Mariana Lucy Mesquita Ramos, Fernando Almeida-Silva, Vanessa Brito de Souza Rabello, Juliana Nahal, Maria Helena Galdino Figueiredo-Carvalho, Andrea Reis Bernardes-Engemann, Vanice Rodrigues Poester, Melissa Orzechowski Xavier, Wieland Meyer, Rosely Maria Zancopé-Oliveira, Susana Frases, Rodrigo Almeida-Paes
The drugs available to treat sporotrichosis, an important yet neglected fungal infection, are limited. Some Sporothrix spp. strains present reduced susceptibility to these antifungals. Furthermore, some patients may not be indicated to use these drugs, while others may not respond to the therapy. The anthelmintic drug niclosamide is fungicidal against the Sporothrix brasiliensis type strain. This study aimed to evaluate whether niclosamide also has antifungal activity against Sporothrix globosa, Sporothrix schenckii and other S...
March 11, 2024: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]