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Coronary imaging

Qin Li, Benjamin P Berman, Tomoe Hagio, Marios A Gavrielides, Rongping Zeng, Berkman Sahiner, Qi Gong, Yuan Fang, Songtao Liu, Nicholas P Petrick
Extracting coronary artery calcium (CAC) scores from contrast-enhanced computed tomography (CT) images using dual-energy (DE) based material decomposition has been shown feasible, mainly through patient studies. However, the quantitative performance of such DE-based CAC scores, particularly per-stenosis, is underexamined due to lack of reference standard and repeated scans. In this work we conducted a comprehensive quantitative comparative analysis of CAC scores obtained with DE and compare to conventional unenhanced single-energy (SE) CT scans through phantom studies...
August 13, 2018: Physics in Medicine and Biology
Carina T Domingues, Milan Milojevic, Daniel J F M Thuijs, Nicolas M van Mieghem, Joost Daemen, Ron T van Domburg, A Pieter Kappetein, Stuart J Head
OBJECTIVES: The Heart Team has been recommended as standard care for patients with coronary artery disease (CAD). However, little is known about the real benefits, potential treatment delays and late outcomes of this approach. Our goal was to determine the safety and feasibility of multidisciplinary Heart Team decision making for patients with CAD. METHODS: We retrospectively assessed 1000 consecutive cases discussed by the Heart Team between November 2010 and January 2012...
August 7, 2018: Interactive Cardiovascular and Thoracic Surgery
Dong-Yeon Kim, Sang-Geon Cho, Hee-Seung Bom
Myocardial perfusion imaging using positron emission tomography (PET) has several advantages over single photon emission computed tomography (SPECT). The recent advances in SPECT technology have shown promise, but there is still a large need for PET in the clinical management of coronary artery disease (CAD). Especially, absolute quantification of myocardial blood flow (MBF) using PET is extremely important. In spite of considerable advances in the diagnosis of CAD, novel PET radiopharmaceuticals remain necessary for the diagnosis of CAD because clinical use of current cardiac radiotracers is limited by their physical characteristics, such as decay mode, emission energy, and half-life...
August 2018: Nuclear Medicine and Molecular Imaging
Ahmed Abuosa, Jamilah AlRahimi, Nasir Mansour, Ashar Bilal, Atif AlQabbani, Akram Neyaz
A case of a young Saudi patient with a previous diagnosis of bronchial asthma, nasal polyps, and chronic smoker, presented with atypical chest pain, elevated serum troponin and borderline ischemic electrocardiogram (ECG) changes, with no significant regional wall motion abnormalities at bedside echocardiography is reported. The patient was admitted to the coronary care unit for continuous monitoring as possible acute coronary syndrome, non-ST elevation myocardial infarction (STEMI). One hour after admission, the patient had ventricular fibrillation (VF) cardiac arrest that required three DC shocks and amiodarone bolus before returning of spontaneous circulation, which followed the fourth shock...
October 2018: Journal of the Saudi Heart Association
Hiroya Asou, Naoyuki Imada, Yuichi Nishiyama, Tomoyasu Sato, Katsuhiro Ichikawa
PURPOSE: The aim of the present study was to develop an automated system for determining the cardiac rest period during whole-heart coronary magnetic resonance angiography (CMRA) examination. MATERIALS AND METHODS: Ten healthy male volunteers (25-51 years old, 50-77 beats/min heart rate) were enrolled in this prospective study. A motion area map was generated from a cine image set by extracting high-speed component of cardiac motion, and it was used to specify the rest period in the proposed CMRA...
July 7, 2018: Clinical Imaging
Thanh Dinh Nguyen, Gaoke Feng, Xin Yi, Yongnan Lyu, Zhiyuan Lan, Jinggang Xia, Tim Wu, Xuejun Jiang
Objective Using coronary angiography and intravascular ultrasound methods to evaluate the performance of the novel fully bioabsorbable scaffold (NFBS) composed of poly-L-lactic acid/amorphous calcium phosphate (PLLA/ACP) at six-month follow-up by comparing with PLLA scaffolds Methods Twelve PLLA/ACP scaffolds and 12 PLLA scaffolds were implanted into the coronary arteries of 12 miniature pigs. Quantitative coronary angiography (QCA) was used to measure the reference vessel diameter (RVD), mean lumen diameter (MLD) and late lumen loss (LLL)...
August 2018: Journal of Biomaterials Applications
Wei Fang, Cai-Hong Wang, Yi-Fan Yu, Li-Huan Wang, Dan-Hua Tang, Da-Bo Xu, Zuo-Yun Ding, Wen-Hao Gu
This study aims to evaluate the feasibility of performing coronary computed tomography angiography (CCTA) and abdominal enhanced computed tomography (CT) with 1-time injection of the agent.CCTA images (right coronary artery, left anterior descending coronary artery, and left circumflex coronary artery) were collected from 20 patients who completed a 1-stop combined examination of CCTA and abdominal enhanced CT (group A), 20 patients who only underwent abdominal enhanced CT (group B1), and 20 patients who only underwent CCTA (group B2)...
August 2018: Medicine (Baltimore)
Charles Marcus, Prasanna Santhanam, Matthew J Kruse, Mehrbod S Javadi, Lilja B Solnes, Steven P Rowe
The aim of the present study was to evaluate the incidence of undiagnosed pulmonary arterial dilatation using the gated computed tomography (CT) images acquired in patients with an otherwise normal Tc-sestamibi single-photon-emission CT (SPECT)/CT myocardial perfusion study.This was a retrospective review of 200 consecutive patients (100 men, mean age 58.7 years) who underwent a myocardial perfusion Tc-sestamibi SPECT/CT study with normal perfusion and with gated CT images acquired for coronary calcium scoring...
August 2018: Medicine (Baltimore)
Maurizio Bertaina, Ovidio De Filippo, Mario Iannaccone, Antonio Colombo, Gregg Stone, Patrick Serruys, Massimo Mancone, Pierluigi Omedè, Federico Conrotto, Mauro Pennone, Takeshi Kimura, Hiroyoshi Kawamoto, Giuseppe Biondi Zoccai, Imad Sheiban, Christian Templin, Umberto Benedetto, Rafael Cavalcante, Maurizio D'Amico, Mario Gaudino, Claudio Moretti, Fiorenzo Gaita, Fabrizio D'Ascenzo
BACKGROUND: Treatment of patients with ULMCA (unprotected left main coronary artery disease) with percutaneous coronary intervention (PCI) has been compared with coronary artery bypass graft (CABG), without conclusive results. METHODS: All randomized controlled trials (RCTs) and observational studies with multivariate analysis comparing PCI and CABG for ULMCA were included. Major cardiovascular events (MACEs, composite of all-cause death, MI, definite or probable ST, target vessel revascularization and stroke) were the primary end points, whereas its single components were the secondary ones, along with stent thrombosis, graft occlusion and in-hospital death and stroke...
August 7, 2018: Journal of Cardiovascular Medicine
Alexandra Perel-Winkler, Sabahat Bokhari, Thania Perez-Recio, Afshin Zartoshti, Anca Askanase, Laura Geraldino-Pardilla
Objectives: Cardiovascular diseaseand heart failure (CHF) are leading causes of death in systemic lupus erythematosus (SLE). The underlying mechanisms for increased CHF in SLE are unclear but myocardial inflammation and lupus myocarditis (LM) may play a role. We propose that 18 F-fluorodeoxyglucose-positron emission tomography (18 F-FDG-PET)/CT can help diagnose LM. Methods: This report describes eight patients with presumed LM; five patients were evaluated due to active cardiorespiratory symptoms and three patients were participating in a pilot study to determine the prevalence of subclinical myocarditis in SLE...
2018: Lupus Science & Medicine
Jacob W Groenendyk, Nehal N Mehta
Atherogenesis has been well demonstrated to proceed in an ordinal fashion. Imaging technologies have advanced substantially in recent decades, enabling early detection of atherosclerosis. Some modalities, such as coronary CT, have seen broad clinical adaptation. In contrast, others, such as flow-mediated dilatation, remain predominantly research-based. Optimal and appropriate usage of these technologies remains an area of active investigation. We hypothesise that investigators ought to consider which stage of atherosclerosis is under investigation when choosing imaging modalities...
2018: Open Heart
Audrey Dionne, Ragui Ibrahim, Catherine Gebhard, Mitchel Benovoy, Mohamed Leye, Julie Déry, Chantale Lapierre, Patrice Girard, Anne Fournier, Nagib Dahdah
BACKGROUND: Coronary artery (CA) aneurysms are a serious complication of Kawasaki disease (KD). Conventional imaging techniques often described segments with regressed aneurysms as normal, whereas studies have shown significant endothelial dysfunction. METHODS: KD patients with aneurysms scheduled for routine coronary angiography underwent optical coherence tomography (OCT) imaging between 2013 and 2016. Microstructural coronary changes were compared between normal CA segments and those with dilation, regressed aneurysms, and persistent aneurysms...
June 1, 2018: Canadian Journal of Cardiology
Saima Mushtaq, Gianluca Pontone, Edoardo Conte, Marco Guglielmo, Elisa Consiglio, Marco Magatelli, Margarida Oliveira, Giuseppe Muscogiuri, Andrea Annoni, Andrea Baggiano, Alberto Formenti, Maria Elisabetta Mancini, Luca Di Odoardo, Eleonora Melotti, Cesare Fiorentini, Antonio L Bartorelli, Mauro Pepi, Daniele Andreini
RATIONALE AND OBJECTIVES: To evaluate image quality, coronary interpretability and radiation exposure of coronary CT angiography (CCTA) performed in patients with atrial fibrillation (AF) with the latest scanner generation, comparing two different technical approaches. A new scanner that combines a 0.23 mm spatial resolution, a new generation of iterative reconstruction, fast gantry rotation time and the intracycle motion-correction algorithm to improve the temporal resolution was recently introduced in the clinical field...
August 6, 2018: Academic Radiology
Michael Green, Edith M Marom, Eli Konen, Nahum Kiryati, Arnaldo Mayer
CCTA has become an important tool for coronary arteries assessment in low and medium risk patients. However, it exposes the patient to significant radiation doses, resulting from high image quality requirements and acquisitions at multiple cardiac phases. For widespread use of CCTA for coronary assessment, significant reduction of radiation exposure with minimal image quality loss is still needed. A neural denoising scheme, relying on a fully convolutional neural network (FCNN) architecture, is developed and applied to noisy CCTA...
July 29, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
Daisuke Nakamura, William Wijns, Matthew J Price, Michael R Jones, Emanuele Barbato, Takashi Akasaka, Stephen W-L Lee, Sandeep M Patel, Setsu Nishino, Wei Wang, Ajay Gopinath, Guilherme F Attizzani, David Holmes, Hiram G Bezerra
OBJECTIVES: This study sought to compare conventional methodology (CM) with a newly described optical coherence tomography (OCT)-derived volumetric stent expansion analysis in terms of fractional flow reserve (FFR)-derived physiology and device-oriented composite endpoints (DoCE). BACKGROUND: The analysis of coronary stent expansion with intracoronary imaging has used CM that relies on the analysis of selected single cross-sections for several decades. The introduction of OCT with its ability to perform semiautomated volumetric analysis opens opportunities to redefine optimal stent expansion...
August 13, 2018: JACC. Cardiovascular Interventions
Nathalie Annonay, Fatiha Challali, Marie-Noëlle Labour, Valérie Bockelée, A Garcia-Sanchez, Florent Tetard, Marie-Paule Besland, Philippe Djemia, Frédéric Chaubet
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December 2018: Bioactive Materials
G Harris-Bridge, L Young, I Handel, M Farish, C Mason, M A Mitchell, M J Haskell
Lameness in dairy cattle is a persistent problem, indicating pain caused by underlying disease states and is associated with reduced milk yields. Digital dermatitis is a common cause of lameness. Thermal imaging is a technique that may facilitate early detection of this disease and has the potential for use in automated detection systems. Previous studies with thermal imaging have imaged either the heels or the coronary band of the foot and typically only used the maximum temperature (Max) value as the outcome measure...
July 2018: Veterinary Journal
Kemin Huang, Yanlin Feng, Dejun Liu, Wen Li, Weitang Liang, Lin Li
OBJECTIVE: Conventional Single-photon emission tomography (SPET) myocardial perfusion imaging (MPI) is performed in the supine position range RAO 45o -LPO 45o , but the effect of other acquisition arcs on imaging quality have not been well described. In this study, we compared the radioactivity over left ventricle walls as measured by different acquisition arcs to identify the best specific applications. SUBJECTS AND METHODS: A total of 125 low-risk coronary heart disease patients underwent technetium-99m methoxy isobutyl isonitrile (99m Tc-MIBI) stress MPI, of which 52 received 360o acquisition with reconstruction using different 180o projections and the remaining 73 received conventional 180o (LPO 45o -RAO 45o ) and left-side 180o (POST 180o -ANT 0o ) acquisition consecutively...
May 2018: Hellenic Journal of Nuclear Medicine
Thomas D Stuckey, Roger S Gammon, Robi Goswami, Jeremiah P Depta, John A Steuter, Frederick J Meine, Michael C Roberts, Narendra Singh, Shyam Ramchandani, Tim Burton, Paul Grouchy, Ali Khosousi, Ian Shadforth, William E Sanders
BACKGROUND: Artificial intelligence (AI) techniques are increasingly applied to cardiovascular (CV) medicine in arenas ranging from genomics to cardiac imaging analysis. Cardiac Phase Space Tomography Analysis (cPSTA), employing machine-learned linear models from an elastic net method optimized by a genetic algorithm, analyzes thoracic phase signals to identify unique mathematical and tomographic features associated with the presence of flow-limiting coronary artery disease (CAD). This novel approach does not require radiation, contrast media, exercise, or pharmacological stress...
2018: PloS One
Mingxin Jin, Dongdong Hao, Song Ding, Binjie Qin
This letter proposes to extract contrast-filled vessels from the overlapped noisy complex backgrounds in X-ray coronary angiogram image sequence using low-rank and sparse decomposition. A refined vessel segmentation is finally achieved by implementing Radon-like feature filtering plus local-to-global adaptive thresholding to tackle the spatially varying noisy residuals in the extracted vessels. Based on real and synthetic XCA data, experiment results show the superiority of the proposed method over the state-of-the-art methods...
August 8, 2018: Physics in Medicine and Biology
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