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https://www.readbyqxmd.com/read/28358324/anti-inflammatory-effect-of-titrated-extract-of-centella-asiatica-in-phthalic-anhydride-induced-allergic-dermatitis-animal-model
#1
Ju Ho Park, Ji Yeon Choi, Dong Ju Son, Eun Kyung Park, Min Jong Song, Mats Hellström, Jin Tae Hong
Centella asiatica has potent antioxidant and anti-inflammatory properties. However, its anti-dermatitic effect has not yet been reported. In this study, we investigated the anti-dermatitic effects of titrated extract of Centella asiatica (TECA) in a phthalic anhydride (PA)-induced atopic dermatitis (AD) animal model as well as in vitro model. An AD-like lesion was induced by the topical application of five percent PA to the dorsal skin or ear of Hos:HR-1 mouse. After AD induction, 100 μL of 0.2% and 0.4% of TECA (40 μg or 80 μg/cm²) was spread on the dorsum of the ear or back skin three times a week for four weeks...
March 30, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28134155/flare-up-of-nickel-contact-dermatits-following-oral-challenge
#2
C R Srinivas, C Balachandran, K K Singh, S D Shenoy, D S Krupashankar
A patient having contact dermatitis due to nickel on the wrist, sides of neck, thighs and legs, confirmed by patch tests with nickel sulphate, showed aggravation of the dermatitis following oral provocation with 25 mg nickel sulphate.
March 1988: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/19134436/sorbitan-sesquioleate-a-common-emulsifier-in-topical-corticosteroids-is-an-important-contact-allergen
#3
Adam Asarch, Pamela L Scheinman
BACKGROUND: In the past, sorbitan sesquioleate (SSO) was reported as an uncommon allergen, but recent data suggest SSO may be an important sensitizer. OBJECTIVE: To present data on 13 of 112 dermatitis patients who reacted to SSO and/or sorbitan monooleate (SMO) on patch testing. METHODS: A retrospective data analysis was conducted on data from 112 dermatitis patients patch-tested from December 2006 to May 2007. All patients were tested with a modified North American Contact Dermatitis Group standard series, a cosmetic series, and a fragrance series...
November 2008: Dermatitis
https://www.readbyqxmd.com/read/19016307/contact-dermatitis-caused-by-sunless-tanning-treatment-with-dihydroxyacetone-in-hairless-descendants-of-mexican-hairless-dogs
#4
Tohru Kimura
Dihydroxyacetone (DHAT) is a color additive that is added to sunless tanning products to produce an artificial tan. Although this agent has been used extensively as safe sunless tanning, no published data are available to judge whether the abuse of DHAT causes a potential hazard to the human skin. The purpose of this study was to clarify whether frequent treatment with DHAT solutions had a deleterious effect on the wide skin surface of hairless descendants of Mexican hairless dogs. The skin reactions to the DHAT-treatment were investigated by daily clinical observations and histopathological examinations (21 and 42 days after the beginning of the DHAT-treatment)...
October 2009: Environmental Toxicology
https://www.readbyqxmd.com/read/18173194/-contact-sensitization-to-antioxidants-in-rubber-industry-workers
#5
M Paravina, G Ristić, J Todorović, M Petrović
The most frequent contact allergens in rubber industry are antioxidants, substances against again of rubber. The aim of the work is determining their role in generating of allergic contact dermatitis (ACD) in rubber industry workers depending on the kind of antioxidants, sex of workerw, lenght of working, pace of work. 68 workers (first group) with contact dermatitic and 40 of healthy workerw (second group) in rubber industry were examined. Patch tests and LIF on 5 antioxidants were done. Positive patch tests had 54,41% workers from first group and 17,50% of workers from second group...
1994: Srpski Arhiv za Celokupno Lekarstvo
https://www.readbyqxmd.com/read/17301385/dermal-wound-fibroblasts-and-matrix-metaloproteinases-mmps-their-possible-role-in-allergic-contact-dermatitis
#6
Mohammad Reza Khorramizadeh, Reza Falak, Mohammad Pezeshki, Farnaz Safavifar, Parvin Mansouri, Aziz Ghahary, Farshid Saadat, Kamran Varshokar
This study was conducted to examine if allergic contact dermatitis (ACD) alters the expression of MMPs in human dermal fibroblasts. Fibroblasts are the primary source for MMP and matrix production in skin. MMPs are known to involve in a number of physiological and pathological processes. Some published data indicated a gelatinase-like activity in acute and chronic phases of allergic contact dermatitis. However, no exact source of gelatinase activity was demonstrated. Moreover, little is known about the role of MMPs in immune responses...
March 2004: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/16956467/cutaneous-reactions-to-injectable-corticosteroids
#7
Nilam Amin, Ronald Brancaccio, David Cohen
Corticosteroids are used to treat a variety of medical conditions. While topical preparations are known to commonly cause allergic contact dermatits, systemic use of these drugs rarely causes cutaneous reactions. (This paper presents) Two cases of (systemic) injectable corticosteroid use resulting in delayed hypersensitivity reactions are presented.
September 2006: Dermatitis
https://www.readbyqxmd.com/read/15274740/occupational-allergic-contact-dermatits-caused-by-padauk-wood-pterocarpus-soyauxii-taub
#8
Marta Kiec-Swierczynska, Beata Krecisz, Dominika Swierczynska-Machura, Cezary Palczynski
No abstract text is available yet for this article.
June 2004: Contact Dermatitis
https://www.readbyqxmd.com/read/15029432/-perianal-dermatitis-and-its-benign-simulants
#9
S Proske, B H Lenhard, W Hartschuh
Perianal dermatitis is one of the most common proctological disorders. Concerning the etiology, three different types of dermatitis must be distinguished-the most common irritative contact dermatitis, atopic dermatitis and allergic contact dermatitis. The correct diagnosis is essential for adequate and successful treatment. A variety of benign and malignant disorders must be considered in the differential diagnosis of anal dermatitis. Dermatitic clinical disorders which do not respond to therapy should always be biopsied...
March 2004: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/12145450/prevalence-of-fragrance-allergy
#10
Pamela L Scheinman
With the exception of the UK, where fragrance allergy remained fairly constant from the early 1980s until the mid-late 1990s, other centers worldwide (Denmark, Singapore, Slovenia and the USA) reported an increase in fragrance allergy during this period. The ubiquitous nature of fragrance in modern society, coupled with new and growing markets of fragrance products for children and men, likely contribute to this increase. Strict adherence to voluntary guidelines on concentration limits of known fragrance sensitizers in consumer products is necessary...
2002: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/11924808/latex-sensitivity-in-a-macaque-macaca-mulatta
#11
J D Macy, M J Huether, T A Beattie, H A Findlay, C Zeiss
UNLABELLED: BACKGROUND AND HISTORY: An adult Macaca mulatta was examined because of a history of multiple episodes of conjunctivitis and an acute, pruritic, dermatitic eruption that affected the axillary and inguinal regions, forearms, thorax, and neck. METHODS AND RESULTS: Results of corneal staining, examination of skin scrapings and feces, fungal culture, CBC, and a thyroid profile (thyroxine/triiodothyronine concentrations) were negative or normal, with the exception of eosinophilia (1,040/mm3)...
October 2001: Comparative Medicine
https://www.readbyqxmd.com/read/11873257/-epidemic-dermatits-by-paederus-irritans-in-piura-per%C3%A3%C2%BA-at-1999-related-to-el-ni%C3%A3-o-phenomenon
#12
Victor Alva-Davalos, Victor Alberto Laguna-Torres, A Huaman, R Olivos, M Chavez, C Garcia, N Mendoza
The phenomen El Niño that affected Peru at 1998, made possible the growth of copious vegetation in traditionally dry places. On this way, Paederus irritans, dipterous of the order Coleoptera that produces dermatitis when croushed on the skin, found substract that allowed the natural growth of its population. The coming of occasional rains on the months of February to April 1999, attacked the habitat of this insect, that looked for urban areas, exposing seriously the general population of Piura on north Perú to the contact...
January 2002: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/11807430/allergic-contact-dermatitis-to-detergents-a-multicenter-study-to-assess-prevalence
#13
MULTICENTER STUDY
Donald V Belsito, Anthony F Fransway, Joseph F Fowler, Elizabeth F Sherertz, Howard I Maibach, James G Mark, C G Toby Mathias, Robert L Rietschel, Frances J Storrs, James R Nethercott
BACKGROUND: Allergic contact dermatitis (ACD) to optical brighteners and enzymes in laundry detergents was the focus of numerous reports in the early 1970s. Subsequently, there has been little published on the incidence of allergic reactions to chemicals in laundry detergents. Nonetheless, consumers and physicians continue to ascribe allergic contact reactions to laundry detergents. OBJECTIVE: This article reports the findings of a multicenter study on the prevalence of patch test reactions to a liquid and a granular laundry detergent provided by Procter & Gamble Company (Cincinnati, Ohio)...
February 2002: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/10321941/comparative-study-of-staphylococci-from-the-skin-of-atopic-dermatitis-patients-and-from-healthy-subjects
#14
COMPARATIVE STUDY
S Higaki, M Morohashi, T Yamagishi, Y Hasegawa
BACKGROUND: Bacterial infections occur frequently on the skin of atopic dermatitis (AD) patients. The objectives of this study were to evaluate the microbiology of the skin of AD patients for staphylococci, the frequency and density of each species, and their susceptibility to antimicrobial drugs. METHODS: To study the staphylococci present on the skin of 21 AD outpatients and of 12 healthy subjects (HS), cutaneous organisms were obtained using the contact-plate method...
April 1999: International Journal of Dermatology
https://www.readbyqxmd.com/read/9523978/contact-allergens-from-surfactants-atmospheric-oxidation-of-polyoxyethylene-alcohols-formation-of-ethoxylated-aldehydes-and-their-allergenic-activity
#15
M Bergh, L P Shao, G Hagelthorn, E Gäfvert, J L Nilsson, A T Karlberg
Ethoxylated surfactants are susceptible to oxidation upon air exposure. We have previously studied the rate of peroxidation and formaldehyde formation in the chemically well-defined ethoxylated alcohol C12H25(OCH2CH2)5OH. Formaldehyde is a common cause of contact allergy. The aim of the present study was to identify other oxidation products that could be formed upon air exposure of the ethoxylated alcohol and to determine their allergenic activity. It was shown that air oxidation of C12H25(OCH2CH2)5OH gave all the theoretically possible aldehydes of the general formula C12H25(OCH2CH2)nOCH2CHO (n = 0-4) and that the major oxidation product was C12H25(OCH2CH2)4OCH2CHO, dodecyltetraoxyethyleneoxyacetaldehyde...
March 1998: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/9158415/loss-of-cutaneous-delayed-hypersensitivity-reactions-in-nevus-anemicus-evidence-for-close-concordance-of-cutaneous-delayed-hypersensitivity-and-endothelial-e-selectin-expression
#16
H Mizutani, S Ohyanagi, Y Umeda, M Shimizu, T S Kupper
BACKGROUND: The relationship of adhesion molecules in the dermis to immunologically mediated cutaneous inflammation can be understood by focusing on a serendipitous phenomenon: a lack of dermatitis within the margins of a nevus anemicus (NA) in generalized contact dermatitis. The expression and induction of endothelial and epithelial adhesion molecules with intradermally injected cytokines were investigated. OBSERVATIONS: Nevus anemicus without dermatitis lacked histopathological changes consistent with inflammatory cellular infiltration...
May 1997: Archives of Dermatology
https://www.readbyqxmd.com/read/8957638/isolated-colophony-allergens-as-screening-substances-for-contact-allergy
#17
A T Karlberg, E Gäfvert
Rosin has a complex chemical composition. The aim of this study was to investigate if it is possible to define 1 or 2 compounds as the rosin allergens. 2 compounds, 13, 14(beta)-epoxyabietic acid and 7-oxodehydroabietic acid, identified in gum rosin and tall oil rosin, were used as screening substances for patch testing in addition to the standard series. The rosin patch detected more cases of contact allergy than the isolated allergens did. Our suggestion is to patch test with a preparation of gum rosin, as well-defined as possible, for screening...
October 1996: Contact Dermatitis
https://www.readbyqxmd.com/read/8884147/tachyphylaxis-to-histamine-induced-wheal-suppression-by-topical-0-05-clobetasol-propionate-in-normal-versus-croton-oil-induced-dermatitic-skin
#18
COMPARATIVE STUDY
S Singh, A Gupta, S S Pandey, G Singh
BACKGROUND: Patients often tell about reduced effectiveness of topical steroids on repeated use. Tachyphylaxis to these agents has been demonstrated in humans for vasoconstriction and histamine-induced wheal suppression in normal skin, but not in diseased skin. Relevance of these data to diseased skin is not clear. Further, the clinical impression does not appear to match tachyphylaxis shown in normal skin with regard to the time course. OBJECTIVES: To examine whether tachyphylaxis to histamine-induced wheal suppression by a topical steroid occurs in dermatitic skin and to determine its time course vis-à-vis normal skin...
1996: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/6686577/isoeugenol-a-survey-of-consumer-patch-test-sensitization
#19
G R Thompson, K A Booman, J Dorsky, K A Kohrman, A S Rothenstein, E A Schwoeppe, R I Sedlak, R J Steltenkamp
The potential of isoeugenol, an important fragrance and flavour ingredient, to induce delayed contact hypersensitivity or to elicit pre-existing sensitization reactions in man was evaluated by analysing patch-test data from dermatitic and non-dermatitic subjects. Results from a total of 6512 patch tests (involving approximately 5850 subjects) on isoeugenol alone and on various consumer products and fragrance blends containing isoeugenol, were collected from fragrance and formulator companies. Hypersensitivity induced by isoeugenol was concentration dependent...
December 1983: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/6686575/cinnamic-aldehyde-a-survey-of-consumer-patch-test-sensitization
#20
P J Danneman, K A Booman, J Dorsky, K A Kohrman, A S Rothenstein, R I Sedlak, R J Steltenkamp, G R Thompson
The potential for cinnamic aldehyde, an important fragrance and flavour ingredient, to induce or to elicit delayed contact hypersensitivity reactions in man was evaluated by analysing patch-test data. Results of studies involving a total of 4117 patch tests on various consumer products and fragrance blends containing cinnamic aldehyde and on the material itself were collected from fragrance and formulator companies. The data indicate that cinnamic aldehyde contained in consumer products and fragrance blends at concentrations up to 6 X 10(-1)%, and patch-tested at concentrations up to 8 X 10(-3)%, has no detectable potential to induce hypersensitivity...
December 1983: Food and Chemical Toxicology
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