-collaborative-pharmaceutical-care-on-knowledge-adherence-and-efficacy-of-hormone-therapy-in-climacteric-women
#3
Min Lu, Ying Zhou, BaoJing Wang, ZheWen Hu, Ying Du, ShiFang Liu, XiuFeng Lin, YiMin Cui, HongYan Jin
Background: The objective of this study was to evaluate the impact of pharmaceutical care on the knowledge, adherence, and efficacy of hormone therapy in climacteric women participated in multidisciplinary collaborative clinic, launched by Peking University First Hospital (Beijing, People's Republic of China) in 2012. Methods: A total of 296 patients were recruited (intervention group n=150, control group n=146). The patients in the intervention group visited the multidisciplinary collaborative clinic for their initial hormone therapy, receiving individualized pharmaceutical care (PC), whereas the control group visited only the general clinic without PC...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29615066/a-qualitative-assessment-of-the-challenges-of-who-prequalification-for-anti-malarial-drugs-in-china
#4
Yangmu Huang, Ke Pan, Danlu Peng, Andy Stergachis
BACKGROUND: While China is a major manufacturer of artemisinin and its derivatives, it lags as a global leader in terms of the total export value of anti-malarial drugs as finished pharmaceutical products ready for marketing and use by patients. This may be due to the limited number of World Health Organization (WHO) prequalified anti-malarial drugs from China. Understanding the reasons for the slow progress of WHO prequalification (PQ) in China can help improve the current situation and may lead to greater efforts in malaria eradication by Chinese manufacturers...
April 3, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29546361/single-embryo-transfer-by-day-3-time-lapse-selection-versus-day-5-conventional-morphological-selection-a-randomized-open-label-non-inferiority-trial
#5
Lanlin Yang, Sufen Cai, Shuoping Zhang, Xiangyi Kong, Yifan Gu, Changfu Lu, Jing Dai, Fei Gong, Guangxiu Lu, Ge Lin
STUDY QUESTION: Does single cleavage-stage (Day 3) embryo transfer using a time-lapse (TL) hierarchical classification model achieve comparable ongoing pregnancy rates (OPR) to single blastocyst (Day 5) transfer by conventional morphological (CM) selection? SUMMARY ANSWER: Day 3 single embryo transfer (SET) with a hierarchical classification model had a significantly lower OPR compared with Day 5 SET with CM selection. WHAT IS KNOWN ALREADY: Cleavage-stage SET is an alternative to blastocyst SET...
May 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29535672/clinical-characteristics-of-juvenile-myasthenia-gravis-in-southern-china
#6
Xin Huang, Yingkai Li, Huiyu Feng, Pei Chen, Weibin Liu
Objectives: To describe the clinical profile, clinical outcomes and factors that may affect the outcome of juvenile myasthenia gravis (JMG) patients in southern China. Methods: We reviewed information relating to JMG patients treated and evaluated at the First Affiliated Hospital, Sun Yat-sen University, between 1998 and 2015. The study involved 327 JMG patients who had been followed up for ≥1 year. Results: Overall, 77.4% patients showed initial symptoms in the prepubertal period (<12 years)...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29458428/a-review-of-promoting-access-to-medicines-in-china-problems-and-recommendations
#7
REVIEW
Jing Sun, Cecile Jia Hu, Mark Stuntz, Hans Hogerzeil, Yuanli Liu
BACKGROUND: Despite recent reforms, distorting funding mechanisms and over-prescribing still maintain severe financial barriers to medicines access in China. Complicated and interrelated problems in the pharmaceutical sector require a common framework to be resolved as fragmented solutions do not work. We present a preliminary assessment of the impact of the national healthcare reforms on access to medicines, and propose policy recommendations for promoting universal access to medicines in China...
February 20, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/28966164/first-person-jinhang-hu
#8
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Jinhang Hu is the first author on 'CCR2 3'UTR functions as a competing endogenous RNA to inhibit breast cancer metastasis', published in Journal of Cell Science. Jinhang conducted the work in this article in Tao Xi's lab at China Pharmaceutical University, Nanjing, China. She is now a research associate with Zhishu Tang at the Shaanxi University of Chinese Medicine in Xian Yang, China, investigating the bioactive constituents and anti-tumour mechanisms of the active ingredients in traditional Chinese medicine...
October 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28910938/-comparison-of-commercial-hiv-1-viral-load-tests-by-using-proficiency-test-results-in-china-2013-2015
#9
L Zhang, C Jin, Z Jiang, T Tang, Y Jiang, P L Pan
Objective: To compare the bio-equivalence among commercial HIV-1 viral load tests, including EasyQ HIV-1 v2.0 (EasyQ) from bioMerieux NucliSens of France; VERSANT HIV-1 RNA 3.0 assay (bDNA) from Siemens Healthcare Diagnostics of USA; COBAS AmpliPrep/COBAS TaqMan HIV-1 test (Taqman) from Roche Molecular Diagnosis of USA; Abbott Real Time HIV-1 Kit (M2000) from Abbott Molecular of USA and two domestic HIV-1 viral load test kits (domestic kit) from DaAn Gene Company of Sun Yat-Sen University and Liaoning Bio-Pharmaceutical company of Northeast pharmaceutical group, by using proficiency test results in China from 2013 to 2015...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28507433/effect-of-pharmaceutical-care-on-clinical-outcomes-of-outpatients-with-type-2-diabetes-mellitus
#10
Hua Shao, Guoming Chen, Chao Zhu, Yongfei Chen, Yamin Liu, Yuxing He, Hui Jin
BACKGROUND: In the People's Republic of China, outpatients have limited time with their physicians. Thus, compared to inpatients, outpatients have lower medication adherence and are less knowledgeable about their disease. OBJECTIVE: The objective of this study was to evaluate the effect of pharmaceutical care on clinical outcomes of outpatients with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS: A randomized, controlled, prospective clinical trial was conducted recruiting a total of 240 T2DM outpatients from Zhongda Hospital, Southeast University...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28343208/legal-features-of-the-drug-advertising
#11
REVIEW
Vitalii M Pashkov, Andrii A Olefir, Oleksiy Y Bytyak
INTRODUCTION: In the article discribed current trends of advertising in the pharmaceutical market and foreign experience of legal regulation of these relations. As for the advertising of medicines identified it's symptoms, types, basic rules and prohibitions. Modern pharmaceutical companies can not successfully carry out economic activities without advertising. Besides we can mention some fundamental changes in society (information overload, universal access to internet, social media, freedom of movement of goods, labor and finance), also self-medication becomes more popular...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27828672/healthcare-systems-the-state-and-innovation-in-the-pharmaceutical-industry
#12
REVIEW
Ignacio José Godinho Delgado
This article discusses the relations between healthcare systems and the pharmaceutical industry, focusing on state support for pharmaceutical innovation. The study highlights the experiences of the United States, United Kingdom, and Germany, developed countries and paradigms of modern health systems (liberal, universal, and corporatist), in addition to Japan, a case of successful catching up. The study also emphasizes the experiences of China, India, and Brazil, large developing countries that have tried different catching up strategies, with diverse histories and profiles in their healthcare systems and pharmaceutical industries...
November 3, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27686945/induction-chemotherapy-plus-concurrent-chemoradiotherapy-versus-concurrent-chemoradiotherapy-alone-in-locoregionally-advanced-nasopharyngeal-carcinoma-a-phase-3-multicentre-randomised-controlled-trial
#13
RANDOMIZED CONTROLLED TRIAL
Ying Sun, Wen-Fei Li, Nian-Yong Chen, Ning Zhang, Guo-Qing Hu, Fang-Yun Xie, Yan Sun, Xiao-Zhong Chen, Jin-Gao Li, Xiao-Dong Zhu, Chao-Su Hu, Xiang-Ying Xu, Yuan-Yuan Chen, Wei-Han Hu, Ling Guo, Hao-Yuan Mo, Lei Chen, Yan-Ping Mao, Rui Sun, Ping Ai, Shao-Bo Liang, Guo-Xian Long, Bao-Min Zheng, Xing-Lai Feng, Xiao-Chang Gong, Ling Li, Chun-Ying Shen, Jian-Yu Xu, Ying Guo, Yu-Ming Chen, Fan Zhang, Li Lin, Ling-Long Tang, Meng-Zhong Liu, Jun Ma
BACKGROUND: The value of adding cisplatin, fluorouracil, and docetaxel (TPF) induction chemotherapy to concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma is unclear. We aimed to compare TPF induction chemotherapy plus concurrent chemoradiotherapy with concurrent chemoradiotherapy alone in a suitably powered trial. METHODS: We did an open-label, phase 3, multicentre, randomised controlled trial at ten institutions in China. Patients with previously untreated, stage III-IVB (except T3-4N0) nasopharyngeal carcinoma, aged 18-59 years without severe comorbidities were enrolled...
November 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27570834/advancing-cancer-survivorship-in-a-country-with-1-35-billion-people-the-china-lymphoma-project
#14
Steven Coughlin, Jamie Reno
Rates of lymphoma are rising rapidly and lymphoma is now the ninth most common cancer among Chinese males. The China Lymphoma Project was founded to increase awareness of lymphoma in China, including the survivability of the disease and the availability of potentially life-saving treatments, and to provide social support for men, women, and children in China who are living with the disease. The project is working with China government officials, several of the top cancer hospitals in China and the U.S., internationally known oncologists and cancer researchers, pharmaceutical and biotech companies in China and the U...
2016: Journal of Environment and Health Sciences
https://www.readbyqxmd.com/read/27525917/molecular-identification-and-phylogenetic-analysis-of-important-medicinal-plant-species-in-genus-paeonia-based-on-rdna-its-matk-and-rbcl-dna-barcode-sequences
#15
W J Kim, Y Ji, G Choi, Y M Kang, S Yang, B C Moon
This study was performed to identify and analyze the phylogenetic relationship among four herbaceous species of the genus Paeonia, P. lactiflora, P. japonica, P. veitchii, and P. suffruticosa, using DNA barcodes. These four species, which are commonly used in traditional medicine as Paeoniae Radix and Moutan Radicis Cortex, are pharmaceutically defined in different ways in the national pharmacopoeias in Korea, Japan, and China. To authenticate the different species used in these medicines, we evaluated rDNA-internal transcribed spacers (ITS), matK and rbcL regions, which provide information capable of effectively distinguishing each species from one another...
August 5, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27436298/the-effect-of-herd-formation-among-healthcare-investors-on-health-sector-growth-in-china
#16
Zhou Lulin, Henry Asante Antwi, Wenxin Wang, Ethel Yiranbon, Emmanuel Opoku Marfo, Patrick Acheampong
BACKGROUND: China has become the world's second largest healthcare market based on a recent report by the World Health Organization. Eventhough China achieved universal health insurance coverage in 2011, representing the largest expansion of insurance coverage in human history achieved; health inequality remains endemic in China. Lessons from the effect of market crisis on health equity in Europe and other places has reignited interest in exploring the potential healthcare market aberrations that can trigger distributive injustice in healthcare resource allocation among China's provinces...
July 19, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27297624/news-from-tartary-an-ethnopharmacological-approach-to-drug-and-therapeutic-discovery
#17
REVIEW
Nicholas Moore, Nawel Hamza, Benedicte Berke, Anwar Umar
Ethnopharmacology aims to identify new therapeutic agents based on their traditional use. It begins by the identification of disease states, and of the traditional therapies for these, most commonly herbals. Herbals of interest are selected from ethnopharmacological surveys, and tested on experimental models of the diseases of interest. Once the activity of the traditional remedy is demonstrated, including dose-dependence, if possible comparatively to reference medications, the active ingredients can be explored, if possible using bioguided extraction...
January 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27123180/a-review-of-accessibility-of-administrative-healthcare-databases-in-the-asia-pacific-region
#18
Dominique Milea, Soraya Azmi, Praveen Reginald, Patrice Verpillat, Clement Francois
OBJECTIVE: We describe and compare the availability and accessibility of administrative healthcare databases (AHDB) in several Asia-Pacific countries: Australia, Japan, South Korea, Taiwan, Singapore, China, Thailand, and Malaysia. METHODS: The study included hospital records, reimbursement databases, prescription databases, and data linkages. Databases were first identified through PubMed, Google Scholar, and the ISPOR database register. Database custodians were contacted...
2015: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/27030797/analyzing-the-chinese-landscape-in-anti-diabetic-drug-research-leading-knowledge-production-institutions-and-thematic-communities
#19
Junling Deng, Kaweng Sitou, Yongping Zhang, Ru Yan, Yuanjia Hu
BACKGROUND: The discovery of anti-diabetic drugs is an active Chinese medicine research area. This study aims to map out anti-diabetic drug research in China using a network-based systemic approach based on co-authorship of academic publications. We focused on identifying leading knowledge production institutions, analyzing interactions among them, detecting communities with high internal associations, and exploring future research directions. METHODS: Target articles published in 2009-2013 under the topic "diabetes" and subject category "pharmacology & pharmacy," with "China," "Taiwan," "Hong Kong," or "Macao" (or "Macau") in the authors' address field were retrieved from the science citation index expanded database and their bibliographic information (e...
2016: Chinese Medicine
https://www.readbyqxmd.com/read/26787019/effectiveness-of-problem-based-learning-in-chinese-pharmacy-education-a-meta-analysis
#20
REVIEW
Jiyin Zhou, Shiwen Zhou, Chunji Huang, Rufu Xu, Zuo Zhang, Shengya Zeng, Guisheng Qian
BACKGROUND: This review provides a critical overview of problem-based learning (PBL) practices in Chinese pharmacy education. PBL has yet to be widely applied in pharmaceutical education in China. The results of those studies that have been conducted are published in Chinese and thus may not be easily accessible to international researchers. Therefore, this meta-analysis was carried out to review the effectiveness of PBL. METHODS: Databases were searched for studies in accordance with the inclusion criteria...
January 19, 2016: BMC Medical Education
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