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Generalized anxiety disorder

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https://www.readbyqxmd.com/read/29038094/transdiagnostic-psychodynamic-web-based-self-help-intervention-following-inpatient-psychotherapy-results-of-a-feasibility-study-and-randomized-controlled-trial
#1
Rüdiger Zwerenz, Jan Becker, Robert Johansson, Ronald J Frederick, Gerhard Andersson, Manfred E Beutel
BACKGROUND: Mental disorders have become a major health issue, and a substantial number of afflicted individuals do not get appropriate treatment. Web-based interventions are promising supplementary tools for improving health care for patients with mental disorders, as they can be delivered at low costs and used independently of time and location. Although psychodynamic treatments are used frequently in the face-to-face setting, there has been a paucity of studies on psychodynamic Web-based self-help interventions...
October 16, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29037266/is-cognitive-behavioural-therapy-more-effective-than-relaxation-therapy-in-the-treatment-of-anxiety-disorders-a-meta-analysis
#2
Jesus Montero-Marin, Javier Garcia-Campayo, Alba López-Montoyo, Edurne Zabaleta-Del-Olmo, Pim Cuijpers
BACKGROUND: It is not clear whether relaxation therapies are more or less effective than cognitive and behavioural therapies in the treatment of anxiety. The aims of the present study were to examine the effects of relaxation techniques compared to cognitive and behavioural therapies in reducing anxiety symptoms, and whether they have comparable efficacy across disorders. METHOD: We conducted a meta-analysis of 50 studies (2801 patients) comparing relaxation training with cognitive and behavioural treatments of anxiety...
October 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29036532/behavioral-pattern-separation-and-its-link-to-the-neural-mechanisms-of-fear-generalization
#3
Iris Lange, Liesbet Goossens, Stijn Michielse, Jindra Bakker, Shmuel Lissek, Silvia Papalini, Simone Verhagen, Nicole Leibold, Machteld Marcelis, Marieke Wichers, Ritsaert Lieverse, Jim van Os, Therese van Amelsvoort, Koen Schruers
Fear generalization is a prominent feature of anxiety disorders and post-traumatic stress disorder. It is defined as enhanced fear responding to a stimulus that bears similarities, but is not identical to a threatening stimulus. Pattern separation, a hippocampal-dependent process, is critical for stimulus discrimination; it transforms similar experiences or events into non-overlapping representations. The current study is the first in humans to investigate the extent to which fear generalization relies on behavioral pattern separation abilities...
September 26, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29036201/impact-of-social-separation-during-pregnancy-on-the-manifestation-of-defensive-behaviors-related-to-generalized-anxiety-and-panic-throughout-offspring-development
#4
Flaviane Cristina de Brito Guzzo Soliani, Rafael Cabbia, Matheus Fitipaldi Batistela, Amarylis Garcia Almeida, Vinícius Dias Kümpel, Luiz Yamauchi Junior, Telma Gonçalves Carneiro Spera de Andrade
The multiple insecurities, anatomical, physiological and psychological changes arising from the gestational period can generate an overload of stress in the mother and cause disturbances in the offspring, affecting it throughout its development. The existing analysis linking prenatal stress and offspring's anxiety have divergent results, being limited as to gestational week, type of stressor and age of progeny's assessment. Social separation has been described as a stressor that causes increase in anxiety. Thus, the present study evaluated the effects of social separation applied in one of the three gestational weeks of rat dams on the manifestation of the defensive behaviors related to generalized anxiety disorder and panic in the Elevated T Maze of the male progeny in three stages of development (1, 3 or 6 months of life)...
2017: PloS One
https://www.readbyqxmd.com/read/29034525/reliability-and-validity-of-severity-dimensions-of-psychopathology-assessed-using-the-structured-clinical-interview-for-dsm-5-scid
#5
Stewart A Shankman, Carter J Funkhouser, Daniel N Klein, Joanne Davila, Debra Lerner, Danelle Hee
This study examined whether the Structured Clinical Interview for DSM (SCID), a widely used semistructured interview designed to assess psychopathology categorically, can be adapted to identify reliable and valid severity dimensions of psychopathology. The present study also examined whether these severity dimensions have better psychometric properties (internal consistency, test-retest reliability, and concurrent and predictive validity) than categorical diagnoses. Participants (N = 234) were recruited from the community and clinics...
October 16, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/29034083/the-effect-of-cognitive-behavioral-counseling-on-anxiety-in-the-mothers-of-infants-in-the-nicu-%C3%A2-a-randomized-controlled-trial
#6
Massumeh Koochaki, Zohreh Mahmoodi, Sara Esmaelzadeh-Saeieh, Kourosh Kabir, Maryam Tehranizadeh, Mahrokh Dolatian
Background: Pressures and tensions in everyone's life can cause a wide range of mental disorders such as anxiety. One of these tensions is the birth of a baby who requires special care, which can cause personal and social problems for the mother if no appropriate measures are taken to help them. The present study was conducted to determine the effect of cognitive-behavioral counseling on anxiety in the mothers of infants in the Neonatal Intensive Care Unit. Methods: This randomized controlled trial recruited 90 women presenting to Kowsar Hospital in Qazvin in 2016...
2017: F1000Research
https://www.readbyqxmd.com/read/29033027/anhedonia-following-early-life-adversity-involves-aberrant-interaction-of-reward-and-anxiety-circuits-and-is-reversed-by-partial-silencing-of-amygdala-corticotropin-releasing-hormone-gene
#7
Jessica L Bolton, Jenny Molet, Limor Regev, Yuncai Chen, Neggy Rismanchi, Elizabeth Haddad, Derek Z Yang, Andre Obenaus, Tallie Z Baram
BACKGROUND: Anhedonia, the diminished ability to experience pleasure, is an important dimensional entity linked to depression, schizophrenia, and other emotional disorders, but its origins and mechanisms are poorly understood. We have previously identified anhedonia, manifest as decreased sucrose preference and social play, in adolescent male rats that experienced chronic early-life adversity/stress (CES). Here we probed the molecular, cellular, and circuit processes underlying CES-induced anhedonia and tested them mechanistically...
September 7, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29033017/neurocognitive-and-psychological-outcomes-in-adults-with-dextro-transposition-of-the-great-arteries-corrected-by-the-arterial-switch-operation
#8
Leïla Kasmi, Johanna Calderon, Michèle Montreuil, Nikoletta Geronikola, Virginie Lambert, Emrè Belli, Damien Bonnet, David Kalfa
BACKGROUND: Neurodevelopmental impairments have frequently been described in children and adolescents with dextro-transposition of the great arteries (d-TGA). The arterial switch operation (ASO) to correct d-TGA has been used for more than 30 years, and more than 90% of these patients now reach adulthood. However, very little is known about their long-term functional outcomes. The present study investigated neurocognitive outcomes and the prevalence of psychiatric disorders in adults with d-TGA corrected by ASO...
October 12, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29031568/anxiety-disorders-in-old-age-psychiatric-comorbidities-quality-of-life-and-prevalence-according-to-age-gender-and-country
#9
Alessandra Canuto, Kerstin Weber, Marc Baertschi, Sylke Andreas, Jana Volkert, Maria Christina Dehoust, Susanne Sehner, Anna Suling, Karl Wegscheider, Berta Ausín, Mike J Crawford, Chiara Da Ronch, Luigi Grassi, Yael Hershkovitz, Manuel Muñoz, Alan Quirk, Ora Rotenstein, Ana Belén Santos-Olmo, Arieh Shalev, Jens Strehle, Hans-Ulrich Wittchen, Holger Schulz, Martin Härter
OBJECTIVES: Previous estimates of the prevalence of anxiety disorders in late life vary greatly due to the lack of reliable diagnostic tools. This MentDis_ICF65+ study assessed 12-month prevalence rates of anxiety disorders and age- and gender-related differences in comorbidities, as well as impact on quality of life. DESIGN: The study used a cross-sectional multicenter survey. PARTICIPANTS: The study sample comprised 3,142 men and women aged 65 to 84 years, living in five European countries and Israel...
September 5, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29031217/quality-of-life-and-burden-in-caregivers-of-youth-with-obsessive-compulsive-disorder-presenting-for-intensive-treatment
#10
Monica S Wu, Rebecca Hamblin, Joshua Nadeau, Jessica Simmons, Ashley Smith, Meredith Wilson, Stephanie Eken, Brent Small, Vicky Phares, Eric A Storch
BACKGROUND: Pediatric obsessive-compulsive disorder (OCD) is associated with deleterious familial effects; caregivers are often enmeshed in the disorder and can experience considerable burden and decreased quality of life (QoL). Consequently, this study examined burden and QoL in caregivers of youth with OCD enrolled in an intensive outpatient or partial hospitalization program. METHOD: The relationships between caregiver QoL and burden and the following variables were investigated: OCD symptom severity, functioning (youth functional impairment, general family functioning), family (family accommodation, parental relationship satisfaction, positive aspects of caregiving), and comorbid psychopathology (caregiver anxiety and depressive symptoms, youth internalizing and externalizing behaviors)...
August 30, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29028610/systematic-review-and-meta-analysis-of-dropout-rates-in-individual-psychotherapy-for-generalized-anxiety-disorder
#11
REVIEW
Elon Gersh, David J Hallford, Simon M Rice, Nikolaos Kazantzis, Hannah Gersh, Benji Gersh, Carolyn A McCarty
BACKGROUND: Despite being a relatively prevalent and debilitating disorder, Generalized Anxiety Disorder (GAD) is the second least studied anxiety disorder and among the most difficult to treat. Dropout from psychotherapy is concerning as it is associated with poorer outcomes, leads to service inefficiencies and can disproportionately affect disadvantaged populations. No study to date has calculated a weighted mean dropout rate for GAD and explored associated correlates. METHODS: A systematic review was conducted using PsycINFO, Medline and Embase databases, identifying studies investigating individual psychotherapies for adults with GAD...
October 6, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29026765/screening-antenatal-anxiety-predicting-its-effect-on-fetal-growth
#12
Kaushik Sarkar, Goutam Das, Ranadip Chowdhury, Bhaskar Shahbabu, Ishita Sarkar, Santu Maiti, Aparajita Dasgupta
CONTEXT: Maternal anxiety has an association with low birth weight. However, studies are scarce to determine any association between maternal anxiety and fetal growth. AIMS: This study aims to determine the effect of maternal anxiety on fetal growth, measured by gestational age-dependent increase in fetal abdominal circumference (AC). The secondary objective is to determine the effect of maternal anxiety on other fetal parameters (biparietal diameter [BPD], head circumference [HC], femur length [FL])...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29026329/pharmacogenomic-testing-aiding-in-the-management-of-psychotropic-therapy-for-adolescents-with-autism-spectrum-disorders
#13
Seuli Bose-Brill, Jinming Xing, Debra J Barnette, Christopher Hanks
Adolescents with autism have higher rates of anxiety than the general adolescent population. They often struggle to express psychological symptoms verbally where their symptoms may manifest as withdrawal and agitation. Adolescent patients with autism have higher rates of polypharmacy and high-risk psychiatric medication use (eg, atypical antipsychotics) than other patients with psychiatric illness. Primary care pediatricians are at the front lines of psychiatric management for patients with autism. Yet, they have inadequate access to pediatric psychiatry for complex medication management...
2017: Pharmacogenomics and Personalized Medicine
https://www.readbyqxmd.com/read/29025788/brief-mindfulness-meditation-for-depression-and-anxiety-symptoms-in-patients-undergoing-hemodialysis-a-pilot-feasibility-study
#14
Zoë Thomas, Marta Novak, Susanna Gabriela Torres Platas, Maryse Gautier, Angela Potes Holgin, Rebecca Fox, Marilyn Segal, Karl J Looper, Mark Lipman, Steven Selchen, Istvan Mucsi, Nathan Herrmann, Soham Rej
BACKGROUND AND OBJECTIVES: Up to 50% of patients undergoing hemodialysis suffer from symptoms of depression and/or anxiety. Access to traditional pharmacotherapies and psychotherapies for depression or anxiety in this patient population has been inadequate. The objective of this study was to investigate the feasibility and effectiveness of brief mindfulness meditation intervention for patients on hemodialysis with depression and anxiety symptoms. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This study was a randomized, controlled, assessor-blinded trial conducted in an urban hemodialysis unit...
October 12, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29023466/training-discrimination-diminishes-maladaptive-avoidance-of-innocuous-stimuli-in-a-fear-conditioning-paradigm
#15
Miriam J J Lommen, Mihaela Duta, Koen Vanbrabant, Rachel de Jong, Keno Juechems, Anke Ehlers
Anxiety disorders are the most common mental disorder worldwide. Although anxiety disorders differ in the nature of feared objects or situations, they share a common mechanism by which fear generalizes to related but innocuous objects, eliciting avoidance of objects and situations that pose no objective risk. This overgeneralization appears to be a crucial mechanism in the persistence of anxiety psychopathology. In this study we test whether an intervention that promotes discrimination learning reduces generalization of fear, in particular, harm expectancy and avoidance compared to an irrelevant (control) training...
2017: PloS One
https://www.readbyqxmd.com/read/29023223/point-prevalence-and-patterns-of-mental-health-co-morbidity-among-people-accessing-australia-s-first-older-adult-specific-alcohol-and-other-drug-treatment-service
#16
Stephen Bright, Katherine Walsh, Cylie Williams
OBJECTIVE: There is good data regarding the prevalence and patterns of dual diagnosis among the general population; however, data regarding the older adult cohort is limited. We aimed to extend the knowledge of the point prevalence and patterns of dual diagnosis among older adults, and the impact of dual diagnosis on the utilization of Alcohol and Other Drug (AOD) treatment services. METHOD: A 12 month medical chart audit of clients discharged from an Australian older adult-specific AOD treatment service...
October 12, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29022840/irritable-temperament-and-lifetime-psychotic-symptoms-as-predictors-of-anxiety-symptoms-in-bipolar-disorder
#17
Gianluca Serafini, Pierre A Geoffroy, Andrea Aguglia, Giulia Adavastro, Giovanna Canepa, Maurizio Pompili, Mario Amore
PURPOSE: Affective temperaments, hopelessness, alexithymia, and anxiety/agitation symptoms may play a significant role in the psychopathological characteristics of bipolar disorder (BD). Here, we aimed to investigate the eventual association between the mentioned explanatory variables and anxiety/agitation symptoms in BD. MATERIALS AND METHODS: We recruited at the Section of Psychiatry, Department of Neuroscience, University of Genoa (Italy), 92 BD inpatients having a mean age of 52 (±13...
October 12, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29020064/canine-companionship-is-associated-with-modification-of-attentional-bias-in-posttraumatic-stress-disorder
#18
Steven H Woodward, Andrea L Jamison, Sasha Gala, Tyson H Holmes
Attentional bias towards aversive stimuli has been demonstrated in the anxiety disorders and in posttraumatic stress disorder, and attentional bias modification has been proposed as a candidate treatment. This study rigorously assessed attentional bias towards aversive and pleasant visual imagery associated with the presence or absence of a familiar service canine in 23 veterans with chronic military-related posttraumatic stress disorder. Participants were repeatedly tested with and without their service canines present on two tasks designed to elicit spontaneous visual attention to facial and scenic image pairs, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/29018562/local-availability-of-green-and-blue-space-and-prevalence-of-common-mental-disorders-in-the-netherlands
#19
Sjerp de Vries, Margreet Ten Have, Saskia van Dorsselaer, Manja van Wezep, Tia Hermans, Ron de Graaf
BACKGROUND: Previous studies revealed a relationship between residential green space availability and health, especially mental health. Studies on blue space are scarcer and results less conclusive. AIMS: To investigate the hypotheses that green and blue space availability are negatively associated with anxiety and mood disorders, and positively associated with self-reported mental and general health. METHOD: Health data were derived from a nationally representative survey (NEMESIS-2, n=6621), using a diagnostic interview to assess disorders...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/29018394/distress-levels-among-parents-of-active-duty-soldiers-during-wartime
#20
Shahar Bitton, Rivka Tuval-Mashiach, Sara Freedman
Objective: Military service is a highly stressful period both for the soldiers serving and for their parents. Surprisingly, parents' experience has been mostly ignored in the research. This study's goal is to shed light on the experience and distress levels of parents of active duty combat soldiers during Operation Protective Edge, a military operation carried out by the Israel Defense Forces during July and August of 2014. Methods: During the advanced stages of the operation, 69 parents of Israeli male combat soldiers (55 mothers and 14 fathers) completed an online survey measuring symptoms of Posttraumatic Stress Disorder (PTSD-Checklist-5) and distress (Brief Symptom Inventory-18)...
2017: Frontiers in Psychology
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