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Generalized anxiety disorder

David M Lyons, Christine L Buckmaster, Alan F Schatzberg
Repeated exposure to a same-sex resident stranger enhances subsequent indications of active coping that generalize across multiple contexts in intruder male mice. Here we investigate female mice for comparable learning to cope training effects. Stress coping research focused on females is important because stress related mood and anxiety disorders are more prevalent in women than men. Female mice were monitored for coping behavior in open-field, object-exploration, and tail-suspension tests conducted after repeated exposure to a same-sex resident stranger...
June 9, 2018: Psychoneuroendocrinology
Benjamin Hon Kei Yip, Xue Li, Christine Hiu Yan Leung, Ting Gao, Vincent Chi Ho Chung, Fiona Wai Ping Yu, Tsz Ping Lam, Jack Chun Yiu Cheng, Samuel Yeung Shan Wong
INTRODUCTION: Adolescent idiopathic scoliosis (AIS) is the most prevalent deforming orthopaedic condition; it causes significant disability when spinal curves progress beyond 45deg. Bracing is the primary treatment prescribed for adolescents with an immature skeleton who have spinal curves between 25 and 45deg. New evidence suggests that compliance with bracing significantly decreases the progression of high-risk curves to the threshold for surgery. Nonetheless, bracing is a stressful experience...
June 12, 2018: Journal of Physiotherapy
Fernanda Pedrotti Moreira, Carolina David Wiener, Karen Jansen, Luis Valmor Portela, Diogo R Lara, Luciano Dias de Mattos Souza, Ricardo Azevedo da Silva, Jean Pierre Oses
OBJECTIVE: The aim of this study was to verify the serum GDNF levels in individuals with anxiety disorder (AD) in a population-based study. METHODS: This was a cross-sectional study population-based, with people aged 18 to 35. AD's assessment was performed using the Mini International Neuropsychiatric Interview (M.I.N.I). Serum GDNF was measured by ELISA using a commercial kit. RESULTS: The prevalence was 3.3% for post-traumatic stress disorder, 6...
June 12, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
Jonathan H Hsu, Zafiris J Daskalakis, Daniel M Blumberger
PURPOSE: Review recent meta-analyses and clinical trials investigating the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) for concurrent pain and depressive symptoms. RECENT FINDINGS: Recent meta-analyses have included both pain and depression outcomes in fibromyalgia and chronic pain. Randomized controlled trials have also been conducted in post-herpetic neuralgia, trauma-related headache, and neuropathic pain with attention to both pain and depressive symptoms...
June 14, 2018: Current Pain and Headache Reports
Amneh Al-Husseini, Mayyada Wazaify, Marie Claire Van Hout
Pregabalin is currently approved for the treatment of epilepsy, generalized anxiety disorder, neuropathic pain, and fibromyalgia. A qualitative study was undertaken in Jordan, where concerns have been raised about its unprescribed availability in community pharmacies and thereby its abuse. Semi-structured interviews were conducted with all patients with a history of pregabalin use in two Jordanian addiction treatment centers. All were male patients aged 21-30 years ( n  = 11). The majority was poly-drug abusers and had a previous history of substance abuse (tramadol, Captagon, synthetic cannabinoids, and marijuana) ...
2018: International Journal of Mental Health and Addiction
Michael N Mongelli, Benjamin J Peipert, Sneha Goswami, Irene Helenowski, Susan E Yount, Cord Sturgeon
BACKGROUND: Patient-reported outcomes are measured in chronic disease states to inform intervention and management decisions while minimizing negative outcomes. We hypothesized that health-related quality of life in patients with multiple endocrine neoplasia type 2A would be worse than the general US population but similar to other chronic diseases. METHODS: Adults ≥18 years with multiple endocrine neoplasia type 2A were recruited to complete the Patient-Reported Outcomes Measurement Information System 29-item questionnaire (n = 45)...
June 11, 2018: Surgery
Linbo Wei, Juan Li, Yanpei Cao, Jianming Xu, Wei Qin, Huijuan Lu
So far, liver transplantation (LT) has become the most effective way to treat end-stage liver-related diseases. As we all know, a stable caregiver is crucial to LT recovery. However, compared with LT patients, few studies were focused on LT caregivers.This study aimed to describe the quality of life (QoL), care burden, and their related factors in caregivers of LT patients in Shanghai, China.We collected 225 liver transplanted patients and their corresponding caregivers' social demographic and medical information; meanwhile, we assessed 225 LT recipients' caregivers' life quality; by using Caregiver Quality of Life Index-Liver Transplantation in Chinese version (CQOLC-LT), Zarit caregiver burden inventory in Chinese version (ZBI) was used to access the care burden...
June 2018: Medicine (Baltimore)
Ravi Kumar Thetakala, B R Chandrashekar, S Sunitha, M Maurya, Priyanka Sharma, G Shubhi
Background: One of the widespread problems of oral health is bruxism and is defined as a parafunctional habit with involuntary grinding and gnashing of the teeth occurring during sleep. However, bruxism is connected to anxiety and stress, but the published literature on bruxism among prison inmates is scanty. Objective: The objective of the study was to determine the prevalence of active sleep bruxism and its impact on oral health-related quality of life (OHRQoL) among inmates in Central Penal Institution, Mysore...
May 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
Erika A Crawford, Taylor A Burke, David Siegel, Shari Jager-Hyman, Lauren B Alloy, Philip C Kendall
OBJECTIVE: The severity of anxiety, in general, has been associated with suicide ideation (SI) among youth, but research has yet to examine the specific anxiety symptoms that may contribute to SI among youth. This study examined the severity of specific anxiety symptom clusters (i.e., tense/restless, somatic/autonomic symptoms, humiliation/rejection, performing in public, separation anxiety, perfectionism, and anxious coping) and SI in youth who met diagnostic criteria for an anxiety disorder...
June 14, 2018: Suicide & Life-threatening Behavior
Béré Mahoney
Fear and anxiety about aging have increased amongst female university students and these personal aging concerns are associated with disturbed eating, also prevalent in this group. Evidence suggests concern about aging appearance could account for the link between aging anxiety and problem eating in young women due to their belief in the thin - youth ideal. However, whether appearance concern is the strongest aging anxiety predictor of global and specific disturbed eating behaviors is unclear. The study examines this in a sample of female students at a Midlands university in the United Kingdom (N = 200, 18 - 39 years) who completed the Anxiety about Aging Scale and the Eating Disorders Inventory-3...
March 2018: Europe's Journal of Psychology
Carlos Bernardo Tauil, Talyta Cortez Grippe, Ronaldo Maciel Dias, Rafael Paternò Castello Dias-Carneiro, Narel Moita Carneiro, Ana Carolina Rodrigues Aguilar, Flávia Martins da Silva, Felipe Bezerra, Leonardo Kenzo de Almeida, Vitoria Lana Massarente, Elaine de Carvalho Giovannelli, Charles Peter Tilbery, Carlos Otávio Brandão, Leonilda Maria B Santos, Leopoldo Dos Santos-Neto
INTRODUCTION: Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation. METHODS: One hundred and thirty two patients with relapsing-remitting MS were evaluated using the Expanded Disability Status Scale, Beck Depression Inventory-II (BDI-II), Beck Scale for Suicide Ideation (BSI), and Hospital Anxiety and Depression Scale...
May 2018: Arquivos de Neuro-psiquiatria
Erika J Wolf, Mark W Logue, Filomene G Morrison, Elizabeth S Wilcox, Annjanette Stone, Steven A Schichman, Regina E McGlinchey, William P Milberg, Mark W Miller
BACKGROUND: Posttraumatic stress disorder (PTSD) and stress/trauma exposure are cross-sectionally associated with advanced DNA methylation age relative to chronological age. However, longitudinal inquiry and examination of associations between advanced DNA methylation age and a broader range of psychiatric disorders is lacking. The aim of this study was to examine if PTSD, depression, generalized anxiety, and alcohol-use disorders predicted acceleration of DNA methylation age over time (i...
June 13, 2018: Psychological Medicine
Adam Simning, Meghan L Fox, Steven L Barnett, Silvia Sorensen, Yeates Conwell
OBJECTIVE: The objective of the study is to examine the association of auditory, vision, and dual sensory impairment with late-life depressive and anxiety symptoms. METHOD: Our study included 7,507 older adults from the National Health & Aging Trends Study, a nationally representative sample of U.S. Medicare beneficiaries. Auditory and vision impairment were determined by self-report, and depressive and anxiety symptoms were evaluated by the two-item Patient Health Questionnaire (PHQ-2) and two-item Generalized Anxiety Disorder Scale (GAD-2), respectively...
June 1, 2018: Journal of Aging and Health
Khalid Al Risi, Mandhar Al Maqbali, Waddah Alalmaei Asiri, Hamed Al Sinawi
Objectives: Tobacco smoking is the single most avoidable cause of morbidity and mortality around the world. Patients with psychiatric disorders tend to smoke tobacco at a higher rate than the general population, with significant adverse health consequences. This study aimed to determine the rate of tobacco smoking among psychiatric outpatients attending Sultan Qaboos University Hospital, a tertiary care hospital in Muscat, Oman. Methods: We conducted a cross-sectional study among psychiatric outpatients attending a psychiatric clinic from 1 January to 1 August 2017...
May 2018: Oman Medical Journal
Heide Klumpp, Bobak Hosseini, K Luan Phan
Sufficient sleep plays an important role in neurocognitive function, yet, problematic sleep is ubiquitous in the general population. It is also frequently predictive of, and concurrent with, internalizing psychopathologies (IPs) such as anxiety and depression suggesting sleep quality is dimensional and transdiagnostic. Along with problematic sleep, IPs are characterized by negative affectivity, therefore, prominent neurobiological models of internalizing conditions involve the amygdala, a region central to emotion...
2018: Frontiers in Psychiatry
Girija Kaimal, Melissa S Walker, Joanna Herres, Louis M French, Thomas J DeGraba
OBJECTIVES: The study aimed tocompare recurring themes in the artistic expression of military service members (SMs) with post-traumatic stress disorder (PTSD), traumatic brain injury and psychological health (PH) conditions with measurable psychiatric diagnoses. Affective symptoms and struggles related to verbally expressing information can limit communication in individuals with symptoms of PTSD and deployment-related health conditions. Visual self-expression through art therapy is an alternative way for SMs with PTSD and other PH conditions to communicate their lived experiences...
June 11, 2018: BMJ Open
Anke Köbach, Martina Ruf-Leuschner, Thomas Elbert
BACKGROUND: Anecdotal evidence suggests the frequently traumatic nature of female genital mutilation (FGM). At present, systematic research on the psychological sequelae of this tradition has remained limited. The study provides preliminary, high-quality psychodiagnostic data on potential psychopathological consequences of FGM, with a focus on posttraumatic stress disorder (PTSD), shutdown dissociation and other stress-related variables. METHODS: We investigated a convenience sample of N = 167 women, supported by the women's affairs headquarters in Jijiga (capital of the Ethiopian Somali Region) and a local Ethiopian non-governmental organization...
June 13, 2018: BMC Psychiatry
Silvia Cerea, Gioia Bottesi, Quirico F Pacelli, Antonio Paoli, Marta Ghisi
Muscle Dysmorphia (MD) is a psychological disorder characterized by the preoccupation with the idea that one's body is not lean and muscular. The current study aimed to explore MD behaviours and symptoms in three groups of recreational athletes: bodybuilders (BB; n = 42), strength athletes (SA; n = 61), and fitness practitioners (FP; n = 22). Furthermore, we assessed MD-related psychological features as well as possible psychological predictors of MD among groups. Results highlighted that the BB group reported more beliefs about being smaller and weaker than desired compared to the other groups, whereas individuals in the SA group reported setting higher standards for themselves than the FP group...
June 11, 2018: Scientific Reports
Gehan Botrus, Omar Baker, Erica Borrego, Kyari Sumayin Ngamdu, Mohamed Teleb, Jose L Gonzales Martinez, Gerardo Maldonado, Ahmed M Hussein, Richard McCallum
Joint hypermobility is a common, primarily benign finding in the general population. However, in a subset of individuals joint hypermobility causes a range of clinical problems mainly affecting the musculoskeletal system and, to a lesser extent, extra-articular disorders. Joint hypermobility often appears as a familial trait and is shared by several inherited connective tissue disorders, including the hypermobility subtype of Ehlers-Danlos syndrome (hEDS) and benign joint hypermobility syndrome (BJHS/JHS). Although joint hypermobility has primarily been thought of as a rheumatological disorder, increasing evidence shows significant associations between both hEDS and BJHS with specific extra-articular disorders...
June 2018: American Journal of the Medical Sciences
Kenta Ishikawa, Hikaru Suzuki, Matia Okubo
BACKGROUND AND OBJECTIVES: Individuals with social anxiety have various types of deficiencies in emotional processing. Diversity of deficiencies may imply that socially anxious individuals have malfunctions in fundamental parts of emotional processing. Therefore, we hypothesized that social anxiety contributes to deficiencies in building on the metaphorical relationship between emotional experience and brightness. METHODS: We conducted a judgment task of valences of faces with manipulated clothing brightness (bright or dark)...
June 5, 2018: Journal of Behavior Therapy and Experimental Psychiatry
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