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Gabriela Lacet Silva Ferreira, Pedro Luiz Rosalen, Larissa Rangel Peixoto, Ana Luiza Alves de Lima Pérez, Fabíola Galbiatti de Carvalho Carlo, Lúcio Roberto Cançado Castellano, Jefferson Muniz de Lima, Irlan Almeida Freires, Edeltrudes de Oliveira Lima, Ricardo Dias de Castro
We evaluated the antifungal and anti-biofilm activity, mechanism of action and cytotoxicity of chloramine T trihydrate (CAT) against Candida spp. The Minimum Inhibitory and Fungicidal Concentrations (MIC/MFC) of CAT were determined. Changes in CAT-treated C. albicans growth kinetics and micromorphology were evaluated, as well as the mechanism of action, and its effects on biofilm. Cytotoxicity was assessed by the hemolysis method. The data were analyzed by inferential statistics (p ≤ 0.05). CAT showed antifungal activity against all strains, with MIC values ranging between 1...
September 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Anna Beatriz Temoteo Delgado, Caio Cesar Vaz Lacet Gondim, Lucas Pereira Reichert, Pedro Hugo Vieira da Silva, Rodrigo Marmo da Costa E Souza, Thiago Monteiro de Paiva Fernandes, Bernardino Fernandez Calvo
The Bothrops spp. venom contain metalloproteinases that contributes to vascular and hemorrhagic effects. This case report describes a 58 years-old patient from the city of Dona Inês, Paraiba, Brazil victim of an ophidian accident by Bothrops spp. The vascular and hemorrhagic effects of venom components have triggered a hemorrhagic stroke. Brazil has about 600 deaths annually due to ophidian accidents. However, as reports have been precarious, the obtaining of epidemiological-clinical data has been affected...
June 15, 2017: Toxicon: Official Journal of the International Society on Toxinology
Larissa Rangel Peixoto, Pedro Luiz Rosalen, Gabriela Lacet Silva Ferreira, Irlan Almeida Freires, Fabíola Galbiatti de Carvalho, Lúcio Roberto Castellano, Ricardo Dias de Castro
OBJECTIVE: The present study demonstrated the antifungal potential of the chemically characterized essential oil (EO) of Laurus nobilis L. (bay laurel) against Candida spp. biofilm adhesion and formation, and further established its mode of action on C. albicans. METHODS: L. nobilis EO was obtained and tested for its minimum inhibitory and fungicidal concentrations (MIC/MFC) against Candida spp., as well as for interaction with cell wall biosynthesis and membrane ionic permeability...
January 2017: Archives of Oral Biology
Celina Maria Costa Lacet, João Batista Neto, Laercio Tenório Ribeiro, Francisco Silva Oliveira, Rozangela Fernandes Wyszomirska, Edna Strauss
UNLABELLED:  Background. Upper gastrointestinal bleeding is a major cause of morbidity and mortality in patients with portal hypertension secondary to schistosomiasis mansoni. AIM: To evaluate the efficacy of combined surgery and sclerotherapy versus endoscopic treatment alone in the prophylaxis of esophageal variceal rebleeding due to portal hypertension in schistosomiasis. MATERIAL AND METHODS: During a two-years period consecutive patients with schistosomiasis and a recent bleeding history were evaluated for prospective randomization...
September 2016: Annals of Hepatology
Ricardo Dias de Castro, Trícia Murielly Pereira Andrade de Souza, Louise Morais Dornelas Bezerra, Gabriela Lacet Silva Ferreira, Edja Maria Melo de Brito Costa, Alessandro Leite Cavalcanti
BACKGROUND: Limitations of antifungal agents used in the treatment of oral candidiasis, as the development of resistant strains, are known by the scientific community. In this context, the aim of this study was to evaluate the antifungal activity of thymol against Candida albicans, Candida tropicalis and Candida krusei strains and to determine its mode of action and synergistic effect when combined with the synthetic antifungal nystatin. METHODS: The minimum inhibitory concentration (MIC) was determined using a microdilution technique, and the minimum fungicidal concentration (MFC) was determined via subculture sowing...
2015: BMC Complementary and Alternative Medicine
Dimitrios Sfoungaris, Vassilios Mouravas
INTRODUCTION: Redo orchiopexy involves a hazardous dissection inside the inguinal canal (IC) where scar tissue encircles the testicular vessels (TesV), vas deferens (VD), and the testis. OBJECTIVE: The aim was to describe and evaluate a combined preperitoneal and inguinal approach (CPI) through a single cutaneous incision and accomplish this task as safely as possible, at the same time permitting additional maneuvers for cord lengthening. MATERIAL AND METHODS: We prospectively studied eight patients aged from 2...
February 2016: Journal of Pediatric Urology
Smalyanna Sgren da Costa Andrade, Ana Aline Lacet Zaccara, Kamila Nethielly Souza Leite, Karen Krystine Gonçalves de Brito, Maria Júlia Guimarães Oliveira Soares, Marta Miriam Lopes Costa, Ana Karina Bezerra Pinheiro, Simone Helena Dos Santos Oliveira
OBJECTIVE: Assessing the adequacy of knowledge, attitude and practice of women regarding male and female condoms as STI/HIV preventive measures. METHOD: An evaluative Knowledge, Attitude and Practice (KAP) household survey with a quantitative approach, involving 300 women. Data collection took place between June and August 2013, in an informal urban settlement within the municipality of João Pessoa, Paraiba, Northeast Brazil. RESULTS: Regarding the male condom, most women showed inadequate knowledge and practice, and an adequate attitude...
June 2015: Revista da Escola de Enfermagem da U S P
Gabriela Lacet Silva Ferreira, Ana Luíza Alves de Lima Pérez, Ítalo Martins Rocha, Mayara Abreu Pinheiro, Ricardo Dias de Castro, Hugo Lemes Carlo, Edeltrudes de Oliveira Lima, Lúcio Roberto Castellano
In view of the limitations of antifungal agents used in the treatment of oral candidiasis and the wide variety of natural products that have been studied as treatment of this disease, this systematic literature review proposed to evaluate whether scientific evidence attesting to the efficacy of natural products in the treatment of this disease exists. A systematic search in PubMed, MEDLINE, SciELO, Lilacs, and Cochrane Library databases was accomplished using the associations among the keywords Candida albicans, phytotherapy, biological products, denture stomatitis, and oral candidiasis in both English and Portuguese...
2015: Evidence-based Complementary and Alternative Medicine: ECAM
José Resende de Castro Júnior, Natália Fernandes, Thiago Bento de Paiva Lacet, Fábio Simplício Maia, Glauco Resende Bonato, Cristianne Nogueira, Sílvio Henrique Barberato, Rogério Baumgratz de Paula
INTRODUCTION: Hypertension is highly prevalent in patients with chronic kidney disease and hypervolemia is one of the principal causes. OBJECTIVE: To evaluate the influence of the reduction of volemia on blood pressure as well as on echocardiographic parameters in patients on continuous ambulatory peritoneal dialysis. METHODS: Twelve patients with no clinical evidence of hypervolemia were submitted to an increase in the rate of the dialysis with the purpose of reducing body weight by 5%...
October 2014: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
Irlan de Almeida Freires, Livia Araújo Alves, Gabriela Lacet Silva Ferreira, Vanessa de Carvalho Jovito, Ricardo Dias de Castro, Alessandro Leite Cavalcanti
Objectives. This study aimed to investigate the efficacy of a Schinus terebinthifolius (ST) mouthwash in reducing gingival inflammation levels (GI) and biofilm accumulation (BA) in children with gingivitis. Methods. This was a randomized, controlled, triple blind, and phase II clinical trial, with children aged 9-13 years (n = 27) presenting with biofilm-induced gingivitis. The sample was randomized into experimental (0.3125% ST, n = 14) and control (0.12% chlorhexidine/CHX, n = 13) groups. Products were masked as regards color, flavor and aroma...
2013: Evidence-based Complementary and Alternative Medicine: ECAM
José Lacet Lima, Eduardo Dias-Ribeiro, Julierme Ferreira-Rocha, Ramon Soares, Fábio Wildson Gurgel Costa, Song Fan, Eduardo Sant'ana
We compared the buccal infiltration of 4% articaine with 1 : 100,000 or 1 : 200,000 epinephrine without a palatal injection for the extraction of impacted maxillary third molars with chronic pericoronitis. This prospective, double-blind, controlled clinical trial involved 30 patients between the ages of 15 and 46 years who desired extraction of a partially impacted upper third molar with pericoronitis. Group 1 (15 patients) received 4% articaine with 1 : 100,000 epinephrine and group 2 (15 patients) received 4% articaine with 1 : 200,000 epinephrine by buccal infiltration...
2013: Anesthesia Progress
Yu Chen, Cuiping Liu, Liping Cui
UNLABELLED: Patient male, 27 year old. Left facial and head trauma for 6 hours, due to motor vehicle accident. Patient state of mind was clear at arrival to hospital. Body temperature: 36C; Pulse: 80 Time/Minute; Breath: 20 Time/Minute; Blood pressure: 120/80 mm Hg. An irregular, horizontal laceration at arch of left eyebrow, approximately 8-10 cm. A laceration on left wing of nose skin, approximately 1 cm. A laceration also under lower eyelid skin of right eye, approximately 2 cm. Left blepharedema and enophthalmos...
January 2013: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
José Lacet de Lima, Eduardo Dias-Ribeiro, Evaldo Sales Honfi, Túlio Neves de Araújo, Kilma Keilla Honório de Góes, Maria do Socorro Aragão
The Odontogenic Keratocyst is a developmental odontogenic cyst and deserves special attention because of its peculiar histopathologic features and biologic behavior. It is believed that the Odontogenic Keratocyst arises from the proliferation of remnants of dental lamina. It is usually asymptomatic, and solitary lesion, however, it may be associated with Nevoid Basal Cell Carcinoma Syndrome. This work aimed to present a case of a very extensive Odontogenic Keratocyst in a 28-year-old woman.
October 2006: Indian Journal of Otolaryngology and Head and Neck Surgery
Moisés Carminatti, Thiago Lacet, Dominique Fonseca Rodrigues, Maria de Lourdes Junqueira, Fernando César Rodrigues, Marcus Gomes Bastos, Natália Maria da Silva Fernandes
We describe the clinical course of a case of peritonitis caused by Salmonella sp. after an episode of intestinal salmonellosis, and a brief review of the literature is also done.
March 2012: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
Marize Raquel Diniz da Rosa, James Maxwell Souza de Oliveira, Eduardo Dias-Ribeiro, Julierme Ferreira-Rocha, Iolanda Maria Cariry Carvalho Lacet de Barros, Patricia de Medeiros Loureiro Lopes
Calcifying epithelial odontogenic tumor (CEOT) is a rare, locally invasive neoplasm characterized by the presence of amyloid material that can become calcified. It often is found in the posterior region of the mandible. Such tumors in the maxilla and those that invade the maxillary sinus are extremely rare. This article presents the sixth reported clinical case of a CEOT that invaded the maxillary sinus and extended to the interior of the nasal cavity. The tumor had grown toward the sinus roof, but there was no association with an impacted tooth...
January 2011: General Dentistry
Darlene Gabeau-Lacet, David Engler, Sumeet Gupta, George A Scangas, Rebecca A Betensky, Fred G Barker, Jay S Loeffler, David N Louis, Gayatry Mohapatra
Atypical meningiomas exhibit heterogeneous clinical outcomes. It is unclear which atypical meningiomas require aggressive multimodality treatment with surgery and radiation therapy versus surgery alone to prevent recurrence. Detailed molecular-genetic characterization of these neoplasms is necessary to understand their pathogenesis and identify clinically relevant genetic markers. Oligonucleotide array comparative genomic hybridization was used to identify frequent genetic alterations in 47 primary atypical meningiomas resected at Massachusetts General Hospital between August 1987 and September 2006...
October 2009: Journal of Neuropathology and Experimental Neurology
Natáia Maria da Silva Fernandes, Patrícia dos Santos Pinto, Thiago Bento de Paiva Lacet, Dominique Fonseca Rodrigues, Marcus Gomes Bastos, Sérgio Reinaldo Stella, Miguel Cendoroglo Neto
INTRODUCTION: Acute renal failure (ARF) remains highly prevalent with a high rate of morbidity and mortality. OBJECTIVE: of this study was to compare use of the APACHE II scoring prognosis with that of the ATN-ISS to determine whether the APACHE II could be used for patients with ARF outside the ICU. METHODS: For this purpose, 205 patients with ARF were accompanied in a prospective cohort. Demographic data, preexisting conditions, organ failure and characteristics of ARF were analyzed...
July 2009: Revista da Associação Médica Brasileira
Darlene Gabeau-Lacet, Manish Aghi, Rebecca A Betensky, Fred G Barker, Jay S Loeffler, David N Louis
OBJECT: The authors identified clinical features associated with progression and death in atypical meningioma (AM). METHODS: Forty-seven cases of primary AM treated at Massachusetts General Hospital were retrospectively evaluated for clinical features. Associations with progression-free survival (PFS) and overall survival were assessed. RESULTS: The estimated median PFS was 56 months (95% CI 35 months-not estimable). The overall 3- and 5-year PFS rates were 65% (95% CI 44-80%) and 48% (95% CI 26-67%), respectively...
September 2009: Journal of Neurosurgery
José-Lacet Lima-Júnior, Eduardo Dias-Ribeiro, Túlio-Neves de Araújo, Julierme Ferreira-Rocha, Evaldo-Sales Honfi-Júnior, Carlos-Frederico de Moraes Sarmento, Flávio-Roberto-Guerra Seabra, Maria do Socorro-Cirilo de Sousa
AIMS: The aim of this study was to evaluate the vestibular-palatal diffusion of 4% Articaine with epinephrine 1:100,000 and 1:200,000, in impacted maxillary third molar extractions, without palatal injection. MATERIALS AND METHOD: Two hundred teeth were selected from patients age 15 to 46. Patients were divided into 4 groups: 1A, were anesthetized with 4% articaine 1:100,000 and the surgery was initiated 5 minutes following anesthesia. 1B, used 4% articaine 1:100,000 but the surgery was started 10 minutes after anesthesia...
March 2009: Medicina Oral, Patología Oral y Cirugía Bucal
Gilles Chironi, Damian Craiem, Janiffer Miranda-Lacet, Jaime Levenson, Alain Simon
OBJECTIVES: Our aim was to analyze flow-mediated dilation (FMD) time-course in response to forearm occlusion in the clinical setting. METHODS AND RESULTS: In 50 asymptomatic subjects, monitoring software measuring continuous beat-to-beat change in brachial artery diameter was used to determine FMD magnitude in percentage change in peak diameter from baseline (FMD-DeltaD), time to peak diameter after occlusion release (FMD-t(peak)), integrated FMD response calculated as area under dilation curve (FMD-AUC), maximum FMD rate calculated as maximal slope of dilation (FMD-MDR)...
March 2008: Journal of Hypertension
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